CoQ10 + PQQ Ingredients & Drug Interactions
What is this page for?
First and foremost: checking CoQ10 + PQQ against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CoQ10 + PQQ is a dietary supplement by Advance Physician Formulas with 2 active ingredients. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ubiquinol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CoQ10 + PQQ by Advance Physician Formulas
Ask about any prescription or over-the-counter medication and we check it for interactions with CoQ10 + PQQ by Advance Physician Formulas — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of CoQ10 + PQQ by Advance Physician Formulas
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains two active ingredients: ubiquinol (coenzyme Q10), a compound your cells use for energy and protection, and pyrroloquinoline quinone disodium salt, a cofactor also involved in cellular energy. The inactive ingredients are rice flour, hypromellose, magnesium stearate, silicon dioxide, and nicotinamide.
Does it work?
Strong evidence
Ubiquinol (CoQ10) is likely effective for coenzyme Q10 deficiency. It's possibly effective for fibromyalgia, migraine headache, congestive heart failure, and diabetic neuropathy based on the evidence we've reviewed.
We hold no effectiveness data for pyrroloquinoline quinone disodium salt.
How safe is it?
Well-documented data
CoQ10 is generally well tolerated by most adults at recommended doses. The most common side effects are gastrointestinal—appetite loss, diarrhea, heartburn, nausea, and vomiting—though these occur in less than 1% of people.
Headache, dizziness, and insomnia have been reported. Skin itching and allergic rash are rare.
Dividing doses above 100 mg daily may reduce stomach upset. We don't have enough safety data during pregnancy to say whether CoQ10 is safe, so the recommendation is to avoid it unless your doctor advises otherwise.
Safety while breastfeeding hasn't been well studied—use caution and talk with your doctor before starting.
Meds to double-check
Moderate interaction found
Before you start, double-check with your pharmacist if you take warfarin (Coumadin) or other blood thinners, chemotherapy drugs (especially alkylating agents like cyclophosphamide), or blood pressure medications. We couldn't check the PQQ ingredient for interactions, so run your full medication list through the tool on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
CoQ10 + PQQ may help if you have a CoQ10 deficiency, fibromyalgia, migraines, or heart or nerve issues, though evidence is stronger for some conditions than others. If you take warfarin, chemotherapy drugs, or blood pressure medications, check with your pharmacist before starting—these interactions could affect how your drugs work.
Talk to your doctor or pharmacist about whether this product fits your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CoQ10 + PQQ, straight from the product label.
| Brand | Advance Physician Formulas |
|---|---|
| Barcode (UPC) | 896996000694 |
| Net contents | 30 Vegetable Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2025 |
| DSLD ID | 337929 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other |
| Intended target group(s) | Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CoQ10 + PQQ by Advance Physician Formulas, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Pyrroloquinoline Quinone Disodium Salt | 20 mg | -- |
| Ubiquinol | 100 mg | -- |
Other ingredients: Rice Flour, Hypromellose, Magnesium Stearate, Silicon Dioxide, Nicotinamide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Coenzyme Q10 (COQ10) is an antioxidant produced by the body. It plays a key role in converting food into energy. Pyrroloquinoline Quinone (PQQ), also called methoxatin, is a redox cofactor and antioxidant.
CoQ10+PQQ 100 mg Ubiquinol per serving
Precautions
Warnings: For adults only. Keep out of reach of children.
Consult with a qualified healthcare professional prior to taking this product especially if you are pregnant, nursing, have a diagnosed medical condition, or are taking a prescription medication.
Sealed for your protection. Do not use if seal is missing or broken.
This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten. Produced in an FDA-registered, third-party audited, and cGMP-compliant facility that may process other products that contain these allergens or ingredients.
Storage
Store at room temperature, in a dry place. Protect product from excessive heat, freezing, humidity, and light.
Formulation
This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten.
Vcaps Plus
Brand IP Statement(s)
Vcaps is a trademark of Lonza or its affiliates.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, healthy adults take one capsule daily with food or as recommended by a qualified healthcare professional.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CoQ10 + PQQ by Advance Physician Formulas label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CoQ10 + PQQ by Advance Physician Formulas
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Pyrroloquinoline Quinone Disodium Salt
Ubiquinol
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Ubiquinol monograph & interactionsOther (inactive) ingredients: Rice Flour, Hypromellose, Magnesium Stearate, Silicon Dioxide, Nicotinamide. These complete the product’s ingredient list but are not active constituents.
CoQ10 + PQQ by Advance Physician Formulas Drug Interactions
HelloPharmacist Interaction Report
CoQ10 + PQQ by Advance Physician Formulas contains ubiquinol (a form of coenzyme Q10), which interacts with several medication types.
The most serious concern is with chemotherapy drugs called alkylating agents—CoQ10's antioxidant effects may theoretically reduce how well these drugs work by protecting cancer cells from the oxidative stress that makes chemotherapy effective. This is a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
Warfarin (Coumadin), a blood thinner, is also a Moderate concern. CoQ10 is structurally similar to vitamin K and may have blood-clotting effects that reduce warfarin's ability to prevent clots.
A small number of cases of reduced warfarin effectiveness have been reported. Blood pressure medications are a Minor interaction—CoQ10 might add to their blood-pressure-lowering effect, though study results have been mixed.
We could not check pyrroloquinoline quinone disodium salt (PQQ) for drug interactions because we hold no data on it. Use the medication checker on this page with your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CoQ10 + PQQ?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CoQ10 + PQQ interact with 198 drugs. Click any drug to see the details.
1 of the 2 ingredients in CoQ10 + PQQ interact with drugs. Each result below shows which ingredient is responsible. Ubiquinol
AltretamineHexalen
How Altretamine interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Altretamine interactionBendamustineBelrapzo, Treanda, Vivimusta
How Bendamustine interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Bendamustine interactionBendamustine HydrochlorideBendeka
How Bendamustine Hydrochloride interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Bendamustine Hydrochloride interactionBusulfanBusulfex, Myleran
How Busulfan interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Busulfan interactionCarboplatinParaplatin
How Carboplatin interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Carboplatin interactionCarmustineBiCNU, Gliadel, Gliadel Wafer
How Carmustine interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Carmustine interactionChlorambucilLeukeran
How Chlorambucil interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Chlorambucil interactionCisplatinPlatinol-AQ
How Cisplatin interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Cisplatin interactionCyclophosphamideCytoxan, Neosar
How Cyclophosphamide interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Cyclophosphamide interactionDacarbazineDTIC-Dome
How Dacarbazine interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Dacarbazine interactionEstramustine Phosphate SodiumEmcyt
How Estramustine Phosphate Sodium interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Estramustine Phosphate Sodium interactionIfosfamideIfex
How Ifosfamide interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Ifosfamide interactionLomustineCeenu
How Lomustine interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Lomustine interactionLurbinectedinZepzelca
How Lurbinectedin interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Lurbinectedin interactionMechlorethamine HydrochlorideValchlor
How Mechlorethamine Hydrochloride interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Mechlorethamine Hydrochloride interactionMelphalanAlkeran, Hepzato
How Melphalan interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Melphalan interactionMelphalan FlufenamidePepaxto
How Melphalan Flufenamide interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Melphalan Flufenamide interactionMelphalan HydrochlorideEvomela
How Melphalan Hydrochloride interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Melphalan Hydrochloride interactionOxaliplatinEloxatin
How Oxaliplatin interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Oxaliplatin interactionProcarbazineMatulane
How Procarbazine interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Procarbazine interactionStreptozocinZanosar
How Streptozocin interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Streptozocin interactionTemozolomideTemodar
How Temozolomide interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Temozolomide interactionThiotepaTepadina, Thioplex
How Thiotepa interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Thiotepa interactionTrabectedinYondelis
How Trabectedin interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAlkylating Agents Moderate
Interaction Summary
Coenzyme Q10 has antioxidant effects.
Read the full Ubiquinol + Trabectedin interactionWarfarinWarfarin
How Warfarin interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Ubiquinol + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolWarfarin (coumadin) Moderate
Interaction Summary
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Read the full Ubiquinol + Warfarin Sodium interactionAcebutololRhotral, Sectral
How Acebutolol interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Acebutolol interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Acetazolamide interactionAliskirenTekturna
How Aliskiren interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Aliskiren interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with CoQ10 + PQQ — through 1 ingredient. Tap an ingredient for the detail:
UbiquinolAntihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Ubiquinol + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CoQ10 + PQQ with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Ubiquinol
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for CoQ10 + PQQ, from the product label.
Advance Physician Formulas
See all Advance Physician Formulas products- Name
- Advance Physician Formulas Inc.
- Street Address
- 17165 Von Karman Avenue, Suite 109
- City
- Irvine
- State
- California
- ZipCode
- 92614
- Web Address
- physicianformulas.com
CoQ10 + PQQ by Advance Physician Formulas: Common Questions
Does CoQ10 + PQQ by Advance Physician Formulas interact with any medications?
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What's the difference between the two ingredients in this product?
Will this give me stomach problems?
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Is CoQ10 proven to work for heart problems?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CoQ10 + PQQ is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CoQ10 + PQQ’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
CoQ10 + PQQ's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
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