Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Kids' Immune Protect Ingredients & Drug Interactions

by Planetary Herbals

Kids' Immune Protect label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Kids' Immune Protect against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Kids' Immune Protect is a dietary supplement by Planetary Herbals with 3 active ingredients. Its ingredients are commonly taken for immune support, colds and flu, upper respiratory infections.Based on those ingredients, 975 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bai-Zhu Atractylodes, Astragalus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Kids' Immune Protect by Planetary Herbals

Ask about any prescription or over-the-counter medication and we check it for interactions with Kids' Immune Protect by Planetary Herbals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Kids' Immune Protect by Planetary Herbals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (1 mL) without saying how much of each component you get.

Kids' Immune Protect is a liquid with 3 active ingredients: a proprietary extract blend (whose specific components aren't individually listed on the label), astragalus, and bai-zhu atractylodes—all herbs traditionally used to support immune function. The inactive ingredients are glycerin, purified water, and natural orange flavor.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Supports immune defenses for children.
  • We looked for evidence on: Common cold, Influenza, Upper respiratory tract infection (URTI), immune function, respiratory health, seasonal wellness.
  • The closest evidence on file: Astragalus is rated "Insufficient Reliable Evidence To Rate" for Upper respiratory tract infection (URTI) (Natural Medicines).
  • Also on file: Atractylodes is rated "Insufficient Reliable Evidence To Rate" for Common cold, Influenza.

The product facts provide no effectiveness ratings for Kids' Immune Protect itself. Both astragalus and bai-zhu atractylodes have been studied for various uses—hay fever, asthma, anemia, appetite, digestion, and colds among them—but the evidence is insufficient to establish they work for any of these.

Because we don't hold a breakdown for the proprietary blend, we can't assess its active components separately.

The evidence, ingredient by ingredient Astragalus Atractylodes

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astragalus is generally well tolerated in the short term for healthy adults, but human safety data are limited. A small number of trial participants reported dizziness and palpitations, though these effects may not have been caused by the herb itself.

Bai-zhu atractylodes is used traditionally but has limited safety research; adverse effects reported in small studies include allergic reactions, dry mouth, and nausea. The safety data advises against astragalus during pregnancy and while breastfeeding.

For bai-zhu atractylodes, the data shows it is possibly unsafe in pregnancy; safety during breastfeeding is unknown, so it's best avoided then as well.

Side effects, ingredient by ingredient Astragalus Atractylodes

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Astragalus, Atractylodes.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 976 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before giving this product, double-check with your child's doctor or pharmacist if they take immunosuppressants or cyclophosphamide (moderate risk that astragalus may interfere), lithium (moderate risk of raised levels), diabetes medications (moderate risk of low blood sugar), blood thinners or antiplatelet drugs like warfarin or aspirin (moderate risk of increased bleeding), aromatase inhibitors for cancer (moderate risk of additive effects), or hexobarbital (moderate risk of prolonged sedation). Minor interactions may also occur with medications metabolized through certain liver pathways.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines two immune-supporting herbs with a track record in traditional medicine but limited human safety research. If your child takes any prescription medication—especially immune suppressants, lithium, diabetes drugs, blood thinners, or cancer medications—check with your child's doctor or pharmacist before starting.

The same goes if you're pregnant or breastfeeding; talk it over with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Kids' Immune Protect, straight from the product label.

Brand Planetary Herbals
Barcode (UPC) 021078105435
Net contents 2 fl. Oz.; 59.14 mL
Market status On market
Date entered into DSLD Jul 25, 2017
DSLD ID 76686
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Kids' Immune Protect by Planetary Herbals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.4286 mL
Maximum serving Sizes:
1 mL
Servings per container
59
UPC/BARCODE
021078105435
IngredientAmount% DV
Proprietary Extract Blend1 mL--
Astragalus0 NP--
Siler0 NP--
Bai-Zhu Atractylodes0 NP--

Other ingredients: Glycerin, purified Water, natural Orange flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Non-alcoholic

General Statements

Supports immune defenses

Formulated by Michael Tierra L.Ac, O.M.D

FDA Statement of Identity

Herbal Supplement

Formula

Kids' Immune Protect helps boost resistance at the start of winter and is especially helpful for back-to-school challenges.

Suggested/Recommended/Usage/Directions

Suggested Use: For children 1-5 years, 15 drops twice daily between meals. For children 5 years and older, 35 drops twice daily between meals.

Precautions

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if tamper-evident seal is broken or missing.

Keep out of the reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

PF0543 REV L161-B

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Kids' Immune Protect by Planetary Herbals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Kids' Immune Protect label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Kids' Immune Protect by Planetary Herbals

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.4286 mL Dosage formLiquid Servings per container59 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Extract Blend

1 mL per serving

Other (inactive) ingredients: Glycerin, Purified Water, Natural Orange flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Kids' Immune Protect by Planetary Herbals Drug Interactions

Want to check YOUR meds against Kids' Immune Protect?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
975Drugs
333 Moderate 642 Minor

Ingredients driving the most interactions

Bai-Zhu Atractylodes 801
Astragalus 208

Individual Drug Interactions

The ingredients in Kids' Immune Protect interact with 975 drugs. Click any drug to see the details.

2 of the 3 ingredients in Kids' Immune Protect interact with drugs. Each result below shows which ingredient is responsible. Bai-Zhu Atractylodes Astragalus

Each ingredient & the kinds of drugs it affects

For each ingredient in Kids' Immune Protect with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bai-Zhu Atractylodes5 drug types · 801 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Laboratory research suggests that atractylenolides II and III, constituents of atractylodes, reduce platelet activation. So far, this has not been shown in humans.

Likelihood Possible Evidence D
Aromatase Inhibitors

Theoretically, atractylodes may have an additive effect when used with other aromatase inhibitors.
Laboratory research suggests that atractylodes and its constituents exhibit aromatase inhibitor effects.

Likelihood Possible Evidence D
Hexobarbital

Theoretically, taking atractylodes may prolong the therapeutic and adverse effects of hexobarbital.
In animals, atractylodes has been shown to prolong the effects of hexobarbital. These effects have not been shown in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
In animals, atractylodes administered at high doses has been shown to induce CYP1A2 activity. This effect has not been shown in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
In animals, atractylodes administered at high doses has been shown to inhibit CYP3A1 activity, which is a homolog to the human CYP3A4 enzyme. This effect has not been shown in humans.

Likelihood Possible Evidence D
Bai-Zhu Atractylodes full monograph & interactions

Astragalus4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
Astragalus full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Kids' Immune Protect, from the product label.

Planetary Herbals

See all Planetary Herbals products
Name
Planetary Herbals, LLC
Street Address
P.O. Box 1760
City
Soquel
State
CA
ZipCode
95073
Web Address
www.planetaryherbals.com
Pharmacist Counseling Corner

Kids' Immune Protect by Planetary Herbals: Common Questions

Does Kids' Immune Protect by Planetary Herbals interact with any medications?
Yes. Based on its ingredients, Kids' Immune Protect has a known interaction with 975 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Kids' Immune Protect contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy or while breastfeeding?
No. The safety data advises against astragalus during pregnancy and breastfeeding. Bai-zhu atractylodes is possibly unsafe in pregnancy and its safety while breastfeeding is unknown. Talk with your doctor or pharmacist before use if you're pregnant, planning to become pregnant, or breastfeeding.
What are the side effects I should watch for?
Astragalus has been associated with dizziness and palpitations in small studies, though it's not clear the herb caused them. Bai-zhu atractylodes may cause allergic reactions, dry mouth, or nausea. Overall, these ingredients are generally well tolerated, but human safety data are limited.
Does this actually work to boost immunity?
The evidence isn't established. Both astragalus and bai-zhu atractylodes have been studied for various immune and health uses, but we don't have reliable evidence that either works for any specific condition.
What is astragalus used for?
Astragalus is a traditional immune-supporting herb that has been studied for hay fever, asthma, anemia, appetite, and colds, but the evidence so far is insufficient to confirm it works for any of these.
Can I use this with my child's other medicines?
That depends on what they're taking. This product interacts with a number of medications—particularly immune suppressants, lithium, diabetes drugs, and blood thinners. Use the medication checker on this page with your child's exact medications, and confirm with their doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Kids' Immune Protect label
Go deeper

The Full Monographs Behind Kids' Immune Protect’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astragalus

Interacts with 208 drugs

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...

Read the full Astragalus monograph → Herb & supplement monograph

Atractylodes

Interacts with 801 drugs

Atractylodes is a root used for centuries in traditional Chinese, Japanese, and Thai medicine, mostly for digestive complaints and fatigue, often as part of multi-herb formulas. Modern resea...

Read the full Atractylodes monograph →
Sources

Sources & How We Checked

Kids' Immune Protect's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astragalus 13 references
  1. Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
  2. Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
  3. Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
  4. Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
  5. Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
  6. Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
  7. Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
  8. Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
  9. Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
  10. Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
  11. Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
  12. Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
  13. Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):

See these in context on the Astragalus monograph →

Atractylodes 6 references
  1. Liu Y, Jia Z, Dong L, et al. A randomized pilot study of atractylenolide I on gastric cancer cachexia patients. Evid Based Complement Alternat Med 2008;5:337-44. PubMed
  2. Chen Y, Yang W, Guo L, Wu X, Zhang T, Liu J, Zhang J. Atractylodes lactone compounds inhibit platelet activation. Platelets. 2017 Mar;28(2):194-202. PubMed
  3. Jiang H, Shi J, Li Y. Screening for compounds with aromatase inhibiting activities from Atractylodes macrocephala Koidz. Molecules. 2011 Apr 14;16(4):3146-51. PubMed
  4. Koonrungsesomboon N, Na-Bangchang K, Karbwang J. Therapeutic potential and pharmacological activities of Atractylodes lancea (Thunb.) DC. Asian Pac J Trop Med. 2014 Jun;7(6):421-8. PubMed
  5. Li L, Tang LY, Man GC, Yeung BH, Lau CB, Leung PC, Wang CC. Potential reproductive toxicity of Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage. Hum Reprod. 2011 Dec;26(12):3280-8. PubMed
  6. Muhamad N, Plengsuriyakarn T, Na-Bangchang K. Atractylodes lancea for cholangiocarcinoma: Modulatory effects on CYP1A2 and CYP3A1 and pharmacokinetics in rats and biodistribution in mice. PLoS One 2022;17(11):e0277614. PubMed

See these in context on the Atractylodes monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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