No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 4 ingredients. Check your meds →
Dietary supplement

Multi Collagen Ingredients & Drug Interactions

by Natural Elements

Capsule Category: Amino Acid/protein
No known interaction
The interaction bottom line No known interaction

Multi Collagen is a dietary supplement by Natural Elements with 4 active ingredients. Its ingredients are commonly taken for skin health and wrinkles, joint pain and osteoarthritis, bone health.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Multi Collagen by Natural Elements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (2,025 mg) without saying how much of each component you get.

Natural Elements Multi Collagen contains four active ingredients — three are hydrolyzed collagen sources (from fish, beef, and pork) and one is eggshell membrane collagen peptides. All are forms of broken-down collagen, a structural protein your body uses for skin, joints, and connective tissue.

The product also contains inactive ingredients: a vegetable capsule and rice flour.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: skin, hair, nail, and joint health.
  • We looked for evidence on: Aging skin, Wrinkled skin, Androgenic alopecia, Brittle nails, Joint pain, Knee pain — and 4 related terms.
  • The strongest evidence on file: Collagen Peptides is rated "Possibly Effective" for Aging skin (Natural Medicines).
  • Also on file: Collagen Peptides is rated "Insufficient Reliable Evidence To Rate" for Androgenic alopecia, Brittle nails, Osteoarthritis, Knee pain, and more.

The evidence for collagen peptides shows mixed results. For aging skin and dry skin, the data suggests they are possibly effective — meaning there's some promising research, but it's not definitive.

For muscle strength, the evidence points toward possibly ineffective. The research on acne and athletic performance is too thin to rate either way.

If you're taking this mainly for skin support, the data offers modest encouragement; if you're hoping for stronger muscles or athletic gains, the case is weaker.

The evidence, ingredient by ingredient Collagen Peptides

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Collagen peptides are generally well tolerated as a dietary protein, with side effects that are mild and uncommon. Some people report nausea, indigestion (dyspepsia), diarrhea, or gas, but these are rare.

If you're pregnant, the safety data isn't robust enough to be reassuring — talk with your doctor before using. For breastfeeding, there's little safety data, so caution is advised; check with your doctor or pharmacist about whether it's right for you.

One collagen source in this product (fish) and another (bovine) were not checked for safety, so any safety concerns tied to those sources are not yet on file.

Side effects, ingredient by ingredient Collagen Peptides

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the collagen peptides and porcine collagen in this product. However, we could not check the hydrolyzed fish collagen and hydrolyzed bovine collagen, so confirm with your doctor or pharmacist that this product is safe to combine with your specific medications.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Multi Collagen by Natural Elements may be worth considering if you're interested in supporting aging or dry skin, since the evidence for collagen peptides is cautiously positive for those uses. No interactions are documented for the ingredients we could check, but two collagen sources remain unchecked — run your medications through the tool on this page and talk with your doctor or pharmacist before starting, especially if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Multi Collagen, straight from the product label.

Brand Natural Elements
Barcode (UPC) 731717960520
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD May 22, 2021
DSLD ID 247635
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Multi Collagen by Natural Elements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
60
UPC/BARCODE
731717960520
IngredientAmount% DV
hydrolyzed Fish Collagen0 NP--
hydrolyzed Bovine Collagen0 NP--
Proprietary Blend2025 mg--
Eggshell Membrane Collagen Peptides0 NP--
hydrolyzed Porcine Collagen0 NP--

Other ingredients: Vegetable Capsule, Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Adults take three capsules one or more times daily with 8 ounces of water or juice.

Precautions

Not intended for children.

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, individuals with a known medical condition or any medications should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, individuals with a known medical condition or any medications should consult a physician before using this or any dietary supplement.

Contains: Egg, fish

Formulation

Uses & Benefits: This Multi Collagen contains 5 types of collagen. Type I & III helps skin elasticity with hair & nail growth. Type II contains glucosamine, which promotes healthy joint and tendons. Type V supports surface cells for glowing skin as well as digestive health. Type X helps bones with support of new bone formation and healthy joints.

Grass-fed Pasture-raised

Gluten-free No artificial ingredients Made with Non-GMO ingredients

Healthy skin & hair Supports joints & bone Helps digestive & immune

Contains No Added: Milk, tree nuts, wheat, peanuts, soy.

General Statements

Only the highest quality collagen

100 day money back guarantee Satisfaction Guarantee We offer a full refund on the purchase price of your order (minus shipping) within 100 days of purchase.

Formula

PF Paleo Friendly KF Keto Friendly

5 types of food source collagen Type I, II, III, V, and X

Seals/Symbols

GMP Quality Good Manufacturing Practice Made in the USA

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Multi Collagen by Natural Elements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Multi Collagen by Natural Elements

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

2025 mg per serving

Other (inactive) ingredients: Vegetable Capsule, Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Multi Collagen by Natural Elements Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Multi Collagen. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Multi Collagen, from the product label.

Natural Elements

See all Natural Elements products
Name
Natural Elements US
City
Phoenix
State
AZ
Web Address
www.naturalelementsus.com
Pharmacist Counseling Corner

Multi Collagen by Natural Elements: Common Questions

Does Multi Collagen by Natural Elements interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Multi Collagen. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Multi Collagen contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does collagen really help with wrinkles and dry skin?
The evidence suggests collagen peptides may help with both — they're rated possibly effective for aging skin and dry skin. That means there's some encouraging research, but it's not ironclad. Your results will likely vary depending on how long you take it and your individual skin.
Can I take this if I'm pregnant?
Collagen peptides haven't been well studied in pregnancy, so there isn't enough safety data to say either way. Talk with your doctor before using this product while pregnant — they can weigh the pros and cons based on your personal situation.
What side effects might I experience?
Nausea, indigestion, diarrhea, and gas are possible, but they're rare. Collagen peptides are generally well tolerated as a dietary protein, so most people won't notice anything.
Will this help me build muscle or improve my athletic performance?
The evidence doesn't support collagen for muscle strength, which is rated possibly ineffective. For athletic performance, there simply isn't enough reliable research to say either way.
Is it okay to take while breastfeeding?
There's very little safety data for collagen during breastfeeding, so caution is advised. Check with your doctor or pharmacist before starting — they can help you decide if it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Multi Collagen is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Multi Collagen label
Go deeper

The Full Monographs Behind Multi Collagen’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Multi Collagen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Collagen Peptides 2 references
  1. Trc T, Bohmová J. Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). Int Orthop. 2011;35(3):341-8. PubMed
  2. Evans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021;20(3):825-834. PubMed

See these in context on the Collagen Peptides monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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