Liposomal CoQ10 PQQ 5 mg Ingredients & Drug Interactions
by NuMedica
What is this page for?
First and foremost: checking Liposomal CoQ10 PQQ 5 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Liposomal CoQ10 PQQ 5 mg is a dietary supplement by NuMedica with 6 active ingredients. Its ingredients are commonly taken for high cholesterol, liver health, brain and memory support.Based on those ingredients, 986 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Resveratrol, Coenzyme Q-10, L-Carnitine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Liposomal CoQ10 PQQ 5 mg by NuMedica
Ask about any prescription or over-the-counter medication and we check it for interactions with Liposomal CoQ10 PQQ 5 mg by NuMedica — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Liposomal CoQ10 PQQ 5 mg by NuMedica
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
This liquid contains 6 active ingredients. Coenzyme Q10 is an antioxidant your cells use for energy production.
L-carnitine helps your body transport fatty acids for fuel. Resveratrol is a polyphenol from plants.
Lecithin is a phospholipid that aids cell function. BioPQQ is a pyrroloquinoline quinone compound.
Glycerin is a humectant (draws moisture in). The product also contains inactive ingredients: purified water, medium chain triglyceride, natural flavors, xanthan gum, gum arabic, stevia leaf extract, and potassium sorbate.
Does it work?
Strong evidence
CoQ10 is likely effective for CoQ10 deficiency and possibly effective for fibromyalgia, migraine, heart failure, and diabetic nerve damage. L-carnitine is effective for L-carnitine deficiency and possibly effective for high cholesterol, heart failure, and angina.
Resveratrol is possibly effective for obesity and hay fever, but possibly ineffective for heart disease and high cholesterol. Lecithin shows insufficient reliable evidence for most conditions it's studied for — it's likely ineffective for Alzheimer disease.
Glycerin is likely effective for constipation. We hold no effectiveness data for BioPQQ.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated; gastrointestinal side effects such as appetite loss, diarrhea, heartburn, and nausea occur in less than 1% of users. Headache, dizziness, and insomnia have been reported rarely, as have skin itching and allergic rash.
L-carnitine is generally well tolerated at typical doses but can cause stomach upset and a fish-like body odor at higher doses; seizures are rare. Lecithin is generally safe in food and supplement amounts but can cause abdominal pain, diarrhea, nausea, and allergic skin reactions in people with egg or soy allergies.
Resveratrol may cause diarrhea and gastrointestinal discomfort at higher doses. Glycerin is well tolerated but can cause bloating, diarrhea, nausea, and headache in large oral doses.
Pregnancy and lactation data: Lecithin and resveratrol are likely safe; coenzyme Q10 has no rating on file, and L-carnitine and glycerin have no pregnancy/lactation data on file — talk with your doctor or pharmacist about these if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Check with your pharmacist before starting if you take warfarin or other blood thinners — Coenzyme Q10 may reduce warfarin's effect while L-carnitine may increase it. If you take thyroid hormone replacement, L-carnitine may reduce its effectiveness.
If you take antiplatelet drugs like aspirin or other medications metabolized by your liver (CYP3A4, CYP2C19, CYP1A2, or CYP2E1 pathways), flag this product — resveratrol may interfere. No interactions are documented for the ingredients we could check in the chemotherapy or antihypertensive categories, though CoQ10 has theoretical concerns there.
The bottom line
Scorecard at a glancePartially disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
This product may help with energy production, heart health, and migraine if those are your concerns — but it's crucial to check it against your medications first, especially blood thinners, thyroid drugs, and anything your liver heavily metabolizes. If you're on warfarin or take thyroid hormone, talk to your pharmacist before starting.
If you have an egg or soy allergy, the lecithin here is a potential concern.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Liposomal CoQ10 PQQ 5 mg, straight from the product label.
| Brand | NuMedica |
|---|---|
| Barcode (UPC) | 812527015098 |
| Net contents | 6 Fluid Ounce(s); 180 mL |
| Market status | On market |
| Date entered into DSLD | Feb 23, 2025 |
| DSLD ID | 323552 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Liposomal CoQ10 PQQ 5 mg by NuMedica, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 200 mg | -- |
| Lecithin | 0 NP | -- |
| Coenzyme Q-10 | 100 mg | -- |
| L-Carnitine | 25 mg | -- |
| Resveratrol | 10 mg | -- |
| BioPQQ | 5 mg | -- |
| Glycerin | 0 NP | -- |
Other ingredients: Water, Purified, Medium Chain Triglyceride, Natural Flavors, Xanthan Gum, Gum Arabic, Stevia Leaf Extract, Potassium Sorbate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
NuMedica Advancing Nutrition
BioPQQ is a registered trademark of Mitsubishi Gas Chemical Company, Inc. Enhanced Absorption Technologies
Formulation
Professional Quality Formulas Enhanced absorption technologies
Does not contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.
GF Gluten-Free
Vegetarian Vegan
Formula
5mg of PQQ per serving
Proprietary Liposomal delivery system utilizing a specialized phosphatidylcholine complex with a unique ratio of PC, PE and oleic acid.
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Suggested/Recommended/Usage/Directions
Directions: Take about 1 teaspoon (6 mL) once per day or as directed by your healthcare practitioner. Shake well before use.
Precautions
Caution: Keep out of reach of children.
If pregnant, nursing or under the age of 18, please consult your healthcare practitioner.
If pregnant, nursing or under the age of 18, please consult your healthcare practitioner.
Storage
Storage: Store at room temperature. Refrigerate for best taste. Use within 45 days of opening.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Liposomal CoQ10 PQQ 5 mg by NuMedica label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Liposomal CoQ10 PQQ 5 mg by NuMedica
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size6 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Coenzyme Q-10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Coenzyme Q-10 monograph & interactionsL-Carnitine
Interacts with19 drugs
L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most...
L-Carnitine monograph & interactionsResveratrol
Interacts with822 drugs
Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While...
Resveratrol monograph & interactionsBioPQQ
Other (inactive) ingredients: Water, Purified, Medium Chain Triglyceride, Natural Flavors, Xanthan Gum, Gum Arabic, Stevia Leaf Extract, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.
Liposomal CoQ10 PQQ 5 mg by NuMedica Drug Interactions
HelloPharmacist Interaction Report
NuMedica's Liposomal CoQ10 PQQ does interact with several medication types, and the most serious concerns involve blood thinners.
Coenzyme Q10 in this product may reduce the effectiveness of warfarin (a blood thinner), and L-carnitine may increase warfarin's effects — so if you take warfarin, you'll want to flag this product with your doctor or pharmacist before starting. L-carnitine also interacts with thyroid hormone replacement, potentially reducing how well it works for your condition.
Read the full breakdown — every affected drug type, severity by severity
Resveratrol in the blend may theoretically increase levels of drugs your liver metabolizes, including certain antidepressants, some cancer medications, and other common prescriptions — though human studies are limited. It may also raise bleeding risk if you're on blood thinners or antiplatelet drugs like aspirin.
Coenzyme Q10 might theoretically reduce the activity of certain chemotherapy drugs and could lower blood pressure additively with blood pressure medications.
We could not check BioPQQ, as we hold no data for it. Altogether, these interactions span 975 individual medications.
Check your exact prescriptions with the search tool below before you start this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Liposomal CoQ10 PQQ 5 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Liposomal CoQ10 PQQ 5 mg interact with 986 drugs. Click any drug to see the details.
3 of the 6 ingredients in Liposomal CoQ10 PQQ 5 mg interact with drugs. Each result below shows which ingredient is responsible. Resveratrol Coenzyme Q-10 L-Carnitine
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Resveratrol + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Resveratrol + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Liposomal CoQ10 PQQ 5 mg — through 2 ingredients. Tap an ingredient for the detail:
ResveratrolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Resveratrol + Acenocoumarol interactionL-carnitineAcenocoumarol (sintrom) Moderate
Interaction Summary
Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
Read the full L-carnitine + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolAnticoagulant/antiplatelet Drugs, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Resveratrol + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Liposomal CoQ10 PQQ 5 mg — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Liposomal CoQ10 PQQ 5 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Resveratrol
Anticoagulant/Antiplatelet Drugs
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Resveratrol seems to have antiplatelet effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that resveratrol can inhibit CYP1A2 enzymes. However, this interaction has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Resveratrol might increase levels of drugs metabolized by CYP2E1.
In vitro research suggests that resveratrol inhibits CYP2E1 isoenzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that resveratrol can inhibit the CYP3A4 enzyme. However, clinical research shows that taking resveratrol 3000 mg daily for 8 weeks does not necessitate dose adjustments to medications metabolized by CYP3A4.
Coenzyme Q-10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
L-Carnitine
Acenocoumarol (Sintrom)
Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.
Thyroid Hormone
Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.
Warfarin (Coumadin)
Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.
Brand information
Manufacturer and brand details for Liposomal CoQ10 PQQ 5 mg, from the product label.
NuMedica
See all NuMedica products- Name
- NuMedica LLC
- Street Address
- 9503 E. 55th Place
- City
- Tulsa
- State
- OK
- ZipCode
- 74145
- Phone Number
- 800.869.8100
- Web Address
- www.numedica.com
Liposomal CoQ10 PQQ 5 mg by NuMedica: Common Questions
Does Liposomal CoQ10 PQQ 5 mg by NuMedica interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on warfarin or another blood thinner?
What if I take thyroid medication?
Will this give me side effects?
Is this safe during pregnancy or breastfeeding?
Does CoQ10 actually work for heart health?
What's BioPQQ and will it interact with my medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Liposomal CoQ10 PQQ 5 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lecithin
Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting most of its health claims is limited, t...
Read the full Lecithin monograph → Herb & supplement monographGlycerol
Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well established as a laxative and a skin and eye moi...
Read the full Glycerol monograph → Herb & supplement monographCoenzyme Q10
Interacts with 198 drugsCoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated and is most studied for heart condition...
Read the full Coenzyme Q10 monograph → Herb & supplement monographL-carnitine
Interacts with 19 drugsL-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...
Read the full L-carnitine monograph → Herb & supplement monographResveratrol
Interacts with 822 drugsResveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While lab and animal studies are promising, s...
Read the full Resveratrol monograph →Sources & How We Checked
Liposomal CoQ10 PQQ 5 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 122 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lecithin 9 references
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- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
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- Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
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- Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
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- Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
- Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:
Coenzyme Q10 40 references
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- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
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- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
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- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
- Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
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- Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
- Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed
L-carnitine 41 references
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- Anon. Carnitor (levocarnitine) package insert. Sigma-Tau Pharmaceuticals Inc, Gaithersburg, MD. December 1999.
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- Plioplys AV, Plioplys S. Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome. Neuropsychobiology 1997;35:16-23. PubMed
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Resveratrol 24 references
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