Liposomal Glutathione Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Liposomal Glutathione against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Liposomal Glutathione is a dietary supplement by Core Med Science with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, skin lightening or brightening, detoxification support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Liposomal Glutathione by Core Med Science
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product has 3 active ingredients. Glycerin is a humectant (moisture-drawing compound) that's well known for easing constipation and is used here as a delivery vehicle.
L-glutathione is an antioxidant your body makes naturally; it's the main active ingredient you're taking this for. Phosphatidylcholine is a phospholipid — a type of fat molecule — that supports cell membranes and liver function.
The liposome blend wraps these ingredients in a lipid shell to help your body absorb them more easily. The product also contains purified water, natural flavors, stevia, and potassium sorbate as inactive ingredients.
Does it work?
Not established
The evidence for L-glutathione is mixed. It's possibly effective for reducing nerve damage from the chemotherapy drug cisplatin, but the data on Alzheimer's disease, fatty liver disease, cataracts, and athletic performance is insufficient — we don't yet have reliable evidence it works for those.
Glycerin is likely effective for constipation and possibly effective for dry skin conditions, but possibly ineffective for stroke and meningitis. Phosphatidylcholine is possibly effective for ulcerative colitis but has insufficient evidence for liver disease, Alzheimer's disease, and anxiety.
How safe is it?
Well-documented data
Glycerin is generally well tolerated in normal amounts but can cause bloating, nausea, diarrhea, dizziness, and headache when taken orally in larger doses. L-glutathione appears well tolerated short-term by mouth, though long-term safety isn't established; inhaled forms can trigger airway narrowing and shortness of breath in people with asthma.
During pregnancy, there isn't enough reliable safety data for L-glutathione — the facts advise against it unless your doctor advises otherwise. During breastfeeding, L-glutathione safety is also unclear, so caution and avoidance are advised.
Phosphatidylcholine is generally well tolerated but may cause bloating, diarrhea, nausea, and vomiting at higher doses. For pregnancy, choline (a component of phosphatidylcholine) is needed, but supplement safety beyond food sources isn't well studied — check with your doctor.
Breastfeeding safety data is also limited; speak with your healthcare provider first.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check in this product. That said, always confirm your exact medications with your own pharmacist or doctor before you start, especially if you take multiple drugs.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.
This is a liquid supplement built around L-glutathione, an antioxidant with some evidence for cisplatin-related nerve damage but unproven benefits for other common uses. It's generally well tolerated in the short term, though larger doses of glycerin or phosphatidylcholine can cause digestive upset.
If you're pregnant or breastfeeding, the safety data for L-glutathione and phosphatidylcholine is thin — talk it over with your doctor or pharmacist before starting. No medication interactions are documented for these ingredients, but that's not a substitute for checking your own prescriptions with your pharmacist.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Liposomal Glutathione, straight from the product label.
| Brand | Core Med Science |
|---|---|
| Barcode (UPC) | X000SD7Q4N |
| Net contents | 4 fl. Oz.; 120 mL |
| Market status | On market |
| Date entered into DSLD | Jul 23, 2020 |
| DSLD ID | 229275 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Liposomal Glutathione by Core Med Science, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Glycerin | 0 NP | -- |
| L-Glutathione | 500 mg | -- |
| Phosphatidylcholine Complex | 0 NP | -- |
| Liposome Proprietary Blend | 500 mg | -- |
Other ingredients: purified Water, Natural Flavors, Stevia, Potassium Sorbate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Physician formulated
Non-GMO Liposomes
Vegan
Non-Soy Ingredients
Supports liver, brain and immune function Phase 2 biotransformation and detoxification Critical for energy, focus and concentration
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Take 4 milliliters (just over one teaspoon) daily, or as directed by your healthcare provider. Mix with water or juice if desired. Shake before using.
Use within 45 days of opening.
Storage
Refrigerate after opening.
Precautions
As with all dietary supplements, seek the advice of your qualified healthcare provider prior to use of this product.
Pregnant or lactating women should consult their qualified healthcare provider prior to use.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Setria is a registered trademark of KYOWA HAKKO BIO CO., LTD. The Power to Protect is a Trademark of KYOWA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Liposomal Glutathione by Core Med Science label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Liposomal Glutathione by Core Med Science
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size4 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Glutathione
No knowninteractions
Glutathione is a powerful antioxidant your body makes naturally, and many people take it as a supplement hoping for skin, detox, or anti-aging benefit...
L-Glutathione monograph & interactionsLiposome Proprietary Blend
Other (inactive) ingredients: Purified Water, Natural Flavors, Stevia, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.
Liposomal Glutathione by Core Med Science Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Liposomal Glutathione. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Liposomal Glutathione, from the product label.
Core Med Science
See all Core Med Science products- Name
- IV for Life
- Street Address
- 2973 Harbor Blvd. #322
- City
- Costa Mesa
- State
- CA
- ZipCode
- 92626
Liposomal Glutathione by Core Med Science: Common Questions
Does Liposomal Glutathione by Core Med Science interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does L-glutathione do?
Is this safe to take if I have asthma?
Can I take this while pregnant?
Can I take this while breastfeeding?
What side effects might I have?
Why is this a liquid instead of a pill?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Liposomal Glutathione is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Liposomal Glutathione’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Glutathione
Glutathione is a powerful antioxidant your body makes naturally, and many people take it as a supplement hoping for skin, detox, or anti-aging benefits. However, strong human evidence is lim...
Read the full Glutathione monograph → Herb & supplement monographGlycerol
Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well established as a laxative and a skin and eye moi...
Read the full Glycerol monograph → Herb & supplement monographPhosphatidylcholine
Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, but solid human evidence is limited for mo...
Read the full Phosphatidylcholine monograph →Sources & How We Checked
Liposomal Glutathione's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 24 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Glycerol 8 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Wagner DR. Hyperhydrating with glycerol: implications for athletic performance. J Am Diet Assoc 1999;99:207-12. PubMed
- Yu YL, Kumana CR, Lauder IJ, et al. Treatment of acute cortical infarct with intravenous glycerol. A double-blind, placebo-controlled randomized trial. Stroke 1993;24:1119-24. PubMed
- Frei A, Cottier C, Wunderlich P, Ludin E. Glycerol and dextran combined in the therapy of acute stroke. A placebo-controlled, double-blind trial with a planned interim analysis. Stroke 1987;18:373-9. PubMed
- Balaskas E, Szepietowski JC, Bessis D, Ioannides D, Ponticelli C, Ghienne C, Taberly A, Dupuy P. Randomized, double-blind study with glycerol and paraffin in uremic xerosis. Clin J Am Soc Nephrol. 2011 Apr;6(4):748-52. PubMed
- Blanchet-Bardon C, Tadini G, Machado Matos M, Delarue A. Association of glycerol and paraffin in the treatment of ichthyosis in children: an international, multicentric, randomized, controlled, double-blind study. J Eur Acad Dermatol Venereol. 2012 Aug;26 PubMed
- Kajita N, Kanamori K, Yamamoto S, Yoshida K. Generalized Urticaria Caused by a Glycerin Enema in an Infant. J Investig Allergol Clin Immunol 2022;32(4):318-319. PubMed
- Suzuki R, Fukuyama K, Miyazaki Y, Namiki T. Contact urticaria syndrome and protein contact dermatitis caused by glycerin enema. JAAD Case Reports. 2016;2:108-10. PubMed
Glutathione 1 reference
- Marrades RM, Roca J, Barbera JA, et al. Nebulized glutathione induces bronchoconstriction in patients with mild asthma. Am J Respir Crit Care Med 1997;156(2 Pt 1):425-30. PubMed
Phosphatidylcholine 15 references
- Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
- Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
- Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
- Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
- Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
- Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
- Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
- Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
- Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
- Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
- Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
- Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
- Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
- Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC