Interactions on record — worth a quick check against your medications. Based on 4 of 7 ingredients. Check your meds →
Dietary supplement

Magnify Ingredients & Drug Interactions

by Huge Nutrition

Magnify label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Magnify against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Magnify is a dietary supplement by Huge Nutrition with 7 active ingredients. Its ingredients are commonly taken for exercise performance, muscle soreness and fatigue, blood flow and circulation.Based on those ingredients, 1,156 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bioperine, Beet Root Extract, L-Arginine Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Magnify by Huge Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Magnify by Huge Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Magnify by Huge Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 6 of its 9 active ingredients.
  • “L-Arginine Complex” is a proprietary blend — the label gives one combined amount (1,500 mg) without saying how much of each component you get.

Magnify contains 9 ingredients total. The active ones are amino acids and plant extracts: three forms of L-arginine (plain, alpha-ketoglutarate, and hydrochloride), L-citrulline, L-norvaline, Bioperine (a black pepper extract), beet root extract, S7, and VAS06.

These work primarily to support nitric oxide production and blood vessel function. The inactive ingredients are gelatin (capsule), titanium dioxide, red and blue food dyes (FD&C Red #3 and Blue #1), magnesium stearate, and silicon dioxide.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: enhance nitric oxide production and muscle pumps.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle soreness, Erectile dysfunction (ED), Hypertension, blood flow, circulation — and 1 related terms.
  • The strongest evidence on file: Beet is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beet is rated "Possibly Effective" for Exercise-induced muscle soreness.
  • Also on file: L-citrulline is rated "Possibly Effective" for Athletic performance.

We hold effectiveness ratings only for L-citrulline and beet root extract. L-citrulline is possibly effective for athletic performance but possibly ineffective for sarcopenia; evidence is insufficient to rate it for cardiovascular disease, heart failure, Reye syndrome, or diabetes.

Beet root extract is possibly effective for athletic performance and exercise-induced muscle soreness but possibly ineffective for COPD; evidence is insufficient for dyslipidemia and cognitive function. No effectiveness data are on file for L-arginine (any form), L-norvaline, Bioperine, S7, or VAS06.

The evidence, ingredient by ingredient L-citrulline Black Pepper Beet L-arginine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-arginine is generally well tolerated short-term but can lower blood pressure and isn't safe for everyone—use only under medical supervision, and avoid it unless your doctor advises otherwise if you're unsure. Common side effects are abdominal pain, bloating, nausea, diarrhea, headache, insomnia, and flushing.

L-citrulline is generally well tolerated in healthy adults, with gastrointestinal discomfort and heartburn as the main side effects, though long-term safety isn't fully studied. Bioperine (black pepper) is generally safe in food amounts but concentrated supplements should be used cautiously; burning aftertaste, indigestion, and reduced taste perception are common.

Beet root extract is generally well tolerated and safe as a food but concentrated supplements lack safety data; red or black stools are common and harmless, though large amounts could theoretically cause low calcium or kidney damage. For pregnancy: L-arginine and L-arginine hydrochloride are possibly safe; L-citrulline and Bioperine safety data aren't on file, so talk with your doctor.

For breastfeeding: L-citrulline safety is unknown, so avoid supplemental use; Bioperine is likely safe; L-arginine and beet data aren't on file.

Side effects, ingredient by ingredient L-citrulline Black Pepper Beet L-arginine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Beet, Black Pepper, L-arginine, L-citrulline.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 1,157 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Magnify, check with your doctor or pharmacist if you take any blood pressure medications (Moderate), potassium-sparing water pills (Moderate), blood thinners or antiplatelet drugs (Moderate), diabetes medications (Moderate), ACE inhibitors or ARBs (Moderate), sildenafil or other PDE-5 inhibitors (Moderate), propranolol, phenytoin, theophylline, rifampin, nevirapine, cyclosporine, pentobarbital, or atorvastatin (all Moderate), or any medications metabolized by your liver's CYP3A4 enzyme system (Moderate). Even small doses of black pepper can significantly raise levels of some of these drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a nitric oxide–boosting supplement aimed at athletic performance and circulation, built on L-arginine and L-citrulline. It's best suited for people without heart disease, high blood pressure, diabetes, or bleeding disorders—and absolutely not for anyone on blood pressure meds, blood thinners, or diabetes drugs without clearing it with their doctor or pharmacist first.

The black pepper and beet extracts add extra medication interactions to watch for. Talk it over with your own healthcare provider before starting, especially if you take any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Magnify, straight from the product label.

Brand Huge Nutrition
Barcode (UPC) 728614780827
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 299812
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Magnify by Huge Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
UPC/BARCODE
728614780827
IngredientAmount% DV
L-Arginine0 NP--
L-Citrulline1000 mg--
Bioperine10 mg--
L-Norvaline300 mg--
L-Arginine Alpha-Ketoglutarate0 NP--
L-Arginine Hydrochloride0 NP--
Beet Root Extract1000 mg--
S7150 mg--
L-Arginine Complex1500 mg--
VAS06400 mg--

Other ingredients: Gelatin, Titanium Dioxide, FD&C Red #3, FD&C Blue #1, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Warning: For use by healthy adults only, not recommended for persons under the age of 18.

Do not use if you are pregnant or nursing.

Seek advice from a healthcare professional before taking if you have any preexisting medical condition to ensure it is safe to take this product. In case of accidental overdose, contact a poison control center immediately.

Keep out of the reach of children.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take six (6) capsules with 8-12 fl oz of water.

Seals/Symbols

Made in USA GMP Good Manufacturing Practice

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Advanced Nitric Oxide Formula Enhance N.O. Production Increase muscle pumps Explosive workouts

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Bioperine is a registered trademark of Sabinsa Corporation. S7 is a trademark of VDF FutureCeuticals, Inc, used under license. Vaso:6 is a registered trademark under exclusive global distribution by Compound Solutions, Inc.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Magnify by Huge Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Magnify label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Magnify by Huge Nutrition

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size6 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

L-Citrulline

Interacts with
178 drugs
1000 mg per serving

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...

L-Citrulline monograph & interactions

Bioperine

Interacts with
1,019 drugs
10 mg per serving Form: Black Pepper Fruit Extract

Black pepper is a common kitchen spice that is generally safe in the amounts used in food. Its extract, piperine, is mostly added to supplements to he...

Bioperine monograph & interactions

L-Norvaline

300 mg per serving

Beet Root Extract

Interacts with
861 drugs
1000 mg per serving Form: Betanin

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet Root Extract monograph & interactions

S7

150 mg per serving Form: Blueberry, Broccoli, Green Coffee bean extract, Green Tea extract, Kale, Tart Cherry, Turmeric extract

L-Arginine Complex

Interacts with
403 drugs
1500 mg per serving

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for bl...

L-Arginine Complex monograph & interactions

VAS06

400 mg per serving Form: Green Tea leaf extract

Other (inactive) ingredients: Gelatin, Titanium Dioxide, FD&C Red #3, FD&C Blue #1, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Magnify by Huge Nutrition Drug Interactions

Want to check YOUR meds against Magnify?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,156Drugs
1,110 Moderate 46 Minor

Ingredients driving the most interactions

Bioperine 1,019
Beet Root Extract 861
L-Arginine Complex 403
L-Citrulline 178

Individual Drug Interactions

The ingredients in Magnify interact with 1,156 drugs. Click any drug to see the details.

4 of the 7 ingredients in Magnify interact with drugs. Each result below shows which ingredient is responsible. Bioperine Beet Root Extract L-Arginine Complex L-Citrulline

Each ingredient & the kinds of drugs it affects

For each ingredient in Magnify with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bioperine17 drug types · 1,019 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, black pepper might increase the risk of bleeding when taken with antiplatelet or anticoagulant drugs.
In vitro research shows that piperine, a constituent of black pepper, seems to inhibit platelet aggregation. This has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, black pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that piperine, a constituent of black pepper, can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Atorvastatin (Lipitor)

Theoretically, black pepper might increase blood levels of atorvastatin.
Animal research shows that taking piperine, a constituent of black pepper, 35 mg/kg can increase the maximum serum concentration of atorvastatin three-fold. This has not been reported in humans.

Likelihood Possible Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, black pepper might increase the effects and side effects of cyclosporine.
In vitro research shows that piperine, a constituent of black pepper, increases the bioavailability of cyclosporine. This has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, black pepper might increase levels of drugs metabolized by CYP2D6.
In vitro research suggests that some constituents of black pepper inhibit CYP2D6. This has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, black pepper might increase levels of drugs metabolized by CYP3A4.
In vitro research and pharmacokinetic simulation data suggest that piperine, a constituent of black pepper, as well as the pepper fruit seem to inhibit CYP3A4. This has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, black pepper might increase blood levels of lithium due to its diuretic effects. The dose of lithium might need to be reduced.
Black pepper is thought to have diuretic properties.

Likelihood Probable Evidence D
Nevirapine (Viramune)

Black pepper might increase blood levels of nevirapine.
Clinical research shows that piperine, a constituent of black pepper, increases the plasma concentration of nevirapine. However, no adverse effects were observed in this study.

Likelihood Probable Evidence D
P-Glycoprotein Substrates

Theoretically, black pepper might increase levels of P-glycoprotein substrates.
In vitro research shows that piperine, a constituent of black pepper, seems to inhibit P-glycoprotein.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, black pepper might increase the sedative effects of pentobarbital.
Animal research shows that piperine, a constituent of black pepper, increases pentobarbital-induced sleeping time.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

Black pepper might increase blood levels of phenytoin.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption, slow elimination, and increase levels of phenytoin. Taking a single dose of black pepper 1 gram along with phenytoin seems to double the serum concentration of phenytoin. Consuming a soup with black pepper providing piperine 44 mg/200 mL of soup along with phenytoin also seems to increase phenytoin levels when compared with consuming the same soup without black pepper.

Likelihood Possible Evidence B
Propranolol (Inderal)

Black pepper might increase blood levels of propranolol.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of propranolol.

Likelihood Possible Evidence B
Rifampin (Rifadin)

Black pepper might increase blood levels of rifampin.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and serum levels of rifampin.

Likelihood Possible Evidence B
Theophylline

Black pepper might increase blood levels of theophylline.
Clinical research shows that piperine, a constituent of black pepper, seems to increase absorption and slow elimination of theophylline.

Likelihood Possible Evidence D
Amoxicillin (Amoxil, Trimox)

Theoretically, black pepper might increase the effects and side effects of amoxicillin.
Animal research shows that taking piperine, a constituent of black pepper, with amoxicillin increases plasma levels of amoxicillin. This has not been reported in humans.

Likelihood Possible Evidence D
Carbamazepine (Tegretol)

Theoretically, black pepper might increase blood levels of carbamazepine, potentially increasing the effects and side effects of carbamazepine.
One clinical study in patients taking carbamazepine 300 mg or 500 mg twice daily shows that taking a single 20 mg dose of purified piperine, a constituent of black pepper, increases carbamazepine levels. Piperine may increase carbamazepine absorption by increasing blood flow to the GI tract, increasing the surface area of the small intestine, or inhibiting cytochrome P450 3A4 (CYP3A4) in the gut wall. Absorption was significantly increased by 7-10 mcg/mL/hour. The time to eliminate carbamazepine was also increased by 4-8 hours. Although carbamazepine levels were increased, this did not appear to increase side effects. In vitro research also shows that piperine can increase carbamazepine levels by 11% in a time-dependent manner.

Likelihood Possible Evidence B
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, black pepper might decrease levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research suggests that black pepper induces CYP1A2. This has not been reported in humans.

Likelihood Possible Evidence D
Bioperine full monograph & interactions

Beet Root Extract3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Beet Root Extract full monograph & interactions

L-Arginine Complex9 drug types · 403 drugs

Ace Inhibitors (Aceis)

Theoretically, concomitant use of L-arginine and ACE inhibitors may increase the risk for hypotension and hyperkalemia.
Combining L-arginine with some antihypertensive drugs, especially ACE inhibitors, seems to have additive vasodilating and blood pressure-lowering effects. Furthermore, ACE inhibitors can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ACE inhibitors with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Angiotensin Receptor Blockers (Arbs)

Theoretically, concomitant use of L-arginine and ARBs may increase the risk of hypotension and hyperkalemia.
L-arginine increases nitric oxide, which causes vasodilation. Combining L-arginine with ARBs seems to increase L-arginine-induced vasodilation. Furthermore, ARBs can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients. Theoretically, concomitant use of ARBs with L-arginine may increases the risk of hyperkalemia.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of L-arginine with anticoagulant and antiplatelet drugs might have additive effects and increase the risk of bleeding.
Preliminary research suggests that L-arginine infusions reduce platelet aggregation in humans. The clinical significance of this effect is unclear.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, concomitant use of L-arginine might have additive effects with antidiabetes drugs.
Preliminary clinical research shows that L-arginine decreases blood glucose levels in patients with type 2 diabetes.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, concomitant use of L-arginine and antihypertensive drugs may increase the risk of hypotension.
L-arginine increases nitric oxide, which causes vasodilation. Clinical evidence shows that L-arginine can reduce blood pressure in some individuals with hypertension. Furthermore, combining L-arginine with some antihypertensive drugs seems to have additive vasodilating and blood pressure-lowering effects.

Likelihood Probable Evidence D
Isoproterenol (Isuprel)

Theoretically, concurrent use of isoproterenol and L-arginine might result in additive effects and hypotension.
Preliminary clinical evidence suggests that L-arginine enhances isoproterenol-induced vasodilation in patients with essential hypertension or a family history of essential hypertension.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically concomitant use of potassium-sparing diuretics with L-arginine may increases the risk of hyperkalemia.
Potassium-sparing diuretics can increase potassium levels. Use of L-arginine has been associated with hyperkalemia in some patients.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and L-arginine might increase the risk for hypotension.
In vivo, concurrent use of L-arginine and sildenafil has resulted in increased vasodilation. Theoretically, concurrent use might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
Testosterone

Theoretically, concomitant use of L-arginine and testosterone might have additive effects.
In clinical research, L-arginine increases the level of testosterone in male patients with erectile dysfunction. The clinical significance of this finding is unclear.

Likelihood Possible Evidence D
L-Arginine Complex full monograph & interactions

L-Citrulline2 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
L-Citrulline full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Magnify, from the product label.

Huge Nutrition

See all Huge Nutrition products
Name
Huge Nutrition
Street Address
Postbus 1033
City
Breda
ZipCode
4811BH
Phone Number
31 65 059 0211
Web Address
www.hugesupplements.com
Pharmacist Counseling Corner

Magnify by Huge Nutrition: Common Questions

Does Magnify by Huge Nutrition interact with any medications?
Yes. Based on its ingredients, Magnify has a known interaction with 1,156 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Magnify contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does L-arginine actually do?
L-arginine is an amino acid your body uses to make nitric oxide, a molecule that relaxes blood vessels and improves blood flow. This is why it can lower blood pressure and is studied for athletic performance and circulation.
Can I take this if I'm on blood pressure medication?
Not without checking first. L-arginine, L-citrulline, and beet root extract can all lower blood pressure, and combining them with your medication could drop it too far. Talk to your doctor or pharmacist before starting—they may need to adjust your dose or monitor you closely.
What's Bioperine, and why is it in here?
Bioperine is a black pepper extract that helps your body absorb other ingredients better. The downside: it can also slow how your liver clears certain medications, which means those drugs can build up to higher levels in your blood. This is a big reason to check your medications before taking this product.
Will this give me side effects?
The most common ones are mild: abdominal pain, bloating, nausea, diarrhea, headache, and flushing. L-citrulline may cause heartburn or stomach discomfort. Beet root extract can turn your stools red or black, which is harmless but startling. Most people tolerate it well short-term.
Is this safe during pregnancy or breastfeeding?
L-arginine is possibly safe in pregnancy, but L-citrulline and beet data aren't on file—talk with your doctor. For breastfeeding, L-citrulline should be avoided; Bioperine is likely safe; and L-arginine and beet data aren't established. Your doctor or pharmacist can give you personalized advice.
Does this actually work for muscle or athletic performance?
L-citrulline and beet root extract are both possibly effective for athletic performance based on the data we hold. Evidence is limited but shows promise. The other ingredients don't have effectiveness ratings in our data.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Magnify label
Go deeper

The Full Monographs Behind Magnify’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

L-citrulline

Interacts with 178 drugs

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...

Read the full L-citrulline monograph → Herb & supplement monograph

Black Pepper

Interacts with 1,019 drugs

Black pepper is a common kitchen spice that is generally safe in the amounts used in food. Its extract, piperine, is mostly added to supplements to help the body absorb other ingredients (li...

Read the full Black Pepper monograph → Herb & supplement monograph

Beet

Interacts with 861 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph → Herb & supplement monograph

L-arginine

Interacts with 403 drugs

L-arginine is an amino acid that the body uses to make nitric oxide, a substance that helps blood vessels relax and widen. It is popularly used for blood pressure, erectile dysfunction, and...

Read the full L-arginine monograph →
Sources

Sources & How We Checked

Magnify's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 117 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

L-arginine 66 references
  1. Sapienza MA, Kharitonov SA, Horvath I, et al. Effect of inhaled L-arginine on exhaled nitric oxide in normal and asthmatic subjects. Thorax 1998;53:172-5.
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Beet 14 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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