Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

Jocko Super Krill Ingredients & Drug Interactions

by Jocko Fuel

Jocko Super Krill label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Jocko Super Krill against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Jocko Super Krill is a dietary supplement by Jocko Fuel with 5 active ingredients. Its ingredients are commonly taken for heart and cholesterol support, high triglycerides, joint pain and inflammation.Based on those ingredients, 838 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Esterified Astaxanthin, Krill Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Jocko Super Krill by Jocko Fuel

Ask about any prescription or over-the-counter medication and we check it for interactions with Jocko Super Krill by Jocko Fuel — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Jocko Super Krill by Jocko Fuel

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “Total Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (300 mg) without saying how much of each component you get.

Jocko Super Krill contains 5 ingredients: krill oil, eicosapentaenoic acid, docosahexaenoic acid, total omega-3 fatty acids, phospholipids, and esterified astaxanthin. The main actives are krill oil—a marine source of omega-3 fatty acids—and astaxanthin, a carotenoid antioxidant also found in certain seafood.

There are no inactive fillers listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

  • Dry eye via Krill Oil Possibly Effective
Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Dry eye — rated "Possibly Effective" (Krill Oil) (Natural Medicines).

Krill oil is possibly effective for dry eye. For other conditions—aging skin, Alzheimer disease, cancer, high cholesterol, and cognitive function—the evidence is insufficient to rate it.

Astaxanthin similarly lacks reliable evidence for age-related cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome. Neither ingredient's effectiveness is established in our data for most of the claims you might see.

The evidence, ingredient by ingredient Krill Oil Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Krill oil is generally well tolerated in doses up to 4 grams daily. Common side effects include bloating, decreased appetite, diarrhea, fishy burps, flatulence, heartburn, nausea, and stomach discomfort.

These tend to be less frequent or severe than with fish oil alone. Headache, tiredness, and dizziness have been reported rarely.

Avoid krill oil if you have a shellfish allergy and use caution if you have a bleeding disorder. Astaxanthin is also generally well tolerated, though long-term safety data are limited.

Reported side effects include abdominal pain, diarrhea, and red fecal color. Higher doses (40 mg daily) have caused severe stomach pain in a small number of cases.

For pregnancy, the safety data are insufficient for both krill oil and astaxanthin—talk with your doctor or pharmacist before using either during pregnancy or while breastfeeding.

Side effects, ingredient by ingredient Krill Oil Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Astaxanthin, Krill Oil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 839 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (the krill oil may raise bleeding risk), diabetes medications (krill oil might lower blood sugar further), or drugs broken down by CYP3A4 or CYP2B6 enzymes in your liver (astaxanthin may slow their clearance). Altogether, these interactions span 839 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines krill oil and astaxanthin to target dry eye and general wellness. If you take blood thinners, diabetes medications, or drugs metabolized by your liver's CYP3A4 or CYP2B6 enzymes, check with your doctor or pharmacist before starting it—the interactions are documented but not yet proven in humans, and the risk may still matter to you.

Expect possible digestive side effects like fishy burps and stomach discomfort. Talk it over with your doctor or pharmacist, especially if you're pregnant, breastfeeding, or have a bleeding disorder.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Jocko Super Krill, straight from the product label.

Brand Jocko Fuel
Barcode (UPC) 708088781056
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 232545
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Jocko Super Krill by Jocko Fuel, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
708088781056
IngredientAmount% DV
Calories10 Calorie(s)--
Krill Oil1000 mg--
Calories from Fat10 Calorie(s)--
Total Fat1 Gram(s)1%
Eicosapentaenoic Acid120 mg--
Docosahexaenoic Acid80 mg--
Cholesterol3 mg2%
Total Omega-3 Fatty Acids300 mg--
Saturated Fat0.5 Gram(s)4%
Phospholipids200 mg--
Esterified Astaxanthin200 mcg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

If you are pregnant, lactating or under any medical supervision or on any medication, consult a physician before using this or any dietary supplement

Warning: Contains shellfish

Formulation

Made in America

Formula

Krill oil 500mg

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Jocko Super Krill by Jocko Fuel label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Jocko Super Krill label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Jocko Super Krill by Jocko Fuel

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Krill Oil

Interacts with
208 drugs
1000 mg per serving

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglyce...

Krill Oil monograph & interactions

Total Omega-3 Fatty Acids

300 mg per serving
  • › Eicosapentaenoic Acid
  • › Docosahexaenoic Acid

Phospholipids

200 mg per serving

Esterified Astaxanthin

Interacts with
671 drugs
200 mcg per serving

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Esterified Astaxanthin monograph & interactions
Interaction report

Jocko Super Krill by Jocko Fuel Drug Interactions

Want to check YOUR meds against Jocko Super Krill?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
838Drugs
838 Moderate

Ingredients driving the most interactions

Esterified Astaxanthin 671
Krill Oil 208

Individual Drug Interactions

The ingredients in Jocko Super Krill interact with 838 drugs. Click any drug to see the details.

2 of the 5 ingredients in Jocko Super Krill interact with drugs. Each result below shows which ingredient is responsible. Esterified Astaxanthin Krill Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Jocko Super Krill with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Esterified Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Esterified Astaxanthin full monograph & interactions

Krill Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Taking high doses of omega-3 fatty acids from fish oil can modestly decrease platelet aggregation. Since krill oil also contains these fatty acids, taking high doses of krill oil might also inhibit platelet aggregation. Theoretically, taking high doses of krill oil with antiplatelet or anticoagulant drugs might increase the risk of bleeding. However, the omega-3 content of krill oil is much lower than that of fish oil.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking krill oil with antidiabetes drugs might increase the risk of hypoglycemia.
Some research in animals and humans shows that krill oil might lower blood glucose levels. However, a small study shows that taking krill oil does not reduce blood glucose levels in patients with type 2 diabetes, most of whom were taking antidiabetes drugs.

Likelihood Possible Evidence B
Krill Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Jocko Super Krill, from the product label.

Jocko Fuel

See all Jocko Fuel products
Name
Origin Labs, LLC
Phone Number
1-888-858-1416
Web Address
www.OriginMaine.com
Pharmacist Counseling Corner

Jocko Super Krill by Jocko Fuel: Common Questions

Does Jocko Super Krill by Jocko Fuel interact with any medications?
Yes. Based on its ingredients, Jocko Super Krill has a known interaction with 838 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Jocko Super Krill contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this product interfere with my blood thinner?
Possibly. Krill oil may increase your bleeding risk if combined with anticoagulant or antiplatelet drugs by slowing how your blood clots. Talk to your doctor or pharmacist before adding this product—they can weigh the benefit against the risk based on your dose and your specific medication.
Can I take this if I'm taking diabetes medication?
Check with your doctor or pharmacist first. Krill oil might lower blood sugar in some people, which could strengthen your medication's effect and raise the risk of low blood sugar. One small study found no blood-sugar reduction, so the effect isn't certain—but it's worth monitoring.
What are the most common side effects?
Bloating, decreased appetite, diarrhea, fishy burps, flatulence, heartburn, nausea, and stomach discomfort are the most common, usually from the krill oil. These tend to be milder with krill oil than with fish oil. Rare side effects include headache, tiredness, and dizziness.
Is this safe during pregnancy or breastfeeding?
There isn't enough reliable safety data for either krill oil or astaxanthin during pregnancy or breastfeeding. Talk with your doctor or pharmacist before using this product if you're pregnant or breastfeeding—they can advise you based on your individual situation.
Does this product have a shellfish allergy warning?
Yes. Krill is a shellfish-like crustacean, so avoid this product if you have a shellfish allergy. Also use caution if you have a bleeding disorder.
Is krill oil actually better than fish oil?
Krill oil does contain omega-3 fatty acids like fish oil, but research on its effectiveness is incomplete. It is possibly effective for dry eye. For most other uses—aging skin, cognitive function, high cholesterol—evidence is insufficient to rate it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Jocko Super Krill label
Go deeper

The Full Monographs Behind Jocko Super Krill’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Krill Oil

Interacts with 208 drugs

Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglycerides and supporting heart health, but t...

Read the full Krill Oil monograph → Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Jocko Super Krill's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Krill Oil 13 references
  1. Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
  2. Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
  3. Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
  4. Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev 2004;9:420-8.
  5. Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-9.
  6. Harris WS, Miller M, Tighe AP, et al. Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives. Atherosclerosis 2008;197:12-24. PubMed
  7. Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic steatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. J Agric Food Chem 10-14-2009;57:9339-45. PubMed
  8. Maki, K. C., Reeves, M. S., Farmer, M., Griinari, M., Berge, K., Vik, H., Hubacher, R., and Rains, T. M. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr.R PubMed
  9. Albert BB, Derraik JG, Brennan CM, et al. Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men. Am J Clin Nutr 2015;102(1):49-57.
  10. Berge K, Musa-Veloso K, Harwood M, Hoem N, Burri L. Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutr Res 2014;34(2):126-33. PubMed
  11. Lobraico JM, DiLello LC, Butler AD, Cordisco ME, Petrini JR, Ahmadi R. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Res Care. 2015 PubMed
  12. van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
  13. van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed

See these in context on the Krill Oil monograph →

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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