Major interaction on record — check this product against your medications before combining. Based on 1 of 4 ingredients. Check your meds →
Dietary supplement

Klean BCAA + Peak ATP Orange Flavor Ingredients & Drug Interactions

by Klean Athlete

Klean BCAA + Peak ATP Orange Flavor label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Klean BCAA + Peak ATP Orange Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Klean BCAA + Peak ATP Orange Flavor is a dietary supplement by Klean Athlete with 4 active ingredients. Its ingredients are commonly taken for energy and cellular function support, athletic performance and muscle energy, circulation support.Based on those ingredients, 47 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Peak ATP. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Klean BCAA + Peak ATP Orange Flavor by Klean Athlete

Ask about any prescription or over-the-counter medication and we check it for interactions with Klean BCAA + Peak ATP Orange Flavor by Klean Athlete — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Klean BCAA + Peak ATP Orange Flavor by Klean Athlete

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Klean BCAA + Peak ATP contains four active ingredients: three branched-chain amino acids — L-Valine, L-Leucine, and L-Isoleucine — and Peak ATP (a form of adenosine, a compound involved in energy production and heart function). The inactive ingredients are natural orange flavor, xylitol, citric acid, malic acid, rebaudioside A, sunflower lecithin, monk fruit extract, and annatto extract.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: athletic performance and muscle energy support.
  • We looked for evidence on: Athletic performance, muscle endurance, exercise recovery, workout performance.
  • The closest evidence on file: Adenosine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).

The effectiveness data we hold covers only adenosine (Peak ATP's monograph). Adenosine is rated as effective for paroxysmal supraventricular tachycardia (an abnormal heart rhythm) and for cardiovascular disease diagnosis.

The evidence for the branched-chain amino acids in this product is not established in the data we hold.

The evidence, ingredient by ingredient Adenosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The safety picture here is important: the data notes that oral adenosine supplement evidence is limited, and the prescription injectable form — much more powerful — must only be given by medical professionals. The facts state there isn't enough safety information for supplement use, so it's best avoided.

Safety has also not been established for breastfeeding, so it should be avoided while nursing. When given intravenously, the prescription form of adenosine can cause chest pain, dizziness, shortness of breath, facial flushing, headache, low blood pressure, nausea, nervousness, numbness, tingling, and arrhythmias (abnormal heart rhythms).

When taken by mouth or injection into muscle, no adverse effects have been reported, though a thorough safety evaluation hasn't been done.

Side effects, ingredient by ingredient Adenosine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Adenosine.
  • The most serious interaction on file is rated Major.
  • For scale: 47 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take dipyridamole (Persantine) — this is a Major interaction. If you take carbamazepine (Tegretol) for seizures, that's a Moderate concern.

Also flag any methylxanthines you're on: caffeine pills, aminophylline, or theophylline. If you're unsure about your medications, use the checker below to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is designed for active athletes, but it contains Peak ATP — an ingredient with significant interactions with heart and seizure medications, and a safety profile that's not well established in supplement form. If you take dipyridamole, carbamazepine, or any methylxanthine (including caffeine supplements), or if you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting this product.

For anyone else, it's worth a conversation with your healthcare provider to weigh whether the benefits make sense for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Klean BCAA + Peak ATP Orange Flavor, straight from the product label.

Brand Klean Athlete
Barcode (UPC) 310539977460
Net contents 9.1 Ounce(s); 258 Gram(s)
Market status On market
Date entered into DSLD Oct 24, 2023
DSLD ID 293246
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Klean BCAA + Peak ATP Orange Flavor by Klean Athlete, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
8.6 Gram(s)
Maximum serving Sizes:
8.6 Gram(s)
Servings per container
30
UPC/BARCODE
310539977460
IngredientAmount% DV
Calories35 Calorie(s)--
Sugar Alcohol1 Gram(s)--
Total Carbohydrate5 Gram(s)2%
L-Valine1 Gram(s)--
L-Leucine2 Gram(s)--
L-Isoleucine1 Gram(s)--
Peak ATP400 mg--

Other ingredients: natural Orange flavor, Xylitol, Citric Acid, Malic Acid, Rebaudioside A, Sunflower Lecithin, Monk Fruit Extract, Annatto extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Klean Athlete Nutritional Supplements

Peak ATP is a registered trademark of TSI USA Inc. and is used under license.

FDA Statement of Identity

Dietary Supplement

Formulation

Gluten-free, Non-Gmo

Suggested/Recommended/Usage/Directions

Suggested usage: As a dietary supplement, mix 1 scoop with 8-10 oz. of water or other beverage and blend well. This product is best taken 30 minutes before exercise. It can also be consumed during and post-workout. Consume 1-2 servings daily without food, including rest days or as directed by a trainer, coach, or health professional.

Precautions

Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health professional before using this product.

Keep out of the reach of children.

Not intended for animals. Use only if safety seal is intact.

Storage

Store in a cool, dry place.

General Statements

Package by weight not volume. Settling may occur. Scan to learn about our Klean manufacturing and certifications

Seals/Symbols

NSF Certified Sport

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Klean BCAA + Peak ATP Orange Flavor by Klean Athlete label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Klean BCAA + Peak ATP Orange Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Klean BCAA + Peak ATP Orange Flavor by Klean Athlete

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size8.6 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Valine

1 Gram(s) per serving

L-Leucine

2 Gram(s) per serving

L-Isoleucine

1 Gram(s) per serving

Peak ATP

Interacts with
47 drugs
400 mg per serving

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat...

Peak ATP monograph & interactions

Other (inactive) ingredients: Natural Orange flavor, Xylitol, Citric Acid, Malic Acid, Rebaudioside A, Sunflower Lecithin, Monk Fruit Extract, Annatto extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Klean BCAA + Peak ATP Orange Flavor by Klean Athlete Drug Interactions

Want to check YOUR meds against Klean BCAA + Peak ATP Orange Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
47Drugs
2 Major 1 Moderate 44 Minor

Ingredients driving the most interactions

Peak ATP 47

Individual Drug Interactions

The ingredients in Klean BCAA + Peak ATP Orange Flavor interact with 47 drugs. Click any drug to see the details.

1 of the 4 ingredients in Klean BCAA + Peak ATP Orange Flavor interact with drugs. Each result below shows which ingredient is responsible. Peak ATP

Each ingredient & the kinds of drugs it affects

For each ingredient in Klean BCAA + Peak ATP Orange Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Peak ATP3 drug types · 47 drugs

Dipyridamole (Persantine)

Dipyridamole can increase the therapeutic and toxic effects of adenosine.
Dipyridamole decreases the metabolism of adenosine. Intravenous infusion of adenosine in patients who are taking dipyridamole can cause dizziness, bradycardia, and syncope. Dipyridamole should be discontinued for several days prior to a cardiac stress test using adenosine.

Likelihood Likely Evidence D
Carbamazepine (Tegretol)

Carbamazepine might increase the risk of heart block when used concomitantly with adenosine.
Carbamazepine and adenosine can both cause heart block. Giving them concurrently might produce an additive effect.

Likelihood Possible Evidence D
Methylxanthines

Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.
The methylxanthines, aminophylline, caffeine, and theophylline, can block the effects of adenosine by acting as competitive antagonists at adenosine cell surface receptors. It is recommended that methylxanthines be avoided for 24 hours prior to cardiac stress tests.

Likelihood Possible Evidence D
Peak ATP full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Klean BCAA + Peak ATP Orange Flavor, from the product label.

Klean Athlete

See all Klean Athlete products
Name
Klean Athlete
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Phone Number
1.855.255.5326
Web Address
www.kleanathlete.com
Pharmacist Counseling Corner

Klean BCAA + Peak ATP Orange Flavor by Klean Athlete: Common Questions

Does Klean BCAA + Peak ATP Orange Flavor by Klean Athlete interact with any medications?
Yes. Based on its ingredients, Klean BCAA + Peak ATP Orange Flavor has a known interaction with 47 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Klean BCAA + Peak ATP Orange Flavor contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are the branched-chain amino acids (BCAAs) in this product?
The three BCAAs are L-Valine, L-Leucine, and L-Isoleucine. They're amino acids your body uses to build and repair muscle, especially during and after intense exercise. We don't have interaction data on file for these three, so they may be safer than the Peak ATP ingredient if you're on medications.
What is Peak ATP, and what does it do?
Peak ATP is adenosine, a compound your body makes naturally for energy production and heart function. In supplement form, it's used to support athletic performance and cardiovascular health. The evidence shows it's effective for certain heart rhythm abnormalities and heart testing, but the safety data for taking it by mouth as a supplement is limited.
Can I take this while pregnant or breastfeeding?
No — safety hasn't been established for breastfeeding, so it should be avoided while nursing. For pregnancy, the data available doesn't support taking this product. Talk with your doctor or midwife about what's right for your situation.
What adverse effects might I experience?
When adenosine is given as a prescription injection into a vein, it can cause chest pain, dizziness, shortness of breath, headache, low blood pressure, and heart rhythm problems. Taken by mouth in supplement form, no adverse effects have been formally reported, though a complete safety study hasn't been done.
Does caffeine interfere with this product?
Yes — caffeine and related compounds (aminophylline, theophylline) block Peak ATP's effects in your body. If you take any caffeine supplement or these medications, avoid them for 24 hours before using this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Klean BCAA + Peak ATP Orange Flavor is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Klean BCAA + Peak ATP Orange Flavor label
Go deeper

The Full Monographs Behind Klean BCAA + Peak ATP Orange Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Adenosine

Interacts with 47 drugs

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat certain fast heart rhythms. As an over-t...

Read the full Adenosine monograph →
Sources

Sources & How We Checked

Klean BCAA + Peak ATP Orange Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Adenosine 10 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Agteresch HJ, Dagnelie PC, van den Berg JW, Wilson JH. Adenosine triphosphate: established and potential clinical applications. Drugs 1999;58:211-32.. PubMed
  3. Agteresch HJ, Dagnelie PC, van der Gaast A, et al. Randomized clinical trial of adenosine 5'-triphosphate in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 2000;92:321-8.. PubMed
  4. Haskell CM, Wong M, Williams A, Lee LY. Phase I trial of extracellular adenosine 5'-triphosphate in patients with advanced cancer. Med Pediatr Oncol 1996;27:165-73.. DOI
  5. Haskell CM, Mendoza E, Pisters KM, et al. Phase II study of intravenous adenosine 5'-triphosphate in patients with previously untreated stage IIIB and stage IV non-small cell lung cancer. Invest New Drugs 1998;16:81-5.. PubMed
  6. Eisenach JC, Curry R, Hood DD. Dose response of intrathecal adenosine in experimental pain and allodynia. Anesthesiology 2002;97:938-42.. PubMed
  7. Agteresch HJ, Dagnelie PC, Rietveld T, et al. Pharmacokinetics of intravenous ATP in cancer patients. Eur J Clin Pharmacol 2000;56:49-55.. PubMed
  8. Underwood DA. Which medications should be held before a pharmacologic or exercise stress test? Cleve Clin J Med 2002;69:449-50. PubMed
  9. Litmann L, Anderson JD, Monroe MH. Adenosine and Aggrenox: A hazardous combination. Ann Intern Med 2002;137:E-76. PubMed
  10. Faghihi G, Iraji F, Rajaee Harandi M, et al. Comparison of the efficacy of topical minoxidil 5% and adenosine 0.75% solutions on male androgenic alopecia and measuring patient satisfaction rate. Acta Dermatovenerol Croat 2013;21(3):155-9.

See these in context on the Adenosine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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