No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

L-Proline 3000 mg Ingredients & Drug Interactions

by SuperSmart

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

L-Proline 3000 mg is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for joint and connective tissue support, skin health and wound healing, collagen production.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of L-Proline 3000 mg by SuperSmart

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: L-proline, an amino acid that your body uses to build and repair connective tissues like collagen. Each capsule delivers 3,000 mg.

The only inactive ingredient is acacia gum, used as a binder.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Proline's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports collagen production.
  • We looked for evidence on: Wound healing, skin health, connective tissue, joint support.
  • The closest evidence on file: Proline is rated "Insufficient Reliable Evidence To Rate" for Wound healing (Natural Medicines).

The evidence we hold on L-proline doesn't establish it as effective for athletic performance, bone health (osteoporosis, osteopenia, or fractures), or wound healing. Each of these uses carries a rating of insufficient reliable evidence to rate, meaning the research so far hasn't been solid enough to draw firm conclusions either way.

The evidence, ingredient by ingredient Proline

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-proline is generally considered low-risk when you eat it in food, but safety of supplement doses hasn't been well studied. We don't have enough reliable data on how safe extra amounts are, so your best bet is to stick with what a doctor recommends rather than self-dosing.

If you're breastfeeding, the safety of supplemental doses isn't established — talk with your doctor or pharmacist before taking this.

Side effects, ingredient by ingredient Proline

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.

L-Proline 3000 mg is a single-ingredient amino acid supplement with no documented medication interactions. Because the research on supplement doses is limited, it's wise to check with your doctor before starting, especially if you're pregnant, breastfeeding, or taking any other supplements.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about L-Proline 3000 mg, straight from the product label.

Brand SuperSmart
Barcode (UPC) 5453003822967
Net contents 180 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 315581
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for L-Proline 3000 mg by SuperSmart, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
UPC/BARCODE
5453003822967
IngredientAmount% DV
L-Proline3000 mg--

Other ingredients: Acacia Gum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Supports collagen production

FDA Statement of Identity

Dietary Supplement

Formula

L-Proline 3000 mg per day

Each vegetarian capsule contains 500 mg of L-proline.

Suggested/Recommended/Usage/Directions

Recommended Use: Adults. Take at least six vegetarian capsules per day (ie, 3 grams of L-proline) in two doses.

Precautions

Precautions: Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.

Keep out of children's reach.

As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.

Storage

Store away from direct light, heat and humidity.

See for yourself

L-Proline 3000 mg by SuperSmart label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in L-Proline 3000 mg by SuperSmart

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size6 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

L-Proline

No known
interactions
3000 mg per serving

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...

L-Proline monograph & interactions

Other (inactive) ingredients: Acacia Gum. These complete the product’s ingredient list but are not active constituents.

Interaction report

L-Proline 3000 mg by SuperSmart Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in L-Proline 3000 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for L-Proline 3000 mg, from the product label.

SuperSmart

See all SuperSmart products
Name
SN Worldwide Unipessoal, Lda
Street Address
Avenida Do Infante 66, Edificio Quinta Avenida 1 C
City
Funchal
ZipCode
9000-015
Pharmacist Counseling Corner

L-Proline 3000 mg by SuperSmart: Common Questions

Does L-Proline 3000 mg by SuperSmart interact with any medications?
We do not currently list a known interaction for the mapped ingredients in L-Proline 3000 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
L-Proline 3000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is L-proline safe to take while I'm breastfeeding?
The safety of supplemental doses while breastfeeding isn't established. We don't have enough data to say yes or no, so it's best to talk with your doctor or pharmacist for personalized advice before you start.
Does L-proline actually help with wound healing or bone health?
The evidence we have doesn't establish that it works for those purposes yet. The research so far has been insufficient to draw firm conclusions, so we can't say whether it'll help you.
What makes up the rest of the capsule if there's only one active ingredient?
The capsule also contains acacia gum, a plant-based binder that helps hold the ingredient together. That's the only other ingredient in the product.
Is L-proline safe to take if I'm pregnant?
The safety data doesn't cover supplemental doses in pregnancy, so there isn't enough information to know either way. It's important to talk with your doctor before taking any supplement during pregnancy.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if L-Proline 3000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

L-Proline 3000 mg label
Go deeper

The Full Monographs Behind L-Proline 3000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

L-Proline 3000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Proline 4 references
  1. Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
  2. Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
  3. Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
  4. Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed

See these in context on the Proline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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