L-Ergothioneine 5 mg Ingredients & Drug Interactions
by SuperSmart
What is this page for?
First and foremost: checking L-Ergothioneine 5 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
L-Ergothioneine 5 mg is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, healthy aging and longevity, cellular protection.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of L-Ergothioneine 5 mg by SuperSmart
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: L-ergothioneine, a compound found naturally in foods like mushrooms and certain grains. The capsule also includes acacia gum as an inactive ingredient (a binder).
Does it work?
Couldn't assess
The evidence we hold shows insufficient reliable data to rate L-ergothioneine for coronary heart disease or joint pain. That means we don't yet have enough high-quality trial information to say whether it works for those uses.
If you're considering it for a specific health goal, talk it over with your doctor or pharmacist to see what the broader research picture suggests.
How safe is it?
Some data gaps
L-Ergothioneine appears well tolerated in food sources and short-term studies, but long-term safety as a supplement hasn't been well established. The safety data advises against use during pregnancy and while breastfeeding, since supplement-dose safety hasn't been studied in those situations.
If you're pregnant, breastfeeding, or planning to become pregnant, talk with your doctor or pharmacist before taking this product.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredient we checked. Run your specific medications through the search tool on this page, and ask your doctor or pharmacist if you're uncertain.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.
L-Ergothioneine 5 mg is a single-ingredient supplement with no documented drug interactions in our data. Evidence for its effectiveness in coronary heart disease or joint pain is too thin to rate.
It's generally well tolerated, but long-term safety isn't established, and it should be avoided during pregnancy and breastfeeding. Check with your own doctor or pharmacist about whether it makes sense for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about L-Ergothioneine 5 mg, straight from the product label.
| Brand | SuperSmart |
|---|---|
| Barcode (UPC) | 5453003826347 |
| Net contents | 30 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 22, 2021 |
| DSLD ID | 250573 |
| Product type | Amino Acid/protein |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for L-Ergothioneine 5 mg by SuperSmart, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Recommended use: Adults. Take one capsule a day.
5 mg per day
Formula
Precautions: Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.
Precautions
Keep out of children's reach.
As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.
Storage
Store away from direct light, heat and humidity.
Formulation
Advanced antioxidant
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
L-Ergothioneine 5 mg by SuperSmart label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in L-Ergothioneine 5 mg by SuperSmart
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
L-Ergothioneine
No knowninteractions
Ergothioneine is a naturally occurring amino acid–like compound (an antioxidant) found mostly in mushrooms and made by certain fungi and bacteria. Ear...
L-Ergothioneine monograph & interactionsOther (inactive) ingredients: Acacia Gum. These complete the product’s ingredient list but are not active constituents.
L-Ergothioneine 5 mg by SuperSmart Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in L-Ergothioneine 5 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for L-Ergothioneine 5 mg, from the product label.
SuperSmart
See all SuperSmart products- Name
- SN Worldwide Unipessoal, Lda
- Street Address
- Avenida Do Infante 66, Edificio Quinta Avenida 1 C
- City
- Funchal
- ZipCode
- 9000-015
L-Ergothioneine 5 mg by SuperSmart: Common Questions
Does L-Ergothioneine 5 mg by SuperSmart interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm pregnant or breastfeeding?
Does L-ergothioneine actually work for heart health or joint pain?
Is this supplement safe to take long-term?
What is L-ergothioneine, and where does it come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if L-Ergothioneine 5 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind L-Ergothioneine 5 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
L-Ergothioneine 5 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 2 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Ergothioneine 2 references
- Benson KF, Ager DM, Landes B, Aruoma OI, Jensen GS. Improvement of joint range of motion (ROM) and reduction of chronic pain after consumption of an ergothioneine-containing nutritional supplement. Prev Med. 2012;54 Suppl:S83-9. PubMed
- Smith E, Ottosson F, Hellstrand S, et al. Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease. Heart 2019. pii: heartjnl-2019-315485. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC