Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

LTP Ingredients & Drug Interactions

by Ecological Formulas

LTP label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking LTP against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

LTP is a dietary supplement by Ecological Formulas with 2 active ingredients. Its ingredients are commonly taken for digestive support for protein digestion, wound cleaning (debridement of dead tissue), sore throat and inflammation.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Papain. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against LTP by Ecological Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with LTP by Ecological Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of LTP by Ecological Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

LTP contains two active ingredients: papain and ABGland Thymus. Papain is a protein-digesting enzyme from papaya; ABGland Thymus is a thymus gland extract.

The product also contains several inactive ingredients — beef tissue, microcrystalline cellulose, gelatin, dicalcium phosphate, soy lecithin, silicon dioxide, and magnesium stearate — which are fillers and capsule materials with no active role.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: thymic peptide immune support.
  • We looked for evidence on: immune function, thymic health, T-cell function.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence we hold doesn't establish that papain works for the uses listed on this product. For cancer, dental caries, radiation dermatitis, exercise-induced muscle soreness, shingles, and intestinal parasite infection, the data rates papain as having insufficient reliable evidence.

We hold no effectiveness information for ABGland Thymus.

The evidence, ingredient by ingredient Papain

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Papain is generally well tolerated as a food, but supplements may irritate your digestive tract or trigger allergic reactions — especially in people sensitive to it. Short-term use at normal doses appears safe, but high oral doses may not be.

Concentrated papain and unripe papaya products are not advised in pregnancy due to safety concerns. There isn't enough reliable safety information to recommend papain supplements while breastfeeding, so talk with your doctor or pharmacist if you're nursing.

If you're sensitive to papain, you may experience allergic symptoms like itchy watery eyes, runny nose, sneezing, stomach cramps, sweating, or diarrhea. Rare but serious effects at high doses include esophageal perforation and severe stomach inflammation.

Occupational exposure to papain dust can cause respiratory allergies.

Side effects, ingredient by ingredient Papain

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Papain.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin or any other blood thinner (anticoagulant), check with your doctor or pharmacist before starting this product — papain may increase the blood thinner's effect and raise your bleeding risk. We could not check the second ingredient, ABGland Thymus, for interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

The evidence doesn't establish that papain works for the conditions listed. If you take blood thinners like warfarin, check with your doctor or pharmacist before using this product — papain may increase warfarin's effect and bleeding risk.

If you're pregnant or breastfeeding, talk it over with your healthcare provider first. For anyone else, keep an eye out for digestive upset or allergic symptoms.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about LTP, straight from the product label.

Brand Ecological Formulas
Barcode (UPC) 696859131264
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 299778
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for LTP by Ecological Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
696859131264
IngredientAmount% DV
Papain30 mg--
ABGland Thymus600 mg--

Other ingredients: Beef Tissue, Microcrystalline Cellulose, Gelatin, Dicalcium Phosphate, Soy Lecithin, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Dietary Supplement

Formula

LTP is a scientifically-designed supplement containing thymulin, thymosin, thymolymphotropin, and other polypeptides, in a base of papain. These lyphoactivated thymic peptides are from bovine and are free of corn, yeast, and wheat.

Lyphoactivated Thymic Peptides 600 mg

Formulation

These lyphoactivated thymic peptides are from bovine and are free of corn, yeast, and wheat.

Suggested/Recommended/Usage/Directions

Directions Take one capsule daily, or as directed by a physician.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

LTP by Ecological Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

LTP label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in LTP by Ecological Formulas

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Papain

Interacts with
2 drugs
30 mg per serving

Papain is a protein-digesting enzyme from the papaya plant that is used in digestive supplements and some topical products. While it has clear food an...

Papain monograph & interactions

ABGland Thymus

600 mg per serving Form: Bovine

Other (inactive) ingredients: Beef Tissue, Microcrystalline Cellulose, Gelatin, Dicalcium Phosphate, Soy Lecithin, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

LTP by Ecological Formulas Drug Interactions

Want to check YOUR meds against LTP?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Moderate

Ingredients driving the most interactions

Papain 2

Individual Drug Interactions

The ingredients in LTP interact with 2 drugs. Click any drug to see the details.

1 of the 2 ingredients in LTP interact with drugs. Each result below shows which ingredient is responsible. Papain

Each ingredient & the kinds of drugs it affects

For each ingredient in LTP with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Papain1 drug type · 2 drugs

Warfarin (Coumadin)

Theoretically, papain might increase the effects and side effects of warfarin.
In one case report, a patient previously stable on warfarin was found to have an international normalization ratio (INR) of 7.4, which was attributed to ingestion of a supplement containing papain from papaya extract.

Likelihood Possible Evidence D
Papain full monograph & interactions
The maker

Brand information

Manufacturer and brand details for LTP, from the product label.

Ecological Formulas

See all Ecological Formulas products
Name
ECOLOGICAL FORMULAS
Street Address
1061-B SHARY CIRCLE
City
CONCORD
State
CA
ZipCode
94518
Pharmacist Counseling Corner

LTP by Ecological Formulas: Common Questions

Does LTP by Ecological Formulas interact with any medications?
Yes. Based on its ingredients, LTP has a known interaction with 2 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
LTP contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is papain safe if I'm pregnant?
Concentrated papain and unripe papaya products are not advised during pregnancy due to safety concerns. Talk with your doctor or pharmacist for personalized guidance before taking this product if you're pregnant.
Can I take this while breastfeeding?
There isn't enough reliable safety information to know whether supplemental papain is safe while breastfeeding. Check with your doctor or pharmacist to decide what's right for you and your baby.
What are the common side effects?
Papain may cause allergic reactions in sensitive people — itchy watery eyes, runny nose, sneezing, stomach cramps, sweating, or diarrhea. Supplements may also irritate your digestive tract. High doses are more likely to cause problems.
Does this product actually work for the conditions listed?
The evidence we hold doesn't establish that papain works for cancer, dental caries, radiation dermatitis, exercise soreness, shingles, or intestinal parasites. For all these uses, we have insufficient reliable evidence.
What is papain?
Papain is a protein-digesting enzyme (protease) from papaya fruit. It's used in some supplements and is generally well tolerated as a food, though supplements may irritate the digestive tract or cause allergic reactions in sensitive individuals.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if LTP is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

LTP label
Go deeper

The Full Monographs Behind LTP’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Papain

Interacts with 2 drugs

Papain is a protein-digesting enzyme from the papaya plant that is used in digestive supplements and some topical products. While it has clear food and laboratory uses, strong human evidence...

Read the full Papain monograph →
Sources

Sources & How We Checked

LTP's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Papain 11 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
  3. Shuttleworth D, Hill S, Marks R, Connelly DM. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents. Br J Dermatol 1988;119:535-40.
  4. Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
  5. Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
  6. Walker-Renard, P. Update on the medicinal management of phytobezoars. Am J Gastroenterol. 1993;88(10):1663-1666.
  7. Tymoszuk D, Wiszniewska M, Walusiak-Skorupa J. Papain-induced occupational rhinoconjunctivitis and asthma - A case report. Med Pr 2016;67(1):109-12. PubMed
  8. Soto-Mera MT, López-Rico MR, Filgueira JF, et al. Occupational allergy to papain. Allergy 2000;55(10):983-4. PubMed
  9. Tarlo SM, Shaikh W, Bell B, et al. Papain-induced allergic reactions. Clin Allergy 1978;8(3):207-15. PubMed
  10. Baur X, König G, Bencze K, Fruhmann G. Clinical symptoms and results of skin test, RAST and bronchial provocation test in thirty-three papain workers: Evidence for strong immunogenic potency and clinically relevant proteolytic e?ects of airborne papain. C
  11. Novey HS, Keenan WJ, Fairshter RD, Wells ID, Wilson AF, Culver BD. Pulmonary disease in workers exposed to papain: clinico-physiological and immunological studies. Clin Allergy 1980;10(6):721-31. PubMed

See these in context on the Papain monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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