Longjack Extract 1000 mg Veg Capsules Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Longjack Extract 1000 mg Veg Capsules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Longjack Extract 1000 mg Veg Capsules is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eurycoma Longjack root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Longjack Extract 1000 mg Veg Capsules by BulkSupplements.com
Ask about any prescription or over-the-counter medication and we check it for interactions with Longjack Extract 1000 mg Veg Capsules by BulkSupplements.com — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Longjack Extract 1000 mg Veg Capsules by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Eurycoma Longjack root extract at 1,000 mg per capsule. The capsule itself is made from hypromellose, a plant-based capsule material.
Does it work?
Moderate evidence
The evidence we hold shows Longjack is possibly effective for sexual desire. For athletic performance, the evidence suggests it is possibly ineffective.
For back pain, osteoporosis, and diabetes, there is insufficient reliable evidence to rate whether it works — we simply don't have enough data on those uses.
How safe is it?
Well-documented data
Longjack is generally tolerated in short-term studies, but long-term safety and the quality of different products are uncertain. Because the extract can raise testosterone levels, there is a risk of testosterone-related side effects if your levels go above normal — including acne, insulin resistance, and liver effects.
The product is not recommended during pregnancy or while breastfeeding due to lack of safety data and possible hormonal effects.
Meds to double-check
Moderate interaction found
Before you take this product, double-check propranolol (Inderal) and any other heart or blood pressure medications with your pharmacist — the extract can reduce how well propranolol works. You should also verify any medications processed by your liver's CYP1A2, CYP2C19, or CYP2A6 enzymes, and any testosterone replacement therapy.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Longjack may be worth considering if you're interested in sexual desire support, but it does interact significantly with propranolol and potentially with several other medications. If you take any heart, blood pressure, or liver medications, or testosterone products, talk to your pharmacist before starting.
Definitely check your exact medications with the tool on this page.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Longjack Extract 1000 mg Veg Capsules, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Barcode (UPC) | X003GSRP75 |
| Net contents | 120 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2024 |
| DSLD ID | 312920 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Longjack Extract 1000 mg Veg Capsules by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Eurycoma Longjack root extract | 1000 mg | -- |
Other ingredients: Hypromellose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Longjack Extract Veg Capsules 1000 mg per serving
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 2 capsules daily, or as directed by a physician.
FDA Disclaimer Statement
Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
Always consult a physician before taking any dietary supplement.
Free of: Added sugar, soy, dairy, yeast, gluten, additives
Precautions
Keep out of reach of children.
Storage
Store in a dry, cool place
General Statements
New Scan Me
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Longjack Extract 1000 mg Veg Capsules by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Longjack Extract 1000 mg Veg Capsules by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Veg Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Eurycoma Longjack root extract
Interacts with248 drugs
Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...
Eurycoma Longjack root extract monograph & interactionsOther (inactive) ingredients: Hypromellose. These complete the product’s ingredient list but are not active constituents.
Longjack Extract 1000 mg Veg Capsules by BulkSupplements.com Drug Interactions
HelloPharmacist Interaction Report
Longjack Extract 1000 mg by BulkSupplements.com contains one active ingredient — Eurycoma Longjack root extract — which does interact with medications.
The most serious interaction is with propranolol (Inderal), a heart and blood pressure medication. Taking this product with propranolol can reduce propranolol's blood levels and effectiveness; a clinical study found that the extract lowered propranolol exposure by about 29%.
Read the full breakdown — every affected drug type, severity by severity
The extract also has minor theoretical interactions with several enzyme systems in your liver (CYP1A2, CYP2C19, and CYP2A6 substrates), which could potentially raise levels of drugs processed through those pathways — though this has not been confirmed in humans. Additionally, because Longjack may increase testosterone levels, there is a minor theoretical concern if you're taking testosterone replacement therapy or related hormones.
Altogether, these interactions span 248 individual medications. Use the medication checker on this page to search your exact drugs before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Longjack Extract 1000 mg Veg Capsules?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Longjack Extract 1000 mg Veg Capsules interact with 248 drugs. Click any drug to see the details.
1 of the 1 ingredient in Longjack Extract 1000 mg Veg Capsules interact with drugs. Each result below shows which ingredient is responsible. Eurycoma Longjack root extract
Hydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Eurycoma Longjack Root Extract + Hydrochlorothiazide, Propranolol interactionPropranololAngilol, Bedranol SR, Beta Prograne, Half Beta Prograne, Half-Inderal LA, Inderal +6 more
How Propranolol interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Eurycoma Longjack Root Extract + Propranolol interactionPropranolol HydrochlorideHemangeol
How Propranolol Hydrochloride interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractPropranolol (inderal), Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
Read the full Eurycoma Longjack Root Extract + Propranolol Hydrochloride interactionAbrocitinibCibinqo
How Abrocitinib interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Eurycoma Longjack Root Extract + Abrocitinib interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Longjack Extract 1000 mg Veg Capsules — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma Longjack Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longjack Root Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Longjack Extract 1000 mg Veg Capsules with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Eurycoma Longjack root extract
Propranolol (Inderal)
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.
Testosterone
Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.
Brand information
Manufacturer and brand details for Longjack Extract 1000 mg Veg Capsules, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Longjack Extract 1000 mg Veg Capsules by BulkSupplements.com: Common Questions
Does Longjack Extract 1000 mg Veg Capsules by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will Longjack help with sexual function?
Can I take this if I'm pregnant or breastfeeding?
What are the main side effects I should watch for?
How long is it safe to take Longjack?
Does this product have any fillers or other inactive ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Longjack Extract 1000 mg Veg Capsules is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Longjack Extract 1000 mg Veg Capsules’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Longjack Extract 1000 mg Veg Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Eurycoma Longifolia 4 references
- Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
- Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
- Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
- Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent
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