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Dietary supplement

Job's Tears Ingredients & Drug Interactions

by Herbal Terra

Job's Tears label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Job's Tears against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Job's Tears is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for digestive support, skin health and smoothness, mild swelling or water retention.Based on those ingredients, 128 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Job's Tears (Coix lacryma-jobi) dried grains liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Job's Tears by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with Job's Tears by Herbal Terra — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Job's Tears by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: certified organic Job's Tears (Coix lacryma-jobi) as a dried grains liquid extract. Job's tears is a grain traditionally used in herbal medicine.

The only other ingredient listed is menstruum, which is the liquid used to create the extract.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Job's Tears product and its label doesn't state a use — see Job's Tears's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold insufficient reliable evidence to rate Job's tears for lowering cholesterol or managing high cholesterol (hyperlipidemia). The data we have isn't robust enough to say whether it works for that purpose.

If you're considering it for cholesterol, talk with your doctor about whether the evidence supports its use for your situation.

The evidence, ingredient by ingredient Job's Tears

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Job's tears is generally well tolerated as a cooked food, but concentrated supplement evidence is limited. Adverse effects in trials aren't documented in our data.

Safety data in lactation is not on file. The product is traditionally avoided during pregnancy, and human safety data for pregnancy are lacking — so if you're pregnant or planning to be, talk with your doctor or pharmacist before using it.

For general use, stick to ordinary food amounts and check with a clinician if you have concerns.

Side effects, ingredient by ingredient Job's Tears

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Job's Tears.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 128 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take antidiabetes drugs (insulin, glimepiride, glyburide, pioglitazone, rosiglitazone), theophylline, dextromethorphan cough suppressants, chlorzoxazone muscle relaxers, or diltiazem heart medication before starting this product. All are rated Moderate severity for interaction with Job's tears.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Job's Tears may be worth considering if you're interested in traditional herbal grains, but the effectiveness evidence for cholesterol isn't established. If you take diabetes medications, heart drugs, or cough suppressants, you'll need to check your specific medications with your pharmacist first because of potential interactions.

Pregnant people should avoid it. Always run your prescriptions through our interaction tool on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Job's Tears, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7429524017074
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 233756
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Job's Tears by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
7429524017074
IngredientAmount% DV
certified organic Job's Tears (Coix lacryma-jobi) dried grains liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Origin of plant material: Nepal.

Manufactured in the USA in an FDA registered facility

Sugar free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Coix lacryma-jobi

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Job's Tears by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Job's Tears label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Job's Tears by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Certified organic Job's Tears (Coix lacryma-jobi) dried grains liquid extract

Interacts with
128 drugs
970 mg per serving

Job's Tears is a grain-like seed long used as a food and in traditional medicine, especially in East Asia. While it is generally safe as a food and is...

Certified organic Job's Tears (Coix lacryma-jobi) dried grains liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Job's Tears by Herbal Terra Drug Interactions

Want to check YOUR meds against Job's Tears?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
128Drugs
128 Moderate

Ingredients driving the most interactions

certified organic Job's Tears (Coix lacryma-jobi) dried grains liquid extract 128

Individual Drug Interactions

The ingredients in Job's Tears interact with 128 drugs. Click any drug to see the details.

1 of the 1 ingredient in Job's Tears interact with drugs. Each result below shows which ingredient is responsible. certified organic Job's Tears (Coix lacryma-jobi) dried grains liquid extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Job's Tears with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Job's Tears (Coix lacryma-jobi) dried grains liquid extract5 drug types · 128 drugs

Antidiabetes Drugs

Preliminary evidence shows that constituents of Job's tears might have hypoglycemic effects. Theoretically, concomitant use with drugs that decrease blood glucose levels might increase the risk of hypoglycemia. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Likelihood Possible Evidence D
Chlorzoxazone (Parafon Forte, Paraflex)

Animal research suggests that Job's tears might enhance absorption of chlorzoxazone in the small intestine. Single dose and short-term oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing chlorzoxazone increases chlorzoxazone peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.

Likelihood Possible Evidence D
Dextromethorphan (Robitussin Dm, Others)

Animal research suggests that Job's tears might enhance absorption of dextromethorphan in the small intestine. Single dose oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing dextromethorphan increases dextromethorphan area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Animal research suggests that Job's tears might enhance absorption of diltiazem in the small intestine. Single dose oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing diltiazem increases diltiazem peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.

Likelihood Possible Evidence D
Theophylline

Animal research suggests that Job's tears might enhance absorption of theophylline in the small intestine. Single dose and short-term oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing theophylline increases theophylline peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.

Likelihood Possible Evidence D
certified organic Job's Tears (Coix lacryma-jobi) dried grains liquid extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Job's Tears, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

Job's Tears by Herbal Terra: Common Questions

Does Job's Tears by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Job's Tears has a known interaction with 128 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Job's Tears contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Job's Tears safe to use if I'm pregnant?
No. Job's tears is traditionally avoided in pregnancy and human safety data are lacking. If you're pregnant or planning to be, talk with your doctor or pharmacist before using it.
Can I take Job's Tears if I'm breastfeeding?
We don't have reliable data on safety during lactation. Talk with your pharmacist or doctor for personalized advice.
Does this product actually work for cholesterol?
We don't have enough reliable evidence to say whether Job's tears lowers cholesterol. If that's what you're considering it for, discuss other options with your doctor.
What is Job's Tears?
Job's tears (Coix lacryma-jobi) is a grain used in traditional herbal medicine. This product is a concentrated liquid extract of the dried grains.
Are there any documented side effects?
We don't have adverse effects documented in our trial data. That said, the concentrated supplement evidence is limited — most safety experience comes from eating it as a cooked food.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Job's Tears is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Job's Tears label
Go deeper

The Full Monographs Behind Job's Tears’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Job's Tears

Interacts with 128 drugs

Job's Tears is a grain-like seed long used as a food and in traditional medicine, especially in East Asia. While it is generally safe as a food and is being studied for possible effects on m...

Read the full Job's Tears monograph →
Sources

Sources & How We Checked

Job's Tears's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Job's Tears 3 references
  1. Chiang W, Cheng C, Chiang M, Chung KT. Effects of dehulled adlay on the culture count of some microbiota and their metabolism in the gastrointestinal tract of rats. J Agric Food Chem 2000;48:829-32. PubMed
  2. Yu YM, Chang WC, Liu CS, Tsai CM. Effect of young barley leaf extract and adlay on plasma lipids and LDL oxidation in hyperlipidemic smokers. Biol Pharm Bull 2004;27:802-5. PubMed
  3. Yao HT, Lin JH, Liu YT, Li ML, Chiang W. Food-Drug Interaction between the Adlay Bran Oil and Drugs in Rats. Nutrients 2019;11(10):2473. PubMed

See these in context on the Job's Tears monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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