Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

LipoValin Ingredients & Drug Interactions

by SeroVital

LipoValin label
See full label image
Tablet Or Pill Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking LipoValin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

LipoValin is a dietary supplement by SeroVital with 6 active ingredients. Its ingredients are commonly taken for common cold and immune support, antioxidant support, skin health and collagen formation.Based on those ingredients, 2,226 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Japanese Glucomannan, Purified, Cumin Seed Extract, Vitamin C. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against LipoValin by SeroVital

Ask about any prescription or over-the-counter medication and we check it for interactions with LipoValin by SeroVital — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of LipoValin by SeroVital

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 6 active ingredients.
  • “WLV5 Proprietary Blend” is a proprietary blend — the label gives one combined amount (650 mg) without saying how much of each component you get.

LipoValin contains six active ingredients: vitamin C, olive leaf extract, a proprietary blend called WLV5, lady's mantle leaf extract, cumin seed extract, wild mint leaf extract, and Japanese glucomannan. The inactive ingredients are microcrystalline cellulose, dicalcium phosphate, magnesium stearate, silicon dioxide, hypromellose, hydroxypropylcellulose, tricalcium phosphate, titanium dioxide, polyethylene glycol, talc, polydextrose, vegetable juice, maltodextrin, monoglycerides, and diglycerides.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: weight loss and appetite control.
  • We looked for evidence on: Obesity, overweight, body weight management, metabolic health.
  • The closest evidence on file: Glucomannan is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).
  • Also on file: Cumin is rated "Insufficient Reliable Evidence To Rate" for Obesity.

Vitamin C is effective for vitamin C deficiency and possibly effective for anemia, atrial fibrillation, cataracts, and exercise-induced respiratory infections. Glucomannan is possibly effective for constipation, diabetes, and high cholesterol.

For olive leaf extract, cumin seed extract, lady's mantle leaf extract, and wild mint leaf extract, the evidence we hold does not establish effectiveness for their typical uses; the data rates them as having insufficient evidence or no rating at all.

The evidence, ingredient by ingredient Vitamin C Olive Alchemilla Cumin Wild Mint Glucomannan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin C is generally well tolerated at normal dietary and supplement doses, though very high doses can cause abdominal cramps, heartburn, diarrhea, nausea, and kidney stones—especially above 2 grams daily. During pregnancy, normal amounts from food and prenatal vitamins are fine, but high-dose supplements should be avoided unless your doctor advises otherwise.

Olive leaf extract seems well tolerated in studies and is safe as a food, though concentrated supplements are less studied. Cumin used as a spice is generally safe, but supplement doses have limited safety data; a rare case of anaphylaxis has been reported.

Lady's mantle leaf extract is considered low-risk in small amounts, but human safety data are limited; safety information during pregnancy and breastfeeding is insufficient, so both should be avoided unless approved by your doctor. Wild mint leaf extract is generally well tolerated as a tea, but medicinal doses and concentrated essential oil are not well studied.

Glucomannan is generally well tolerated with plenty of water but can cause bloating, gas, constipation, diarrhea, and nausea—especially at doses above 3 grams daily. Serious but rare side effects include choking and intestinal blockage if taken without enough fluid.

Side effects, ingredient by ingredient Vitamin C Olive Alchemilla Cumin Wild Mint Glucomannan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 6 matched ingredients can interact with medications — Glucomannan, Cumin, Alchemilla, Vitamin C.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments; diabetes medications.
  • For scale: 2,227 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking LipoValin, double-check with your doctor or pharmacist if you use blood thinners like warfarin or antiplatelet drugs such as aspirin or clopidogrel (cumin and vitamin C), diabetes medications (cumin and glucomannan), chemotherapy drugs that work via free radicals such as doxorubicin (vitamin C), the antipsychotic fluphenazine, the antibiotic rifampin (cumin), the HIV drug indinavir, levothyroxine for thyroid disease, or any other oral medications—glucomannan can reduce how much of them your body absorbs. Use the medication checker on this page to search your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

LipoValin may be considered by people looking for support with constipation, cholesterol, or blood sugar, based on glucomannan and vitamin C evidence. You should be especially careful if you take blood thinners, diabetes medications, certain psychiatric or antibiotic drugs, or chemotherapy—vitamin C and cumin interact with several of these classes.

Because this product affects over 2,200 individual medications, check your exact prescriptions with the tool on this page, and talk with your doctor or pharmacist before adding LipoValin to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about LipoValin, straight from the product label.

Brand SeroVital
Barcode (UPC) 681168860141
Net contents 30 Tablet(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 308360
Product type Botanical With Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for LipoValin by SeroVital, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
30
UPC/BARCODE
681168860141
IngredientAmount% DV
Vitamin C22 mg24%
Olive Leaf Extract0 NP--
WLV5 Proprietary Blend650 mg--
Lady's Mantle Leaf Extract0 NP--
Cumin Seed Extract0 NP--
Wild Mint Leaf Extract0 NP--
Japanese Glucomannan, Purified0 NP--

Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Magnesium Stearate, Silicon Dioxide, Hypromellose, Hydroxypropylcellulose, Tricalcium Phosphate, Titanium Dioxide, Polyethylene Glycol, Talc, Polydextrose, Vegetable juice, Maltodextrin, Monoglycerides, Diglycerides, Medium Chain Triglycerides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Two double-blind, placebo-controlled clinical trials were conducted on LipoValin. Participants were asked not to change their diet or exercise routine. In a combined analysis of these studies, participants lost on average: 8.6 pounds 2.9 inches around the waist 4.8% body weight 1 pound per week In a combined analysis on two randomized, double-blind, placebo-controlled clinical trials, the placebo group experienced statistically insignificant results. They lost an average of .88 pounds, .6% body weight, and .63 inches around the waist.

Clinically tested to promote weight loss Results from a combined analysis of 2 clinical trials: Reduced body weight and BMI Decreased average waist circumference by 2.9 inches Suppressed appetite Decreased cravings for sweets Lose up to 8.6 lbs

Brand IP Statement(s)

The Smart Release compound in LipoValin is protected by U.S. Patent Number 9,114,091.

Copyright 2022 All Rights Reserved.

General Statements

This box was designed in an oversized manner to discourage pilferage.

We solve problems with science. That means clinical studies, research that's been presented around the world, and products that have created an entirely new well-beauty category in the anti-aging industry. But most importantly, it means skin- and body-rejuvenating solutions capable of transforming you. Cutting-edge research Clinically validated ingredients Category-defining formulas Discovery Innovation Science Research

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take 1 tablet before breakfast or lunch. Use in conjunction with any sensible diet and exercise program. Individual results will vary.

Precautions

Warning: Do not exceed suggested daily serving.

Not for use by individuals under the age of 18 years.

Do not use if pregnant or nursing. Consult your physician prior to use if you are taking medication or have a medical condition.

Do not use if inner safety seal is broken or missing. Use only as directed.

Keep out of reach of children.

Product resale allowed only through authorized representatives. International distribution is not authorized without prior written approval.

Storage

Store at controlled room temperature: 15 degrees - 30 degrees C/59 degrees - 86 degrees F.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

LipoValin by SeroVital label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

LipoValin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in LipoValin by SeroVital

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin C

Interacts with
207 drugs
22 mg per serving Form: Ascorbic Acid

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...

Vitamin C monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Magnesium Stearate, Silicon Dioxide, Hypromellose, Hydroxypropylcellulose, Tricalcium Phosphate, Titanium Dioxide, Polyethylene Glycol, Talc, Polydextrose, Vegetable juice, Maltodextrin, Monoglycerides, Diglycerides, Medium Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.

Interaction report

LipoValin by SeroVital Drug Interactions

Want to check YOUR meds against LipoValin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,226Drugs
2,091 Moderate 135 Minor

Ingredients driving the most interactions

Japanese Glucomannan, Purified 2,022
Cumin Seed Extract 211
Vitamin C 207
Lady's Mantle Leaf Extract 198

Individual Drug Interactions

The ingredients in LipoValin interact with 2,226 drugs. Click any drug to see the details.

4 of the 6 ingredients in LipoValin interact with drugs. Each result below shows which ingredient is responsible. Japanese Glucomannan, Purified Cumin Seed Extract Vitamin C Lady's Mantle Leaf Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in LipoValin with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Japanese Glucomannan, Purified1 drug type · 2,022 drugs

Oral Drugs

Theoretically, glucomannan may decrease absorption of drugs taken orally.
Due to its viscosity and bulking effects, there is concern that glucomannan can decrease the absorption of oral drugs. A small clinical study in healthy volunteers shows that taking glyburide 2.5 mg plus glucomannan 3.9 grams with breakfast reduces plasma levels of glyburide when compared with breakfast and glyburide alone. In addition, animal research demonstrates this effect on amoxicillin, but shows increased absorption of metronidazole. This mouse model also demonstrates that metronidazole elimination is prolonged, but amoxicillin elimination is enhanced by 38%; glucomannan may also affect the distribution of some drugs. To avoid changes in absorption, take glucomannan 30-60 minutes after taking oral drugs.

Likelihood Probable Evidence B
Japanese Glucomannan, Purified full monograph & interactions

Cumin Seed Extract3 drug types · 211 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, cumin might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
In vitro evidence suggests that cumin can inhibit platelet aggregation. Theoretically, cumin might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, cumin might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that cumin can lower blood sugar in diabetic animals. However, research in humans with and without diabetes has found conflicting results.

Likelihood Probable Evidence D
Rifampin (Rifadin)

Theoretically, cumin might increase the effects and adverse effects of rifampin.
Animal research suggests that an aqueous extract of cumin containing a specific flavonoid glycoside can increase the bioavailability and plasma levels of rifampin.

Likelihood Possible Evidence D
Cumin Seed Extract full monograph & interactions

Vitamin C13 drug types · 207 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Aluminum

Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.

Likelihood Probable Evidence B
Antitumor Antibiotics

Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Estrogens

Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.

Likelihood Probable Evidence B
Fluphenazine (Prolixin)

Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.

Likelihood Possible Evidence D
Indinavir (Crixivan)

Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.

Likelihood Probable Evidence B
Warfarin (Coumadin)

High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.

Likelihood Probable Evidence B
Aspirin

Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.

Likelihood Possible Evidence B
Choline Magnesium Trisalicylate (Trilisate)

Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Niacin

Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Salsalate (Disalcid)

Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Vitamin C full monograph & interactions

Lady's Mantle Leaf Extract1 drug type · 198 drugs

Topical Drugs

While no side effects have been reported from orally using Alchemilla, a clinical study titled "Treatment of Aphthous Stomatitis with Topical Alchemilla vulgaris in Glycerine," published in Clinical Drug Investigation (https://pubmed.ncbi.nlm.nih.gov/17163290/), found that local mouth irritation occurred after applying a commercial product containing 3% alchemilla extract and glycerol (Aphtarine, Laboratoires Biosphere). Aphtarine was non-irritating in 68.2% of cases within 2-3 days, in 18.8% of cases within 4-7 days, and in 13.6% of cases with moderate irritation. Theoretically, combining Alchemilla with other potentially irritating topical products could increase the risk of local irritation and discomfort. The drug in this drug interaction monograph is available in a topical dosage form. There is no interaction expected from the oral dosage form of the drug.

Likelihood Possible Evidence D
Lady's Mantle Leaf Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for LipoValin, from the product label.

SeroVital

See all SeroVital products
Name
SeroVital, LLC
City
Salt Lake City
State
UT
ZipCode
84116
Phone Number
1-800-898-5153
Web Address
SeroVital.com
Pharmacist Counseling Corner

LipoValin by SeroVital: Common Questions

Does LipoValin by SeroVital interact with any medications?
Yes. Based on its ingredients, LipoValin has a known interaction with 2,226 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
LipoValin contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take LipoValin if I'm pregnant?
The vitamin C in this product is likely safe during pregnancy at normal doses, but avoid high-dose supplements unless your doctor says otherwise. For lady's mantle leaf extract, safety information during pregnancy is insufficient—avoid it unless your doctor approves. Safety data for olive leaf extract, cumin, wild mint, and glucomannan during pregnancy is not clearly established in our records, so discuss this product with your doctor or pharmacist for personalized advice.
Is it safe while breastfeeding?
Vitamin C at normal doses is likely safe while breastfeeding. Lady's mantle leaf extract has insufficient safety information while breastfeeding and should be avoided unless your healthcare provider approves. Safety data for the other ingredients while breastfeeding is not well established, so check with your doctor or pharmacist before taking it.
What is glucomannan and what does it do?
Glucomannan is a soluble fiber extract that is possibly effective for constipation, blood sugar control, and high cholesterol. It works by absorbing water and adding bulk to stools. It can also slow how quickly your body absorbs oral medications, so take it several hours before or after prescription drugs.
Can LipoValin cause side effects?
Vitamin C can cause stomach cramps, heartburn, and diarrhea—more likely at high doses. Glucomannan often causes bloating, gas, and constipation or diarrhea, especially above 3 grams daily; take it with plenty of water to avoid choking or blockage. Cumin may cause upset stomach or allergic reactions in sensitive people. Olive leaf extract and wild mint are generally well tolerated.
Does this product actually work?
Vitamin C is proven effective for vitamin C deficiency and possibly effective for anemia, atrial fibrillation, cataracts, and exercise infections. Glucomannan is possibly effective for constipation, diabetes, and high cholesterol. For the other ingredients—olive leaf, cumin, lady's mantle, and wild mint—the evidence in our data is either not established or rated as insufficient to say they work for their typical uses.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

LipoValin label
Go deeper

The Full Monographs Behind LipoValin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin C

Interacts with 207 drugs

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...

Read the full Vitamin C monograph → Herb & supplement monograph

Olive

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyrosol. Olive oil as part of a Mediterrane...

Read the full Olive monograph → Herb & supplement monograph

Alchemilla

Interacts with 198 drugs

Alchemilla (lady's mantle) is a European herb traditionally used for digestive complaints, women's health issues, and as an astringent for skin and wounds. Solid human research is very limit...

Read the full Alchemilla monograph → Herb & supplement monograph

Cumin

Interacts with 211 drugs

Cumin is a common cooking spice that has a long history in traditional medicine for digestion and other complaints. Food amounts are generally safe for most people, but the evidence for medi...

Read the full Cumin monograph → Herb & supplement monograph

Wild Mint

Wild mint is an aromatic herb in the mint family used traditionally for digestive complaints, nausea, and congestion. Solid human studies on wild mint specifically are limited, so most evide...

Read the full Wild Mint monograph → Herb & supplement monograph

Glucomannan

Interacts with 2,022 drugs

Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and modestly lowering cholesterol. It is gener...

Read the full Glucomannan monograph →
Sources

Sources & How We Checked

LipoValin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 81 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin C 51 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
  3. Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
  4. Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
  5. Dwyer JH, Merz NB, Shirocre AM, et al. Progression of early atherosclerosis and intake of vitamin C and vitamin E from supplements and food. The Los Angeles Atherosclerosis Study. 41st Annual Conference on Cardiovascular Disease Epidemiology and Prevent
  6. Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-23. PubMed
  7. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  8. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
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See these in context on the Vitamin C monograph →

Olive 2 references
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See these in context on the Olive monograph →

Alchemilla 1 reference
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See these in context on the Alchemilla monograph →

Cumin 10 references
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See these in context on the Cumin monograph →

Wild Mint 2 references
  1. Peppermint Oil — NIH NCCIH Source
  2. Herbs at a Glance — NIH NCCIH Source

See these in context on the Wild Mint monograph →

Glucomannan 15 references
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  13. Health Canada Safety Alert. Health Canada Advises Canadians that natural health products containing glucomannan may cause serious choking if used with insufficient fluid. January 29, 2010. Alert # RA-110003825. https://healthycanadians.gc.ca/recall-alert-
  14. Mortensen A, Aguilar F, Crebelli, et al. EFSA Panel on Food Additives and Nutrient Sources added to Food. Re-evaluation of konjac gum (E 425 i) and konjac glucomannan (E425 ii) as food additives. EFSA Journal 2017;15(6):4864.
  15. Zhang Y, Aldamarany WAS, Song G, et al. Influence of konjac glucomannan and its derivatives on the oral pharmacokinetics of antimicrobial agent in antibiotics cocktails: Keep vigilant on dietary fiber supplement. Int J Biol Macromol 2023;251:126306. PubMed

See these in context on the Glucomannan monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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