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Dietary supplement

Lobelia Ingredients & Drug Interactions

by Herb Pharm

Lobelia label
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Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lobelia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lobelia is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for asthma and breathing problems, cough and bronchitis, smoking cessation aid.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lobelia Aerial Parts, Seed Extract, Fresh, Undried. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lobelia by Herb Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Lobelia by Herb Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lobelia by Herb Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This liquid extract contains one active ingredient: lobelia aerial parts and seed, fresh and undried. The preparation is made with cane alcohol, distilled water, and vinegar as inactive ingredients.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: respiratory support and smoking cessation.
  • We looked for evidence on: Smoking cessation, breathing support, bronchial health, cough relief.
  • The closest evidence on file: Lobelia is rated "Possibly Ineffective" for Smoking cessation (Natural Medicines).

Lobelia is rated possibly ineffective for smoking cessation in our data. That means the evidence doesn't support its use for quitting smoking.

The evidence, ingredient by ingredient Lobelia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lobelia is a plant that demands caution — it can be toxic, especially at higher doses. You might experience nausea, vomiting, diarrhea, coughing, dizziness, tremors, or throat irritation even at doses as low as 50 mg.

At 600 mg or higher, toxicity symptoms can include sweating, rapid heartbeat, seizures, abnormally low body temperature, dangerously low blood pressure, coma, or death. The safety data advises against use during pregnancy and while breastfeeding due to toxicity concerns and lack of safety information.

Side effects, ingredient by ingredient Lobelia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lobelia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium, you must check with your pharmacist first — lobelia may raise lithium levels in your blood and require a dose change.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Lobelia is a powerful plant extract with significant toxicity risk at higher doses. If you take lithium, your doctor may need to adjust your dose before you start this product.

Because of the serious safety concerns, talk with your pharmacist before using it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lobelia, straight from the product label.

Brand Herb Pharm
Barcode (UPC) 090700001827
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 307603
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lobelia by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.44 mL
Maximum serving Sizes:
0.44 mL
Servings per container
272
UPC/BARCODE
090700001827
IngredientAmount% DV
Lobelia Aerial Parts, Seed Extract, Fresh, Undried415 mg--

Other ingredients: Cane Alcohol, Water, Distilled, Vinegar

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Shake well before using Adults: Add 0.44 ml (20 drops) to 2 oz. of water or juice, 1 to 4 times per day. Best taken between meals.

Precautions

Caution: Do not take drops undiluted. Do not exceed recommended serving.

Seek expert medical advice before taking during pregnancy.

Keep out of the reach of children

Storage

Store away from heat & light

Formula

Lobelia inflata

Lobelia liquid extract

We prepare our Lobelia Extract from the fresh (undried) aerial parts & seed of certified organic Lobelia inflata plants.

Formulation

System restoration Musculoskeletal

Gluten-free

Certified organic by Organic Certifiers

Seals/Symbols

USDA Organic

FDA Statement of Identity

Herbal Supplement

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lobelia by Herb Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lobelia label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lobelia by Herb Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.44 mL Dosage formLiquid Servings per container272 Amounts shown are per serving.

Lobelia Aerial Parts, Seed Extract, Fresh, Undried

Interacts with
1 drug
415 mg per serving Form: Lobelia inflata Aerial Parts Extract, Fresh, Undried, Lobelia inflata Seed Extract, Fresh, Undried

Lobelia is a traditional herb once used for breathing problems and to help people quit smoking, but reliable evidence supporting these uses is lacking...

Lobelia Aerial Parts, Seed Extract, Fresh, Undried monograph & interactions

Other (inactive) ingredients: Cane Alcohol, Water, Distilled, Vinegar. These complete the product’s ingredient list but are not active constituents.

Interaction report

Lobelia by Herb Pharm Drug Interactions

Want to check YOUR meds against Lobelia?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Lobelia Aerial Parts, Seed Extract, Fresh, Undried 1

Individual Drug Interactions

The ingredients in Lobelia interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Lobelia interact with drugs. Each result below shows which ingredient is responsible. Lobelia Aerial Parts, Seed Extract, Fresh, Undried

Each ingredient & the kinds of drugs it affects

For each ingredient in Lobelia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lobelia Aerial Parts, Seed Extract, Fresh, Undried1 drug type · 1 drug

Lithium

Lobelia is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, lobelia might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Lobelia Aerial Parts, Seed Extract, Fresh, Undried full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lobelia, from the product label.

Herb Pharm

See all Herb Pharm products
Name
Herb Pharm
City
Williams
State
OR
ZipCode
97544
Phone Number
800-348-4372
Web Address
www.herb-pharm.com
Pharmacist Counseling Corner

Lobelia by Herb Pharm: Common Questions

Does Lobelia by Herb Pharm interact with any medications?
Yes. Based on its ingredients, Lobelia has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lobelia contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this for smoking cessation?
The evidence doesn't support lobelia for quitting smoking — it's rated possibly ineffective for that use. You'd be better off discussing other options with your doctor or a smoking-cessation program.
What side effects might I experience?
Common effects include nausea, vomiting, diarrhea, coughing, dizziness, tremors, and throat irritation. These can happen even at low doses. Higher doses (600 mg or more) risk serious toxicity: rapid heartbeat, seizures, dangerously low blood pressure, and life-threatening symptoms.
Is it safe during pregnancy or breastfeeding?
No. The safety data advises against lobelia in both pregnancy and breastfeeding because of toxicity concerns and lack of safety information. Talk with your doctor if you're considering it.
What are the inactive ingredients?
This liquid extract uses cane alcohol, distilled water, and vinegar as its base — no other fillers or binders.
Why is caution so important with lobelia?
Lobelia can be toxic at higher doses. Symptoms of serious toxicity include sweating, rapid heartbeat, seizures, low body temperature, dangerously low blood pressure, coma, and even death. The margin between an active dose and a toxic one is narrow.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lobelia is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lobelia label
Go deeper

The Full Monographs Behind Lobelia’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lobelia

Interacts with 1 drug

Lobelia is a traditional herb once used for breathing problems and to help people quit smoking, but reliable evidence supporting these uses is lacking. It can be toxic in higher amounts, cau...

Read the full Lobelia monograph →
Sources

Sources & How We Checked

Lobelia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lobelia 6 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. McChargue DE, Collins FL Jr, Cohen LM. Effect of non-nicotinic moist snuff replacement and lobeline on withdrawal symptoms during 48-h smokeless tobacco deprivation. Nicotine Tob Res 2002;4:195-200. PubMed
  5. Stead LF, Hughes JR. Lobeline for smoking cessation. Cochrane Database Syst Rev 2000;2:CD000124. PubMed
  6. Plakun, A. L., Ambrus, J., Bross, I., Graham, S., Levin, M. L., and Ross, C. A. Clinical factors in smoking withdrawal: preliminary report. Am J Public Health Nations.Health 1966;56(3):434-441. PubMed

See these in context on the Lobelia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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