Male Fern Ingredients & Drug Interactions
by Pure Herbs
What is this page for?
First and foremost: checking Male Fern against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Male Fern is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for intestinal worms (especially tapeworm), traditional deworming remedy, folk wound care.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Male Fern by Pure Herbs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Pure Herbs Male Fern Liquid contains one active ingredient: male fern root extract. There are no inactive ingredients listed.
Does it work?
Couldn't assess
The effectiveness of male fern for hemorrhoids, intestinal parasite infection, rheumatoid arthritis, and wound healing all falls into insufficient reliable evidence — meaning the research isn't strong enough to tell whether it actually works for these uses. Before taking this product, talk with your doctor about whether there's a more established treatment option for what you're dealing with.
How safe is it?
Well-documented data
Male fern is potentially toxic with a very narrow safety margin — the difference between a dose intended to be therapeutic and a poisonous dose is small and unpredictable. Common side effects from oral use include nausea, diarrhea, headaches, tremors, and vertigo.
Rare but serious adverse effects include muscle weakness, seizures, optic neuritis (nerve damage in the eye), temporary or permanent blindness, cardiac and respiratory failure, coma, and death in cases of severe poisoning. Male fern is considered unsafe in pregnancy due to toxicity and the risk of harm to the pregnancy.
Safety during breastfeeding is unknown, but the toxicity risk means it should be avoided. Because of the narrow safety margin and serious potential harms, talk with your doctor or pharmacist before taking this product.
Meds to double-check
No known interactions
No interactions are documented for male fern with any medications in our data. However, the serious safety and toxicity concerns with this product itself — independent of drug interactions — mean you should talk with your doctor or pharmacist before starting it.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
Male fern has insufficient evidence to support its use for hemorrhoids, parasite infection, arthritis, or wound healing. More importantly, it's potentially toxic with a dangerously narrow margin between an intended dose and a poisonous one — side effects can range from mild (nausea, headaches) to life-threatening (seizures, blindness, cardiac failure).
It's unsafe in pregnancy and during breastfeeding. Before taking this product, discuss it with your doctor or pharmacist to understand the real risks and whether a safer alternative exists for your needs.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Male Fern, straight from the product label.
| Brand | Pure Herbs |
|---|---|
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Dec 13, 2022 |
| DSLD ID | 278808 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Male Fern by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.
Shake well before use
Formulation
Beneficial as a tonic for overall health. Helps to support the body's natural ability to remove toxins.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.
Discontinue use and consult with your doctor if any adverse reactions occur.
Keep out of reach of children
Brand IP Statement(s)
Pure Herbs, Ltd. Natural Herbal Extracts
FDA Statement of Identity
Dietary Supplement
General Statements
"No expense has been spared to provide the finest nature has to offer."
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Male Fern by Pure Herbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Male Fern by Pure Herbs
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.
Male Fern Root Extract
No knowninteractions
Male fern is an old herbal remedy that was once used as a powerful treatment to expel tapeworms. It is now considered outdated and potentially dangero...
Male Fern Root Extract monograph & interactionsOther (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
Male Fern by Pure Herbs Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Male Fern. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Male Fern, from the product label.
Pure Herbs
See all Pure Herbs products- Name
- Pure Herbs, Ltd.
- City
- Sterling Heights
- State
- MI
- Phone Number
- (800) 860-4372
- Web Address
- www.pureherbs.com
Male Fern by Pure Herbs: Common Questions
Does Male Fern by Pure Herbs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is male fern used for?
Can I take male fern if I'm pregnant or breastfeeding?
What are the side effects of male fern?
Why is male fern considered unsafe?
Are there drug interactions with male fern?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Male Fern is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Male Fern’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Male Fern's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Male Fern 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC