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Dietary supplement

Jaundice Support Ingredients & Drug Interactions

by TerraVita

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Jaundice Support is a dietary supplement by TerraVita with 2 active ingredients. Its ingredients are commonly taken for digestive upset, antimicrobial support, blood sugar support.Based on those ingredients, 1,210 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Barberry Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Jaundice Support by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (0.13 mL) without saying how much of each component you get.

Jaundice Support contains 2 active ingredients in a proprietary blend: barberry glycerite liquid extract and centaury glycerite liquid extract. Both are plant extracts delivered in liquid form.

The product also contains glycerin as an inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Jaundice support.
  • We looked for evidence on: Liver function, Biliary disorders, Hyperbilirubinemia.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence we hold shows insufficient reliable evidence to rate barberry for acne, bacterial vaginosis, breast cancer, dental plaque, or diabetes. For centaury, we have insufficient reliable evidence to rate it for diabetic kidney disease (diabetic nephropathy).

Because the manufacturer makes no specific effectiveness claim on this product label, and our data don't establish proven benefit for any particular use, you'll want to talk with your doctor or pharmacist about what this product is intended to address in your case.

The evidence, ingredient by ingredient European Barberry Centaury

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Barberry is generally used in small amounts as a digestive bitter, but quality evidence on safe long-term use is limited — it may be okay in the short term for some people. The most serious concern is a documented case of severe liver injury and blood-related complications (hepatitis-associated aplastic anemia) in an adult after 2 weeks of European barberry at 15 drops twice daily combined with another herb.

The patient developed lethargy, loss of appetite, and jaundice that progressed to high fevers, severe infection risk, and abnormal liver function. Centaury is also used in small amounts traditionally, but high-quality safety data are limited.

Neither ingredient should be used during pregnancy or while breastfeeding — barberry may cross the placenta and enter breast milk with potential harm to a newborn or nursing infant, and centaury safety in pregnancy and lactation is unknown.

Side effects, ingredient by ingredient European Barberry Centaury

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — European Barberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,211 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Jaundice Support, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin or aspirin), blood pressure medications, diabetes drugs, sleep aids or sedatives, anticholinergic drugs (like some bladder or allergy medications), cholinergic drugs, or any drug processed by the liver's CYP3A4 enzyme — a large group that includes many heart, immune, and psychiatric medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Jaundice Support is best avoided if you take blood thinners, blood pressure medications, diabetes drugs, or medications processed through your liver. The documented risk of liver injury is a red flag, especially with long-term use.

If you're pregnant or breastfeeding, this product is not appropriate. Talk with your doctor or pharmacist before starting it — they know your full medication list and can tell you whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Jaundice Support, straight from the product label.

Brand TerraVita
Barcode (UPC) 064435236014
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 282065
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Jaundice Support by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064435236014
IngredientAmount% DV
Proprietary Blend0.13 mL--
Barberry Glycerite Liquid Extract0 NP--
Centaury Glycerite Liquid Extract0 NP--

Other ingredients: Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Glycerite liquid extract (1:5)

Formulation

Alcohol free

No flavor

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

See for yourself

Jaundice Support by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Jaundice Support by TerraVita

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

0.13 mL per serving

Other (inactive) ingredients: Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Jaundice Support by TerraVita Drug Interactions

Want to check YOUR meds against Jaundice Support?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,210Drugs
1,210 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Jaundice Support with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Barberry Glycerite Liquid Extract8 drug types · 1,210 drugs

Anticholinergic Drugs

Theoretically, taking European barberry with anticholinergic drugs might cause additive effects.
In vitro evidence suggests that European barberry might have anticholinergic properties.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, European barberry may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal evidence suggest that berberine, a constituent of European barberry, might inhibit platelet aggregation. Theoretically, European barberry might have a similar effect.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking European barberry with antidiabetes drugs might increase the risk of hypoglycemia.
Preliminary clinical evidence suggests that European barberry juice reduces fasting glucose levels in patients with type 2 diabetes who are also taking antidiabetes drugs. Additionally, some animal studies show that berberine, a constituent of European barberry, has antiglycemic potential. Monitor blood glucose levels closely.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking European barberry with antihypertensive drugs might increase the risk of hypotension.
Animal and human research suggests that European barberry extracts can have hypotensive effects.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, taking European barberry with cholinergic drugs might decrease the effects of cholinergic drugs.
In vitro evidence suggests that European barberry might have anticholinergic properties.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, concomitant use with drugs that have sedative properties may cause additive effects.
Animal research suggests that berberine, a constituent of European barberry, might have sedative effects. Theoretically, European barberry might have a similar effect.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, concomitant use with cyclosporine may cause additive effects.
Berberine, a constituent of European barberry, can reduce the metabolism and increase serum levels of cyclosporine. This effect is attributed to the ability of berberine to inhibit cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine. Theoretically, European barberry might have a similar effect.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, European barberry might increase the levels and clinical effects of CYP3A4 substrates.
There is very preliminary evidence suggesting that berberine, a constituent of European barberry, might inhibit the CYP3A4 enzyme. Theoretically, European barberry might have a similar effect.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Jaundice Support, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Jaundice Support by TerraVita: Common Questions

Does Jaundice Support by TerraVita interact with any medications?
Yes. Based on its ingredients, Jaundice Support has a known interaction with 1,210 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Jaundice Support contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. The barberry in this product may cross the placenta and enter breast milk, with potential harm to a newborn or nursing infant. Centaury safety in pregnancy and breastfeeding is unknown. Avoid this product during pregnancy and while breastfeeding.
What are the side effects of Jaundice Support?
A documented case reports severe complications — hepatitis-associated aplastic anemia with liver injury — after 2 weeks of barberry at this product's strength, combined with another herb. The patient developed lethargy, loss of appetite, jaundice, high fevers, and life-threatening blood and infection problems requiring hospitalization. While serious adverse effects are rare, they can occur.
How long is it safe to take this product?
Quality evidence on safe long-term use of barberry is limited. It may be okay short-term for some people, but we don't have good data beyond that. Talk with your doctor or pharmacist about how long you should use it.
Does this product actually work for jaundice or diabetes?
The evidence we hold shows insufficient reliable evidence to rate barberry for diabetes or the other conditions the product suggests. We don't have proof it works for jaundice. Your doctor or pharmacist is the best person to discuss whether it's appropriate for your situation.
What is centaury used for in this blend?
Centaury is traditionally used as a digestive bitter, usually in small amounts. We have insufficient evidence to rate it for any specific condition, and high-quality safety data are limited.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Jaundice Support label
Sources

Sources & How We Checked

Jaundice Support's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

European Barberry 15 references
  1. Chan E. Displacement of bilirubin from albumin by berberine. Biol Neonate 1993;63:201-8. PubMed
  2. Wu X, Li Q, Xin H, Yu A, Zhong M. Effects of berberine on the blood concentration of cyclosporin A in renal transplanted recipients: clinical and pharmacokinetic study. Eur J Clin Pharmacol 2005;61:567-72. PubMed
  3. Shamsa F, Ahmadiani A, Khosrokhavar R. Antihistaminic and anticholinergic activity of barberry fruit (Berberis vulgaris) in the guinea-pig ileum. J Ethnopharmacol 1999;64:161-6. PubMed
  4. Fatehi M, Saleh TM, Fatehi-Hassanabad Z, et al. A pharmacological study on Berberis vulgaris fruit extract. J Ethnopharmacol 2005;102:46-52. PubMed
  5. Kostalova, D., Bukovsky, M., Koscova, H., and Kardosova, A. [Anticomplement activity of Mahonia aquifolium bisbenzylisoquinoline alkaloids and berberine extract]. Ceska.Slov.Farm 2001;50(6):286-289.
  6. Fatehi-Hassanabad, Z., Jafarzadeh, M., Tarhini, A., and Fatehi, M. The antihypertensive and vasodilator effects of aqueous extract from Berberis vulgaris fruit on hypertensive rats. Phytother Res 2005;19(3):222-225.
  7. Singh, J. and Kakkar, P. Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats. J Ethnopharmacol. 5-4-2009;123(1):22-26. PubMed
  8. Shanbhag, S. M., Kulkarni, H. J., and Gaitonde, B. B. Pharmacological actions of berberine on the central nervous system. Jpn.J Pharmacol 1970;20(4):482-487. PubMed
  9. Wu, J. F. and Liu, T. P. [Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion]. Yao Xue.Xue.Bao. 1995;30(2):98-102.
  10. Xuan, B., Wang, W., and Li, D. X. Inhibitory effect of tetrahydroberberine on platelet aggregation and thrombosis. Zhongguo Yao Li Xue.Bao. 1994;15(2):133-135.
  11. Gao, C. R., Zhang, J. Q., and Huang, Q. L. [Experimental study on berberin raised insulin sensitivity in insulin resistance rat models]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1997;17(3):162-164. DOI
  12. Sabir M and Bhide NK. Study of some pharmacological actions of berberine. Ind J Physiol & Pharmac 1971;15(3):111-132.
  13. Tripathi YB and Shukla SD. Berberis artistata inhibits PAF induced aggregation of rabbit platelets. Phytotherapy Research 1996;10:628-630.
  14. Lazavi F, Mirmiran P, Sohrab G, Nikpayam O, Angoorani P, Hedayati M. The barberry juice effects on metabolic factors and oxidative stress in patients with type 2 diabetes: A randomized clinical trial. Complement Ther Clin Pract. 2018;31:170-174. PubMed
  15. Philips CA, Theruvath AH, Ravindran R. Toxic hepatitis-associated aplastic anaemia after dual homeopathic remedies and Gymnema sylvestre use. BMJ Case Rep 2022;15(3):e247867. PubMed

See these in context on the European Barberry monograph →

Centaury 1 reference
  1. Martynyuk L, Martynyuk L, Ruzhitska O, Martynyuk O. Effect of the herbal combination Canephron N on diabetic nephropathy in patients with diabetes mellitus: results of a comparative cohort study. J Altern Complement Med. 2014;20(6):472-478. PubMed

See these in context on the Centaury monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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