Pinellia & Magnolia Teapills Ingredients & Drug Interactions
by Plum Flower
What is this page for?
First and foremost: checking Pinellia & Magnolia Teapills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Pinellia & Magnolia Teapills is a dietary supplement by Plum Flower with 5 active ingredients. Its ingredients are commonly taken for anxiety and stress, sleep problems, digestive upset.Based on those ingredients, 1,210 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Zingiber officinale Rhizome Extract, Poria cocos Sclerotium Extract, Magnolia officinalis Bark Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Pinellia & Magnolia Teapills by Plum Flower
Ask about any prescription or over-the-counter medication and we check it for interactions with Pinellia & Magnolia Teapills by Plum Flower — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Pinellia & Magnolia Teapills by Plum Flower
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains five active herbal extracts in a proprietary blend: Magnolia officinalis bark, Poria cocos mushroom, Pinellia ternata rhizome, ginger (Zingiber officinale), and Perilla frutescens leaf. The inactive ingredients are maltose, microcrystalline cellulose, magnesium silicate, activated charcoal, and china wax — standard tablet binders and fillers.
Does it work?
Moderate evidence
The evidence for what this product does is mixed and largely incomplete. Ginger has possibly effective evidence for pregnancy-related nausea, period pain, and osteoarthritis.
Magnolia bark has possibly effective evidence for gingivitis (gum disease), but the other conditions studied — allergic rhinitis, anxiety, and dental plaque — lack reliable evidence. For the other three ingredients, the effectiveness research we hold either shows insufficient evidence or hasn't been established in our data.
How safe is it?
Well-documented data
Magnolia bark is generally well tolerated orally, though human safety data are limited. The safety notes advise against use in pregnancy and breastfeeding because there isn't enough information.
Poria mushroom is well tolerated in traditional use, but pregnancy and breastfeeding data are inadequate — avoidance is recommended. Pinellia ternata carries a caution: raw material is toxic and irritating, so only properly processed preparations should be used.
It also contains ephedrine alkaloids, which may cause high blood pressure, rapid heartbeat, heart attack, stroke, or seizures. Avoid in pregnancy and breastfeeding.
Ginger is generally well tolerated at typical food and supplement doses, though higher doses (over 5 grams per day) increase side effects like heartburn, diarrhea, and stomach upset. Perilla is well tolerated as a food, but rare anaphylaxis has been reported with perilla seeds.
Pregnancy and breastfeeding data are insufficient.
Meds to double-check
Moderate interaction found
Check before taking this if you use benzodiazepines or other sedatives (Pinellia may make them stronger), blood thinners like warfarin (Magnolia and ginger may raise bleeding risk), diabetes medications (ginger may lower blood sugar more), blood pressure drugs like losartan or nifedipine (ginger may enhance effects), anticholinergic or cholinergic drugs (Poria may interfere), or certain cancer medications (ginger may alter how your body processes them). All of these interactions are rated Moderate.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a traditional herbal blend used for respiratory and digestive support, but the evidence for what it actually does is sparse. If you take sedatives, blood thinners, diabetes drugs, or blood pressure medication, you need to check with your pharmacist before starting it — the interactions are real enough to matter.
If you're pregnant or nursing, talk with your doctor first; safety data are too thin to move ahead on your own.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Pinellia & Magnolia Teapills, straight from the product label.
| Brand | Plum Flower |
|---|---|
| Barcode (UPC) | 739934833353 |
| Net contents | 200 Pill(s); 1.2 Ounce(s); 34 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2024 |
| DSLD ID | 310582 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Pinellia & Magnolia Teapills by Plum Flower, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 1360 mg | -- |
| Magnolia officinalis Bark Extract | 0 NP | -- |
| Poria cocos Sclerotium Extract | 0 NP | -- |
| Pinellia ternata Rhizome Extract | 0 NP | -- |
| Zingiber officinale Rhizome Extract | 0 NP | -- |
| Perilla frutescens leaf extract | 0 NP | -- |
Other ingredients: Maltose, Microcrystalline Cellulose, Magnesium Silicate, Carbon, Activated, China Wax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Ban Xia Hou Po Wan
FDA Statement of Identity
Herbal Supplement
Suggested/Recommended/Usage/Directions
Take 8 pills 3 times daily or as directed by your health care practitioner.
Precautions
Caution during pregnancy
Keep out of reach of children
Seals/Symbols
Plum Flower Guarantee Sourced sustainably FDA Registered cGMP Compliant Made at a cGMP Facility Lab Tested Quality Verified Species Verified
General Statements
Foci Pharmaceuticals 1929
Formulation
US owned and operated since 1969. Made in China in partnership with the award-winning Lanzhou Foci Pharmaceutical Co. Ltd.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Pinellia & Magnolia Teapills by Plum Flower label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Pinellia & Magnolia Teapills by Plum Flower
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size8 Pill(s) Dosage formTablet Or Pill Servings per container25 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Maltose, Microcrystalline Cellulose, Magnesium Silicate, Carbon, Activated, China Wax. These complete the product’s ingredient list but are not active constituents.
Pinellia & Magnolia Teapills by Plum Flower Drug Interactions
HelloPharmacist Interaction Report
Pinellia & Magnolia Teapills by Plum Flower contains five active ingredients, three of which have documented interactions with medications.
The most serious concern is Pinellia ternata, which may amplify the effects of sedative drugs (benzodiazepines, barbiturates, and other CNS depressants) — potentially causing excessive drowsiness or dangerous drops in alertness. Animal research shows Pinellia increases sleeping time, and this effect could add to what your medication is already doing.
Read the full breakdown — every affected drug type, severity by severity
Magnolia bark and ginger also interact with blood thinners (anticoagulants and antiplatelet drugs like warfarin). Magnolia may increase bleeding risk through effects on platelet clotting, while ginger has shown mixed but concerning results in case reports and lab work.
Ginger additionally interacts with diabetes medications (which could lower blood sugar further), blood pressure drugs like losartan and nifedipine, and certain cancer medications metabolized by your liver.
Poria mushroom extract theoretically affects drugs that work on the nervous system and muscles — specifically anticholinergic and cholinergic medications — though this hasn't been shown in humans. Altogether, these interactions span 1,195 individual medications.
Perilla leaf extract was not checked in our data — we hold no interaction information for it.
Check your exact medications using the tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Pinellia & Magnolia Teapills?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Pinellia & Magnolia Teapills interact with 1,210 drugs. Click any drug to see the details.
4 of the 5 ingredients in Pinellia & Magnolia Teapills interact with drugs. Each result below shows which ingredient is responsible. Zingiber officinale Rhizome Extract Poria cocos Sclerotium Extract Magnolia officinalis Bark Extract Pinellia ternata Rhizome Extract
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Pinellia & Magnolia Teapills — through 1 ingredient. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Zingiber Officinale Rhizome Extract + Abciximab interactionMagnolia Officinalis Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Officinalis Bark Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Pinellia & Magnolia Teapills — through 1 ingredient. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Pinellia & Magnolia Teapills — through 1 ingredient. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Pinellia & Magnolia Teapills — through 1 ingredient. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Magnolia Officinalis Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Officinalis Bark Extract + Abrocitinib interactionZingiber Officinale Rhizome ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Zingiber Officinale Rhizome Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Pinellia & Magnolia Teapills — through 1 ingredient. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Pinellia & Magnolia Teapills — through 1 ingredient. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Zingiber Officinale Rhizome Extract + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Zingiber Officinale Rhizome Extract + Acenocoumarol interactionMagnolia Officinalis Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Officinalis Bark Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Pinellia & Magnolia Teapills — through 3 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractCns Depressants, Anticholinergic Drugs Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acepromazine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acepromazine interactionPinellia Ternata Rhizome ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata Rhizome Extract + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Aspirin interactionMagnolia Officinalis Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Aspirin, Caffeine interactionMagnolia Officinalis Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Pinellia Ternata Rhizome ExtractBarbiturates Moderate
Interaction Summary
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata Rhizome Extract + Acetaminophen, Butalbital interactionZingiber Officinale Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Pinellia Ternata Rhizome ExtractBarbiturates Moderate
Interaction Summary
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata Rhizome Extract + Acetaminophen, Butalbital, Caffeine interactionZingiber Officinale Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Pinellia & Magnolia Teapills — through 4 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionPinellia Ternata Rhizome ExtractBarbiturates, Cns Depressants Moderate
Interaction Summary
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata Rhizome Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Pinellia & Magnolia Teapills — through 4 ingredients. Tap an ingredient for the detail:
Pinellia Ternata Rhizome ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata Rhizome Extract + Acetaminophen, Butalbital, Codeine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Butalbital, Codeine interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Butalbital, Codeine interactionZingiber Officinale Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Pinellia & Magnolia Teapills — through 4 ingredients. Tap an ingredient for the detail:
Magnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionPinellia Ternata Rhizome ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata Rhizome Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionZingiber Officinale Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Pinellia & Magnolia Teapills — through 4 ingredients. Tap an ingredient for the detail:
Magnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionZingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPinellia Ternata Rhizome ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata Rhizome Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Pinellia & Magnolia Teapills — through 4 ingredients. Tap an ingredient for the detail:
Pinellia Ternata Rhizome ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata Rhizome Extract + Acetaminophen, Caffeine, Codeine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Caffeine, Codeine interactionZingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Caffeine, Codeine interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Pinellia & Magnolia Teapills — through 4 ingredients. Tap an ingredient for the detail:
Magnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionZingiber Officinale Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPinellia Ternata Rhizome ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata Rhizome Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Pinellia & Magnolia Teapills — through 4 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionPinellia Ternata Rhizome ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata Rhizome Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Pinellia & Magnolia Teapills — through 1 ingredient. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Caffeine, Pyrilamine interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Pinellia & Magnolia Teapills — through 4 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractAnticholinergic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionZingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionPinellia Ternata Rhizome ExtractCns Depressants Moderate
Interaction Summary
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time.
Read the full Pinellia Ternata Rhizome Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionZingiber Officinale Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Pinellia & Magnolia Teapills — through 2 ingredients. Tap an ingredient for the detail:
Zingiber Officinale Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Zingiber Officinale Rhizome Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Pinellia & Magnolia Teapills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Zingiber officinale Rhizome Extract
Anticoagulant/Antiplatelet Drugs
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, research is conflicting.
Laboratory research suggests that ginger inhibits thromboxane synthetase and decreases platelet aggregation. However, this has not been demonstrated unequivocally in humans, with mixed results from clinical trials. Theoretically, excessive amounts of ginger might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Antidiabetes Drugs
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Animal and human research suggests that ginger might increase insulin levels and/or decrease blood glucose levels.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Ginger might increase or decrease the levels of CYP3A4 substrates.
In vitro research and some case reports suggest that ginger inhibits CYP3A4 activity. Three case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are CYP3A4 substrates (imatinib, dabrafenib, and crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Conversely, other in vitro research suggests that ginger induces CYP3A4 activity, leading to reduced levels of CYP3A4 substrates. However, this interaction has not been reported in humans.
Losartan (Cozaar)
Theoretically, ginger might increase levels of losartan and the risk of hypotension.
In animal research, ginger increased the levels and hypotensive effects of a single dose of losartan. It is not clear if ginger alters the concentration or effects of losartan when taken continuously. Additionally, this interaction has not been shown in humans.
Nifedipine (Procardia)
Ginger may have antiplatelet effects and increase the risk of bleeding if used with nifedipine.
Clinical research shows that combined treatment with ginger 1 gram plus nifedipine 10 mg significantly inhibits platelet aggregation when compared to nifedipine or ginger alone.
P-Glycoprotein Substrates
Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
In vitro research and case reports suggest that ginger inhibits drug efflux by P-gp, potentially increasing absorption and serum levels of P-gp substrates. Two case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are P-gp substrates (trametinib, crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Phenprocoumon (Marcoumar, Others)
Ginger might increase the risk of bleeding with phenprocoumon.
Phenprocoumon, a warfarin-related anticoagulant, might increase the international normalized ratio (INR) when taken with ginger. There is one case report of a 76-year-old woman with a stable INR on phenprocoumon that increased to greater than 10 when she began consuming dried ginger and ginger tea.
Warfarin (Coumadin)
Ginger might increase the risk of bleeding with warfarin.
Laboratory research suggests that ginger might inhibit thromboxane synthetase and decrease platelet aggregation. In one case report, ginger increased the INR when taken with phenprocoumon, which has similar pharmacological effects as warfarin. In another case report, ginger increased the INR when taken with a combination of warfarin, hydrochlorothiazide, and acetaminophen. A longitudinal analysis suggests that taking ginger increases the risk of bleeding in patients taking warfarin for at least 4 months. However, research in healthy people suggests that ginger has no effect on INR, or the pharmacokinetics or pharmacodynamics of warfarin. Until more is known, monitor INRs closely in patients taking large amounts of ginger.
Calcium Channel Blockers
Theoretically, taking ginger with calcium channel blockers might increase the risk of hypotension.
Some animal and in vitro research suggests that ginger has hypotensive and calcium channel-blocking effects. Another animal study shows that concomitant administration of ginger and the calcium channel blocker amlodipine leads to greater reductions in blood pressure when compared with amlodipine alone.
Cyclosporine (Neoral, Sandimmune)
Theoretically, when taken prior to cyclosporine, ginger might decrease cyclosporine levels.
In an animal model, ginger juice taken 2 hours prior to cyclosporine administration reduced the maximum concentration and area under the curve of cyclosporine by 51% and 40%, respectively. This effect was not observed when ginger juice and cyclosporine were administered at the same time.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, ginger might increase the levels of CYP1A2 substrates.
In vitro research shows that ginger inhibits CYP1A2 activity. However, this interaction has not been reported in humans.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, ginger might increase the levels of CYP2B6 substrates.
In vitro research shows that ginger inhibits CYP2B6 activity. However, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, ginger might increase the levels of CYP2C9 substrates.
In vitro research shows that ginger inhibits CYP2C9 activity. However, this interaction has not been reported in humans.
Metronidazole (Flagyl)
Theoretically, ginger might increase levels of metronidazole.
In an animal model, ginger increased the absorption and plasma half-life of metronidazole. In addition, the elimination rate and clearance of metronidazole was significantly reduced.
Poria cocos Sclerotium Extract
Anticholinergic Drugs
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cholinergic Drugs
Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cns Depressants
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.
Magnolia officinalis Bark Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro research shows that the chemicals magnolol and honokiol, isolated from magnolia bark, inhibit platelet aggregation that is experimentally induced by collagen and arachidonic acid. However, they do not inhibit platelet aggregation that is induced by adenosine diphosphate, platelet-activating factor, or thrombin. This interaction has not been reported in humans.
Cns Depressants
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
In vitro and animal research shows that constituents extracted from magnolia bark, especially honokiol and magnolol, have sedative effects. These effects may be due to the inhibition of catecholamine release and modulation of gamma-aminobutyric acid-A (GABA-A) receptors.
Pinellia ternata Rhizome Extract
Barbiturates
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time. Theoretically, Pinellia ternata can potentiate the therapeutic effect of barbiturates. Some of these sedative medications include pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), and others.
Benzodiazepines
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time. Theoretically, Pinellia ternata can potentiate the therapeutic effect of benzodiazepines. Some benzodiazepines include lorazepam (Ativan), alprazolam (Xanax), diazepam (Valium), midazolam (Versed), and others.
Cns Depressants
Evidence from animal research shows that a Pinellia ternata preparation decreases activity and increases sleeping time. Theoretically, Pinellia ternata can potentiate the therapeutic effect of CNS depressants. Some of these medications include antihistamines, barbiturates, benzodiazepines, tricyclic antidepressants, and others.
Brand information
Manufacturer and brand details for Pinellia & Magnolia Teapills, from the product label.
Plum Flower
- Name
- Mayway Herbs
- City
- Oakland
- State
- CA
- Web Address
- www.plumflowerherbs.com
Pinellia & Magnolia Teapills by Plum Flower: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Pinellia & Magnolia Teapills’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Magnolia
Interacts with 351 drugsMagnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion. Modern human research is still limited, so we can't be...
Read the full Magnolia monograph → Herb & supplement monographPoria Mushroom
Interacts with 417 drugsPoria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...
Read the full Poria Mushroom monograph → Herb & supplement monographPinellia Ternata
Interacts with 256 drugsPinellia ternata is a tuber used in traditional Chinese medicine, most often for nausea, vomiting, and phlegmy coughs, and almost always as part of multi-herb formulas. The raw plant is toxi...
Read the full Pinellia Ternata monograph → Herb & supplement monographGinger
Interacts with 1,007 drugsGinger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nausea and vomiting, including from motion sickness, pr...
Read the full Ginger monograph → Herb & supplement monographPerilla
Perilla is an Asian mint-family plant used in cooking and traditional medicine, mainly for allergy, breathing, and digestive complaints. Most human evidence is limited or preliminary, so it...
Read the full Perilla monograph →Sources & How We Checked
Pinellia & Magnolia Teapills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 84 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Magnolia 9 references
- Kuribara H, Kishi E, Hattori N, et al. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol 2000;52:1425-9. PubMed
- Tachikawa E, Takahashi M, Kashimoto T. Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells. Biochem Pharmacol 2000;60:433-40. PubMed
- Jung KY, Kim DS, Oh SR, et al. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii. J Nat Prod 1998;61:808-11.
- Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4.
- Teng CM, Chen CC, Ko FN, et al. Two antiplatelet agents from Magnolia officinalis. Thromb Res 1988;50:757-65. PubMed
- Ghys K, De Palma A, Vandevenne A, Werbrouck J, Goossens A. Magnolia officinalis bark extract, a recently identified contact allergen in 'anti-ageing' cosmetics. Contact Dermatitis. 2015 Aug;73(2):130-2.
- Raison-Peyron N, Césaire A, Du-Thanh A, Dereure O. Allergic contact dermatitis caused by Magnolia officinalis bark extract in a facial anti-ageing cream. Contact Dermatitis. 2015 Jun;72(6):416-7.
- Nilausen TD, Johansen JD, Thyssen JP. Allergic contact dermatitis of the face caused by Magnolia officinalis bark extract. Contact Dermatitis. 2016;75(6):385-87.
- Amat-Samaranch V, López-Sánchez C, Tubau C, Puig L, Serra-Baldrich E. Vulvar allergic contact dermatitis caused by Magnolia officinalis bark extract. Contact Dermatitis 2022;87(1):96-97.
Poria Mushroom 3 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
- Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.
Pinellia Ternata 4 references
- Kim SH, Jeong H, Kim YK, et al. IgE-mediated occupational asthma induced by herbal medicine, Bahna (Pinellia ternata). Clin Exp Allergy 2000;31:779-81.
- FDA, HHS. Final rule declaring dietary supplements containing ephedrine alkaloids adulterated because they present an unreasonable risk. Fed Regist 2004;69:6787-6854.
- Lin S, Nie B, Yao G, Yang H, Ye R, Yuan Z. Pinellia ternata (Thunb.) makino preparation promotes sleep by increasing REM sleep. Nat Prod Res. 2019;33(22):3326-3329. PubMed
- Lin YH, Chen C, Zhao X, et al. Efficacy and Safety of Banxia Formulae for Insomnia: A Systematic Review and Meta-Analysis of High-Quality Randomized Controlled Trials. Evid Based Complement Alternat Med 2021;2021:8833168. PubMed
Ginger 64 references
- Fischer-Rasmussen W, Kjaer SK, Dahl C, Asping U. Ginger treatment of hyperemesis gravidarum. Eur J Obstet Gynecol Reprod Biol 1991;38:19-24. PubMed
- Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev 2000;(2):CD000145. PubMed
- Vutyavanich T, Kraisarin T, Ruangsri R. Ginger for nausea and vomiting in pregnancy: randomized, double-masked, placebo-controlled trial. Obstet Gynecol 2001;97:577-82. DOI
- Backon J. Ginger in preventing nausea and vomiting of pregnancy; a caveat due to its thromboxane synthetase activity and effect on testosterone binding. Eur J Obstet Gynecol Reprod Biol 1991;42:163-4. PubMed
- Srivastava KC. Effect of onion and ginger consumption on platelet thromboxane production in humans. Prostaglandins Leukot Essent Fatty Acids 1989;35:183-5. PubMed
- Stewart JJ, Wood MJ, Wood CD, Mims ME. Effects of ginger on motion sickness susceptibility and gastric function. Pharmacology 1991;42:111-20. PubMed
- Smith C, Crowther C, Willson K, et al. A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstet Gynecol 2004;103:639-45. PubMed
- Portnoi G, Chng LA, Karimi-Tabesh L, et al. Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancy. Am J Obstet Gynecol 2003;189:1374-7.. PubMed
- Wigler I, Grotto I, Caspi D, Yaron M. The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis. Osteoarthritis Cartilage 2003;11:783-9. PubMed
- Ghayur MN, Gilani AH. Ginger lowers blood pressure through blockade of voltage-dependent calcium channels. J Cardiovasc Pharmacol 2005;45:74-80. PubMed
- Thomson M, Al-Qattan KK, Al-Sawan SM, et al. The use of ginger (Zingiber officinale Rosc.) as a potential anti-inflammatory and antithrombotic agent. Prostaglandins Leukot Essent Fatty Acids 2002;67:475-8. PubMed
- Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices. Contact Dermatitis 1996;35:157-62. PubMed
- Akhani SP, Vishwakarma SL, Goyal RK. Anti-diabetic activity of Zingiber officinale in streptozotocin-induced type I diabetic rats. J Pharm Pharmacol 2004;56:101-5.
- Kruth P, Brosi E, Fux R, et al. Ginger-associated overanticoagulation by phenprocoumon. Ann Pharmacother 2004;38:257-60. PubMed
- Jiang X, Williams KM, Liauw WS, et al. Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. Br J Clin Pharmacol 2005;59:425-32. PubMed
- Borrelli F, Capasso R, Aviello G, et al. Effectiveness and safety of ginger in the treatment of pregnancy-induced nausea and vomiting. Obstet Gynecol 2005;105:849-56. PubMed
- Smith C, Crowther C, Wilson K et al. A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstet Gynecol 2004;103:639-45. PubMed
- Jiang X, Blair EY, McLachlan AJ. Investigation of the effects of herbal medicines on warfarin response in healthy subjects: a population pharmacokinetic-pharmacodynamic modeling approach. J Clin Pharmacol 2006;46:1370-8. PubMed
- Chittumma P, Kaewkiattikun K, Wiriyasiriwach B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 2007;90:15-20.
- Ozgoli G, Goli M, Moattar F. Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. J Altern Complement Med 2009;15:129-32. PubMed
- Black CD, Herring MP, Hurley DJ, O'Connor PJ. Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. J Pain 2010;11:894-903. PubMed
- Heitmann K, Nordeng H, Holst L. Safety of ginger use in pregnancy: results from a large population-based cohort study. Eur J Clin Pharmacol 2012 Jun 17. PubMed
- Ryan JL, Heckler CE, Roscoe JA, et al. Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients. Support Care Cancer. 2012;20:1479-89. PubMed
- Backon J. Ginger as an antiemetic: possible side effects due to its thromboxane synthetase activity. Anaesthesia. 1991;46(8):705-6.. PubMed
- Abebe W. Herbal medication: potential for adverse interactions with analgesic drugs. J Clin Pharm Ther. 2002;27:391-401. PubMed
- Argento A, Tiraferri E, Marzaloni M. [Oral anticoagulants and medicinal plants. An emerging interaction]. Ann Ital Med Int. 2000;15:139-43.
- Young HY, Liao JC, Chang YS, et al. Synergistic effect of ginger and nifedipine on human platelet aggregation: a study in hypertensive patients and normal volunteers. Am J Chin Med. 2006;34:545-51. PubMed
- Greenway FL, Liu Z, Martin CK, et al. Safety and efficacy of NT, an herbal supplement, in treating human obesity. Int J Obes (Lond). 2006;30:1737-41. PubMed
- Shalansky S, Lynd L, Richardson K, et al. Risk of warfarin-related bleeding events and supratherapeutic international normalized ratios associated with complementary and alternative medicine: a longitudinal analysis. Pharmacotherapy. 2007;27:1237-47. PubMed
- Lesho EP, Saullo L, Udvari-Nagy S. A 76-year-old woman with erratic anticoagulation. Cleve Clin J Med. 2004;71:651-6. PubMed
- Okonta JM, Uboh M, Obonga WO. Herb-Drug Interaction: A Case Study of Effect of Ginger on the Pharmacokinetic of Metronidazole in Rabbit. Indian Journal of Pharmaceutical Sciences (India) 2008;70(230):232. PubMed
- Chiang HM, Chao PD, Hsiu SL, et al. Ginger significantly decreased the oral bioavailability of cyclosporine in rats. Am J Chin Med. 2006;34:845-55. PubMed
- Bhandari U, Kanojia R, Pillai KK. Effect of ethanolic extract of Zingiber officinale on dyslipidaemia in diabetic rats. J Ethnopharmacol. 2005;97:227-30. PubMed
- Ojewole JA. Analgesic, antiinflammatory and hypoglycaemic effects of ethanol extract of Zingiber officinale (Roscoe) rhizomes (Zingiberaceae) in mice and rats. Phytother Res. 2006;20:764-72.
- Al-Amin ZM, Thomson M, Al-Qattan KK, et al. Anti-diabetic and hypolipidaemic properties of ginger (Zingiber officinale) in streptozotocin-induced diabetic rats. Br J Nutr. 2006;96:660-6.
- Islam MS, Choi H. Comparative effects of dietary ginger (Zingiber officinale) and garlic (Allium sativum) investigated in a type 2 diabetes model of rats. J Med Food. 2008;11:152-9.
- Cady RK, Goldstein J, Nett R, et al. A double-blind placebo-controlled pilot study of sublingual feverfew and ginger (LipiGesic M) in the treatment of migraine. Headache 2011;51:1078-86.
- Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
- Sripramote, M. and Lekhyananda, N. A randomized comparison of ginger and vitamin B6 in the treatment of nausea and vomiting of pregnancy. J Med Assoc.Thai. 2003;86(9):846-853.
- Lohsiriwat, S., Rukkiat, M., Chaikomin, R., and Leelakusolvong, S. Effect of ginger on lower esophageal sphincter pressure. J.Med.Assoc.Thai. 2010;93(3):366-372.
- Liu, P. H. and Ho, H. L. Ginger and drug bezoar induced small bowel obstruction. J R.Coll.Surg.Edinb. 1983;28(6):397-398.
- Maghbooli M, Golipour F, Moghimi Esfandabadi A, Yousefi M. Comparison between the efficacy of ginger and sumatriptan in the ablative treatment of the common migraine. Phytother Res 2014;28(3):412-5. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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