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Dietary supplement

LJ100 25 mg Ingredients & Drug Interactions

by Advance Physician Formulas

LJ100 25 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking LJ100 25 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

LJ100 25 mg is a dietary supplement by Advance Physician Formulas with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are LJ100 Eurycoma longifolia root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against LJ100 25 mg by Advance Physician Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with LJ100 25 mg by Advance Physician Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of LJ100 25 mg by Advance Physician Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

LJ100 contains one active ingredient: Eurycoma longifolia root extract at 25 mg per capsule. It's enclosed in a vegetable capsule.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support male and female vitality.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence supports LJ100 possibly being effective for sexual desire. For athletic performance, the data suggests it's possibly ineffective.

The facts we hold don't establish reliable evidence for back pain, osteoporosis, or diabetes — the research is too thin or conflicting to say one way or the other.

The evidence, ingredient by ingredient Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Eurycoma longifolia is generally well tolerated in short-term studies, but we don't have solid long-term safety data or reliable information about product quality across brands. The safety data advises against it during pregnancy and while breastfeeding because of possible hormonal effects and incomplete safety information.

One concern: if the extract raises your testosterone beyond the normal range, you could develop testosterone-related side effects including acne, insulin resistance, and liver toxicity.

Side effects, ingredient by ingredient Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before you start if you take propranolol (Inderal) — this extract can weaken its effect. Also flag any medications your liver breaks down using the CYP1A2, CYP2C19, or CYP2A6 pathways, and any testosterone replacement therapy.

Your pharmacist can help you identify these.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

LJ100 may help with sexual desire, though it works best if you have low testosterone to begin with. If you take propranolol or any heart or blood-pressure medication, or if you're on testosterone replacement, you'll want to check with your doctor or pharmacist before starting.

Avoid it if you're pregnant or breastfeeding. Run your full medication list through the checker on this page.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about LJ100 25 mg, straight from the product label.

Brand Advance Physician Formulas
Barcode (UPC) 896996000359
Net contents 60 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 270313
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for LJ100 25 mg by Advance Physician Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
896996000359
IngredientAmount% DV
LJ100 Eurycoma longifolia root extract25 mg--

Other ingredients: Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Tongkat ali (Eurycoma longifolia) as LJ100 is a patented, standardized extract which may help support both male and female vitality.

Tongkat ali 100:1 extract LJ100 25 mg per serving

Precautions

Warnings: Keep out of reach of children.

Consult with a qualified healthcare professional prior to using this product. Sealed for your protection. Do not use if seal is missing or broken.

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy or gluten. Produced in a third-party registered cGMP compliant facility that may process other products containing these allergens or ingredients.

Storage

Store at room temperature, in a dry place. Protect product from excessive heat, freezing, humidity, and light.

Formulation

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy or gluten.

Doctor formulated

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, healthy adults take one capsule in the morning with or without food, or as recommended by a qualified healthcare professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

LJ100 25 mg by Advance Physician Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

LJ100 25 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in LJ100 25 mg by Advance Physician Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

LJ100 Eurycoma longifolia root extract

Interacts with
248 drugs
25 mg per serving Form: Eurypeptides, Glyco Saponins

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

LJ100 Eurycoma longifolia root extract monograph & interactions

Other (inactive) ingredients: Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

LJ100 25 mg by Advance Physician Formulas Drug Interactions

Want to check YOUR meds against LJ100 25 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
3 Moderate 245 Minor

Ingredients driving the most interactions

LJ100 Eurycoma longifolia root extract 248

Individual Drug Interactions

The ingredients in LJ100 25 mg interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in LJ100 25 mg interact with drugs. Each result below shows which ingredient is responsible. LJ100 Eurycoma longifolia root extract

Each ingredient & the kinds of drugs it affects

For each ingredient in LJ100 25 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

LJ100 Eurycoma longifolia root extract5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
LJ100 Eurycoma longifolia root extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for LJ100 25 mg, from the product label.

Advance Physician Formulas

See all Advance Physician Formulas products
Name
Advance Physician Formulas, Inc.
Street Address
17165 Von Karman Ave. Suite 109
City
Irvine
State
CA
ZipCode
92614
Web Address
physicianformulas.com
Pharmacist Counseling Corner

LJ100 25 mg by Advance Physician Formulas: Common Questions

Does LJ100 25 mg by Advance Physician Formulas interact with any medications?
Yes. Based on its ingredients, LJ100 25 mg has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
LJ100 25 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is LJ100 used for?
LJ100 is marketed for sexual desire. The evidence suggests it may help, though research is strongest in men with low testosterone. It's also been studied for athletic performance, but the data suggests it's not effective for that.
Can I take LJ100 if I'm pregnant or breastfeeding?
No. The safety data advises against it during pregnancy because of possible hormonal effects, and there isn't enough reliable safety information to recommend it while breastfeeding. Talk with your doctor or pharmacist about alternatives.
What are the side effects?
Short-term studies show it's generally well tolerated. The main concern is if it raises your testosterone too high — that can cause acne, insulin resistance, and liver problems. Long-term safety isn't well established.
Will LJ100 interact with my blood pressure medication?
If you take propranolol (Inderal), yes — the extract can reduce how well it works by about 29%. Check with your doctor or pharmacist before starting, especially if you're on any heart or blood-pressure drug.
Is there anything else I need to know before I start?
Long-term safety data is limited, and product quality can vary between brands. If you're on any prescription medication, use the interaction checker on this page with your full list before you buy.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if LJ100 25 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

LJ100 25 mg label
Go deeper

The Full Monographs Behind LJ100 25 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eurycoma Longifolia

Interacts with 248 drugs

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....

Read the full Eurycoma Longifolia monograph →
Sources

Sources & How We Checked

LJ100 25 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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