Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Mood Support Fast Dissolves Delicious Orange Cream Ingredients & Drug Interactions

by Healthy Delights

Mood Support Fast Dissolves Delicious Orange Cream label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Mood Support Fast Dissolves Delicious Orange Cream against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Mood Support Fast Dissolves Delicious Orange Cream is a dietary supplement by Healthy Delights with 2 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis, correcting vitamin d deficiency, immune system support.Based on those ingredients, 943 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D, 5-HTP. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Mood Support Fast Dissolves Delicious Orange Cream by Healthy Delights

Ask about any prescription or over-the-counter medication and we check it for interactions with Mood Support Fast Dissolves Delicious Orange Cream by Healthy Delights — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Mood Support Fast Dissolves Delicious Orange Cream by Healthy Delights

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 20, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains 2 active ingredients: vitamin D and 5-HTP. Vitamin D supports bone health and calcium balance, and your body makes it from sunlight—this supplement provides it in concentrated form.

5-HTP is a compound your brain uses to make serotonin, a neurotransmitter involved in mood and sleep. The product also contains several inactive ingredients—fillers, flavoring, and a sweetener (rebaudioside A)—that help it dissolve quickly and taste like orange cream.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: improve mood.
  • We looked for evidence on: Depression, Anxiety, Generalized anxiety disorder (GAD), Low mood, Emotional well-being.
  • The strongest evidence on file: 5-htp is rated "Possibly Effective" for Depression (Natural Medicines).
  • Also on file: 5-htp is rated "Insufficient Reliable Evidence To Rate" for Anxiety.
  • Also on file: Vitamin D is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD), Depression.

Vitamin D is effective for rickets, osteomalacia (soft bone disease), renal bone disease, hypoparathyroidism, and familial hypophosphatemia—inherited conditions affecting calcium and bone. 5-HTP is possibly effective for depression, though the evidence is limited.

For panic disorder, Alzheimer's disease, and cerebellar ataxia, the evidence isn't established in our data. Effectiveness ratings vary, so talk with your doctor about whether this product matches your needs.

The evidence, ingredient by ingredient Vitamin D 5-htp

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin D is generally well tolerated at recommended doses, though very high doses over time can cause toxicity—symptoms include high blood calcium (hypercalcemia), bone loss in adults, and slowed growth in children. It's often used during pregnancy at recommended amounts, but only under your doctor's guidance; breastfeeding at recommended doses is considered acceptable, though confirm with your doctor before taking higher amounts.

5-HTP is generally well tolerated short-term orally, but the data advises against it during pregnancy and breastfeeding because there isn't enough safety information. Common 5-HTP side effects include stomach pain, loss of appetite, dizziness, diarrhea, drowsiness, fatigue, headache, sleep problems, nausea, and vomiting—severity is often dose-dependent and may improve with time.

Rare serious effects include aggression, hallucinations, and mania.

Side effects, ingredient by ingredient Vitamin D 5-htp

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — 5-htp, Vitamin D.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications; Parkinson's medications.
  • For scale: 944 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you use digoxin or other heart medications (especially verapamil, diltiazem, and thiazide water pills), atorvastatin or other cholesterol drugs, Parkinson's medications like carbidopa, antidepressants or migraine drugs that work on serotonin, or sedating medications like sleep aids. These moderate-severity interactions need individual review of your doses and health situation.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Mood Support Fast Dissolves might help with depression (though evidence is limited) and provides vitamin D for bone health. If you take heart or blood pressure medications, cholesterol drugs, Parkinson's treatments, antidepressants, migraine medications, or sedating drugs, you need to check your exact medications with your pharmacist or doctor before starting this product.

Pregnancy and breastfeeding require personalized guidance—talk with your doctor or pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 21, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mood Support Fast Dissolves Delicious Orange Cream, straight from the product label.

Brand Healthy Delights
Barcode (UPC) 746888912447
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Oct 21, 2017
DSLD ID 79771
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mood Support Fast Dissolves Delicious Orange Cream by Healthy Delights, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Fast Dissolve Tablet(s)
Maximum serving Sizes:
1 Fast Dissolve Tablet(s)
Servings per container
60
UPC/BARCODE
746888912447
IngredientAmount% DV
Vitamin D2000 IU500%
5-HTP25 mg--

Other ingredients: Quick Melt Blend, Natural flavors, Citric Acid, Vegetable Magnesium Stearate, Silica, Turmeric, Rebaudioside A

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

30X faster than regular tablets No more pills - melts in your mouth!

Our Fast Dissolves melt in your mouth in seconds, so there are none of the common absorption problems or partially dissolved tablets that your body can’t use. A full 100% of your dietary supplement goes to work for you instantly!

Dissolution comparison table Goes to work in seconds! Fast Dissolves Less than 1 ming 30X faster Soft gels 20 min Regular tablets 30 min Average dissolution time

Melts in your mouth!

Improve your mood, delicious taste

Serotonin levels in the brain can affect mood, whether negatively or positively. One way to boost serotonin levels and improve mood is to supplement with Vitamin D. We all know you can get Vitamin D from the sun, but we also know the dangerous effects of too much sun.

Plus, thanks to the nature of fast dissolves, they make the vitamin D more bioavailable, meaning it’s readily used and easily absorbed by the body for utmost efficacy.

Dissolves quickly in your mouth – no pills!

New!

30X faster than regular tablets

Naturally flavored

Manufactured in the USA.

Do not use if safety seal is broken or missing.

Brand IP Statement(s)

Healthy Delights Fast Dissolves take supplements to a whole new level!

Healthy Delights Fast Dissolves are perfect for those constantly on-the-go or that have difficulty swallowing pills, plus they are incredibly delicious, so you will actually look forward to taking your supplements everyday!

Healthy Delights Mood Support Fast Dissolves are delicious tasting tablets that literally melt in your mouth – no need for the discomfort of swallowing pills!

Nothing so healthy ever tasted so great!

Formula

Our powerful formula combines 2,000 IU’s of vitamin D with 5-HTP known for its positive impact on mood.

Highly bioavailable 2,000 IU’s of vitamin D 5-HTP for natural mood support

With vitamin D & 5-HTP to help promote a positive mood

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults, as a dietary supplement take 1 fast dissolve tablet daily. For best results, allow tablet to dissolve in your mouth before swallowing.

Formulation

Does Not Contain: Artificial colors, dairy, nuts, preservatives, shellfish, soy, wheat, gluten.

Precautions

Consult a health care practitioner prior to use if you are pregnant or breastfeeding, taking any medications or have any medical conditions.

Keep out of the reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

B-91244-1

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Mood Support Fast Dissolves Delicious Orange Cream by Healthy Delights label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Mood Support Fast Dissolves Delicious Orange Cream label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Mood Support Fast Dissolves Delicious Orange Cream by Healthy Delights

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Fast Dissolve Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin D

Interacts with
715 drugs
2000 IU per serving Form: Cholecalciferol

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...

Vitamin D monograph & interactions

5-HTP

Interacts with
398 drugs
25 mg per serving Form: Griffonia simplicifolia

5-HTP is a compound your body uses to make serotonin, and people take it as a supplement hoping to improve mood, sleep, and headaches. Some early rese...

5-HTP monograph & interactions

Other (inactive) ingredients: Quick Melt Blend, Natural flavors, Citric Acid, Vegetable Magnesium Stearate, Silica, Turmeric, Rebaudioside A. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mood Support Fast Dissolves Delicious Orange Cream by Healthy Delights Drug Interactions

Want to check YOUR meds against Mood Support Fast Dissolves Delicious Orange Cream?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
943Drugs
477 Moderate 466 Minor

Ingredients driving the most interactions

Vitamin D 715
5-HTP 398

Individual Drug Interactions

The ingredients in Mood Support Fast Dissolves Delicious Orange Cream interact with 943 drugs. Click any drug to see the details.

2 of the 2 ingredients in Mood Support Fast Dissolves Delicious Orange Cream interact with drugs. Each result below shows which ingredient is responsible. Vitamin D 5-HTP

Each ingredient & the kinds of drugs it affects

For each ingredient in Mood Support Fast Dissolves Delicious Orange Cream with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin D8 drug types · 715 drugs

Aluminum

Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.

Likelihood Probable Evidence B
Atorvastatin (Lipitor)

Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.

Likelihood Probable Evidence B
Calcipotriene (Dovonex)

Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.

Likelihood Probable Evidence B
Thiazide Diuretics

Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.

Likelihood Probable Evidence D
Verapamil (Calan, Others)

Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.

Likelihood Possible Evidence D
Vitamin D full monograph & interactions

5-HTP3 drug types · 398 drugs

Carbidopa (Lodosyn)

Combining 5-HTP and carbidopa can increase the risk of serotonergic side effects.
Carbidopa is sometimes used with 5-HTP to minimize peripheral 5-HTP metabolism and boost the amount that reaches the brain. However, this combination might also increase the risk of some side effects including hypomania, restlessness, rapid speech, anxiety, insomnia, and aggressiveness. Combining carbidopa and 5-HTP might also increase the risk of scleroderma-like skin changes due to elevated serotonin levels.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, concomitant use of 5-HTP with medications that cause sedation might have additive effects.
In clinical trials, 5-HTP has been associated with drowsiness and somnolence.

Likelihood Possible Evidence D
Serotonergic Drugs

Combining serotonergic drugs with 5-HTP might cause additive serotonergic effects.
5-HTP can increase serotonin levels and cause serotonergic effects. Theoretically, combining serotonergic drugs with 5-HTP might increase the risk of serotonergic side effects, including serotonin syndrome and cerebral vasoconstrictive disorders. However, serotonin syndrome with 5-HTP has not yet been reported in humans. Monitor patients for signs of serotonin syndrome and other serotonergic side effects if using 5-HTP with serotonergic drugs.

Likelihood Possible Evidence D
5-HTP full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Mood Support Fast Dissolves Delicious Orange Cream, from the product label.

Healthy Delights

See all Healthy Delights products
Name
Healthy Natural Solutions
Street Address
11780 U.S. Highway One, Suite 400N
City
Palm Beach Gardens
State
FL
ZipCode
33408
Web Address
www.HealthyDelights.com
Pharmacist Counseling Corner

Mood Support Fast Dissolves Delicious Orange Cream by Healthy Delights: Common Questions

Does Mood Support Fast Dissolves Delicious Orange Cream by Healthy Delights interact with any medications?
Yes. Based on its ingredients, Mood Support Fast Dissolves Delicious Orange Cream has a known interaction with 943 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mood Support Fast Dissolves Delicious Orange Cream contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Vitamin D at recommended doses is often used during pregnancy and is acceptable while breastfeeding, but check with your doctor first. 5-HTP doesn't have enough safety data—the facts advise against it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist for personalized advice based on your situation.
What are the most common side effects of 5-HTP?
Stomach pain, loss of appetite, dizziness, diarrhea, drowsiness, fatigue, headache, sleep problems, nausea, and vomiting are most common. These are often dose-dependent—they may be worse when you start or increase your dose—and some people find they improve over time with continued use.
Does vitamin D really work for bone health?
Yes, vitamin D is effective for serious bone conditions like rickets, osteomalacia, renal bone disease, hypoparathyroidism, and familial hypophosphatemia. For general bone health in otherwise healthy people, the data we hold don't address that specifically—ask your doctor whether you need supplementation.
Can this help my depression?
5-HTP is possibly effective for depression, but the evidence is limited. If you're considering it for depression, talk with your doctor or mental health provider—especially if you're already taking antidepressants, because combining them with 5-HTP carries interaction risks.
What's the difference between vitamin D from this supplement and from sunlight?
Your skin makes vitamin D when exposed to sunlight, but a supplement provides it in a concentrated, measured dose. This product lets you control how much you get, which is important because very high doses over time can cause toxicity.
Are there any fillers or other inactive ingredients I should know about?
Yes—this product contains a quick melt blend, natural flavors, citric acid, magnesium stearate, silica, turmeric, and rebaudioside A (a sweetener). These are inactive ingredients that help the tablet dissolve and taste good; if you're sensitive to any of them, let your pharmacist know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mood Support Fast Dissolves Delicious Orange Cream label
Go deeper

The Full Monographs Behind Mood Support Fast Dissolves Delicious Orange Cream’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin D

Interacts with 715 drugs

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...

Read the full Vitamin D monograph → Herb & supplement monograph

5-htp

Interacts with 398 drugs

5-HTP is a compound your body uses to make serotonin, and people take it as a supplement hoping to improve mood, sleep, and headaches. Some early research is promising, but the overall evide...

Read the full 5-htp monograph →
Sources

Sources & How We Checked

Mood Support Fast Dissolves Delicious Orange Cream's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 58 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin D 26 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Tatro DS, ed. Drug Interactions Facts. Facts and Comparisons Inc., St. Louis, MO. 1999.
  3. Koutkia P, Chen TC, Holick MF. Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med 2001;345:66-7. PubMed
  4. Bar-Or D, Yoel G. Calcium and calciferol antagonize effect of verapamil in atrial fibrillation. Br Med J 1981;282:1585-6.
  5. Demontis R, Leflon A, Fournier A, et al. 1 alpha(OH) vitamin D3 increases plasma aluminum in hemodialyzed patients taking AI(OH)3. Clin Nephrol 1986;26:146-9.
  6. Crowe M, Wollner L, Griffiths RA. Hypercalcemia following vitamin D and thiazide therapy in the elderly. Practitioner 1984;228:312-3.
  7. Parfitt AM. Thiazide-induced hypercalcemia in vitamin D-treated hypoparathyroidism. Ann Intern Med 1972;77:557-63. PubMed
  8. Thiazide diuretics and the risk of osteoporosis. Pharmacist's Letter/Prescriber's Letter 2003;19(11):191105.
  9. Moon J. The role of vitamin D in toxic metal absorption. J Am Coll Nutr 1994;13:559-64.
  10. Demontis R, Reissi D, Noel C, et al. Indirect clinical evidence that 1alphaOH vitamin D<SUB>3</SUB> increases the intestinal absorption of aluminum. Clin Nephrol 1989;31:123-7.
  11. Adler AJ, Berlyne GM. Duodenal aluminum absorption in the rat: effect of vitamin D. Am J Physiol 1985;249:G209-13. PubMed
  12. Schwartz JB. Effects of vitamin D supplementation in atorvastatin-treated patients: A new drug interaction with an unexpected consequence. Clin Pharmacol Ther 2009;85:198-203. PubMed
  13. Dietary reference intakes for calcium and vitamin D. Institute of Medicine, November 30, 2010. Available at: http://www.iom.edu/~/media/Files/Report%20Files/2010/Dietary-Reference-Intakes-for-Calcium-and-Vitamin-D/Vitamin%20D%20and%20Calcium%202010%20Repo
  14. Cox KA, Dunn MA. Aluminum toxicity alters the regulation of calbindin-D28k protein and mRNA expression in chick intestine. J Nutr 2001;131:2007-13. PubMed
  15. Escribano, J., Balaguer, A., Pagone, F., Feliu, A., and Roque, I. Figuls. Pharmacological interventions for preventing complications in idiopathic hypercalciuria. Cochrane.Database.Syst.Rev. 2009;(1):CD004754. PubMed
  16. Carlton, S., Clopton, D., and Cappuzzo, K. A. Vitamin D deficiency: appropriate replenishment therapies and the effects of vitamin D toxicity. Consult Pharm 2010;25(3):171-177. PubMed
  17. Wang, H., Xia, N., Yang, Y., and Peng, D. Q. Influence of vitamin D supplementation on plasma lipid profiles: a meta-analysis of randomized controlled trials. Lipids Health Dis. 2012;11:42. PubMed
  18. Turner AN, Carr Reese P, Fields KS, Anderson J, Ervin M, Davis JA, Fichorova RN, Roberts MW, Klebanoff MA, Jackson RD. A blinded, randomized controlled trial of high-dose vitamin D supplementation to reduce recurrence of bacterial vaginosis. Am J Obstet G PubMed
  19. Weiner M, Epstein FH. Signs and symptoms of electrolyte disorders. Yale J Biol Med. 1970;43(2):76-109.
  20. Lappe J, Watson P, Travers-Gustafson D, Recker R, Garland C, Gorham E, Baggerly K, McDonnell SL. Effect of Vitamin D and Calcium Supplementation on Cancer Incidence in Older Women: A Randomized Clinical Trial. JAMA. 2017 Mar 28;317(12):1234-1243. PubMed
  21. Roth DE, Leung M, Mesfin E, Qamar H, Watterworth J, Papp E. Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials. BMJ. 2017;359:j5237. PubMed
  22. Murai IH, Fernandes AL, Sales LP, et al. Effect of a single high dose of vitamin D3 on hospital length of stay in patients with moderate to severe COVID-19: A randomized clinical trial. JAMA. 2021.
  23. Wang Z, Schuetz EG, Xu Y, Thummel KE. Interplay between vitamin D and the drug metabolizing enzyme CYP3A4. J Steroid Biochem Mol Biol 2013;136:54-8. PubMed
  24. Doyle D, Browne U, Brickley A, Murphy D. Vitamin D-induced hypercalcaemia and acute kidney injury in sarcoidosis. BMJ Case Rep 2023;16(1):e250580. PubMed
  25. Williamson A, Martineau AR, Sheikh A, Jolliffe D, Griffiths CJ. Vitamin D for the management of asthma. Cochrane Database Syst Rev 2023;2(2):CD011511. PubMed
  26. Kinesya E, Santoso D, Gde Arya N, et al. Vitamin D as adjuvant therapy for diabetic foot ulcers: Systematic review and meta-analysis approach. Clin Nutr ESPEN 2023;54:137-143. PubMed

See these in context on the Vitamin D monograph →

5-htp 32 references
  1. Birdsall TC. 5-Hydroxytryptophan: A Clinically-Effective Serotonin Precursor. Altern Med Rev 1998;3:271-80.
  2. Michelson D, Page SW, Casey R, et al. An eosinophilia-myalgia syndrome related disorder associated with exposure to L-5-hydroxytryptophan. J Rheumatol 1994;21:2261-5.
  3. Cangiano C, Ceci F, Cancino A, et al. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. Am J Clin Nutr 1992;56:863-7. PubMed
  4. U.S. Food and Drug Administration. Impurities confirmed in dietary supplement 5-hydroxy-L-tryptophan. FDA Talk Paper, August 31, 1998; T98-48.
  5. Sternberg EM, Van Woert MH, Young SN, et al. Development of a scleroderma-like illness during therapy with L-5-hydroxytryptophan and carbidopa. N Engl J Med 1980;303:782-7. PubMed
  6. Poldinger W, Calanchini B, Schwarz W. A functional-dimensional approach to depression: serotonin deficiency as a target syndrome in a comparison of 5-hydroxytryptophan and fluvoxamine. Psychopathology 1991;24:53-81.
  7. Ribeiro CA. L-5-Hydroxytryptophan in the prophylaxis of chronic tension-type headache: a double-blind, randomized, placebo-controlled study. Headache 2000;40:451-6.
  8. U. S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Nutritional Products, Labeling, and Dietary Supplements. Information Paper on L-Tryptophan and 5-hydroxy-L-tryptophan, February 2001.
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