Klean Probiotic Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Klean Probiotic against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Klean Probiotic is a dietary supplement by Klean Athlete with 10 active ingredients. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,080 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm, Lactobacillus acidophilus (La-14), Bifidobacterium longum (Bl-05). Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Klean Probiotic by Klean Athlete
Ask about any prescription or over-the-counter medication and we check it for interactions with Klean Probiotic by Klean Athlete — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Klean Probiotic by Klean Athlete
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Klean Probiotic contains 10 ingredients total, including live probiotic strains and botanical support. The active probiotics are Lactobacillus acidophilus (La-14), Lactobacillus rhamnosus (Lr-32), Lactobacillus gasseri (Lg-36), Bifidobacterium longum (Bl-05), Bifidobacterium lactis (HN019), Bifidobacterium bifidum/lactis (Bb-02), Lactococcus lactis (Ll-23), and Streptococcus thermophilus (St-21)—plus FOS and Slippery Elm to support digestive health.
The product also contains microcrystalline cellulose and a capsule as inactive ingredients.
Does it work?
Moderate evidence
The evidence for what this probiotic can do varies by strain and condition. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.
For most other conditions listed—allergic rhinitis, asthma, anxiety, athletic performance, and cognitive decline—the evidence for these probiotic strains isn't established in the data we hold. Slippery Elm's effectiveness for constipation, cough, diarrhea, and inflammatory bowel disease is also not yet established from reliable studies.
How safe is it?
Well-documented data
Lactobacillus acidophilus and Streptococcus thermophilus are generally well tolerated in healthy adults and children, though you should check with your doctor before use. Bifidobacterium longum and Lactobacillus gasseri are generally well tolerated in healthy people, but caution is advised for anyone who is seriously ill or immune-compromised.
Slippery Elm is generally well tolerated for short-term use, though high-quality safety data are limited. Common side effects from probiotics are usually mild—epigastric discomfort, abdominal pain, gas, bloating, and diarrhea—and happen rarely.
Allergic reactions including rash, itching, and contact dermatitis have been reported with slippery elm.
Meds to double-check
Moderate interaction found
Before starting Klean Probiotic, double-check with your doctor or pharmacist if you take any oral medications—Slippery Elm may slow their absorption. Antibiotics are especially important to discuss: all four probiotic strains we checked interact with them, and you'll want to space them apart.
Since these probiotics contain live organisms, taking them together with antibiotics could reduce how well the probiotic works.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Klean Probiotic is a multi-strain probiotic aimed at digestive and immune support, with the strongest evidence for irritable bowel syndrome and antibiotic-associated diarrhea. Before you start it, check with your doctor or pharmacist if you're taking any oral medications or antibiotics—especially antibiotics, which shouldn't be taken at the same time as these probiotics.
It's generally well tolerated in healthy people, but if you're seriously ill, immune-compromised, or pregnant or breastfeeding, talk with your healthcare provider first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Klean Probiotic, straight from the product label.
| Brand | Klean Athlete |
|---|---|
| Barcode (UPC) | 310539038390 |
| Net contents | 60 Vegetarian Acid-Resistant Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2020 |
| DSLD ID | 232695 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Klean Probiotic by Klean Athlete, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| FOS | 0 NP | -- |
| Slippery Elm | 0 NP | -- |
| Lactococcus lactis (Ll-23) | 0 NP | -- |
| Digestive and Prebiotic Blend | 210 mg | -- |
| Multi-Strain Probiotic Blend | 0 NP | -- |
| Lactobacillus acidophilus (La-14) | 0 NP | -- |
| Lactobacillus rhamnosus (Lr-32) | 0 NP | -- |
| Bifidobacterium lactis (HN019) | 0 NP | -- |
| Bifidobacterium longum (Bl-05) | 0 NP | -- |
| Bifidobacterium bifidum/lactis (Bb-02) | 0 NP | -- |
| Lactobacillus gasseri (Lg-36) | 0 NP | -- |
| Streptococcus thermophilus (St-21) | 0 NP | -- |
Other ingredients: Microcrystalline Cellulose, Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Nutritional supplements
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our Klean manufacturing and certifications
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
NSF Certified Sport
Formulation
Gluten-free, Non-GMO
Suggested/Recommended/Usage/Directions
Suggested Usage: As a dietary supplement, adults take 1 capsule 1-2 times daily or as directed by a trainer, coach, or health professional.
Precautions
Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.
Caution: If you are immunocompromised, consult your health professional before using probiotic-containing products.
Keep out of the reach of children.
Use only if safety seal is intact.
Storage
Store in a cool, dry place.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Klean Probiotic by Klean Athlete label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Klean Probiotic by Klean Athlete
These are the 10 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Vegetarian Acid-Resistant Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Digestive and Prebiotic Blend
- › FOS
- › Slippery Elm
Multi-Strain Probiotic Blend
- › Lactococcus lactis (Ll-23)
- › Lactobacillus acidophilus (La-14)
- › Lactobacillus rhamnosus (Lr-32)
- › Bifidobacterium lactis (HN019)
- › Bifidobacterium longum (Bl-05)
- › Bifidobacterium bifidum/lactis (Bb-02)
- › Lactobacillus gasseri (Lg-36)
- › Streptococcus thermophilus (St-21)
Other (inactive) ingredients: Microcrystalline Cellulose, Capsule. These complete the product’s ingredient list but are not active constituents.
Klean Probiotic by Klean Athlete Drug Interactions
HelloPharmacist Interaction Report
Klean Probiotic by Klean Athlete contains several live probiotic strains—Lactobacillus acidophilus, Bifidobacterium longum, Lactobacillus gasseri, and Slippery Elm—that interact with medications.
The most serious documented interaction is Moderate: Slippery Elm may slow how your body absorbs oral drugs and reduce their levels in your bloodstream. This happens because the mucilage in slippery elm can interfere with drug absorption in your digestive tract.
Read the full breakdown — every affected drug type, severity by severity
All three Lactobacillus strains (acidophilus, gasseri) and Bifidobacterium longum have a Moderate interaction with antibiotics. Since these probiotics contain live organisms, taking them at the same time as antibiotics might kill a significant number of the beneficial bacteria and reduce how well the probiotic works.
Separating when you take them is important.
We could not check FOS, Lactococcus lactis, Lactobacillus rhamnosus, Bifidobacterium lactis, or Bifidobacterium bifidum/lactis for interactions—we hold no data on them. Streptococcus thermophilus was checked and shows no interactions documented in our data.
Altogether, these interactions span 2,081 individual medications. Use the search tool on this page to check your exact medications before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Klean Probiotic?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Klean Probiotic interact with 2,080 drugs. Click any drug to see the details.
4 of the 10 ingredients in Klean Probiotic interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm Lactobacillus acidophilus (La-14) Bifidobacterium longum (Bl-05) Lactobacillus gasseri (Lg-36)
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Klean Probiotic — through 1 ingredient. Tap an ingredient for the detail:
Slippery ElmOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Klean Probiotic with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Slippery Elm
Oral Drugs
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.
Lactobacillus acidophilus (La-14)
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Bifidobacterium longum (Bl-05)
Antibiotic Drugs
Theoretically, taking Bifidobacterium longum with antibiotic drugs might decrease the effectiveness of B. longum.
Since B. longum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. longum preparations by at least 2 hours.
Lactobacillus gasseri (Lg-36)
Antibiotic Drugs
Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L. gasseri.
Lactobacillus gasseri preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. gasseri preparations by at least two hours.
Brand information
Manufacturer and brand details for Klean Probiotic, from the product label.
Klean Athlete
See all Klean Athlete products- Name
- Klean Athlete
- Street Address
- 600 Boyce Road
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15205
- Phone Number
- 1.855.255.5326
- Web Address
- www.kleanathlete.com
Klean Probiotic by Klean Athlete: Common Questions
Does Klean Probiotic by Klean Athlete interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What are the probiotics in this product meant to do?
Can I take this while I'm on antibiotics?
Are there side effects?
Is it safe to take while pregnant or breastfeeding?
Will this slow down how my other medications work?
What if I'm on a blood thinner or other serious medication?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Klean Probiotic is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Klean Probiotic’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Slippery Elm
Interacts with 2,022 drugsSlippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...
Read the full Slippery Elm monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph → Herb & supplement monographBifidobacterium Longum
Interacts with 182 drugsBifidobacterium longum is a 'friendly' bacterium found naturally in the human gut and used as a probiotic. It is generally well tolerated and is most studied for digestive issues, though evi...
Read the full Bifidobacterium Longum monograph → Herb & supplement monographLactobacillus Gasseri
Interacts with 182 drugsLactobacillus gasseri is a 'friendly' probiotic bacterium found naturally in the human gut, mouth, and vaginal tract, and in some fermented foods. Early research suggests it may help with di...
Read the full Lactobacillus Gasseri monograph → Herb & supplement monographStreptococcus Thermophilus
Streptococcus thermophilus is a friendly bacterium used as a probiotic, often combined with other strains in yogurt and supplements. It is generally well tolerated in healthy people and may...
Read the full Streptococcus Thermophilus monograph →Sources & How We Checked
Klean Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 72 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Slippery Elm 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
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See these in context on the Streptococcus Thermophilus monograph →
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