Interactions on record — worth a quick check against your medications. Based on 6 of 8 ingredients. Check your meds →
Dietary supplement

Levolar Forte Ingredients & Drug Interactions

by Aloha Medicinals

Levolar Forte label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Levolar Forte against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Levolar Forte is a dietary supplement by Aloha Medicinals with 8 active ingredients. Its ingredients are commonly taken for hair growth and thinning hair, brittle nails, skin health.Based on those ingredients, 534 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Grifola frondosa extract, Cinnamon (Cinnamon zeylanicum) extract, organic Cordyceps sinensis. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Levolar Forte by Aloha Medicinals

Ask about any prescription or over-the-counter medication and we check it for interactions with Levolar Forte by Aloha Medicinals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Levolar Forte by Aloha Medicinals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 2 of its 8 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1.50 Gram(s)) without saying how much of each component you get.

Levolar Forte contains 8 active ingredients. Biotin is a B vitamin that supports hair, skin, and nail health and is likely effective for biotin deficiency.

Chromium is a mineral involved in blood sugar regulation. The proprietary blend includes maitake mushroom (Grifola frondosa), Ceylon cinnamon, salacia, two species of cordyceps (Cordyceps sinensis and Cordyceps militaris), and organic Coprinus comatus extract.

The tablet also contains several inactive ingredients—tapioca maltodextrin, tapioca syrup, Nu-Flow, carnauba wax, cellulose coating, and white milo—which serve as binders, fillers, and coating materials.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: help maintain healthy glucose and insulin metabolism.
  • We looked for evidence on: Biotin deficiency, Brittle nails, Chromium deficiency, Diabetes, Hypercholesterolemia, Hyperlipidemia — and 4 related terms.
  • The strongest evidence on file: Biotin is rated "Likely Effective" for Biotin deficiency (Natural Medicines).
  • Also on file: Chromium is rated "Likely Effective" for Chromium deficiency.
  • Also on file: Chromium is rated "Possibly Effective" for Diabetes.

Biotin is likely effective for biotin deficiency but only possibly ineffective or has insufficient evidence for multiple sclerosis, seborrheic dermatitis, and alopecia areata. Chromium is likely effective for chromium deficiency and possibly effective for diabetes, though possibly ineffective for prediabetes and other conditions.

Ceylon cinnamon is possibly ineffective for diabetes and obesity, with insufficient evidence for hay fever, COPD, and colds. Maitake mushroom, salacia, and both cordyceps species all carry insufficient evidence ratings for their traditional uses—we don't have solid proof they work for allergic rhinitis, chronic fatigue, sexual dysfunction, athletic performance, or the other conditions listed.

The evidence on this product's overall effectiveness is not well established in the data we hold.

The evidence, ingredient by ingredient Biotin Maitake Mushroom Ceylon Cinnamon Salacia Cordyceps Chromium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Biotin is likely safe in pregnancy and lactation and generally well tolerated, though high doses have rarely caused mild diarrhea. One rare case report linked high-dose biotin plus pantothenic acid to a chest and heart inflammation, but causality is unclear.

Chromium is likely safe in pregnancy and lactation at typical doses but warrants caution with high or long-term doses; rare serious effects like kidney damage and blood cell problems have been reported. Maitake mushroom should be avoided in pregnancy and lactation—there isn't enough safety data.

Ceylon cinnamon is likely safe in pregnancy but likely unsafe in some pregnancy contexts and has unknown breastfeeding safety; food amounts are fine but supplement doses need medical approval. Salacia and both cordyceps should be avoided in pregnancy and breastfeeding due to insufficient data.

Common side effects across these ingredients include gastrointestinal upset (bloating, nausea, diarrhea, abdominal pain), and rare allergic reactions and skin rashes have been reported with some ingredients.

Side effects, ingredient by ingredient Biotin Maitake Mushroom Ceylon Cinnamon Salacia Cordyceps Chromium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Ceylon Cinnamon, Maitake Mushroom, Cordyceps, Chromium, Salacia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 534 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Levolar Forte, check with your doctor or pharmacist if you take antidiabetes drugs or insulin (due to a Moderate risk of low blood sugar from chromium, maitake, cinnamon, or salacia), blood pressure–lowering medications (maitake and cinnamon), warfarin or other blood thinners (maitake mushroom and the cordyceps species pose a Moderate risk of bleeding), levothyroxine or other thyroid hormone (chromium may reduce absorption), or immunosuppressants like cyclosporine (cordyceps may interfere). NSAIDs, aspirin, and testosterone medications carry Minor interactions with chromium or cordyceps.

No interactions are documented for the one ingredient we could not check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Levolar Forte is a multi-ingredient supplement aimed at hair, skin, and metabolic support, but the evidence for most of its ingredients is limited or insufficient. If you take any medications—especially diabetes drugs, thyroid hormone, blood thinners, blood pressure medications, or immunosuppressants—you should check your specific prescriptions with your doctor or pharmacist before starting this product.

Pregnant or breastfeeding people should talk with their healthcare provider first, as several ingredients lack safety data in those situations.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Levolar Forte, straight from the product label.

Brand Aloha Medicinals
Barcode (UPC) 835186007044
Net contents 120 Tablet(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 218846
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Levolar Forte by Aloha Medicinals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
60
UPC/BARCODE
835186007044
IngredientAmount% DV
Biotin4050 mcg1350%
Proprietary Blend1.5 Gram(s)--
Chromium525 mcg150%
organic Grifola frondosa extract0 NP--
Cinnamon (Cinnamon zeylanicum) extract0 NP--
Salacia oblonga extract0 NP--
organic Cordyceps sinensis0 NP--
organic Cordyceps militaris0 NP--
organic Coprinus comatus extract0 NP--

Other ingredients: Tapioca Maltodextrin, Tapioca Syrup, organic Nu-Flow, organic Carnauba Wax, Cellulose Coating, organic White Milo

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Levolar forte is a daily dietary supplement formulated to help maintain healthy regulation of glucose and insulin metabolism.

All natural Advanced Beta Glucan Therapy Glucose support formula

Suggested/Recommended/Usage/Directions

Recommended use: Two (2) tablets twice a day with meals or as directed by your healthcare provider. May be increased to 2 tablets 3 times daily.

Precautions

As with any supplement, if you are pregnant, nursing or taking any medication, consult a healthcare provider before use.

Do not use if tamper evident seal is broken

General Statements

100% American Growth

Seals/Symbols

Made in USA

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Levolar Forte by Aloha Medicinals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Levolar Forte label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Levolar Forte by Aloha Medicinals

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Biotin

No known
interactions
4050 mcg per serving

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get...

Biotin monograph & interactions

Proprietary Blend

1.5 Gram(s) per serving

Chromium

Interacts with
178 drugs
525 mcg per serving Form: Chromium Nicotinate Glycinate Chelate

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

Other (inactive) ingredients: Tapioca Maltodextrin, Tapioca Syrup, Organic Nu-Flow, Organic Carnauba Wax, Cellulose Coating, Organic White Milo. These complete the product’s ingredient list but are not active constituents.

Interaction report

Levolar Forte by Aloha Medicinals Drug Interactions

Want to check YOUR meds against Levolar Forte?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
534Drugs
497 Moderate 37 Minor

Ingredients driving the most interactions

organic Grifola frondosa extract 260
Cinnamon (Cinnamon zeylanicum) extract 258
organic Cordyceps sinensis 249
Chromium 178
Salacia oblonga extract 86

Individual Drug Interactions

The ingredients in Levolar Forte interact with 534 drugs. Click any drug to see the details.

5 of the 8 ingredients in Levolar Forte interact with drugs. Each result below shows which ingredient is responsible. organic Grifola frondosa extract Cinnamon (Cinnamon zeylanicum) extract organic Cordyceps sinensis Chromium Salacia oblonga extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Levolar Forte with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Grifola frondosa extract3 drug types · 260 drugs

Antidiabetes Drugs

Theoretically, combining maitake mushroom with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking maitake mushroom polysaccharide (MMP) can lower blood glucose levels in patients with types 2 diabetes.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, combining maitake mushroom with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that maitake mushroom can lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that maitake mushroom may increase the anticoagulant effects of warfarin.
In a case report, a patient previously stabilized on warfarin developed an elevated international normalized ratio (INR) of 5.1 after taking maitake mushroom (Grifron-Pro Maitake D-Fraction) 1 drop/kg daily in three divided doses for one week. The elevated INR resolved after holding warfarin for two days, then reducing the dose by 11%. It is thought that the beta-glucan constituent of maitake mushroom might cause warfarin dissociation from proteins, resulting in increased free warfarin levels and increased warfarin effects.

Likelihood Possible Evidence D
organic Grifola frondosa extract full monograph & interactions

Cinnamon (Cinnamon zeylanicum) extract2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, Ceylon cinnamon may have additive effects with antidiabetes drugs.
Ceylon cinnamon may lower blood glucose levels. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Animal research shows that Ceylon cinnamon extract has vasorelaxant properties and reduces blood pressure in rat models of hypertension, possibly via inhibition of calcium influx through L-type voltage-sensitive channels.

Likelihood Possible Evidence D
Cinnamon (Cinnamon zeylanicum) extract full monograph & interactions

organic Cordyceps sinensis3 drug types · 249 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cordyceps may increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro and animal research suggests that cordyceps extract inhibits platelet aggregation and function. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of cordyceps might interfere with immunosuppressive therapy.
Animal and in vitro research suggests that cordyceps stimulates the immune system. However, limited clinical research suggests that taking cordyceps may lower the necessary therapeutic dose of the immunosuppressant cyclosporine, which suggests that cordyceps may have an immunosuppressive effect.

Likelihood Possible Evidence B
Testosterone

Theoretically, concurrent use of cordyceps and testosterone might have additive effects.
Animal research suggests that cordyceps can increase testosterone levels. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
organic Cordyceps sinensis full monograph & interactions

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
Chromium full monograph & interactions

Salacia oblonga extract1 drug type · 86 drugs

Antidiabetes Drugs

Salacia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research suggests that salacia might lower blood glucose levels.

Likelihood Probable Evidence D
Salacia oblonga extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Levolar Forte, from the product label.

Aloha Medicinals

See all Aloha Medicinals products
Name
Aloha Medicinals
Street Address
2300 Arrowhead Dr
City
Carson City
State
NV
ZipCode
89706
Phone Number
877-835-6091
Web Address
www.alohamedicinals.com
Pharmacist Counseling Corner

Levolar Forte by Aloha Medicinals: Common Questions

Does Levolar Forte by Aloha Medicinals interact with any medications?
Yes. Based on its ingredients, Levolar Forte has a known interaction with 534 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Levolar Forte contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is biotin safe to take if I'm pregnant or breastfeeding?
Biotin is rated likely safe in pregnancy and lactation. Normal dietary and supplement amounts are considered acceptable, though you should check with your doctor before taking high-dose biotin supplements to be sure.
Can I take this product if I'm on medication for diabetes or blood pressure?
That depends on your specific drugs and doses. Several ingredients in this product—chromium, maitake, cinnamon, and salacia—may lower blood sugar or blood pressure, so combining them with your medications could cause too low a level. Talk with your doctor or pharmacist first to see whether it's safe for you.
What does biotin do, and does it really help hair and nails?
Biotin is a B vitamin likely effective for biotin deficiency but only has insufficient or possibly ineffective evidence for hair loss, nail health, or skin conditions like dermatitis. The ingredient list doesn't specify what this product is designed for.
Are there common side effects I should expect?
Gastrointestinal upset—including nausea, diarrhea, bloating, and stomach pain—is the most common side effect across these ingredients. These effects are often mild and dose-dependent, and taking cordyceps with food may help reduce them.
Should I avoid this product if I'm taking a blood thinner like warfarin?
Maitake mushroom and the cordyceps ingredients may interact with blood thinners, so yes—talk with your doctor or pharmacist before starting Levolar Forte if you take warfarin or other anticoagulants.
What about the ingredient I saw listed as 'organic Coprinus comatus extract'—what is that for?
We don't hold any data on that ingredient, so we can't tell you what it does or how it might affect your medications. Bring this product's label to your pharmacist or doctor, and they can help you find more information about it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Levolar Forte is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Levolar Forte label
Go deeper

The Full Monographs Behind Levolar Forte’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Biotin

Biotin (vitamin B7) is a water-soluble vitamin your body needs to turn food into energy and to support healthy hair, skin, and nails. Most people get plenty from a normal diet, and true defi...

Read the full Biotin monograph → Herb & supplement monograph

Maitake Mushroom

Interacts with 260 drugs

Maitake is an edible mushroom long used as food and in traditional Japanese medicine, and it is being studied for possible immune, blood sugar, and blood pressure effects. The human evidence...

Read the full Maitake Mushroom monograph → Herb & supplement monograph

Ceylon Cinnamon

Interacts with 258 drugs

Ceylon cinnamon is the so-called 'true' cinnamon, valued as a spice and used in traditional medicine for blood sugar, cholesterol, and digestion. Evidence for most health benefits is limited...

Read the full Ceylon Cinnamon monograph → Herb & supplement monograph

Salacia

Interacts with 86 drugs

Salacia is a plant used in Ayurvedic medicine, mostly studied for lowering blood sugar after meals. Some small human studies suggest it may modestly blunt blood sugar spikes, but the evidenc...

Read the full Salacia monograph → Herb & supplement monograph

Cordyceps

Interacts with 249 drugs

Cordyceps is a fungus used in traditional Chinese medicine for energy, exercise performance, and lung and immune support. Human research is limited and mostly low quality, so its benefits ar...

Read the full Cordyceps monograph → Herb & supplement monograph

Chromium

Interacts with 178 drugs

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control in certain people with type 2 diabetes, b...

Read the full Chromium monograph →
Sources

Sources & How We Checked

Levolar Forte's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 106 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Biotin 4 references
  1. Debourdeau PM, Djezzar S, Estival JL, et al. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother 2001;35:424-6. DOI
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Mock DM, Quirk JG, Mock NI. Marginal biotin deficiency during normal pregnancy. Am J Clin Nutr 2002;75:295-9. PubMed
  4. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progressive multiple sclerosis: a pilot study.Mult Scler Relat Disord. 2015;4(2):159-69. doi: 10.1016/j.msard.2015.01.005. PubMed

See these in context on the Biotin monograph →

Chromium 53 references
  1. Cerulli J, Grabe DW, Gauthier I, et al. Chromium picolinate toxicity. Ann Pharmacother 1998;32:428-31. PubMed
  2. Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism 1987;36:896-9. PubMed
  3. Mohamedshah FY, Moser-Veillon PB, Yamini S, et al. Distribution of a stable isotope of chromium (53Cr) in serum, urine, and breast milk in lactating women. Am J Clin Nutr 1998;67:1250-5. PubMed
  4. Wasser WG, Feldman NS, D'Agati VD. Chronic renal failure after ingestion of over-the-counter chromium picolinate. [letter]. Ann Intern Med 1997;126:410. PubMed
  5. Mertz W. Interaction of chromium with insulin: a progress report. Nutr Rev 1998;56:174-7. PubMed
  6. Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998;17:548-55. PubMed
  7. McLeod MN, Gaynes BN, Golden RN. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. J Clin Psych 1999;60:237-40. PubMed
  8. Fowler JF Jr. Systemic contact dermatitis caused by oral chromium picolinate. Cutis 2000;65:116. DOI
  9. Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness 1995;35:273-80.
  10. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  11. Rabinovitz H, Friedensohn A, Leibovitz A, et al. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res 2004;74:178-82. PubMed
  12. Lanca S, Alves A, Vieira AI, et al. Chromium-induced toxic hepatitis. Eur J Intern Med 2002;13:518-20. PubMed
  13. Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
  14. Davidson JR, Abraham K, Connor KM, McLeod MN. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biol Psychiatry 2003;53:261-4.. PubMed
  15. Food Standards Agency. Medicines and Healthcare products Regulatory Agency (MHRA). Expert Group on Vitamins and Minerals. Available at: http://cot.food.gov.uk/sites/default/files/vitmin2003.pdf.
  16. Mouser JF, Hak EB, Helms RA, et al. Chromium and zinc concentrations in pediatric patients receiving long-term parenteral nutrition. Am J Health Syst Pharm 1999;56:1950-6. PubMed
  17. Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
  18. Wani S, Weskamp C, Marple J, Spry L. Acute tubular necrosis associated with chromium picolinate-containing dietary supplement. Ann Pharmacother 2006;40:563-6. PubMed
  19. Kleefstra N, Houweling ST, Jansman FG, et al. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care 2006;29: PubMed
  20. Martin J, Wang ZQ, Zhang XH, et al. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care 2006;29:1826-32. PubMed
  21. Singer GM, Geohas J. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006;8:636-43. PubMed
  22. John-Kalarickal J, Pearlman G, Carlson HE. New medications which decrease levothyroxine absorption. Thyroid 2007;17:763-5. PubMed
  23. Yazaki Y, Faridi Z, Ma Y, et al. A pilot study of chromium picolinate for weight loss. J Altern Complement Med 2010;16:291-9. PubMed
  24. Davis ML, Seaborn CD, and Stoecker BJ. Effects of over-the-counter drugs on chromium retention and urinary excretion in rats. Nutrition Research 1995;15(2):201-210.
  25. Young P, Turiansky G, Bonner M, and et al. Acute generalized exanthematous pustulosis induced by chromium picolinate. J.Am Acad.Dermatol. 1999;41(5 Pt 2):820-823. PubMed
  26. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Lung cancer among workers in chromium chemical production. Am J Ind.Med 2000;38(2):115-126. DOI
  27. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Clinical findings of irritation among chromium chemical production workers. Am J Ind.Med 2000;38(2):127-131. PubMed
  28. Pittler, M. H. and Ernst, E. Dietary supplements for body-weight reduction: a systematic review. Am.J.Clin Nutr. 2004;79(4):529-536. PubMed
  29. Pei, D., Hsieh, C. H., Hung, Y. J., Li, J. C., Lee, C. H., and Kuo, S. W. The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Metabolism 2 PubMed
  30. Hisatomi, K., Ishii, H., Hashiguchi, K., Seki, M., Ide, M., Sugiyama, K., Ishimoto, H., Nakayama, S., Mukae, H., and Kohno, S. Interstitial pneumonia caused by inhalation of fumes of nickel and chrome. Respirology. 2006;11(6):814-817. PubMed
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Maitake Mushroom 8 references
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Ceylon Cinnamon 22 references
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Salacia 5 references
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Cordyceps 14 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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