No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Macagen Ingredients & Drug Interactions

by Genestra Brands

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Macagen is a dietary supplement by Genestra Brands with 1 active ingredient. Its ingredients are commonly taken for low libido and sexual function, energy and stamina, menopause symptoms.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Macagen by Genestra Brands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Macagen contains one active ingredient: maca root extract (Lepidium meyenii). Maca is a Peruvian plant traditionally used as a food and supplement, though what it does in the body and how well it works aren't yet well established by research.

The capsule itself is made from hypromellose and cellulose, both inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Maca product and its label doesn't state a use — see Maca's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for maca root extract isn't established in the data we hold. The studies we have give us insufficient reliable evidence to rate it for amenorrhea (absent periods), anemia, antidepressant-related sexual dysfunction, athletic performance, or osteoporosis.

That doesn't mean it doesn't work—it means we don't yet have enough solid data to say either way.

The evidence, ingredient by ingredient Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Maca root extract is generally well tolerated when eaten as a food, but long-term safety as a supplement hasn't been studied carefully. The safety data during pregnancy and breastfeeding is too thin to know either way, so the safety guidance is to avoid it in both cases.

Fresh, uncooked maca may cause stomach pain in some people; the extract in this product is processed, but it's something to be aware of.

Side effects, ingredient by ingredient Maca

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the active ingredient in Macagen. That said, use the medication checker on this page with your full list before you start, and talk to your pharmacist or doctor if you're unsure.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Macagen may be worth considering if you're looking to try maca for a specific reason and you've talked it over with your doctor or pharmacist. Because we don't have long-term safety data for it as a supplement, and because it's not recommended in pregnancy or while breastfeeding, those are conversations to have before you start.

Check with your own healthcare provider about whether it makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Macagen, straight from the product label.

Brand Genestra Brands
Barcode (UPC) 883196112012
Net contents 180 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 231371
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Macagen by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
UPC/BARCODE
883196112012
IngredientAmount% DV
Maca (Lepidium meyenii) root extract430 mg--

Other ingredients: Hypromellose, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended dose: Take 1 capsule 2 times daily or as recommended by your health professional.

Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our quality excellence

FDA Statement of Identity

Dietary Supplement

Formulation

Traditional support for emotional well-being and sexual health

See for yourself

Macagen by Genestra Brands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Macagen by Genestra Brands

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

430 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca (Lepidium meyenii) root extract monograph & interactions

Other (inactive) ingredients: Hypromellose, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Macagen by Genestra Brands Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Macagen. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Macagen, from the product label.

Genestra Brands

Name
Seroyal USA
City
Pittsburgh
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Web Address
seroyal.com
Pharmacist Counseling Corner

Macagen by Genestra Brands: Common Questions

Does Macagen by Genestra Brands interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Macagen. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Macagen contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is maca safe to take if I'm pregnant or breastfeeding?
The safety data isn't there yet, so the guidance is to avoid it during both pregnancy and breastfeeding. Talk with your doctor about your options if you're in either situation.
Will this give me an upset stomach?
The extract in Macagen is processed, but fresh, uncooked maca can cause stomach pain. If you're sensitive to supplements, start low and see how you feel.
What is maca root used for?
Maca is a plant from Peru traditionally used as both a food and supplement. We don't yet have solid evidence it works for amenorrhea, anemia, sexual dysfunction related to antidepressants, athletic performance, or osteoporosis.
Is this safe to take long term?
Maca is generally well tolerated as a food, but long-term safety as a supplement hasn't been studied. Talk with your pharmacist about how long you plan to use it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Macagen is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Macagen label
Go deeper

The Full Monographs Behind Macagen’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Macagen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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