No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Macagen Ingredients & Drug Interactions

by Genestra Brands

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Macagen is a dietary supplement by Genestra Brands with 1 active ingredient. Its ingredients are commonly taken for low libido and sexual function, energy and stamina, menopause symptoms.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Macagen by Genestra Brands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Macagen is a single-ingredient product: maca root extract (Lepidium meyenii), a plant native to Peru traditionally used in foods and herbal preparations. The supplement also contains two inactive ingredients — hypromellose and cellulose — which are common capsule binders and fillers.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: sexual function and energy support.
  • We looked for evidence on: Sexual desire, Antidepressant-induced sexual dysfunction, Fatigue, Chronic fatigue syndrome (CFS), Athletic performance, libido — and 2 related terms.
  • The closest evidence on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Antidepressant-induced sexual dysfunction (Natural Medicines).
  • Also on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Chronic fatigue syndrome (CFS), Fatigue, Sexual desire.

The evidence we hold on maca for its various proposed uses — including amenorrhea (absent menstrual periods), anemia, sexual dysfunction tied to antidepressants, athletic performance, and bone health — is insufficient to rate how well it works. That means the science hasn't yet established clear benefit for these purposes.

If you're considering it for a specific reason, it's worth talking that through with your doctor or pharmacist.

The evidence, ingredient by ingredient Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Maca is generally well tolerated when used as a food, but long-term safety as a supplement hasn't been studied extensively. Raw, uncooked maca may cause stomach pain in some people.

The safety data during pregnancy is not sufficient to recommend use — talk with your doctor or pharmacist before taking it if you're pregnant or nursing.

Side effects, ingredient by ingredient Maca

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the maca in this product. That doesn't mean interactions can't happen — it means the science we hold doesn't flag any.

If you're on any medications and want to be sure, talk it over with your pharmacist.

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Macagen is a straightforward maca supplement with no documented medication interactions. However, because long-term supplement safety data on maca is limited and evidence for its benefits isn't established, it's best to discuss whether it makes sense for you with your own doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Macagen, straight from the product label.

Brand Genestra Brands
Barcode (UPC) 88319613090
Net contents 60 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2016
DSLD ID 55992
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Macagen by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
88319613090
IngredientAmount% DV
Maca (Lepidium meyenii) root extract430 mg--

Other ingredients: Hypromellose, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Dose: Take one capsule two times daily or as recommended by your healthcare practitioner.

Precautions

Risk Information: If you are pregnant or breastfeeding; if you have high blood pressure or suffer from any psychological disorder or condition such as frequent anxiety or depression or if you are taking blood thinners or antidepressants, consult your healthcare practitioner prior to use.

Quality Assurance: Safety-sealed for your protection and for product freshness. Do not use if outer seal is missing or broken.

General

439

FDA Statement of Identity

HERBAL SUPPLEMENT

Seals/Symbols

Seroyal

Formulation

Guaranteed to contain no added wheat, starch, yeast, gluten, corn, soy, sodium, sugar, artificial coloring or flavoring, antimicrobial preservatives, dairy or animal products.

Ideal for vegans.

The capsules are made from 100% pure vegetable sources, free of preservatives and additives.

Storage

Store in a cool, dry place.

See for yourself

Macagen by Genestra Brands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Macagen by Genestra Brands

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

430 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca (Lepidium meyenii) root extract monograph & interactions

Other (inactive) ingredients: Hypromellose, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Macagen by Genestra Brands Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Macagen. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Macagen, from the product label.

Genestra Brands

Name
Seroyal USA
City
Pittsburgh
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Web Address
seroyal.com
Pharmacist Counseling Corner

Macagen by Genestra Brands: Common Questions

Does Macagen by Genestra Brands interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Macagen. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Macagen contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will maca cause stomach problems?
Raw, uncooked maca may cause stomach pain in some people. This product is an extract, so the risk may be lower, but if you experience discomfort after taking it, stop and let your pharmacist know.
Is it safe to take Macagen while pregnant or breastfeeding?
The safety data isn't there for either pregnancy or breastfeeding — so it's best to avoid it during those times. Talk with your doctor or pharmacist if you're considering it.
Does maca actually work for low energy or sexual function?
The evidence we have is insufficient to say how well it works for those purposes or for any of the other uses people try it for. The science just hasn't settled the question yet.
How long has maca been studied as a supplement?
Maca has a long history as a food in Peru, but long-term safety data as a supplement in concentrated amounts is limited. That's why we can't fully vouch for safety over time.
Can I take Macagen with my prescription medications?
No interactions are documented in our data for maca, but that's not a guarantee none exist. Run your specific medications through the checker on this page, and if you want peace of mind, check with your own pharmacist before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Macagen is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Macagen label
Go deeper

The Full Monographs Behind Macagen’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Macagen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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