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Dietary supplement

N-Fuzed Testosterone Ingredients & Drug Interactions

by Harmonic Innerprizes

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

N-Fuzed Testosterone is a dietary supplement by Harmonic Innerprizes with 3 active ingredients. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eurycoma longifolia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of N-Fuzed Testosterone by Harmonic Innerprizes

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Blend (Herb/Botanical)” is a proprietary blend — the label gives one combined amount (50 mcg) without saying how much of each component you get.

N-Fuzed Testosterone is a liquid supplement with 3 active ingredients: Eurycoma longifolia (also called tongkat ali), Maca lepidium (a Peruvian root), and Ptychopetalum olacoides (muira puama, a South American plant). The product also contains inactive ingredients including distilled water, grapefruit seed extract, glycerin, and vitamin C to preserve and deliver the blend.

Eurycoma longifolia is traditionally used to support sexual desire and has been studied in aging men. Maca and muira puama are herbal ingredients with a long history in traditional medicine, though their modern supplement uses haven't been firmly established by science.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: promote testosterone in normal range.
  • We looked for evidence on: Age-related testosterone deficiency, Sexual desire, Erectile dysfunction (ED), Male Infertility, Muscle strength, testosterone levels — and 2 related terms.
  • The strongest evidence on file: Eurycoma Longifolia is rated "Possibly Effective" for Sexual desire (Natural Medicines).
  • Also on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Sexual desire, Age-related testosterone deficiency, Male infertility.
  • Also on file: Muira Puama is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED).

The evidence on this product's ingredients is limited. Eurycoma longifolia is possibly effective for sexual desire based on available studies, but is rated possibly ineffective for athletic performance and has insufficient evidence for back pain, osteoporosis, or diabetes.

Maca and muira puama both lack reliable evidence for their intended uses — we don't have established ratings for either ingredient's effectiveness at treating sexual dysfunction or erectile dysfunction. If sexual health is your goal, talk with your doctor about whether the evidence here is enough for you, or if other options might be better studied.

The evidence, ingredient by ingredient Eurycoma Longifolia Maca Muira Puama

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Eurycoma longifolia is generally tolerated in short-term studies, but long-term safety is uncertain and product quality varies. One concern is that if the herb raises testosterone above normal levels, there's a risk of testosterone-related side effects including acne, insulin resistance, and liver toxicity.

Maca is generally well tolerated as a food but has limited long-term safety data as a supplement; raw or uncooked maca may cause stomach pain. Muira puama has limited human safety data overall.

During pregnancy, Eurycoma longifolia, Maca, and muira puama all lack enough safety information — the data advises against using them. The same caution applies to breastfeeding: there isn't enough reliable safety information for any of the three active ingredients, so it's best to avoid this product while nursing.

Talk with your doctor or pharmacist before taking this if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Eurycoma Longifolia Maca Muira Puama

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking N-Fuzed Testosterone, check with your doctor or pharmacist if you take propranolol (Inderal) or any other medications — Eurycoma longifolia can reduce propranolol's effectiveness. The herb also may theoretically raise levels of drugs processed through liver enzymes CYP1A2, CYP2C19, or CYP2A6, and may further increase testosterone if you're already on testosterone therapy.

Use the medication checker on this page or speak with your own pharmacist to confirm your specific drugs are safe to combine.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

N-Fuzed Testosterone may appeal to you if you're interested in herbal support for sexual function, though the evidence for maca and muira puama is weak. The most important step is checking whether Eurycoma longifolia will interact with your medications — especially propranolol or drugs broken down by your liver.

Don't take this during pregnancy or while breastfeeding. Talk it over with your doctor or pharmacist before you start, especially if you're on any regular medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about N-Fuzed Testosterone, straight from the product label.

Brand Harmonic Innerprizes
Barcode (UPC) 640627120028
Net contents 8 fl. Oz.; 236 mL
Market status On market
Date entered into DSLD Dec 22, 2017
DSLD ID 81644
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for N-Fuzed Testosterone by Harmonic Innerprizes, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Teaspoon(s)
Maximum serving Sizes:
1 Teaspoon(s)
Servings per container
48
UPC/BARCODE
640627120028
IngredientAmount% DV
Eurycoma longifolia0 NP--
Proprietary Blend (Herb/Botanical)50 mcg--
Maca lepidium0 NP--
Ptychopetalum olacoides0 NP--

Other ingredients: distilled Water, Grapefruit seed extract, Glycerin, Vitamin C, May contain:

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Combines highly effective herbs and through a new, state-of-the-art process infuses the essences of these same botanicals into the crystalline structure of the aqueous medium. N-fuzed Testosterone has been clinically tested and shown to raises testosterone levels in 30-60 days. Very low testosterone levels may take longer to achieve normalcy.

Promotes testosterone in the normal range Clinically tested

N-fuzed essences

Formula

For men only.

May contain lactose.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

2015 HarmonicInnerprizes, Inc.

FDA Statement of Identity

Dietary Supplement

Precautions

May contain lactose.

Warning: Consult your physician before use if you are pregnant, lactating, have a medical condition or are taking any medication.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 teaspoon before breakfast and 1 teaspoon before bed time.

Storage

Store at room temperatures, away from electromagnetic interference such as televisions, computers, and microwave ovens.

See for yourself

N-Fuzed Testosterone by Harmonic Innerprizes label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in N-Fuzed Testosterone by Harmonic Innerprizes

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Teaspoon(s) Dosage formLiquid Servings per container48 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend (Herb/Botanical)

50 mcg per serving

Other (inactive) ingredients: Distilled Water, Grapefruit seed extract, Glycerin, Vitamin C, May contain:. These complete the product’s ingredient list but are not active constituents.

Interaction report

N-Fuzed Testosterone by Harmonic Innerprizes Drug Interactions

Want to check YOUR meds against N-Fuzed Testosterone?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
248Drugs
3 Moderate 245 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in N-Fuzed Testosterone with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Eurycoma longifolia5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for N-Fuzed Testosterone, from the product label.

Harmonic Innerprizes

See all Harmonic Innerprizes products
Name
Harmonic Innerprizes, Inc.
City
Henderson
State
NV
ZipCode
89053
Phone Number
1.888.667.4300
Web Address
Harmonicinnerprizes.com
Pharmacist Counseling Corner

N-Fuzed Testosterone by Harmonic Innerprizes: Common Questions

Does N-Fuzed Testosterone by Harmonic Innerprizes interact with any medications?
Yes. Based on its ingredients, N-Fuzed Testosterone has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
N-Fuzed Testosterone contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Eurycoma longifolia, and why is it in this product?
Eurycoma longifolia, also called tongkat ali, is a Southeast Asian plant root traditionally used to support sexual desire. Research in aging men shows it may raise testosterone levels modestly. It's the primary active ingredient in this testosterone-support formula.
Can I take this if I'm on propranolol?
No — not without checking with your doctor first. Eurycoma longifolia can lower propranolol levels by about 29%, which could reduce how well it controls your blood pressure or heart condition. Talk with your doctor or pharmacist before combining them.
What are the side effects of Eurycoma longifolia?
If the herb raises your testosterone beyond the normal range, you might experience testosterone-related side effects like acne, insulin resistance, or liver problems. The ingredient is generally tolerated short-term, but long-term safety isn't well established.
Is this safe to take while pregnant or breastfeeding?
No. All three active ingredients in this product — Eurycoma longifolia, Maca, and muira puama — lack enough safety data during pregnancy and breastfeeding, so the data advises against using them during these times. Talk with your doctor or pharmacist if you're pregnant, planning pregnancy, or nursing.
Does maca or muira puama really improve sexual function?
The evidence isn't established yet. Both ingredients have insufficient reliable evidence for sexual dysfunction or erectile dysfunction in the data we hold. While they're used traditionally, modern studies haven't confirmed their effectiveness.
Can I take this with other testosterone products?
Eurycoma longifolia may theoretically add to testosterone levels if you're already on testosterone therapy. Check with your doctor or pharmacist before combining them to make sure the total is safe for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if N-Fuzed Testosterone is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

N-Fuzed Testosterone label
Sources

Sources & How We Checked

N-Fuzed Testosterone's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

Muira Puama 2 references
  1. Waynberg, J. and Brewer, S. Effects of Herbal vX on libido and sexual activity in premenopausal and postmenopausal women. Adv Ther 2000;17(5):255-262. PubMed
  2. Nguyen S, Rajfer J, Shaheen M. Safety and efficacy of daily Revactin in men with erectile dysfunction: a 3-month pilot study. Transl Androl Urol. 2018;7(2):266-73. PubMed

See these in context on the Muira Puama monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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