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Dietary supplement

Larch Tree Arabinogalactan Ingredients & Drug Interactions

by Swanson

Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Larch Tree Arabinogalactan is a dietary supplement by Swanson with 1 active ingredient. Its ingredients are commonly taken for immune support, cold and flu prevention, digestive and gut health.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are ResistAid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Larch Tree Arabinogalactan by Swanson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: ResistAid (larch arabinogalactan), a fiber derived from the larch tree. The capsules also contain gelatin and magnesium stearate as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Larch Arabinogalactan's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: stimulates immune system and natural killer cells.
  • We looked for evidence on: Common cold, Immune function, Infection prevention, Respiratory infection.
  • The closest evidence on file: Larch Arabinogalactan is rated "Insufficient Reliable Evidence To Rate" for Common cold (Natural Medicines).

The evidence for larch arabinogalactan isn't yet established in the data we hold. It's been studied for the common cold and for high cholesterol, but the research so far is insufficient to rate it reliably for either use.

The evidence, ingredient by ingredient Larch Arabinogalactan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Larch arabinogalactan is generally well tolerated as a fiber, though some people experience bloating and flatulence. High-quality long-term safety data are limited.

We don't have enough safety information on this ingredient during pregnancy and lactation, so caution and guidance from your doctor are advised if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Larch Arabinogalactan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Larch Arabinogalactan.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take immunosuppressant medications—such as cyclosporine, tacrolimus, mycophenolate, or others used after transplant or for autoimmune conditions—check with your doctor or pharmacist before starting this product. Larch arabinogalactan may theoretically reduce how well these drugs work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement is an unproven fiber from larch bark. If you take any drug to suppress your immune system, you'll need to check with your doctor or pharmacist first—larch arabinogalactan may interfere with how those medications work.

Otherwise, it's generally well tolerated, though it can cause gas or bloating. Talk it over with your own healthcare provider to see if it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Larch Tree Arabinogalactan, straight from the product label.

Brand Swanson
Barcode (UPC) 087614020877
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 308639
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Larch Tree Arabinogalactan by Swanson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
087614020877
IngredientAmount% DV
ResistAid500 mg--

Other ingredients: Gelatin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Stimulates the body's immune system Enhances production of natural killer cells

Immune support

Formula

Glyconutrient

ResistAid

Larch Tree Arabinogalactan 500 mg per capsule

General Statements

Science-backed quality since 1969

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one capsule three times per day with water.

Brand IP Statement(s)

ResistAid is a trademark of Lonza.

Precautions

Warning: For adults only. Keep out of reach of children.

Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Do not use if seal is broken.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

See for yourself

Larch Tree Arabinogalactan by Swanson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Larch Tree Arabinogalactan by Swanson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

ResistAid

Interacts with
121 drugs
500 mg per serving Form: Arabinogalactan

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but...

ResistAid monograph & interactions

Other (inactive) ingredients: Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Larch Tree Arabinogalactan by Swanson Drug Interactions

Want to check YOUR meds against Larch Tree Arabinogalactan?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
121Drugs
121 Moderate

Ingredients driving the most interactions

ResistAid 121

Each ingredient & the kinds of drugs it affects

For each ingredient in Larch Tree Arabinogalactan with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

ResistAid1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Larch Tree Arabinogalactan, from the product label.

Swanson

See all Swanson products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
swanson.com
Pharmacist Counseling Corner

Larch Tree Arabinogalactan by Swanson: Common Questions

Does Larch Tree Arabinogalactan by Swanson interact with any medications?
Yes. Based on its ingredients, Larch Tree Arabinogalactan has a known interaction with 121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Larch Tree Arabinogalactan contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is larch arabinogalactan and what does it do?
It's a soluble fiber extracted from the larch tree. The data we have doesn't yet show it's reliably effective for any particular condition, though it's been studied for the common cold and high cholesterol.
Can this product cause side effects?
Most people tolerate it well, but some experience bloating and flatulence because it's a fiber. If you have a sensitive gut, start with a smaller dose.
Is it safe to take during pregnancy or breastfeeding?
We don't have enough safety data to know either way. Talk with your doctor or pharmacist about whether to use it while pregnant or breastfeeding—they can weigh your individual situation.
Will this interfere with my medications?
It has a documented interaction with immunosuppressant drugs used after transplant or for autoimmune conditions. Check with your doctor or pharmacist if you take any medication to suppress your immune system before starting this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Larch Tree Arabinogalactan is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Larch Tree Arabinogalactan label
Sources

Sources & How We Checked

Larch Tree Arabinogalactan's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Larch Arabinogalactan 8 references
  1. D'Adamo P. Larch arabinogalactan. J Naturopath Med 1996;6:33-7.
  2. Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
  3. Marett R, Slavin JL. No long-term benefits of supplementation with arabinogalactan on serum lipids and glucose. J Am Diet Assoc 2004;104:636-9.
  4. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 2001;20:279-85. PubMed
  5. Udani JK, Singh BB, Barrett ML, Singh VJ. Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers. Nutr J 2010;9:32. PubMed
  6. Grube B, Stier H, Riede L, Gruenwald J. Tolerability of a proprietary larch arabinogalactan extract: a randomized, double-blind, placebo-controlled clinical trial in healthy subjects. Food Nutr Sci 2012;3:1533-8. DOI
  7. Dion C, Chappuis E, Ripoll C. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutr Metab (Lond) 2016;13:28. PubMed
  8. Riede L, Grube B, Gruenwald J. Larch arabinogalactan effects on reducing incidence of upper respiratory tract infections. Curr Med Res Opin 2013;29(3):251-8.

See these in context on the Larch Arabinogalactan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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