No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 12 ingredients. Check your meds →
Dietary supplement

Lipazyme Ingredients & Drug Interactions

by Energique

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Lipazyme is a dietary supplement by Energique with 12 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Lipazyme by Energique

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 12 active ingredients.

Lipazyme is a blend of 12 digestive enzymes designed to support the breakdown of different foods. It contains lipase (fat digestion), lactase (dairy digestion), amylase (starch digestion), proteases like acid protease, neutral protease, and alkaline protease (protein digestion), plus cellulase, peptidase, invertase, diastase, pectinase, and a hemicellulase/phytase/beta-glucanase blend to handle plant fibers and other carbohydrates.

There are no other inactive ingredients listed.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Plant-based enzyme formula for digestive support.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Indigestion, Bloating.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

The evidence for most of these enzymes isn't established in our data. Lactase, the enzyme that breaks down dairy sugar (lactose), is rated effective for lactose intolerance — so if you have trouble digesting milk products, this ingredient may help.

For lipase (fat digestion) and the rest of the blend, we don't have enough reliable evidence to say whether they work for indigestion or other digestive complaints.

The evidence, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase and lactase are generally well tolerated when used as directed. The protease enzymes (acid protease, neutral protease, and alkaline protease) are also generally well tolerated in most adults, though rarely they can cause digestive upset or allergic reactions — the same enzymes used in some laundry products have triggered allergies in occupational settings.

If you have a serious digestive condition, use this product only under medical guidance. There is limited pregnancy and breastfeeding safety data for most ingredients in this blend; talk with your doctor or pharmacist before regular use if you're pregnant or nursing.

Side effects, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. However, we were unable to verify several of the enzymes in this product, so use the medication search tool on this page to confirm your specific medications.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Lipazyme is a multi-enzyme digestive formula that may help with lactose digestion, though the evidence for the other enzymes isn't clear from our data. It's generally well tolerated, but if you have a serious digestive condition or are pregnant or breastfeeding, check with your doctor or pharmacist before starting.

Run your medications through the tool below to make sure nothing clashes.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lipazyme, straight from the product label.

Brand Energique
Net contents 90 Cap(s)
Market status On market
Date entered into DSLD Aug 23, 2019
DSLD ID 205994
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lipazyme by Energique, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0 Not Present
Maximum serving Sizes:
0 Not Present
IngredientAmount% DV
Amylase0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Peptidase0 NP--
Invertase0 NP--
Diastase0 NP--
Pectinase0 NP--
Acid Protease0 NP--
Neutral Protease0 NP--
Alkaline Protease0 NP--
Hemicellulase/Phytase/Beta-Glucanase Blend0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Natural remedies from the Heartland

Plant-based enzyme formula

Suggested/Recommended/Usage/Directions

Please read all label information on delivery.

See for yourself

Lipazyme by Energique label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Lipazyme by Energique

These are the 12 active ingredients this product is made of. Select any to open its full monograph.

Serving size0 Not Present Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Amylase

0 NP per serving

Lipase

No known
interactions
0 NP per serving

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipase monograph & interactions

Lactase

No known
interactions
0 NP per serving

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...

Lactase monograph & interactions

Cellulase

0 NP per serving

Peptidase

0 NP per serving

Invertase

0 NP per serving

Diastase

0 NP per serving Form: Malt

Pectinase

0 NP per serving

Acid Protease

No known
interactions
0 NP per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Acid Protease monograph & interactions

Neutral Protease

No known
interactions
0 NP per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Neutral Protease monograph & interactions

Alkaline Protease

No known
interactions
0 NP per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Alkaline Protease monograph & interactions

Hemicellulase/Phytase/Beta-Glucanase Blend

0 NP per serving
Interaction report

Lipazyme by Energique Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lipazyme. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lipazyme, from the product label.

Energique

See all Energique products
Name
Energique
Pharmacist Counseling Corner

Lipazyme by Energique: Common Questions

Does Lipazyme by Energique interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lipazyme. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lipazyme contains 12 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lactase in this product help with lactose intolerance?
Yes — lactase is rated effective for lactose intolerance. If you have trouble digesting dairy, this ingredient is likely to help.
Can I take Lipazyme while pregnant?
Lactase is rated likely safe in pregnancy, but the safety data for the other enzymes in this blend is limited or not established. Talk with your doctor or pharmacist before starting, especially if you're using it regularly.
What are the proteases in this product for?
The three protease enzymes — acid protease, neutral protease, and alkaline protease — are meant to help break down proteins during digestion.
Is there a risk of allergic reactions to Lipazyme?
The protease enzymes in particular can rarely cause allergic reactions in sensitive people, though this is uncommon. If you have a known enzyme allergy or develop rash, swelling, or breathing trouble after taking it, stop and contact your doctor right away.
Can I take this if I have a digestive condition like IBS or Crohn's disease?
If you have a serious digestive condition, use this product only under medical guidance. Check with your doctor before starting.
Is it safe to breastfeed while taking Lipazyme?
Lactase has limited data but acts only in your gut, so it's likely low-risk. For the other enzymes, we don't have enough safety data. Ask your doctor or pharmacist before using this product regularly while breastfeeding.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lipazyme is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lipazyme label
Sources

Sources & How We Checked

Lipazyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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