Interactions on record — worth a quick check against your medications. Based on 6 of 7 ingredients. Check your meds →
Dietary supplement

Immune Assist Complete Ingredients & Drug Interactions

by Aloha Medicinals

Immune Assist Complete label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Immune Assist Complete against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Immune Assist Complete is a dietary supplement by Aloha Medicinals with 7 active ingredients. Its ingredients are commonly taken for thyroid support, iodine source, weight management.Based on those ingredients, 1,167 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Kelp, organic Ganoderma lucidum extract, organic Lentinula edodes extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Immune Assist Complete by Aloha Medicinals

Ask about any prescription or over-the-counter medication and we check it for interactions with Immune Assist Complete by Aloha Medicinals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Immune Assist Complete by Aloha Medicinals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 7 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1 Gram(s)) without saying how much of each component you get.

Immune Assist Complete contains 7 ingredients total, most of them mushroom extracts. The active ingredients are kelp (a sea plant high in iodine), organic agaricus mushroom, organic cordyceps, organic coriolus versicolor, organic reishi mushroom, organic maitake mushroom, and organic shiitake mushroom extract.

Together they're in a proprietary blend, so individual doses aren't listed on the label. The capsule is made of vegetarian pullulan, and the product includes 100% organic white milo as an inactive ingredient.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: immune support and thyroid health.
  • We looked for evidence on: Common cold, Influenza, Coronavirus disease 2019 (COVID-19), Hypothyroidism, Autoimmune thyroiditis, immune function — and 2 related terms.
  • The closest evidence on file: Maitake Mushroom is rated "Insufficient Reliable Evidence To Rate" for Coronavirus disease 2019 (COVID-19) (Natural Medicines).
  • Also on file: Cordyceps is rated "Insufficient Reliable Evidence To Rate" for Autoimmune thyroiditis.
  • Also on file: Shiitake Mushroom is rated "Insufficient Reliable Evidence To Rate" for Common cold, Influenza, Coronavirus disease 2019 (COVID-19).

The evidence we hold doesn't establish that any of these ingredients work for specific health goals. Kelp is rated insufficient evidence for aging skin, cardiovascular disease, constipation, diarrhea, and digestive upset.

Agaricus mushroom shows insufficient evidence for hay fever, bone loss, cancer, heart disease, chemotherapy side effects, and Crohn disease. Cordyceps appears possibly ineffective for athletic performance and has insufficient evidence for sexual function, heart rhythm, asthma, lung cancer, and COPD.

Reishi mushroom is possibly ineffective for high cholesterol and has insufficient evidence for altitude sickness, Alzheimer disease, and athletic performance. Maitake and shiitake mushrooms show insufficient evidence for multiple conditions.

Without established effectiveness in our data, talk with your doctor about whether this product makes sense for what you're trying to achieve.

The evidence, ingredient by ingredient Fucus Vesiculosus Agaricus Mushroom Cordyceps Reishi Mushroom Maitake Mushroom Shiitake Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Kelp is the ingredient with the most significant safety concerns. Orally, it's considered unsafe due to variable and often very high iodine content, which can disrupt thyroid function and the plant may concentrate heavy metals from seawater.

The agaricus and cordyceps mushrooms are generally well tolerated, though agaricus can rarely cause serious liver damage or allergic reactions, and cordyceps has a rare case report of liver inflammation. Reishi, maitake, and shiitake mushrooms are generally well tolerated when used short-term, though they may cause mild digestive upset, dizziness, itching, or rash in some people.

Shiitake dermatitis (a whip-like skin eruption) can occur with raw or undercooked mushroom, and shiitake spore inhalation has caused severe breathing problems in workers. During pregnancy, kelp is specifically flagged as unsafe due to excess iodine and possible heavy metals.

Agaricus, cordyceps, reishi, maitake, and shiitake all lack enough safety data — the evidence advises against supplement doses in pregnancy. During breastfeeding, kelp is unsafe because iodine passes into breast milk and may affect your baby's thyroid.

The mushroom ingredients similarly lack enough data for breastfeeding safety. If you're pregnant, nursing, or planning either, talk with your own doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Fucus Vesiculosus Agaricus Mushroom Cordyceps Reishi Mushroom Maitake Mushroom Shiitake Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Maitake Mushroom, Cordyceps, Shiitake Mushroom, Fucus Vesiculosus, Reishi Mushroom, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 1,168 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Immune Assist Complete, double-check with your own doctor or pharmacist if you take lithium (risk of overactive thyroid), blood pressure medications, diabetes drugs, blood thinners including warfarin, heart rhythm drugs like amiodarone, immune-suppressing medications, or any drug that relies on liver enzymes (CYP2D6, CYP2C9, or CYP3A4) to be broken down — the interactions documented span multiple medication types and severities. The most serious documented interaction is kelp with lithium.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Immune Assist Complete is a blend of mushroom extracts and kelp. The evidence we hold doesn't confirm these ingredients work for any specific condition, but several of them — especially kelp — carry real interaction risks with common medications like blood pressure drugs, diabetes medications, blood thinners, and lithium.

If you take any prescription medication, check it against this product using the tool on this page, and discuss with your own doctor or pharmacist before you start, especially if you're pregnant, breastfeeding, or on lithium or thyroid medication.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Immune Assist Complete, straight from the product label.

Brand Aloha Medicinals
Barcode (UPC) 835186001042
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 218850
Product type Botanical
Supplement form Capsule
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Immune Assist Complete by Aloha Medicinals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
835186001042
IngredientAmount% DV
Proprietary Blend1 Gram(s)--
Kelp0 NP--
organic Agaricus blazei extract0 NP--
organic Cordyceps extract0 NP--
organic Coriolus versicolor extract0 NP--
organic Ganoderma lucidum extract0 NP--
organic Grifola frondosa extract0 NP--
organic Lentinula edodes extract0 NP--

Other ingredients: Vegetarian Pullulan Capsule, 100% organic White Milo

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Immune Assist Multi-Mineral Formula is formulated specifically to help the body fight off health threats from daily stress and our modern lifestyle challenges.

Advanced Immune Modulation Therapy

Certified Organic by QAI

Formula

Immune Assist Complete is formulated with Kelp (Laminara digitata) which contains naturally occuring iodine, a mineral known to support healthy thyroid function.

Made with Authentic Immune Assist Micron Multi-mineral formula

Suggested/Recommended/Usage/Directions

Suggested use: Take two capsules daily with food.

Precautions

As with any supplement, if you are pregnant, nursing or taking any medication, consult your healthcare provider before use.

Do not use if tamper evident seal is broken

General Statements

100% American Growth

Please recycle bottle after use.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

100% Made in USA

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Immune Assist Complete by Aloha Medicinals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Immune Assist Complete label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Immune Assist Complete by Aloha Medicinals

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1 Gram(s) per serving

Other (inactive) ingredients: Vegetarian Pullulan Capsule, 100% organic White Milo. These complete the product’s ingredient list but are not active constituents.

Interaction report

Immune Assist Complete by Aloha Medicinals Drug Interactions

Want to check YOUR meds against Immune Assist Complete?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,167Drugs
677 Moderate 490 Minor

Ingredients driving the most interactions

Kelp 891
organic Ganoderma lucidum extract 375
organic Lentinula edodes extract 312
organic Grifola frondosa extract 260
organic Cordyceps extract 249

Individual Drug Interactions

The ingredients in Immune Assist Complete interact with 1,167 drugs. Click any drug to see the details.

6 of the 7 ingredients in Immune Assist Complete interact with drugs. Each result below shows which ingredient is responsible. Kelp organic Ganoderma lucidum extract organic Lentinula edodes extract organic Grifola frondosa extract organic Cordyceps extract organic Agaricus blazei extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Immune Assist Complete with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Kelp9 drug types · 891 drugs

Amiodarone (Cordarone)

Theoretically, combining Fucus vesiculosus with amiodarone might cause excessively high iodine levels.
Fucus vesiculosus contains high concentrations of iodine. Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.

Likelihood Probable Evidence D
Antithyroid Drugs

Due to its iodine content, Fucus vesiculosus might alter the effects of antithyroid drugs.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using antithyroid drugs could alter the effects of the antithyroid drugs.

Likelihood Possible Evidence D
Lithium

Concomitant use of Fucus vesiculosus and lithium has resulted in hyperthyroidism.
There is a case of hyperthyroidism occurring in a patient taking Fucus vesiculosus and lithium. Monitor thyroid hormones closely in patients taking lithium and Fucus vesiculosus concomitantly.

Likelihood Possible Evidence D
Thyroid Hormone

Due to its iodine content, Fucus vesiculosus might alter the effects of thyroid hormone.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using thyroid hormone could alter the effects of thyroid hormone.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
In vitro evidence suggests that a constituent of Fucus vesiculosus, known as fucoidan, has anticoagulant effects. However, in clinical research, fucoidan does not seem to have significant anticoagulant activity when taken orally, possibly due to poor absorption.

Likelihood Unlikely Evidence D
Cytochrome P450 2C8 (Cyp2C8) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP2C8 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C8. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C9. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, both inhibits and induces CYP2D6. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP3A4. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Kelp full monograph & interactions

organic Ganoderma lucidum extract3 drug types · 375 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, high doses of reishi mushroom might increase the risk of bleeding.
A dose of 1.5 grams daily of reishi mushroom does not seem to decrease platelet aggregation, but a higher dose of 3 grams daily does.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, reishi mushroom might have additive effects with antidiabetes drugs.
Animal research suggests that reishi mushroom decreases blood sugar. However, in patients with type 2 diabetes, taking reishi mushroom does not reduce fasting glucose levels, and its effects on glycated hemoglobin are inconsistent.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concurrent use of reishi mushroom with antihypertensive drugs might increase the risk of hypotension.
Reishi mushroom has shown hypotensive activity in animal research. Clinical evidence suggests that reishi mushroom reduces blood pressure in some, but not all, patients with hypertension.

Likelihood Possible Evidence D
organic Ganoderma lucidum extract full monograph & interactions

organic Lentinula edodes extract2 drug types · 312 drugs

Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
In vitro studies suggest that the shiitake mushroom extract AHCC might induce the CYP2D6 enzyme. This effect has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking shiitake mushroom might decrease the effects of immunosuppressive therapy.
In vitro evidence suggests that shiitake mushroom extracts stimulate immune function.

Likelihood Possible Evidence D
organic Lentinula edodes extract full monograph & interactions

organic Grifola frondosa extract3 drug types · 260 drugs

Antidiabetes Drugs

Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that maitake mushroom can lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects.

Likelihood Possible Evidence D
organic Grifola frondosa extract full monograph & interactions

organic Cordyceps extract3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
organic Cordyceps extract full monograph & interactions

organic Agaricus blazei extract1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking agaricus mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
In one clinical study in patients with type 2 diabetes who are stabilized on conventional oral hypoglycemic agents, 3 of 29 patients taking an agaricus mushroom extract 500 mg three times daily for 12 weeks reported hypoglycemia, compared to one of 29 patients in the placebo group.

Likelihood Possible Evidence D
organic Agaricus blazei extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Immune Assist Complete, from the product label.

Aloha Medicinals

See all Aloha Medicinals products
Name
Aloha Medicinals
Street Address
2300 Arrowhead Dr
City
Carson City
State
NV
ZipCode
89706
Phone Number
877-835-6091
Web Address
www.alohamedicinals.com
Pharmacist Counseling Corner

Immune Assist Complete by Aloha Medicinals: Common Questions

Does Immune Assist Complete by Aloha Medicinals interact with any medications?
Yes. Based on its ingredients, Immune Assist Complete has a known interaction with 1,167 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Immune Assist Complete contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is kelp and why is it in this product?
Kelp is a sea plant packed with iodine. It's included for immune support, though the evidence we hold doesn't confirm it works. The main safety issue is that kelp's iodine content can be extremely high and variable — enough to disrupt thyroid function if you eat too much or if you're taking thyroid or blood pressure medications.
Can I take this if I'm on thyroid medication?
Not without checking first. Kelp in this product contains high iodine, which can interfere with how thyroid medications work. Talk with your doctor or pharmacist before you start — they may need to monitor your thyroid levels more closely.
Is this safe during pregnancy?
No. Kelp is unsafe in pregnancy due to excess iodine and possible heavy metal content. The mushroom ingredients lack enough safety data to say they're okay in pregnancy either. Talk with your own doctor or pharmacist before taking it if you're pregnant or planning to become pregnant.
What does the 'proprietary blend' mean?
It means the manufacturers combined all the active ingredients (the kelp and five mushroom extracts) in one mix, but they don't list the exact dose of each ingredient on the label — only the total weight of the blend. You'll know you're getting all of them, but not how much of each one.
Can I take this with blood pressure or diabetes medication?
The mushroom ingredients in this product may lower blood pressure and blood sugar further, which could cause problems if your medications already do that. Check with your own doctor or pharmacist before you combine this product with either type of medication.
What side effects has this product been reported to cause?
Individual reports are rare, but the ingredients can cause mild digestive upset (nausea, diarrhea, abdominal discomfort), dizziness, or rash. Kelp carries the bigger risk — overuse has caused goiter, overactive thyroid, or underactive thyroid. If you experience thyroid symptoms or severe allergic reactions, stop and contact your doctor right away.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Immune Assist Complete label
Go deeper

The Full Monographs Behind Immune Assist Complete’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Fucus Vesiculosus

Interacts with 891 drugs

Fucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin. There is little solid human evidence to support mo...

Read the full Fucus Vesiculosus monograph → Herb & supplement monograph

Agaricus Mushroom

Interacts with 86 drugs

Agaricus mushroom (often Agaricus blazei/subrufescens) is a culinary and medicinal mushroom studied mostly for possible immune and antioxidant effects. The human evidence is limited and not...

Read the full Agaricus Mushroom monograph → Herb & supplement monograph

Cordyceps

Interacts with 249 drugs

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...

Read the full Cordyceps monograph → Herb & supplement monograph

Reishi Mushroom

Interacts with 375 drugs

Reishi is a traditional Asian mushroom widely used to support the immune system and overall wellness. Human evidence for most of its claimed benefits is limited or low-quality, so it should...

Read the full Reishi Mushroom monograph → Herb & supplement monograph

Maitake Mushroom

Interacts with 260 drugs

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and blood pressure effects. The human evidence...

Read the full Maitake Mushroom monograph → Herb & supplement monograph

Shiitake Mushroom

Interacts with 312 drugs

Shiitake is a popular edible mushroom that is nutritious and safe to eat as food for most people. Some of its extracts (like lentinan and AHCC) have been studied as immune support, mainly al...

Read the full Shiitake Mushroom monograph →
Sources

Sources & How We Checked

Immune Assist Complete's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 126 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fucus Vesiculosus 15 references
  1. Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  3. Phaneuf D, Cote I, Dumas P, et al. Evaluation of the contamination of marine algae (Seaweed) from the St. Lawrence River and likely to be consumed by humans. Environ Res 1999;80:S175-S182. PubMed
  4. Durig J, Bruhn T, Zurborn KH, et al. Anticoagulant fucoidan fractions from Fucus vesiculosus induce platelet activation in vitro. Thromb Res 1997;85:479-91. PubMed
  5. Conz PA, La Greca G, Benedetti P, et al. Fucus vesiculosus: a nephrotoxic alga? Nephrol Dial Transplant 1998;13:526-7.
  6. Ohye H, Fukata S, Kanoh M, et al. Thyrotoxicosis caused by weight-reducing herbal medicines. Arch Intern Med 2005;165:831-4. PubMed
  7. Okamura K, Inoue K, Omae T. A case of Hashimoto's thyroiditis with thyroid immunological abnormality manifested after habitual ingestion of seaweed. Acta Endocrinol (Copenh) 1978;88:703-12. PubMed
  8. Agarwal SC, Crook JR, Pepper CB. Herbal remedies -- how safe are they? A case report of polymorphic ventricular tachycardia/ventricular fibrillation induced by herbal medication used for obesity. Int J Cardiol 2006;106:260-1. PubMed
  9. Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
  10. Catania, M. A., Oteri, A., Caiello, P., Russo, A., Salvo, F., Giustini, E. S., Caputi, A. P., and Polimeni, G. Hemorrhagic cystitis induced by an herbal mixture. South.Med.J. 2010;103(1):90-92. PubMed
  11. Cumashi, A., Ushakova, N. A., Preobrazhenskaya, M. E., D'Incecco, A., Piccoli, A., Totani, L., Tinari, N., Morozevich, G. E., Berman, A. E., Bilan, M. I., Usov, A. I., Ustyuzhanina, N. E., Grachev, A. A., Sanderson, C. J., Kelly, M., Rabinovich, G. A., I
  12. Irhimeh, M. R., Fitton, J. H., and Lowenthal, R. M. Pilot clinical study to evaluate the anticoagulant activity of fucoidan. Blood Coagul.Fibrinolysis 2009;20(7):607-610. PubMed
  13. Arbaizar, B. and Llorca, J. [Fucus vesiculosus induced hyperthyroidism in a patient undergoing concomitant treatment with lithium]. Actas Esp.Psiquiatr. 2011;39(6):401-403.
  14. Church FC, Meade JB, Treanor RE, and et al. Antithrombin activity of fucoidan. The interaction of fucoidan with heparin cofactor II, antithrombin III, and thrombin. J Biol Chem 2-25-1989;264(6):3618-3623. DOI
  15. Mathew L, Burney M, Gaikwad A, et al. Preclinical evaluation of safety of fucoidan extracts from Undaria pinnatifida and Fucus vesiculosus for use in cancer treatment. Integr Cancer Ther 2017;16(4):572-84.

See these in context on the Fucus Vesiculosus monograph →

Agaricus Mushroom 5 references
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Cordyceps 14 references
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Reishi Mushroom 17 references
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Maitake Mushroom 8 references
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Shiitake Mushroom 67 references
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