N-Fuzed Testosterone Ingredients & Drug Interactions
What is this page for?
First and foremost: checking N-Fuzed Testosterone against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
N-Fuzed Testosterone is a dietary supplement by Harmonic Innerprizes with 3 active ingredients. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eurycoma longifolia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against N-Fuzed Testosterone by Harmonic Innerprizes
Ask about any prescription or over-the-counter medication and we check it for interactions with N-Fuzed Testosterone by Harmonic Innerprizes — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of N-Fuzed Testosterone by Harmonic Innerprizes
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
N-Fuzed Testosterone is a liquid supplement with 3 active ingredients: Eurycoma longifolia (also called tongkat ali), Maca lepidium (a Peruvian root), and Ptychopetalum olacoides (muira puama, a South American plant). The product also contains inactive ingredients including distilled water, grapefruit seed extract, glycerin, and vitamin C to preserve and deliver the blend.
Eurycoma longifolia is traditionally used to support sexual desire and has been studied in aging men. Maca and muira puama are herbal ingredients with a long history in traditional medicine, though their modern supplement uses haven't been firmly established by science.
Does it work?
Moderate evidence
The evidence on this product's ingredients is limited. Eurycoma longifolia is possibly effective for sexual desire based on available studies, but is rated possibly ineffective for athletic performance and has insufficient evidence for back pain, osteoporosis, or diabetes.
Maca and muira puama both lack reliable evidence for their intended uses — we don't have established ratings for either ingredient's effectiveness at treating sexual dysfunction or erectile dysfunction. If sexual health is your goal, talk with your doctor about whether the evidence here is enough for you, or if other options might be better studied.
How safe is it?
Well-documented data
Eurycoma longifolia is generally tolerated in short-term studies, but long-term safety is uncertain and product quality varies. One concern is that if the herb raises testosterone above normal levels, there's a risk of testosterone-related side effects including acne, insulin resistance, and liver toxicity.
Maca is generally well tolerated as a food but has limited long-term safety data as a supplement; raw or uncooked maca may cause stomach pain. Muira puama has limited human safety data overall.
During pregnancy, Eurycoma longifolia, Maca, and muira puama all lack enough safety information — the data advises against using them. The same caution applies to breastfeeding: there isn't enough reliable safety information for any of the three active ingredients, so it's best to avoid this product while nursing.
Talk with your doctor or pharmacist before taking this if you're pregnant, planning to become pregnant, or breastfeeding.
Meds to double-check
Moderate interaction found
Before taking N-Fuzed Testosterone, check with your doctor or pharmacist if you take propranolol (Inderal) or any other medications — Eurycoma longifolia can reduce propranolol's effectiveness. The herb also may theoretically raise levels of drugs processed through liver enzymes CYP1A2, CYP2C19, or CYP2A6, and may further increase testosterone if you're already on testosterone therapy.
Use the medication checker on this page or speak with your own pharmacist to confirm your specific drugs are safe to combine.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
N-Fuzed Testosterone may appeal to you if you're interested in herbal support for sexual function, though the evidence for maca and muira puama is weak. The most important step is checking whether Eurycoma longifolia will interact with your medications — especially propranolol or drugs broken down by your liver.
Don't take this during pregnancy or while breastfeeding. Talk it over with your doctor or pharmacist before you start, especially if you're on any regular medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about N-Fuzed Testosterone, straight from the product label.
| Brand | Harmonic Innerprizes |
|---|---|
| Barcode (UPC) | 640627120028 |
| Net contents | 8 fl. Oz.; 236 mL |
| Market status | On market |
| Date entered into DSLD | Dec 22, 2017 |
| DSLD ID | 81644 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for N-Fuzed Testosterone by Harmonic Innerprizes, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Eurycoma longifolia | 0 NP | -- |
| Proprietary Blend (Herb/Botanical) | 50 mcg | -- |
| Maca lepidium | 0 NP | -- |
| Ptychopetalum olacoides | 0 NP | -- |
Other ingredients: distilled Water, Grapefruit seed extract, Glycerin, Vitamin C, May contain:
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Combines highly effective herbs and through a new, state-of-the-art process infuses the essences of these same botanicals into the crystalline structure of the aqueous medium. N-fuzed Testosterone has been clinically tested and shown to raises testosterone levels in 30-60 days. Very low testosterone levels may take longer to achieve normalcy.
Promotes testosterone in the normal range Clinically tested
N-fuzed essences
Formula
For men only.
May contain lactose.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
2015 HarmonicInnerprizes, Inc.
FDA Statement of Identity
Dietary Supplement
Precautions
May contain lactose.
Warning: Consult your physician before use if you are pregnant, lactating, have a medical condition or are taking any medication.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take 1 teaspoon before breakfast and 1 teaspoon before bed time.
Storage
Store at room temperatures, away from electromagnetic interference such as televisions, computers, and microwave ovens.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
N-Fuzed Testosterone by Harmonic Innerprizes label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in N-Fuzed Testosterone by Harmonic Innerprizes
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Teaspoon(s) Dosage formLiquid Servings per container48 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend (Herb/Botanical)
Other (inactive) ingredients: Distilled Water, Grapefruit seed extract, Glycerin, Vitamin C, May contain:. These complete the product’s ingredient list but are not active constituents.
N-Fuzed Testosterone by Harmonic Innerprizes Drug Interactions
HelloPharmacist Interaction Report
N-Fuzed Testosterone by Harmonic Innerprizes contains Eurycoma longifolia, which interacts with medications.
The most serious concern is a moderate interaction with propranolol (Inderal), a beta-blocker used for high blood pressure and heart conditions — Eurycoma longifolia can reduce propranolol's levels and effectiveness by roughly 29% based on a clinical study.
Read the full breakdown — every affected drug type, severity by severity
Eurycoma longifolia may also theoretically increase levels of several other drug types through effects on liver enzymes (CYP1A2, CYP2C19, and CYP2A6 substrates), though these effects have only been seen in lab studies, not yet in people. There's also a minor theoretical interaction with testosterone itself — the herb may further raise testosterone levels beyond what the supplement alone provides.
Maca lepidium and Ptychopetalum olacoides (muira puama), the other two active ingredients, show no interactions documented in our data. Altogether, these interactions span 248 individual medications.
Before you start this product, search your exact medications in the tool on this page or talk with your doctor or pharmacist — especially if you take propranolol or any drug metabolized by those liver enzymes.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against N-Fuzed Testosterone?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in N-Fuzed Testosterone interact with 248 drugs. Click any drug to see the details.
1 of the 3 ingredients in N-Fuzed Testosterone interact with drugs. Each result below shows which ingredient is responsible. Eurycoma longifolia
Acetaminophen, PhenylpropanolamineTetra Caps
How Acetaminophen, Phenylpropanolamine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Acetaminophen, Phenylpropanolamine interactionAcetaminophen, Phenylpropanolamine, PhenyltoloxamineSinubid
How Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, PhenyltoloxaminePercogesic, Relagesic
How Acetaminophen, Phenyltoloxamine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Acetaminophen, Phenyltoloxamine interactionAcetaminophen, Phenyltoloxamine, SalicylamideLobac
How Acetaminophen, Phenyltoloxamine, Salicylamide interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Acetaminophen, Phenyltoloxamine, Salicylamide interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Acetaminophen, Propoxyphene interactionAcetaminophen, PseudoephedrineChildren's Tylenol Sinus, Dristan N.D., Non-Aspirin Sinus, Ornex, Ornex-Max, Sinutab +5 more
How Acetaminophen, Pseudoephedrine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Acetaminophen, Pseudoephedrine interactionAcetaminophen, Pseudoephedrine, TriprolidineActifed Plus ES
How Acetaminophen, Pseudoephedrine, Triprolidine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Acetaminophen, Pseudoephedrine, Triprolidine interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Eurycoma Longifolia + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Eurycoma Longifolia + Agomelatine interactionAmitriptylineElavil
How Amitriptyline interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Amitriptyline, Perphenazine interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Eurycoma Longifolia + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAnagrelideAgrylin
How Anagrelide interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Anagrelide interactionAsenapineSaphris, Secuado
How Asenapine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Asenapine interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Caffeine, Codeine Phosphate interactionAspirin, Caffeine, Dihydrocodeine BitartrateSynalgos DC
How Aspirin, Caffeine, Dihydrocodeine Bitartrate interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Caffeine, Dihydrocodeine Bitartrate interactionAspirin, Caffeine, Dover's PwdAcedoval, Dovacet
How Aspirin, Caffeine, Dover's Pwd interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Caffeine, Dover's Pwd interactionAspirin, Caffeine, HydrocodoneDamason-P
How Aspirin, Caffeine, Hydrocodone interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Caffeine, Hydrocodone interactionAspirin, Caffeine, Isobutylallylbarbituric Acid, PhenacetinLanorinal
How Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Caffeine, Isobutylallylbarbituric Acid, Phenacetin interactionAspirin, Caffeine, OrphenadrineInvagesic, Invagesic Forte, Norgesic, Norgesic Forte, Orphengesic, Orphengesic Forte
How Aspirin, Caffeine, Orphenadrine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Caffeine, Orphenadrine interactionAspirin, Caffeine, Phenacetin, PropoxypheneMargesic Comp. 65
How Aspirin, Caffeine, Phenacetin, Propoxyphene interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Caffeine, Phenacetin, Propoxyphene interactionAspirin, CarisoprodolSoma Compound
How Aspirin, Carisoprodol interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Eurycoma Longifolia + Aspirin, Carisoprodol interactionAspirin, Carisoprodol, Codeine PhosphateSoma Compound w/ Codeine
How Aspirin, Carisoprodol, Codeine Phosphate interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Eurycoma Longifolia + Aspirin, Carisoprodol, Codeine Phosphate interactionAspirin, OmeprazoleYosprala
How Aspirin, Omeprazole interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 2c19 (cyp2c19) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
Read the full Eurycoma Longifolia + Aspirin, Omeprazole interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with N-Fuzed Testosterone — through 1 ingredient. Tap an ingredient for the detail:
Eurycoma LongifoliaCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
Read the full Eurycoma Longifolia + Aspirin, Pentazocine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in N-Fuzed Testosterone with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Eurycoma longifolia
Propranolol (Inderal)
Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.
Testosterone
Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.
Brand information
Manufacturer and brand details for N-Fuzed Testosterone, from the product label.
Harmonic Innerprizes
See all Harmonic Innerprizes products- Name
- Harmonic Innerprizes, Inc.
- City
- Henderson
- State
- NV
- ZipCode
- 89053
- Phone Number
- 1.888.667.4300
- Web Address
- Harmonicinnerprizes.com
N-Fuzed Testosterone by Harmonic Innerprizes: Common Questions
Does N-Fuzed Testosterone by Harmonic Innerprizes interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is Eurycoma longifolia, and why is it in this product?
Can I take this if I'm on propranolol?
What are the side effects of Eurycoma longifolia?
Is this safe to take while pregnant or breastfeeding?
Does maca or muira puama really improve sexual function?
Can I take this with other testosterone products?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if N-Fuzed Testosterone is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind N-Fuzed Testosterone’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Eurycoma Longifolia
Interacts with 248 drugsEurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....
Read the full Eurycoma Longifolia monograph → Herb & supplement monographMaca
Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire and some menopause symptoms, but the evide...
Read the full Maca monograph → Herb & supplement monographMuira Puama
Muira puama is a Brazilian plant traditionally used as an aphrodisiac and general tonic, often nicknamed 'potency wood.' Human research is very limited, so its benefits are not well proven,...
Read the full Muira Puama monograph →Sources & How We Checked
N-Fuzed Testosterone's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Eurycoma Longifolia 4 references
- Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
- Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
- Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
- Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent
Maca 1 reference
- Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed
Muira Puama 2 references
- Waynberg, J. and Brewer, S. Effects of Herbal vX on libido and sexual activity in premenopausal and postmenopausal women. Adv Ther 2000;17(5):255-262. PubMed
- Nguyen S, Rajfer J, Shaheen M. Safety and efficacy of daily Revactin in men with erectile dysfunction: a 3-month pilot study. Transl Androl Urol. 2018;7(2):266-73. PubMed
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