Marshmallow Select Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Marshmallow Select against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Marshmallow Select is a dietary supplement by Moss Nutrition with 2 active ingredients. Its ingredients are commonly taken for sore throat and cough, heartburn and stomach upset, mouth ulcers and digestive complaints.Based on those ingredients, 2,121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Marshmallow root powder, GutGard Deglycyrrhizinated Licorice root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Marshmallow Select by Moss Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Marshmallow Select by Moss Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Marshmallow Select by Moss Nutrition
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 2 of its 2 active ingredients.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 2 of the 2 matched ingredients can interact with medications — Marshmallow, Licorice.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications; lithium.
- For scale: 2,122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 2 of 2.
- General safety write-ups exist for 2 of 2.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Marshmallow Select, straight from the product label.
| Brand | Moss Nutrition |
|---|---|
| Barcode (UPC) | M135 |
| Net contents | 176 Gram(s); 6.2 oz. |
| Market status | Off market |
| Date entered into DSLD | Apr 25, 2019 |
| DSLD ID | 188771 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Marshmallow Select by Moss Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| GutGard Deglycyrrhizinated Licorice root extract | 150 mg | -- |
| organic Marshmallow root powder | 3770 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: 1 tablespoon per day in divided doses (1.5 level teaspoons AM & PM) or as directed by your healthcare professional. Mix with 8 oz water or other liquid.
Contents may settle, stir gently prior to use.
Precautions
Warning: If taking medication, pregnant or nursing consult a physician before using.
Keep out of reach of children.
Brand IP Statement(s)
GutGard is a registered trademark of Natural Remedies PVT. LTD.
M Professional Supplements Est. 1991
Formula
With GutGard DGL
FDA Statement of Identity
Dietary Supplement
Formulation
Does not contain gluten.
Storage
Store sealed in a cool, dry place.
General
V.0518.2
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Marshmallow Select by Moss Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Marshmallow Select by Moss Nutrition
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.5 Tbsp Dosage formPowder Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
GutGard Deglycyrrhizinated Licorice root extract
Interacts with1,040 drugs
Licorice root is a traditional remedy used for sore throats, coughs, and digestive complaints, but solid human evidence is limited for most uses. Regu...
GutGard Deglycyrrhizinated Licorice root extract monograph & interactionsOrganic Marshmallow root powder
Interacts with2,040 drugs
Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats,...
Organic Marshmallow root powder monograph & interactionsMarshmallow Select by Moss Nutrition Drug Interactions
Marshmallow Select contains 2 ingredients, and 2 of them have known drug interactions. Altogether they interact with 2,121 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Marshmallow Select?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Marshmallow Select interact with 2,121 drugs. Click any drug to see the details.
2 of the 2 ingredients in Marshmallow Select interact with drugs. Each result below shows which ingredient is responsible. organic Marshmallow root powder GutGard Deglycyrrhizinated Licorice root extract
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Marshmallow Select — through 1 ingredient. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Marshmallow Select — through 1 ingredient. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Marshmallow Select — through 1 ingredient. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Marshmallow Select — through 1 ingredient. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Marshmallow Select — through 1 ingredient. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Marshmallow Select — through 1 ingredient. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Abciximab interactionAcamprosateCampral
How Acamprosate interacts with Marshmallow Select — through 1 ingredient. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Marshmallow Select — through 1 ingredient. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Marshmallow Select — through 1 ingredient. Tap an ingredient for the detail:
Organic Marshmallow Root PowderAnticoagulant/antiplatelet Drugs, Oral Drugs Minor
Interaction Summary
Theoretically, marshmallow flower might have antiplatelet effects.
Read the full Organic Marshmallow Root Powder + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Marshmallow Select — through 1 ingredient. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen interactionGutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Gutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Aspirin interactionOrganic Marshmallow Root PowderAnticoagulant/antiplatelet Drugs, Oral Drugs Minor
Interaction Summary
Theoretically, marshmallow flower might have antiplatelet effects.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Aspirin interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Gutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionOrganic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Butalbital interactionGutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Gutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Butalbital, Codeine interactionOrganic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Butalbital, Codeine Phosphate interactionGutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, ChlorzoxazoneAcetazone Forte, Extra Strength Tylenol Aches & Strains, Parafon Forte
How Acetaminophen, Chlorzoxazone interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Chlorzoxazone interactionGutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Chlorzoxazone interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Gutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Chlorzoxazone, Codeine interactionOrganic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Codeine interactionGutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Gutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Codeine, Doxylamine interactionOrganic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Codeine, Methocarbamol interactionGutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dexbrompheniramine, PseudoephedrineSinadrin Plus
How Acetaminophen, Dexbrompheniramine, Pseudoephedrine interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Gutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Dexbrompheniramine, Pseudoephedrine interactionOrganic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Dexbrompheniramine, Pseudoephedrine interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Gutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Dichloralantipyrine, Isometheptene interactionOrganic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Dichloralphenazone, Isometheptene interactionGutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Gutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Dichlorophenazone, Isometheptane interactionOrganic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Diphenhydramine interactionGutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Gutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionOrganic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, Doxylamine, PseudoephedrineEx Strength Tylenol Sinus Nighttime
How Acetaminophen, Doxylamine, Pseudoephedrine interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Organic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Doxylamine, Pseudoephedrine interactionGutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Doxylamine, Pseudoephedrine interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Gutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Meperidine interactionOrganic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Meperidine interactionAcetaminophen, MethocarbamolRobaxacet
How Acetaminophen, Methocarbamol interacts with Marshmallow Select — through 2 ingredients. Tap an ingredient for the detail:
Gutgard Deglycyrrhizinated Licorice Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Gutgard Deglycyrrhizinated Licorice Root Extract + Acetaminophen, Methocarbamol interactionOrganic Marshmallow Root PowderOral Drugs Minor
Interaction Summary
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Organic Marshmallow Root Powder + Acetaminophen, Methocarbamol interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Marshmallow Select with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Marshmallow root powder
Lithium
Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.
Anticoagulant/Antiplatelet Drugs
Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.
Oral Drugs
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.
GutGard Deglycyrrhizinated Licorice root extract
Antihypertensive Drugs
Theoretically, licorice might reduce the effects of antihypertensive drugs.
In human research, licorice increases blood pressure in a dose-dependent manner.
Cisplatin (Platinol-Aq)
Theoretically, licorice might reduce the effects of cisplatin.
In animal research, licorice diminished the therapeutic efficacy of cisplatin.
Corticosteroids
Theoretically, concomitant use of licorice and corticosteroids might increase the side effects of corticosteroids.
Case reports suggest that concomitant use of licorice and oral corticosteroids, such as hydrocortisone, can potentiate the duration of activity and increase blood levels of corticosteroids. Additionally, in one case report, a patient with neurogenic orthostatic hypertension stabilized on fludrocortisone 0.1 mg twice daily developed pseudohyperaldosteronism after recent consumption of large amounts of black licorice.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2B6.
In vitro research shows that licorice extract and glabridin, a licorice constituent, inhibit CYP2B6 isoenzymes. Licorice extract from the species G. uralensis seems to inhibit CYP2B6 isoenzymes to a greater degree than G. glabra extract in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2B6; however, these interactions have not yet been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2C19.
In vitro, licorice extracts from the species G. glabra and G. uralensis inhibit CYP2C19 isoenzymes in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C19; however, this interaction has not yet been reported in humans.
Cytochrome P450 2C8 (Cyp2C8) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2C8.
In vitro, licorice extract from the species G. glabra and G. uralensis inhibits CYP2C8 isoenzymes. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C8; however, this interaction has not yet been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP2C9.
There is conflicting evidence about the effect of licorice on CYP2C9 enzyme activity. In vitro research shows that extracts from the licorice species G. glabra and G. uralensis moderately inhibit CYP2C9 isoenzymes. However, evidence from an animal model shows that licorice extract from the species G. uralensis can induce hepatic CYP2C9 activity. Until more is known, licorice should be used cautiously in people taking CYP2C9 substrates.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Pharmacokinetic research shows that the licorice constituent glycyrrhizin, taken in a dosage of 150 mg orally twice daily for 14 days, modestly decreases the area under the concentration-time curve of midazolam by about 20%. Midazolam is a substrate of CYP3A4, suggesting that glycyrrhizin modestly induces CYP3A4 activity. Animal research also shows that licorice extract from the species G. uralensis induces CYP3A4 activity. However, licorice extract from G. glabra species appear to inhibit CYP3A4-induced metabolism of testosterone in vitro. It is thought that the G. glabra inhibits CYP3A4 due to its constituent glabridin, which is a moderate CYP3A4 inhibitor in vitro and not present in other licorice species. Until more is known, licorice should be used cautiously in people taking CYP3A4 substrates.
Digoxin (Lanoxin)
Theoretically, concomitant use of licorice with digoxin might increase the risk of cardiac toxicity.
Overuse or misuse of licorice with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.
Diuretic Drugs
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Overuse of licorice might compound diuretic-induced potassium loss. In one case report, a 72-year-old male with a past medical history of hypertension, type 2 diabetes, hyperlipidemia, arrhythmia, stroke, and hepatic dysfunction was hospitalized with severe hypokalemia and uncontrolled hypertension due to pseudohyperaldosteronism. This was thought to be provoked by concomitant daily consumption of a product containing 225 mg of glycyrrhizin, a constituent of licorice, and hydrochlorothiazide 12.5 mg for 1 month.
Estrogens
Theoretically, licorice might increase or decrease the effects of estrogen therapy.
Theoretically, licorice might interfere with estrogen therapy due to estrogenic and anti-estrogenic effects.
Loop Diuretics
Theoretically, loop diuretics might increase the mineralocorticoid effects of licorice.
Theoretically, loop diuretics might enhance the mineralocorticoid effects of licorice by inhibiting the enzyme that converts cortisol to cortisone; however, bumetanide (Bumex) does not appear to have this effect.
Midazolam (Versed)
Theoretically, licorice might decrease levels of midazolam.
In humans, the licorice constituent glycyrrhizin appears to moderately induce the metabolism of midazolam. This is likely due to induction of cytochrome P450 3A4 by licorice. Until more is known, licorice should be used cautiously in people taking midazolam.
P-Glycoprotein Substrates
Theoretically, licorice might decrease the absorption of P-glycoprotein substrates.
In vitro research shows that licorice can increase P-glycoprotein activity.
Paclitaxel (Abraxane, Onxol)
Theoretically, licorice might decrease plasma levels and clinical effects of paclitaxel.
Multiple doses of licorice taken concomitantly with paclitaxel might reduce the effectiveness of paclitaxel. Animal research shows that licorice 3 grams/kg given orally for 14 days before intravenous administration of paclitaxel decreases the exposure to paclitaxel and increases its clearance. Theoretically, this occurs because licorice induces cytochrome P450 3A4 enzymes, which metabolize paclitaxel. Notably, a single dose of licorice did not affect exposure or clearance of paclitaxel.
Warfarin (Coumadin)
Theoretically, licorice might decrease plasma levels and clinical effects of warfarin.
Licorice seems to increase metabolism and decrease levels of warfarin in animal models. This is likely due to induction of cytochrome P450 2C9 (CYP2C9) metabolism by licorice. Advise patients taking warfarin to avoid taking licorice.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that licorice induces CYP1A2 enzymes.
Methotrexate (Trexall, Others)
Theoretically, licorice might increase levels of methotrexate.
Animal research suggests that intravenous administration of glycyrrhizin, a licorice constituent, and high-dose methotrexate may delay methotrexate excretion and increase systemic exposure, leading to transient elevations in liver enzymes and total bilirubin. This interaction has not yet been reported in humans.
Brand information
Manufacturer and brand details for Marshmallow Select, from the product label.
Moss Nutrition
See all Moss Nutrition products- Name
- Moss Nutrition Products, Inc.
- Street Address
- 380 Russell Street
- City
- Hadley
- State
- MA
- ZipCode
- 01035
- Phone Number
- 800-851-5444
- Web Address
- www.mossnutrition.com
Marshmallow Select by Moss Nutrition: Common Questions
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Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Marshmallow Select’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Licorice
Interacts with 1,040 drugsLicorice root is a traditional remedy used for sore throats, coughs, and digestive complaints, but solid human evidence is limited for most uses. Regular licorice contains glycyrrhizin, whic...
Read the full Licorice monograph → Herb & supplement monographMarshmallow
Interacts with 2,040 drugsMarshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...
Read the full Marshmallow monograph →Sources & How We Checked
Marshmallow Select's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 97 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Licorice 92 references
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC