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Dietary supplement

Magnolia Bark Extract 30 mg Ingredients & Drug Interactions

by tnvitamins

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Magnolia Bark Extract 30 mg is a dietary supplement by tnvitamins with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, digestive upset.Based on those ingredients, 351 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Magnolia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Magnolia Bark Extract 30 mg by tnvitamins

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: magnolia bark extract at 30 mg per capsule. Magnolia bark comes from a tree used in traditional medicine for centuries; its main active compounds are honokiol and magnolol.

The capsule also holds inactive ingredients — cellulose, magnesium stearate, rice flour, and silica — which help form and stabilize the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Magnolia's overall clinical evidence instead.

Moderate

Some clinical evidence supports Magnolia for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Gingivitis — rated "Possibly Effective" (Natural Medicines).

The evidence for magnolia is mixed. For gingivitis (gum inflammation), it's rated possibly effective, meaning some research supports it but more data would help confirm the benefit.

For allergic rhinitis (hay fever) and anxiety, the evidence isn't established yet — we don't have enough reliable data to say whether it works. Dental plaque prevention also lacks sufficient evidence in our data.

The evidence, ingredient by ingredient Magnolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Taken by mouth, magnolia bark is generally well tolerated in short term, though long-term human safety data is limited. The main caution is pregnancy — magnolia is rated unsafe during pregnancy because of concerns it may affect the uterus, so you should avoid it if you're pregnant or trying to become pregnant.

There isn't enough safety data during breastfeeding either, so it's best avoided then too. In clinical trials, a small number of participants reported side effects like sexual dysfunction, shaking hands, numbness around the mouth, fatigue, and headache, though it's unclear whether magnolia was responsible.

Side effects, ingredient by ingredient Magnolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Magnolia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 351 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take magnolia bark extract, check with your doctor or pharmacist if you're on any CNS depressants (sedatives, sleep aids, anxiety medications) or blood thinners and antiplatelet drugs (like warfarin or aspirin). Both interactions are rated Moderate, meaning the combination could meaningfully change how your drugs work or raise your risk of side effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Magnolia bark extract might interest you if you're looking into natural options for gum health, but the evidence for other uses isn't solid yet. If you take blood thinners, antiplatelet drugs, or sedating medications, talk with your doctor or pharmacist before starting — the interaction risk is real.

Pregnant or breastfeeding people should avoid it. Use the medication checker on this page to confirm your prescriptions are clear first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Magnolia Bark Extract 30 mg, straight from the product label.

Brand tnvitamins
Barcode (UPC) 095234274501
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 217832
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Magnolia Bark Extract 30 mg by tnvitamins, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
095234274501
IngredientAmount% DV
Magnolia30 mg--

Other ingredients: Cellulose, Magnesium Stearate, Rice Flour, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Standardized Magnolia bark extrct Active honokiol

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one (1) veggie capsule per day with water, or as directed by a health care professional.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur. Consult your healthcare provider before using this product if you have a medical condition, especially depression, schizophrenia or epilepsy.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Storage

Store in a cool, dry place.

General Statements

Reorder tnvitamins.com 800-645-4446

See for yourself

Magnolia Bark Extract 30 mg by tnvitamins label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Magnolia Bark Extract 30 mg by tnvitamins

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Magnolia

Interacts with
351 drugs
30 mg per serving Form: Honokiol

Magnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion. Modern human r...

Magnolia monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate, Rice Flour, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Magnolia Bark Extract 30 mg by tnvitamins Drug Interactions

Want to check YOUR meds against Magnolia Bark Extract 30 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
351Drugs
351 Moderate

Ingredients driving the most interactions

Magnolia 351

Each ingredient & the kinds of drugs it affects

For each ingredient in Magnolia Bark Extract 30 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Magnolia2 drug types · 351 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro research shows that the chemicals magnolol and honokiol, isolated from magnolia bark, inhibit platelet aggregation that is experimentally induced by collagen and arachidonic acid. However, they do not inhibit platelet aggregation that is induced by adenosine diphosphate, platelet-activating factor, or thrombin. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
In vitro and animal research shows that constituents extracted from magnolia bark, especially honokiol and magnolol, have sedative effects. These effects may be due to the inhibition of catecholamine release and modulation of gamma-aminobutyric acid-A (GABA-A) receptors.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Magnolia Bark Extract 30 mg, from the product label.

tnvitamins

See all tnvitamins products
Name
TOTAL NUTRITION, INC.
City
FARMINGDALE
State
NY
ZipCode
11735
Phone Number
800-645-4446
Web Address
tnvitamins.com
Pharmacist Counseling Corner

Magnolia Bark Extract 30 mg by tnvitamins: Common Questions

Does Magnolia Bark Extract 30 mg by tnvitamins interact with any medications?
Yes. Based on its ingredients, Magnolia Bark Extract 30 mg has a known interaction with 351 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Magnolia Bark Extract 30 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No — magnolia is rated unsafe during pregnancy because it may affect the uterus, so you should avoid it if you're pregnant or trying to conceive. There's also not enough safety data during breastfeeding, so it's best avoided then too. Talk with your doctor or pharmacist about safer options.
Will magnolia help my anxiety?
We don't have enough reliable evidence to say whether it works for anxiety. The lab research is promising — magnolia compounds do have sedative effects — but human clinical trials haven't established it yet.
Is it used for gum health?
Yes, magnolia is rated possibly effective for gingivitis (gum inflammation), meaning some research supports it. For dental plaque, though, we don't have enough evidence to know if it helps.
What side effects might I get?
Taken by mouth, magnolia is generally well tolerated. In clinical trials, a small number of people reported sexual dysfunction, hand shaking, numbness around the mouth, fatigue, and headache — though it's not clear if magnolia caused them. Long-term safety data in humans is limited.
Is this safe to take long-term?
Short-term use appears okay for many adults, but human safety data over longer periods is limited. Talk with your pharmacist or doctor about how long you plan to take it and whether that's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Magnolia Bark Extract 30 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Magnolia Bark Extract 30 mg label
Go deeper

The Full Monographs Behind Magnolia Bark Extract 30 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Magnolia Bark Extract 30 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Magnolia 9 references
  1. Kuribara H, Kishi E, Hattori N, et al. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol 2000;52:1425-9. PubMed
  2. Tachikawa E, Takahashi M, Kashimoto T. Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells. Biochem Pharmacol 2000;60:433-40. PubMed
  3. Jung KY, Kim DS, Oh SR, et al. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii. J Nat Prod 1998;61:808-11.
  4. Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4.
  5. Teng CM, Chen CC, Ko FN, et al. Two antiplatelet agents from Magnolia officinalis. Thromb Res 1988;50:757-65. PubMed
  6. Ghys K, De Palma A, Vandevenne A, Werbrouck J, Goossens A. Magnolia officinalis bark extract, a recently identified contact allergen in 'anti-ageing' cosmetics. Contact Dermatitis. 2015 Aug;73(2):130-2.
  7. Raison-Peyron N, Césaire A, Du-Thanh A, Dereure O. Allergic contact dermatitis caused by Magnolia officinalis bark extract in a facial anti-ageing cream. Contact Dermatitis. 2015 Jun;72(6):416-7.
  8. Nilausen TD, Johansen JD, Thyssen JP. Allergic contact dermatitis of the face caused by Magnolia officinalis bark extract. Contact Dermatitis. 2016;75(6):385-87.
  9. Amat-Samaranch V, López-Sánchez C, Tubau C, Puig L, Serra-Baldrich E. Vulvar allergic contact dermatitis caused by Magnolia officinalis bark extract. Contact Dermatitis 2022;87(1):96-97.

See these in context on the Magnolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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