No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Liposomal Glutathione Original Flavor Ingredients & Drug Interactions

by Core Med Science

Liquid Category: Other Combinations
No known interaction
The interaction bottom line No known interaction

Liposomal Glutathione Original Flavor is a dietary supplement by Core Med Science with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, skin lightening or brightening, detoxification support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Liposomal Glutathione Original Flavor by Core Med Science

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 3 active ingredients.
  • “Liposome Proprietary Blend” is a proprietary blend — the label gives one combined amount (500 mg) without saying how much of each component you get.

This product has three active ingredients. Glycerin is a humectant and osmotic agent — it draws water into the intestines and is used for constipation relief.

L-glutathione is an antioxidant your body makes naturally; it's included here for potential support in certain conditions. Phosphatidylcholine complex is a phospholipid that supports cell membranes and may help with digestion and liver function.

The inactive ingredients are purified water, natural flavors, stevia leaf extract, and potassium sorbate (a preservative).

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: liver, brain and immune function; detoxification.
  • We looked for evidence on: Alcohol-related liver disease, Alzheimer disease, Anxiety, Cirrhosis, Cognitive function, Dementia — and 4 related terms.
  • The closest evidence on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alcohol-related liver disease (Natural Medicines).
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Anxiety, Hepatic encephalopathy, Hepatitis C, and more.

The evidence varies by ingredient and use. Glycerin is likely effective for constipation but likely ineffective for stroke and prematurity; it's possibly effective for athletic performance and possibly ineffective for meningitis.

L-glutathione is possibly effective for cisplatin-induced nerve damage (a chemotherapy side effect), but the evidence for Alzheimer disease, fatty liver disease, athletic performance, and cataracts is insufficient — meaning we don't have solid proof it works for those yet. Phosphatidylcholine is possibly effective for ulcerative colitis, but evidence for fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety is insufficient.

The evidence, ingredient by ingredient Glutathione Glycerol Phosphatidylcholine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

All three active ingredients are generally well tolerated in normal amounts. Glycerin can cause bloating, diarrhea, nausea, vomiting, dizziness, and headache when taken by mouth, especially at larger doses — large amounts may also cause stomach upset and dehydration.

L-glutathione is generally well tolerated short-term orally, but long-term safety isn't fully established; the inhaled form can cause airway narrowing and shortness of breath in people with asthma. Phosphatidylcholine is generally well tolerated at food and supplement levels, but high doses may cause digestive upset, bloating, diarrhea, altered taste, nausea, vomiting, sweating, and itching.

For pregnancy: L-glutathione safety data is insufficient — the facts advise against it unless your doctor says otherwise. Phosphatidylcholine and glycerin have limited pregnancy data; ask your doctor before using medicinal amounts.

For breastfeeding: L-glutathione safety data is insufficient and caution is advised; phosphatidylcholine has limited data — speak with your healthcare provider first. Data on glycerin during breastfeeding isn't on file.

Side effects, ingredient by ingredient Glutathione Glycerol Phosphatidylcholine

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. Still, run your exact medications through the search tool on this page to be sure — it's a quick step that can catch something we might have missed.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product may be worth considering if you're interested in antioxidant support or potential help with cisplatin side effects or ulcerative colitis, though the evidence for other uses is still being studied. Be aware that glycerin and phosphatidylcholine can cause digestive symptoms in some people, especially at higher doses.

If you're pregnant, breastfeeding, have asthma, or take any regular medications, talk to your pharmacist or doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Liposomal Glutathione Original Flavor, straight from the product label.

Brand Core Med Science
Barcode (UPC) X0027HXXZT
Net contents 4 fl. Oz.; 120 mL
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 229274
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Liposomal Glutathione Original Flavor by Core Med Science, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 mL
Maximum serving Sizes:
4 mL
Servings per container
30
UPC/BARCODE
X0027HXXZT
IngredientAmount% DV
Glycerin0 NP--
L-Glutathione500 mg--
Phosphatidylcholine Complex0 NP--
Liposome Proprietary Blend500 mg--

Other ingredients: purified Water, Natural Flavors, Stevia leaf extract, Potassium Sorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Non-GMO Liposomes

Vegan

Non-Soy Ingredients

Supports liver, brain and immune function Phase 2 biotransformation and detoxification Critical for energy, focus and concentration

Manufactured in the USA in a cGMP facility

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 4 mL (3/4 teaspoon) on an empty stomach then wait 30-45 minutes before eating or taking other supplements. Shake before using.

Use within 45 days of opening.

Storage

Refrigerate after opening.

Precautions

As with all dietary supplements, seek the advice of your qualified healthcare provider prior to use of this product.

Pregnant or lactating women should consult their qualified healthcare provider prior to use.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Setria is a registered trademark of KYOWA HAKKO BIO CO., LTD. The Power to Protect is a Trademark of KYOWA

See for yourself

Liposomal Glutathione Original Flavor by Core Med Science label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Liposomal Glutathione Original Flavor by Core Med Science

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Glutathione

No known
interactions
500 mg per serving

Glutathione is a powerful antioxidant your body makes naturally, and many people take it as a supplement hoping for skin, detox, or anti-aging benefit...

L-Glutathione monograph & interactions

Liposome Proprietary Blend

500 mg per serving

Other (inactive) ingredients: Purified Water, Natural Flavors, Stevia leaf extract, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Liposomal Glutathione Original Flavor by Core Med Science Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Liposomal Glutathione Original Flavor. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Liposomal Glutathione Original Flavor, from the product label.

Core Med Science

See all Core Med Science products
Name
IV for Life
Street Address
2973 Harbor Blvd. #322
City
Costa Mesa
State
CA
ZipCode
92626
Pharmacist Counseling Corner

Liposomal Glutathione Original Flavor by Core Med Science: Common Questions

Does Liposomal Glutathione Original Flavor by Core Med Science interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Liposomal Glutathione Original Flavor. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Liposomal Glutathione Original Flavor contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with fatty liver disease?
Both L-glutathione and phosphatidylcholine have been studied for nonalcoholic fatty liver disease, but the evidence isn't solid yet — we rate it as insufficient. Talk to your doctor about whether this product makes sense for you.
Can I take this while pregnant?
L-glutathione safety data in pregnancy is insufficient, and the facts advise against it unless your doctor says otherwise. Phosphatidylcholine and glycerin also have limited pregnancy data. Check with your doctor or pharmacist for personalized advice.
Can I take this while breastfeeding?
L-glutathione safety while breastfeeding is insufficient and caution is advised. Phosphatidylcholine has limited data — talk with your healthcare provider first. Safety data on glycerin during breastfeeding isn't on file, so ask your doctor.
What side effects should I watch for?
Glycerin and phosphatidylcholine can both cause bloating, diarrhea, nausea, and vomiting. Glycerin may also cause dizziness and headache; phosphatidylcholine may cause altered taste and sweating. If you have asthma, know that the inhaled form of glutathione can cause airway narrowing and shortness of breath.
Is this product good for athletic performance?
Glycerin is possibly effective for athletic performance, though the evidence isn't ironclad. L-glutathione's evidence for athletic performance is insufficient — we don't have solid proof it works yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Liposomal Glutathione Original Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Liposomal Glutathione Original Flavor label
Sources

Sources & How We Checked

Liposomal Glutathione Original Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycerol 8 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Wagner DR. Hyperhydrating with glycerol: implications for athletic performance. J Am Diet Assoc 1999;99:207-12. PubMed
  3. Yu YL, Kumana CR, Lauder IJ, et al. Treatment of acute cortical infarct with intravenous glycerol. A double-blind, placebo-controlled randomized trial. Stroke 1993;24:1119-24. PubMed
  4. Frei A, Cottier C, Wunderlich P, Ludin E. Glycerol and dextran combined in the therapy of acute stroke. A placebo-controlled, double-blind trial with a planned interim analysis. Stroke 1987;18:373-9. PubMed
  5. Balaskas E, Szepietowski JC, Bessis D, Ioannides D, Ponticelli C, Ghienne C, Taberly A, Dupuy P. Randomized, double-blind study with glycerol and paraffin in uremic xerosis. Clin J Am Soc Nephrol. 2011 Apr;6(4):748-52. PubMed
  6. Blanchet-Bardon C, Tadini G, Machado Matos M, Delarue A. Association of glycerol and paraffin in the treatment of ichthyosis in children: an international, multicentric, randomized, controlled, double-blind study. J Eur Acad Dermatol Venereol. 2012 Aug;26 PubMed
  7. Kajita N, Kanamori K, Yamamoto S, Yoshida K. Generalized Urticaria Caused by a Glycerin Enema in an Infant. J Investig Allergol Clin Immunol 2022;32(4):318-319. PubMed
  8. Suzuki R, Fukuyama K, Miyazaki Y, Namiki T. Contact urticaria syndrome and protein contact dermatitis caused by glycerin enema. JAAD Case Reports. 2016;2:108-10. PubMed

See these in context on the Glycerol monograph →

Glutathione 1 reference
  1. Marrades RM, Roca J, Barbera JA, et al. Nebulized glutathione induces bronchoconstriction in patients with mild asthma. Am J Respir Crit Care Med 1997;156(2 Pt 1):425-30. PubMed

See these in context on the Glutathione monograph →

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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