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Dietary supplement

Healthy Arteries Ingredients & Drug Interactions

by Terry Naturally

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Healthy Arteries is a dietary supplement by Terry Naturally with 1 active ingredient. Its ingredients are commonly taken for vein health and chronic venous insufficiency, leg ulcers, peripheral artery disease and leg pain.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Mesoglycan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Healthy Arteries by Terry Naturally

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Healthy Arteries is a single-ingredient supplement containing mesoglycan, a substance extracted from animal tissue that's been studied for its effects on blood flow and vessel health. The capsule also contains inactive ingredients including microcrystalline cellulose, hydroxypropyl methylcellulose, silica, and an organic rice extract blend.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: artery strength and healthy circulation.
  • We looked for evidence on: Atherosclerosis, Cerebrovascular disease, Chronic venous insufficiency (CVI), Peripheral arterial disease (PAD), Venous leg ulcers, Venous thromboembolism (VTE) — and 4 related terms.
  • The strongest evidence on file: Mesoglycan is rated "Possibly Effective" for Cerebrovascular disease (Natural Medicines).
  • Also on file: Mesoglycan is rated "Possibly Effective" for Peripheral arterial disease (PAD), Venous leg ulcers.
  • Also on file: Mesoglycan is rated "Possibly Ineffective" for Venous thromboembolism (VTE).

Mesoglycan is rated possibly effective for cerebrovascular disease (blood flow problems affecting the brain), peripheral arterial disease (narrowed arteries in the legs and feet), and venous leg ulcers. It's rated possibly ineffective for preventing stroke and venous thromboembolism (blood clots in veins).

The evidence supporting these uses is not yet conclusive, so talk with your doctor about whether this ingredient fits your specific situation.

The evidence, ingredient by ingredient Mesoglycan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mesoglycan is generally well tolerated when taken by mouth. In clinical studies, some people reported nausea, vomiting, stomach pain, dyspepsia, heartburn, headache, diarrhea, and skin reactions.

One concern is that mesoglycan comes from raw animal tissues collected at slaughterhouses — products made from contaminated or diseased organs could present a health risk, though this is uncommon with reputable manufacturers. The safety data advises against use during pregnancy and while breastfeeding.

There isn't enough information to know either way, so talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Mesoglycan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Mesoglycan.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking this product if you use any blood thinners (anticoagulants) such as warfarin, heparin, clopidogrel, aspirin, or enoxaparin, or any clot-busting drugs (thrombolytics) like streptokinase or alteplase. Both groups interact at Moderate severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Healthy Arteries may be worth considering if you have peripheral arterial disease or cerebrovascular disease and you're looking to support blood flow — but the evidence is not yet conclusive. If you take any blood thinner or clot-busting medication, you'll need to check with your pharmacist first.

Pregnant women and those breastfeeding should avoid this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 28, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Healthy Arteries, straight from the product label.

Brand Terry Naturally
Barcode (UPC) 367703335038
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD May 28, 2019
DSLD ID 202382
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Healthy Arteries by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
367703335038
IngredientAmount% DV
Mesoglycan50 mg--

Other ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Silica, organic Rice extract blend

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Money-back guarantee Artery strength & healthy circulation Supports the strength, integrity, and flexibility of blood vessels Provides crucial cardiovascular support throughout the body, including the heart and arteries, but also the delicate blood vessels in the eyes, legs, and brain.

Heart Eyes Legs Brain For your good health Terry

Complete artery and circulation support!

Healthy Arteries supports the entire cardiovascular system.

For additional support use with Terry Naturally Clinical OPC

Healthy circulation supports Heart Eyes Legs Brain

JC 34 91 + 3(5,6)EP BX33503.06

Suggested/Recommended/Usage/Directions

Recommendations: 1 capsule daily. For advanced support increase to 1 capsule twice daily.

Precautions

If pregnant or nursing, consult a healthcare practitioner before using.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

JC 34 91 + 3(5,6)EP L33503.03

Formula

Powerful Mesoglycan

Clinical research on Mesoglycan shows amazing benefits in many ways: Supports the strength, integrity, and flexibility of blood vessels Supports healthy blood circulation, above and beyond its artery-strengthening abilities Provides crucial cardiovascular support throughout the body, including the heart, arteries, and also the delicate blood vessels in the eyes, legs, and brain.

The Mesoglycan in Heatlhy Arteries supports blood vessels throughout your body for life-enhancing benefits you'll appreciate: Heart - Maintains strong and flexible arteries and blood vessels to keep your cardiovascular system running smoothly. Eyes - Supports the tiny, intricate blood vessels in the retina for healthy vision and focus. Legs - Provides important factors for veins to relieve tired, heavy legs. Brain - Supports the delicate blood vessels in the brain for clear, crucial support.

FDA Statement of Identity

Dietary Supplement

Formulation

No sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives. Non-GMO

Brand IP Statement(s)

Terry Naturally EuroPharma

See for yourself

Healthy Arteries by Terry Naturally label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Healthy Arteries by Terry Naturally

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Mesoglycan

Interacts with
122 drugs
50 mg per serving Form: Glycosaminoglycans

Mesoglycan is a blend of natural sugar-protein compounds (glycosaminoglycans, including heparan sulfate and dermatan sulfate) taken from animal tissue...

Mesoglycan monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Hydroxypropyl Methylcellulose, Silica, Organic Rice extract blend. These complete the product’s ingredient list but are not active constituents.

Interaction report

Healthy Arteries by Terry Naturally Drug Interactions

Want to check YOUR meds against Healthy Arteries?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Healthy Arteries with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mesoglycan2 drug types · 122 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, combined use might increase bleeding risk. However, human evidence suggests that mesoglycan has profibrinolytic activity without affecting coagulation. These agents include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence B
Thrombolytic Drugs

Theoretically, combined use might increase bleeding risk. These drugs include alteplase (Activase), anistreplase (Eminase), reteplase (Retevase), streptokinase (Streptase), and urokinase (Abbokinase).

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Healthy Arteries, from the product label.

Terry Naturally

See all Terry Naturally products
Name
EuroPharma, Inc.
City
Green Bay
State
WI
ZipCode
54311
Phone Number
(866) 807-2731
Web Address
EuroPharmaUSA.com
Pharmacist Counseling Corner

Healthy Arteries by Terry Naturally: Common Questions

Does Healthy Arteries by Terry Naturally interact with any medications?
Yes. Based on its ingredients, Healthy Arteries has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Healthy Arteries contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is mesoglycan?
Mesoglycan is a substance derived from animal tissue, typically collected from slaughterhouses. It's been studied for its effects on blood flow and may work by promoting clot breakdown.
Can I take this if I'm on aspirin or another blood thinner?
Mesoglycan may theoretically increase bleeding risk with blood thinners, though human evidence suggests the real-world risk is lower than theory predicts. Don't add this product to your routine without checking with your pharmacist first — they can review your specific medication and dose.
What side effects might I notice?
Some people report nausea, vomiting, stomach pain, heartburn, headache, or diarrhea when taking mesoglycan by mouth. Skin reactions have also been reported. Most people tolerate it well.
Is this safe during pregnancy or breastfeeding?
No — the safety data advises against use during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, planning to become pregnant, or nursing.
Does mesoglycan actually work for peripheral arterial disease?
It's rated possibly effective for peripheral arterial disease based on available research, but the evidence isn't conclusive yet. Talk with your doctor about how it fits into your overall treatment plan.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Healthy Arteries label
Sources

Sources & How We Checked

Healthy Arteries's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mesoglycan 26 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Nationwide alert on hallmark labs injectable adrenal cortex extract. FDA. Available at: www.fda.gov/bbs/topics/NEWS/NEW00539.html
  3. Laurora G, Cesarone MR, Belcaro G, et al. [Control of the progress of arteriosclerosis in high risk subjects treated with mesoglycan. Measuring the intima media]. Minerva Cardioangiol 1998;46:41-7.
  4. Raso AM, Maggio D, Trogolo M, et al. [Effectiveness of mesoglycan therapy in patients with ischemia of the lower limbs. Preliminary results of a new therapeutic protocol]. Minerva Cardioangiol 1997;45:383-92.
  5. Blardi P, Messa G, Puccetti L, et al. [Effects on the coagulation-fibrinolysis system of a single oral dose of mesoglycan at the beginning and at the end of a prolonged treatment in man]. Recenti Prog Med 1995;86:282-9.
  6. Lotti T, Celasco G, Tsampau D, et al. Mesoglycan treatment restores defective fibrinolytic potential in cutaneous necrotizing venulitis. Int J Dermatol 1993;32:368-71. PubMed
  7. Ambrosio LA, Marchese G, Filippo A, et al. The effect of mesoglycan in patients with cerebrovascular disease: a psychometric evaluation. J Int Med Res 1993;21:138-46. PubMed
  8. Orlandi G, Viapiano F, Massetani R, et al. Clinical-instrumental evaluation of the effects of mesoglycan sulphate in chronic vascular encephalopathy. Acta Neurol (Napoli) 1991;13:255-60.
  9. Abate G, Berenga A, Caione F, et al. [Controlled multicenter study on the therapeutic effectiveness of mesoglycan in patients with cerebrovascular disease]. Minerva Med 1991;82:101-5.
  10. Prandoni P, Cattelan AM, Carta M. [Long-term sequelae of deep venous thrombosis of the legs. Experience with mesoglycan]. Ann Ital Med Int 1989;4:378-85.
  11. Cazzato G, Zorzon M, Mase G, et al. [Mesoglycan in acute focal cerebral ischemia]. Riv Neurol 1989;59:121-6.
  12. Vittoria A, Messa GL, Frigerio C, et al. Effect of a single dose of mesoglycan on the human fibrinolytic system, and the profibrinolytic action of nine daily doses. Int J Tissue React 1988;10:261-6.
  13. Postiglione A, De Simone B, Rubba P, et al. Effect of oral mesoglycan on plasma lipoprotein concentration and on lipoprotein lipase activity in primary hyperlipoproteinemia. Pharmacol Res Commun 1984;16:1-8. PubMed
  14. Arosio E, Ferrari G, Santoro L, et al. A placebo-controlled, double-blind study of mesoglycan in the treatment of chronic venous ulcers. Eur J Vasc Endovasc Surg 2001;22:365-72. PubMed
  15. Nenci, G. G., Gresele, P., Ferrari, G., Santoro, L., and Gianese, F. Treatment of intermittent claudication with mesoglycan--a placebo-controlled, double-blind study. Thromb.Haemost. 2001;86(5):1181-1187. DOI
  16. Messa, G., Blardi, P., La Placa, G., Puccetti, L., and Ghezzi, A. [Effects of 2 single oral doses of mesoglycan on the coagulation-fibrinolysis system in man. A pharmacodynamic study]. Recenti Prog.Med. 1995;86(7-8):272-281.
  17. Laurora, G., Ambrosoli, L., Cesarone, M. R., De Sanctis, M. T., Incandela, L., Marelli, C., and Belcaro, G. Treatment of intermittent claudication with defibrotide or mesoglycan. A double blind study. Panminerva Med. 1994;36(2):83-86.
  18. Laurora, G., Cesarone, M. R., De Sanctis, M. T., Incandela, L., and Belcaro, G. Delayed arteriosclerosis progression in high risk subjects treated with mesoglycan. Evaluation of intima-media thickness. J.Cardiovasc.Surg.(Torino) 1993;34(4):313-318.
  19. Pacella E, Pacella F, Turchetti P, et al. A pilot clinical study on the effectiveness of mesoglycan against diabetic retinopathy. Clin Ter. 2012;163(1):19-22.
  20. Viliani T, Scarselli M, Pieri A, Gatti M, Santini M, Pasquetti P. Pharmacological treatment of mechanical edema: a randomized controlled trial about the effects of mesoglycan. Eur J Phys Rehabil Med. 2009;45(1):21-9.
  21. Gossetti B, Antignani PL, Jabbour J, Martinelli O. Flow-mediated dilation benefits of mesoglycan in peripheral artery disease. Int Angiol. 2015;34(4):398-406.
  22. Duque-Estrada B, Vincenzi C, Misciali C, Tosti A. Alopecia secondary to mesotherapy. J Am Acad Dermatol. 2009;61(4):707-9. PubMed
  23. Gallo G, Mistrangelo M, Passera R, et al. Efficacy of mesoglycan in pain control after excisional hemorrhoidectomy: a pilot comparative prospective multicenter study. Gastroenterol Res Pract. 2018;2018:6423895. PubMed
  24. Neri G, Marcelli V, Califano L, Glicover Investigators. Assessment of the effect of mesoglycan in the treatment of audiovestibular disorders of vascular origin. Int J Immunopathol Pharmacol. 2018;32:2058738418773833. PubMed
  25. Valvano A, Bosso G, Apuzzi V, Riccone F, Saccá L, Oliviero U. Mesoglycan improves vascular reactivity and insulin sensitivity in patients with metabolic syndrome. Atherosclerosis. 2015;243(2):407-13. PubMed
  26. Gallo G, Di Saverio S, Clerico G, et al. Mesoglycan for pain control after open excisional haemorrhoidectomy (MeHAEMO): an observational multicentre study on behalf of the Italian Society of Colorectal Surgery (SICCR). BMC Surg. 2020 Oct 22;20(1):251.

See these in context on the Mesoglycan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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