Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Klean Joint & Muscle Ingredients & Drug Interactions

by Klean Athlete

Klean Joint & Muscle label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Klean Joint & Muscle against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Klean Joint & Muscle is a dietary supplement by Klean Athlete with 3 active ingredients. Its ingredients are commonly taken for muscle soreness after exercise, gout and joint discomfort, sleep support.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are AstaReal. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Klean Joint & Muscle by Klean Athlete

Ask about any prescription or over-the-counter medication and we check it for interactions with Klean Joint & Muscle by Klean Athlete — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Klean Joint & Muscle by Klean Athlete

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Klean Joint & Muscle contains three active ingredients. VitaCherry is a concentrated sour cherry extract, TamaFlex (which we have no data on), and AstaReal, a form of astaxanthin, a carotenoid compound with antioxidant properties.

The product also includes inactive ingredients like hydroxypropylmethylcellulose and microcrystalline cellulose to form and stabilize the capsules.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Joint and muscle recovery support.
  • We looked for evidence on: Exercise-induced muscle soreness, Exercise-induced muscle damage, Gout, Osteoarthritis, Rheumatoid arthritis (RA), Aromatase inhibitor-induced arthralgia — and 3 related terms.
  • The closest evidence on file: Sour Cherry is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness (Natural Medicines).
  • Also on file: Sour Cherry is rated "Insufficient Reliable Evidence To Rate" for Osteoarthritis, Gout, Aromatase inhibitor-induced arthralgia.
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness, Osteoarthritis, Rheumatoid arthritis (RA).

The evidence for what this product can do is thin. VitaCherry has possibly effective evidence for athletic performance, but insufficient evidence for exercise-induced muscle soreness, ADHD, cognitive function, exercise-induced respiratory infections, and fibromyalgia.

Astaxanthin shows insufficient evidence across several uses including athletic performance, cognitive decline, macular degeneration, and carpal tunnel syndrome. We have no effectiveness data on file for TamaFlex.

The evidence, ingredient by ingredient Sour Cherry Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

VitaCherry is likely safe in pregnancy and lactation. It's generally well tolerated as a whole fruit, though concentrated supplements like this one are less studied—common side effects in trials include abdominal pain, loose stools, and gastrointestinal upset.

Astaxanthin is generally well tolerated in short-term studies, but long-term safety data are limited. The safety data advise against astaxanthin during pregnancy and while breastfeeding.

Orally, astaxanthin may cause abdominal pain, diarrhea, or red-colored stools; higher doses have caused severe stomach pain in some cases.

Side effects, ingredient by ingredient Sour Cherry Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Klean Joint & Muscle, double-check with your pharmacist or doctor if you take any drugs metabolized by the liver enzyme CYP3A4 (Moderate severity), such as heart medications, statins, blood pressure drugs, or immunosuppressants. Also confirm any medications broken down by CYP2B6 (Moderate severity).

Astaxanthin may reduce how quickly your body clears these drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with athletic performance based on its cherry content, though the evidence is modest. If you take any regular medications—especially those that your liver processes—you'll want to check with your pharmacist or doctor before starting, because astaxanthin may lower their effectiveness.

Pregnant or breastfeeding? The astaxanthin in here isn't recommended; talk it over with your doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Klean Joint & Muscle, straight from the product label.

Brand Klean Athlete
Barcode (UPC) 310539979792
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Feb 23, 2022
DSLD ID 259897
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Klean Joint & Muscle by Klean Athlete, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetarian Capsule(s)
Maximum serving Sizes:
2 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
310539979792
IngredientAmount% DV
VitaCherry480 mg--
TamaFlex400 mg--
AstaReal4 mg--

Other ingredients: Hydroxypropylmethylcellulose, Microcrystalline Cellulose, Ascorbyl Palmitate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Nutritional Supplements

Gluten-free, Non-GMO

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

NSF Certified Sport

Suggested/Recommended/Usage/Directions

Suggested usage: As a dietary supplement, adults take 2 capsules daily, or as directed by a trainer, coach, or health professional.

Precautions

Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health professional before using this product.

Keep out of the reach of children.

Use only if safety seal is intact.

Brand IP Statement(s)

TamaFlex is a trademark of NXT USA, Inc. Patents Pending VitaCherry is a registered trademark of VCF Futureceuticals, Inc., used under license. AstaReal is a registered trademark of Fuji Chemical Industries Co., Ltd.

Storage

Store in a cool, dry place.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our Klean manufacturing and certifications

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Klean Joint & Muscle by Klean Athlete label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Klean Joint & Muscle label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Klean Joint & Muscle by Klean Athlete

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

VitaCherry

No known
interactions
480 mg per serving Form: Tart Cherry

Sour cherry (often sold as tart cherry or Montmorency cherry) is a fruit-based supplement rich in antioxidants that people use for muscle recovery, jo...

VitaCherry monograph & interactions

TamaFlex

400 mg per serving Form: Tamarind (Tamarindus indicus) seed extract, Turmeric (Curcuma longa) rhizome extract

AstaReal

Interacts with
671 drugs
4 mg per serving Form: Astaxanthin

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

AstaReal monograph & interactions

Other (inactive) ingredients: Hydroxypropylmethylcellulose, Microcrystalline Cellulose, Ascorbyl Palmitate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Klean Joint & Muscle by Klean Athlete Drug Interactions

Want to check YOUR meds against Klean Joint & Muscle?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

AstaReal 671

Individual Drug Interactions

The ingredients in Klean Joint & Muscle interact with 671 drugs. Click any drug to see the details.

1 of the 3 ingredients in Klean Joint & Muscle interact with drugs. Each result below shows which ingredient is responsible. AstaReal

Each ingredient & the kinds of drugs it affects

For each ingredient in Klean Joint & Muscle with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

AstaReal2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
AstaReal full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Klean Joint & Muscle, from the product label.

Klean Athlete

See all Klean Athlete products
Name
Klean Athlete
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Phone Number
1.855.255.5326
Web Address
www.kleanathlete.com
Pharmacist Counseling Corner

Klean Joint & Muscle by Klean Athlete: Common Questions

Does Klean Joint & Muscle by Klean Athlete interact with any medications?
Yes. Based on its ingredients, Klean Joint & Muscle has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Klean Joint & Muscle contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The sour cherry in this product (VitaCherry) is likely safe in pregnancy and lactation. However, astaxanthin should be avoided during pregnancy and breastfeeding because there isn't enough safety data. Talk with your doctor or pharmacist about what's right for you.
Will this help with sore muscles after a workout?
The sour cherry extract has possibly effective evidence for athletic performance in general, but there's insufficient evidence specifically for exercise-induced muscle soreness. Astaxanthin doesn't have enough evidence for this use either.
What are the most common side effects?
The sour cherry can cause abdominal pain, loose stools, and gastrointestinal upset in some people. Astaxanthin may cause similar issues—abdominal pain, diarrhea, or red-colored stools—especially at higher doses.
Is astaxanthin the red coloring in the product?
Astaxanthin is a carotenoid with antioxidant properties that happens to be red in color, but it's in here for its supplement effects, not just as a colorant.
What is TamaFlex for?
TamaFlex is one of the three active ingredients, but we have no data on file about what it does or how it works. Your product label or the manufacturer may have more detail.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Klean Joint & Muscle is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Klean Joint & Muscle label
Go deeper

The Full Monographs Behind Klean Joint & Muscle’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sour Cherry

Sour cherry (often sold as tart cherry or Montmorency cherry) is a fruit-based supplement rich in antioxidants that people use for muscle recovery, joint and gout symptoms, and sleep. Early...

Read the full Sour Cherry monograph → Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Klean Joint & Muscle's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sour Cherry 4 references
  1. Schumacher HR, Pullman-Mooar S, Gupta SR, et al. Randomized double-blind crossover study of the efficacy of a tart cherry juice blend in treatment of osteoarthritis (OA) of the knee. Osteoarthritis Cartilage 2013;21(8):1035-41. PubMed
  2. Seymour EM, Warber SM, Kirakosyan A, et al. Anthocyanin pharmacokinetics and dose-dependent plasma antioxidant pharmacodynamics following whole tart cherry intake in healthy humans. J Funct Food 2014;11:509-16. DOI
  3. Elliot DL, Kuehl KS, Jones KD, Dulacki K. Using an eccentric exercise-testing protocol to assess the beneficial effects of tart cherry juice in fibromyalgia patients. Integ Med 2010;9(6):25-9.
  4. Soltanifar A, Moharreri F, Bakhtiari E, Hosseinpour A. The Effect of Adding Sour Cherry Concentrate to The Usual Treatment of Attention Deficit Hyperactivity Disorder In 6 To 12 Years Old Children. J Atten Disord 2023;27(2):214-219. PubMed

See these in context on the Sour Cherry monograph →

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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