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Dietary supplement

Mullein Leaf 1000 mg Ingredients & Drug Interactions

by Double Wood Supplements

Capsule Category: Botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Mullein Leaf 1000 mg is a dietary supplement by Double Wood Supplements with 1 active ingredient. Its ingredients are commonly taken for cough and chest congestion, sore throat, bronchitis and respiratory irritation.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Mullein Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Mullein Leaf 1000 mg by Double Wood Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: mullein leaf extract at 1,000 mg per capsule. Mullein is a plant that's been used traditionally to support respiratory health.

The capsule itself is made from hypromellose, an inactive ingredient that forms the capsule shell.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Mullein's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: respiratory health and cough support.
  • We looked for evidence on: Asthma, Bronchitis, Cough, Influenza, Pneumonia, chest congestion — and 2 related terms.
  • The closest evidence on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Bronchitis (Natural Medicines).
  • Also on file: Mullein is rated "Insufficient Reliable Evidence To Rate" for Asthma, Cough, Influenza, Pneumonia.

The evidence for mullein leaf in our data shows insufficient reliable evidence to rate its effectiveness for bronchitis, asthma, cough, migraine headache, or diarrhea. That means the studies we have aren't strong enough yet to say whether it works for these uses.

If you're considering mullein for a specific health concern, talk with your pharmacist or doctor about what the current research actually supports.

The evidence, ingredient by ingredient Mullein

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mullein leaf extract is generally well tolerated for short-term use, though human safety data are limited. The main caution comes from a small number of case reports describing skin irritation (dermatitis) after direct contact with the plant or from breathing in plant dust — usually in people who also reacted to other plants.

The safety data advises against using mullein during pregnancy, and there isn't enough information to consider it safe while breastfeeding. If you're pregnant, planning to become pregnant, or nursing, talk with your doctor or pharmacist before taking this supplement.

Side effects, ingredient by ingredient Mullein

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Mullein.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any blood-thinning or antiplatelet medications you take — aspirin, warfarin, clopidogrel, and similar drugs — with the medication checker on this page, as mullein leaf extract may have minor effects on blood clotting.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Mullein leaf may be worth trying if you're looking for respiratory support, though the evidence for it isn't established yet in our data. If you take blood thinners or antiplatelet medications, check your specific drugs with the tool on this page first.

For pregnancy, breastfeeding, or any ongoing health condition, talk with your pharmacist or doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Mullein Leaf 1000 mg, straight from the product label.

Brand Double Wood Supplements
Barcode (UPC) 850033272437
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 315684
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Mullein Leaf 1000 mg by Double Wood Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
850033272437
IngredientAmount% DV
Mullein Leaf Extract1000 mg--

Other ingredients: Hypromellose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Product Information: Mullein Leaf is a plan used for centuries in herbal remedies. The flowers and leaves have been used by herbalists for many different health benefits. Mullein leaf may contain high amounts of saponins, gycosides, flavonoids, and minerals.

Mullein Leaf 1000 mg per serving

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement take 1 serving per day, with or without food.

Storage

Storage: Store in a cool, dark place. Do not freeze or expose to moisture or heat above room temperature after opening.

Seals/Symbols

Proudly Manufactured in the USA Made with Non-GMO Ingredients

Formulation

Made with Non-GMO Ingredients Gluten Free

No fillers

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Precautions

Warning: Consult your physician before use.

Do not use Mullein Leaf if you are pregnant, nursing, or are under 18 years of age.

Do not use Mullein Leaf if you are pregnant, nursing, or are under 18 years of age.

Discontinue use and consult your doctor immediately if any adverse reactions occur. Do not use Mullein Leaf and operate heavy machinery until you know how it affects you.

Keep out of reach of children.

Do not exceed 4 capsules per day.

See for yourself

Mullein Leaf 1000 mg by Double Wood Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Mullein Leaf 1000 mg by Double Wood Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Mullein Leaf Extract

Interacts with
122 drugs
1000 mg per serving

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality huma...

Mullein Leaf Extract monograph & interactions

Other (inactive) ingredients: Hypromellose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Mullein Leaf 1000 mg by Double Wood Supplements Drug Interactions

Want to check YOUR meds against Mullein Leaf 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
122Drugs
122 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Mullein Leaf 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Mullein Leaf Extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.

Likelihood Unlikely Evidence A
The maker

Brand information

Manufacturer and brand details for Mullein Leaf 1000 mg, from the product label.

Double Wood Supplements

See all Double Wood Supplements products
Name
Double Wood LLC
Street Address
3510 Scotts Ln Ste 219
City
Philadelphia
State
PA
ZipCode
19129-15173
Web Address
www.doublewoodsupplements.com
Pharmacist Counseling Corner

Mullein Leaf 1000 mg by Double Wood Supplements: Common Questions

Does Mullein Leaf 1000 mg by Double Wood Supplements interact with any medications?
Yes. Based on its ingredients, Mullein Leaf 1000 mg has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Mullein Leaf 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
The safety data advises against mullein during pregnancy. For breastfeeding, there isn't enough data to know either way. Either way, talk with your doctor or pharmacist for personalized advice before taking it.
Does mullein leaf actually work for cough or bronchitis?
In our data, the evidence for mullein in cough, bronchitis, and asthma is rated insufficient — meaning the studies aren't strong enough yet to say it works. That doesn't mean it doesn't; it just means we can't confirm it from the research we have.
What side effects should I watch for?
Mullein is generally well tolerated. A small number of case reports describe skin irritation after direct contact with the plant or from breathing in plant dust. Human safety data overall are limited, so stick to short-term use and tell your pharmacist if anything unusual comes up.
Is there anything else in the capsule besides mullein?
The capsule shell is made from hypromellose, which is an inactive ingredient that holds the mullein extract together. That's it — no other fillers or additives.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Mullein Leaf 1000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Mullein Leaf 1000 mg label
Go deeper

The Full Monographs Behind Mullein Leaf 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Mullein Leaf 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mullein 2 references
  1. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
  2. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

See these in context on the Mullein monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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