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Dietary supplement

Lotus Leaf 4:1 Extract Powder Ingredients & Drug Interactions

by TerraVita Premium Collection

Lotus Leaf 4:1 Extract Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lotus Leaf 4:1 Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Lotus Leaf 4:1 Extract Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for digestive upset and diarrhea, anxiety and relaxation, sleep support.Based on those ingredients, 212 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lotus leaf extract powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Lotus Leaf 4:1 Extract Powder by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Lotus Leaf 4:1 Extract Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Lotus Leaf 4:1 Extract Powder by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: lotus leaf extract in a concentrated 4:1 form, meaning four pounds of fresh leaf material have been reduced to one pound of extract powder. Lotus leaf has a long history in traditional medicine and food use, particularly in East Asian cuisines where it's eaten as a vegetable and brewed as a tea.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Lotus product and its label doesn't state a use — see Lotus's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold shows insufficient reliable evidence to rate lotus leaf for any of its traditional uses — nausea and vomiting, sore throat, insomnia, weight management, heavy menstrual bleeding, and bleeding support all fall into that category. That doesn't mean it doesn't work; it means rigorous human trials haven't yet been done or published on most of these claims.

The evidence, ingredient by ingredient Lotus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lotus is common as food, but supplement safety hasn't been well studied in humans at medicinal doses. The safety data advises against using concentrated supplements like this one.

Allergic reactions including hives and contact dermatitis have been reported, including in a case of a young child who developed hives after eating lotus root. There isn't enough safety data to know whether it's safe during breastfeeding — talk with your doctor or pharmacist before use if you're nursing.

Side effects, ingredient by ingredient Lotus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lotus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 212 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs like warfarin, aspirin, or clopidogrel (Moderate risk of bleeding). Also flag it if you take antidiabetes medications (Moderate risk of low blood sugar) or pentobarbital (Moderate risk of extra drowsiness).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Lotus Leaf 4:1 Extract Powder may appeal to you if you're exploring traditional botanical support, but the evidence for its effectiveness isn't established in our data. More importantly, it interacts with blood thinners, diabetes drugs, and barbiturate sedatives — if you take any of those, run your medications through our checker before starting.

Check with your own doctor or pharmacist to see whether this product fits your health situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lotus Leaf 4:1 Extract Powder, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435207199
Net contents 4 Ounce(s)
Market status On market
Date entered into DSLD Apr 21, 2023
DSLD ID 289751
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lotus Leaf 4:1 Extract Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.25 Teaspoon(s)
Servings per container
113
UPC/BARCODE
064435207199
IngredientAmount% DV
Lotus leaf extract powder1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lotus Leaf 4:1 Extract Powder by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lotus Leaf 4:1 Extract Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lotus Leaf 4:1 Extract Powder by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container113 Amounts shown are per serving.

Lotus leaf extract powder

Interacts with
212 drugs
1000 mg per serving

Lotus is an edible aquatic plant used in food and traditional medicine across Asia, with parts like the seeds, leaves, and flowers taken for digestion...

Lotus leaf extract powder monograph & interactions
Interaction report

Lotus Leaf 4:1 Extract Powder by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Lotus Leaf 4:1 Extract Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
212Drugs
212 Moderate

Ingredients driving the most interactions

Lotus leaf extract powder 212

Individual Drug Interactions

The ingredients in Lotus Leaf 4:1 Extract Powder interact with 212 drugs. Click any drug to see the details.

1 of the 1 ingredient in Lotus Leaf 4:1 Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Lotus leaf extract powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Lotus Leaf 4:1 Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lotus leaf extract powder3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concurrent use of lotus with other antiplatelet drugs might reduce platelet aggregation and increase the risk of bleeding.
Neferine and isoliensinine, constituents of lotus, have been shown to inhibit platelet aggregation, in vitro. These constituents can inhibit the production of pro-aggregating factors like prostaglandins.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lotus might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Animal research shows that the ethanolic extract of lotus reduces blood glucose levels and potentiates the effects of injected insulin. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, taking lotus concomitantly with pentobarbital might increase sedation.
Animal research shows that lotus extract increases pentobarbitone-induced sleeping time. It is not known if this occurs in humans or if this effect occurs with other barbiturates or sedatives.

Likelihood Possible Evidence D
Lotus leaf extract powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Lotus Leaf 4:1 Extract Powder, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Lotus Leaf 4:1 Extract Powder by TerraVita Premium Collection: Common Questions

Does Lotus Leaf 4:1 Extract Powder by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Lotus Leaf 4:1 Extract Powder has a known interaction with 212 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Lotus Leaf 4:1 Extract Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood thinner like warfarin?
No — not without talking to your doctor first. Lotus leaf can boost bleeding risk when combined with blood thinners or antiplatelet drugs because it contains compounds that reduce platelet clumping. Your doctor may need to monitor you closely or adjust your dose.
Can I use this if I have diabetes and take medication for it?
You'll need to check with your doctor. Lotus appears to lower blood glucose levels on its own, so taking it with diabetes drugs might drop your blood sugar too far. Close monitoring and a dose adjustment could be needed.
What are the side effects?
Allergic reactions including hives and contact dermatitis have been reported — including a case where a child developed hives after eating lotus root. Supplement safety in humans at medicinal doses hasn't been well studied, so other effects aren't fully known.
Is it safe to take while breastfeeding?
There isn't enough safety data to know either way. Talk with your doctor or pharmacist before using this product if you're nursing — they can help you weigh the unknowns.
Does this actually work for insomnia or weight loss?
The evidence isn't established in our data. Lotus has been used traditionally for both, but rigorous human studies aren't yet available to confirm whether it's effective for these purposes.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lotus Leaf 4:1 Extract Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lotus Leaf 4:1 Extract Powder label
Go deeper

The Full Monographs Behind Lotus Leaf 4:1 Extract Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lotus

Interacts with 212 drugs

Lotus is an edible aquatic plant used in food and traditional medicine across Asia, with parts like the seeds, leaves, and flowers taken for digestion, calm, and overall wellness. Most healt...

Read the full Lotus monograph →
Sources

Sources & How We Checked

Lotus Leaf 4:1 Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lotus 5 references
  1. Yu, J. and Hu, W. S. [Effects of neferine on platelet aggregation in rabbits]. Yao Xue.Xue.Bao. 1997;32(1):1-4.
  2. Yang, J. and Zhou, K. NMR spectroscopic analysis of neferine and isoliensinine. Magn Reson.Chem 2004;42(11):994-997. PubMed
  3. Mukherjee, P. K., Saha, K., Balasubramanian, R., Pal, M., and Saha, B. P. Studies on psychopharmacological effects of Nelumbo nucifera Gaertn. rhizome extract. J Ethnopharmacol. 1996;54(2-3):63-67. PubMed
  4. Mukherjee, P. K., Saha, K., Pal, M., and Saha, B. P. Effect of Nelumbo nucifera rhizome extract on blood sugar level in rats. J Ethnopharmacol. 1997;58(3):207-213. PubMed
  5. Hiraguchi Y, Tokuda R, Gen M, et al. Identification of a novel food allergen in lotus root. Allergol Int. 2018;67(1):141-143. PubMed

See these in context on the Lotus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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