Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

PC Complex Ingredients & Drug Interactions

by Core Med Science

Liquid Category: Fat/fatty Acid
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

PC Complex is a dietary supplement by Core Med Science with 5 active ingredients. Its ingredients are commonly taken for cooking and frying, skin moisturizing, hair and scalp care.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sunflower Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of PC Complex by Core Med Science

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Phospholipid Complex” is a proprietary blend — the label gives one combined amount (5,200 mg) without saying how much of each component you get.

PC Complex is a liquid supplement with 5 active ingredients. The main ones are sunflower oil and phosphatidylcholine — the latter is a natural compound found in all your cells that plays a role in cell structure and brain function.

The product also contains a phospholipid complex (a blend of similar fat-soluble compounds) and two other phospholipids called phosphatidylethanolamine and phosphatidylinositol. There are no inactive fillers or other ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: phospholipids for cells and brain support.
  • We looked for evidence on: Alzheimer disease, Dementia, Memory, Nonalcoholic fatty liver disease (NAFLD), Ulcerative colitis, Cognitive decline — and 2 related terms.
  • The strongest evidence on file: Phosphatidylcholine is rated "Possibly Effective" for Ulcerative colitis (Natural Medicines).
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Memory, Dementia, Nonalcoholic fatty liver disease (NAFLD).

Sunflower oil is possibly effective for lowering cholesterol and supporting heart health. Phosphatidylcholine is possibly effective for ulcerative colitis; for other conditions in this product — fatty liver disease, alcohol-related liver damage, Alzheimer's disease, and anxiety — the evidence we hold is insufficient to rate it.

The effectiveness of phosphatidylethanolamine, phosphatidylinositol, and minor glycolipids is not established in our data.

The evidence, ingredient by ingredient Sunflower Oil Phosphatidylcholine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sunflower oil is generally well tolerated in normal dietary amounts; if you're using it as a concentrated supplement, talk with your doctor first. A small number of people sensitive to plants in the ragweed family (like daisies and chrysanthemums) may have an allergic reaction, though sunflower oil's protein content is very low.

Phosphatidylcholine is generally well tolerated, but high doses may cause digestive upset, bloating, diarrhea, nausea, or altered taste. When taken orally it can also increase sweating or itching in some people.

For pregnancy, sunflower oil is rated likely safe. Phosphatidylcholine data on supplement use in pregnancy beyond food sources is not well studied — talk with your doctor before taking it while pregnant.

We don't have reliable data on either ingredient's use while breastfeeding; check with your healthcare provider first.

Side effects, ingredient by ingredient Sunflower Oil Phosphatidylcholine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Sunflower Oil.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using this product if you take antidiabetes drugs (blood sugar medications) — sunflower oil may decrease their effectiveness and raise fasting blood glucose levels, possibly requiring a dose adjustment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

PC Complex may help with cholesterol and heart health through its sunflower oil, though evidence for some of its other uses is still uncertain. The key concern is people taking blood sugar medications — this product may weaken their effect.

If that applies to you, or you take any regular medication, talk it over with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about PC Complex, straight from the product label.

Brand Core Med Science
Barcode (UPC) X000X9GLEN
Net contents 8 Fluid Ounce(s); 240 mL
Market status On market
Date entered into DSLD Jan 22, 2022
DSLD ID 258484
Product type Fat/fatty Acid
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for PC Complex by Core Med Science, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
8 Milliliter(s)
Maximum serving Sizes:
8 Milliliter(s)
Servings per container
30
UPC/BARCODE
X000X9GLEN
IngredientAmount% DV
Sunflower Oil0 NP--
Phosphatidylcholine0 NP--
Phospholipid Complex5200 mg--
Phosphatidylethanolamine0 NP--
Phosphatidylinositol0 NP--
minor Glycolipids0 NP--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Phospholipid complex

Formulation

Physician formulated

Non-GMO liposomes Non-Soy ingredients

PC Complex uses certified non-GMO sunflower lecithin to deliver phospholipids to your cells and brain for maximum support

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 2 teaspoons daily with food or alone.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

As with all dietary supplements, seek the advice of your qualified healthcare provider prior to use of this product.

Pregnant or lactating women should contact their qualified healthcare provider prior to use.

See for yourself

PC Complex by Core Med Science label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in PC Complex by Core Med Science

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size8 Milliliter(s) Dosage formLiquid Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Phospholipid Complex

5200 mg per serving

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

PC Complex by Core Med Science Drug Interactions

Want to check YOUR meds against PC Complex?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in PC Complex with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sunflower Oil1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, sunflower oil might decrease the effectiveness of antidiabetes medications.
A diet using sunflower oil as a fat source can cause increased fasting blood glucose levels in patients with type 2 diabetes. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for PC Complex, from the product label.

Core Med Science

See all Core Med Science products
Name
IV for Life
Street Address
2973 Harbor Blvd. #322
City
Costa Mesa
State
CA
ZipCode
92626
Pharmacist Counseling Corner

PC Complex by Core Med Science: Common Questions

Does PC Complex by Core Med Science interact with any medications?
Yes. Based on its ingredients, PC Complex has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
PC Complex contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have type 2 diabetes?
Not without checking with your doctor first. Sunflower oil in this product can raise fasting blood glucose levels and may weaken how well your diabetes medications work, so you and your doctor may need to adjust your treatment plan before you start.
What's phosphatidylcholine, and what does it do?
It's a natural fat-soluble compound present in all your cells that supports cell structure and brain function. This product uses it because there's evidence it may help with ulcerative colitis, though we don't have solid data yet for some other uses it's marketed for.
Are there any common side effects?
Phosphatidylcholine can cause bloating, diarrhea, nausea, altered taste, or increased sweating in some people, especially at higher doses. Start with the recommended dose and talk to your pharmacist if you notice any stomach upset.
Is this safe to use while I'm pregnant?
Sunflower oil is likely safe in pregnancy. We don't have enough reliable data on phosphatidylcholine supplements beyond food sources during pregnancy — talk with your doctor before using this product if you're expecting.
Can I take this while breastfeeding?
We don't have reliable data on supplement use of these ingredients while breastfeeding. Check with your healthcare provider to see if it's right for you.
Does this product have any fillers or other ingredients?
No — the label lists only the active ingredients and no other inactive fillers or additives.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if PC Complex is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

PC Complex label
Sources

Sources & How We Checked

PC Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sunflower Oil 2 references
  1. Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed
  2. An J. Anaphylaxis to sunflower seed with tolerance to sunflower oil: A case report. Medicina (Kaunas) 2021;57(7):661. PubMed

See these in context on the Sunflower Oil monograph →

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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