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Dietary supplement

Tongkat Ali 200 mg Ingredients & Drug Interactions

by Advance Physician Formulas

Tongkat Ali 200 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tongkat Ali 200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tongkat Ali 200 mg is a dietary supplement by Advance Physician Formulas with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tongkat Ali root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Tongkat Ali 200 mg by Advance Physician Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Tongkat Ali 200 mg by Advance Physician Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Tongkat Ali 200 mg by Advance Physician Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Tongkat Ali root extract at 200 mg per capsule. Tongkat Ali is a plant extract traditionally used in Southeast Asia, and this formulation uses the root portion.

The capsule itself is made with cellulose, a common inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: General tonic and traditional herbal support.
  • We looked for evidence on: Energy, Vitality, Stamina, Wellness.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Tongkat Ali shows possibly effective evidence for sexual desire — some research supports its use for libido. For athletic performance, the evidence points toward possibly ineffective.

The data we hold rates it insufficient to judge for back pain, osteoporosis, and diabetes, meaning studies haven't yet established whether it works for those uses.

The evidence, ingredient by ingredient Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term studies suggest Tongkat Ali is generally well tolerated, but long-term safety data and product quality aren't fully established. The supplement can raise testosterone levels, which carries a risk: if testosterone climbs beyond your normal range, you could see side effects like acne, insulin resistance, or liver stress.

Because of insufficient safety data and possible hormonal effects, the safety information advises against use during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this supplement, double-check if you're on propranolol — it's the biggest concern and can reduce how well the drug works. Also flag any medications that your liver breaks down using CYP1A2, CYP2C19, or CYP2A6 enzymes, and mention testosterone replacement therapy or supplements.

Use the medication checker below with your exact drug names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Tongkat Ali may be worth considering if you're interested in sexual desire support and have no drug interactions of concern. If you take propranolol or any other regular medications, check with us first — especially heart or blood pressure drugs.

Anyone pregnant, breastfeeding, or concerned about testosterone effects should talk with their pharmacist or doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tongkat Ali 200 mg, straight from the product label.

Brand Advance Physician Formulas
Barcode (UPC) 896996000106
Net contents 60 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 337947
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tongkat Ali 200 mg by Advance Physician Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
896996000106
IngredientAmount% DV
Tongkat Ali root extract200 mg--

Other ingredients: Cellulose, Modified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Tongkat Ali (Eurycoma longifolia) is a shrubby tree native to Southeast Asia, Malaysia, and Indonesia. The root has been used in traditional herbalism as a general tonic.

Tongkat Ali 200 mg per serving

Precautions

Warnings: For adults only. Keep out of reach of children.

Consult with a qualified healthcare professional prior to taking this product especially if you are pregnant, nursing, have a diagnosed medical condition, or are taking prescription medication.

Sealed for your protection. Do not use if seal is missing or broken.

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten. Produced in an FDA-registered, third-party audited, and cGMP-compliant facility that may process other products contain these allergens or ingredients.

Storage

Store at room temperature, in a dry place. Protect product from excessive heat, freezing, humidity, and light.

Formulation

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, sesame, or gluten.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, healthy adults take one capsule in the morning with or without food or as recommended by a qualified healthcare professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tongkat Ali 200 mg by Advance Physician Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tongkat Ali 200 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tongkat Ali 200 mg by Advance Physician Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Tongkat Ali root extract

Interacts with
248 drugs
200 mg per serving

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

Tongkat Ali root extract monograph & interactions

Other (inactive) ingredients: Cellulose, Modified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tongkat Ali 200 mg by Advance Physician Formulas Drug Interactions

Want to check YOUR meds against Tongkat Ali 200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
3 Moderate 245 Minor

Ingredients driving the most interactions

Tongkat Ali root extract 248

Individual Drug Interactions

The ingredients in Tongkat Ali 200 mg interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in Tongkat Ali 200 mg interact with drugs. Each result below shows which ingredient is responsible. Tongkat Ali root extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Tongkat Ali 200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Tongkat Ali root extract5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
Tongkat Ali root extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tongkat Ali 200 mg, from the product label.

Advance Physician Formulas

See all Advance Physician Formulas products
Name
Advance Physician Formulas, Inc.
Street Address
17165 Von Karman Ave. Suite 109
City
Irvine
State
CA
ZipCode
92614
Web Address
physicianformulas.com
Pharmacist Counseling Corner

Tongkat Ali 200 mg by Advance Physician Formulas: Common Questions

Does Tongkat Ali 200 mg by Advance Physician Formulas interact with any medications?
Yes. Based on its ingredients, Tongkat Ali 200 mg has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tongkat Ali 200 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Tongkat Ali actually work for sexual desire?
Research rates it possibly effective for sexual desire, so there is evidence behind it — though like many supplements, results vary person to person. This is the use with the strongest backing in our data.
Can I take this while pregnant or breastfeeding?
No. There isn't enough safety data during pregnancy, and the possible hormonal effects mean the safety information advises against it. Same goes for breastfeeding — talk with your doctor or pharmacist if you're considering it.
What are the side effects I should watch for?
If your testosterone levels climb too high, you might experience acne, insulin resistance, or liver stress. Short-term studies show it's generally well tolerated, but long-term safety data aren't fully available yet.
Is this safe to take long-term?
The research we have covers short-term use and shows it's generally tolerated, but long-term safety data and product quality consistency haven't been established — that's worth discussing with your pharmacist.
What is Tongkat Ali and where does it come from?
Tongkat Ali is a plant extract from Southeast Asia, traditionally used as a botanical supplement. This product uses the root portion in extract form at 200 mg per capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tongkat Ali 200 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tongkat Ali 200 mg label
Go deeper

The Full Monographs Behind Tongkat Ali 200 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eurycoma Longifolia

Interacts with 248 drugs

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....

Read the full Eurycoma Longifolia monograph →
Sources

Sources & How We Checked

Tongkat Ali 200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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