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Dietary supplement

No. 22 A Sea Vegetation Ingredients & Drug Interactions

by Wachters'

No. 22 A Sea Vegetation label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking No. 22 A Sea Vegetation against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

No. 22 A Sea Vegetation is a dietary supplement by Wachters' with 1 active ingredient. Its ingredients are commonly taken for preventing iodine deficiency, supporting thyroid hormone production, general energy and metabolism support.Based on those ingredients, 7 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Iodine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against No. 22 A Sea Vegetation by Wachters'

Ask about any prescription or over-the-counter medication and we check it for interactions with No. 22 A Sea Vegetation by Wachters' — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of No. 22 A Sea Vegetation by Wachters'

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: iodine, a mineral that your body needs for thyroid health and other functions. There are no other active or inactive ingredients listed.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: energy and stamina with endocrine support.
  • We looked for evidence on: Iodine deficiency, thyroid function, metabolism, endocrine health.
  • The strongest evidence on file: Iodine is rated "Likely Effective" for Iodine deficiency (Natural Medicines).

Iodine is likely effective for preventing radiation exposure to the thyroid and for treating iodine deficiency. It's possibly effective for oral mucositis (mouth sores) and periodontitis (gum disease), though the evidence for those uses is less established.

The evidence, ingredient by ingredient Iodine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Iodine is well tolerated at normal dietary amounts, but high doses can cause thyroid problems. In pregnancy and breastfeeding, adequate iodine matters — but you should use only the amount your doctor advises and avoid high-dose products.

Some people can have hypersensitivity reactions to iodine itself; symptoms include swelling, rash, fever, and rarely, severe reactions like anaphylaxis. Long-term use or large amounts have been reported to cause acnelike skin lesions.

Most side effects at normal doses are mild — nausea, headache, metallic taste, or abdominal upset — but thyroid changes and goiter can develop with excess intake.

Side effects, ingredient by ingredient Iodine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Iodine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 7 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take lithium, any antithyroid medication, or amiodarone. All three have Moderate interactions with iodine that require thyroid function monitoring.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is useful if you have iodine deficiency or need thyroid protection after radiation exposure. If you take lithium, antithyroid drugs, or amiodarone, you'll need to talk it over with your doctor or pharmacist first because iodine can interfere with how they work.

Stick to the dose your healthcare provider recommends and avoid high-dose products on your own.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about No. 22 A Sea Vegetation, straight from the product label.

Brand Wachters'
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD May 24, 2013
DSLD ID 21945
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Qualified Health, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Organic, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for No. 22 A Sea Vegetation by Wachters', sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
100
IngredientAmount% DV
Iodine225 mcg150%

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Sea Vegetation is good for everybody. It does not deplete the body of energy as some reducing programs can, rather, it may increase energy and stamina by working in cooperation with the endocrine glands. Naturally high In Iodine, an essential mineral for the regulation of energy through its effect on the metabolism and also necessary for the proper function of the thyroid gland. Our blend has been specifically created using up to 15 different species of sea vegetation from around the world. Our species are selected for their rich nutritional profile of naturally occurring vitamins, minerals, amino acids, polysaccharides, dietary fibers, lipids, micronutrients and over 64 trace minerals. Purity and quality are of equal importance, if they do not pass our quality tests they do not make it into Wachters' Exclusive Blend, putting it in a class by itself. It is this incredible quality Blend that makes our product superior to anyone else's on the market. Researchers have discovered what Wachters' has known for decades, the combination of various species of sea vegetables can provide a wide range of nutrients known for valuable heath benefits that are often lacking in the diets of many individuals. *

ORGANIC SEA PRODUCTS

No heat, moisture or chemicals are used in preparation of No. 22.

Made in U.S.A.

FDA Disclaimer Statement

* This Statement has not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Since 1932 W Borne From The Sea

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

"Wachters' Exclusive Blend of Sea Vegetation"(R) is a registered trademark of Wachters'Organic Sea Products and is an exclusive combination of multi-marine plant sources.

No. 22, Wachters' Exclusive Blend of Sea Vegetation(R) is low calorie, nearly fat -free and one of the richest sources of nutrients from the sea.

Formulation

Wachters' Organic Sea Products dietary supplements contain no preservatives, yeast, artificial colorings, artificial flavorings, sugar, starch or animal products.

Suggested/Recommended/Usage/Directions

Recommended Dosage: As a dietary supplement, take 1 tablet of No. 22, Sea Vegetation daily. Take with 8 oz. of water or juice. For optimum results, use this product with other Wachters' products.

Precautions

THIS PRODUCT WAS SEALED FOR YOUR PROTECTION. DO NOT USE IF SEAL HAS BEEN TAMPERED WITH.

Keep out of reach of children

General

Code #5140

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

No. 22 A Sea Vegetation by Wachters' label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

No. 22 A Sea Vegetation label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in No. 22 A Sea Vegetation by Wachters'

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container100 Amounts shown are per serving.

Iodine

Interacts with
7 drugs
225 mcg per serving Form: Wachters' Exclusive Blend of Sea Vegetation(R)

Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements...

Iodine monograph & interactions
Interaction report

No. 22 A Sea Vegetation by Wachters' Drug Interactions

Want to check YOUR meds against No. 22 A Sea Vegetation?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
7Drugs
7 Moderate

Ingredients driving the most interactions

Iodine 7

Individual Drug Interactions

The ingredients in No. 22 A Sea Vegetation interact with 7 drugs. Click any drug to see the details.

1 of the 1 ingredient in No. 22 A Sea Vegetation interact with drugs. Each result below shows which ingredient is responsible. Iodine

Each ingredient & the kinds of drugs it affects

For each ingredient in No. 22 A Sea Vegetation with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Iodine3 drug types · 7 drugs

Amiodarone (Cordarone)

Combining iodine with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with iodine might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.

Likelihood Probable Evidence D
Antithyroid Drugs

Iodine might alter the effects of antithyroid drugs.
Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking iodine while using antithyroid drugs could alter the effects of the antithyroid drugs.

Likelihood Probable Evidence D
Lithium

Combining iodine with lithium might have additive hypothyroid effects.
Lithium can inhibit thyroid function. Several case reports suggest that concomitant use of lithium and potassium iodide can reduce thyroid function in otherwise healthy adults. Monitor thyroid function.

Likelihood Probable Evidence D
Iodine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for No. 22 A Sea Vegetation, from the product label.

Wachters'

See all Wachters' products
Phone Number
1-800-682-7100
Pharmacist Counseling Corner

No. 22 A Sea Vegetation by Wachters': Common Questions

Does No. 22 A Sea Vegetation by Wachters' interact with any medications?
Yes. Based on its ingredients, No. 22 A Sea Vegetation has a known interaction with 7 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
No. 22 A Sea Vegetation contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Your body does need iodine in pregnancy and while breastfeeding, but the data advises using only the amount your doctor recommends and avoiding high-dose products. Talk with your doctor or pharmacist about the right dose for you.
What does iodine do in the body?
Iodine is essential for your thyroid gland to make hormones that control your metabolism and growth. It's also involved in other body functions and can protect the thyroid if you're exposed to radiation.
Can I have an allergic reaction to this product?
Rare but serious hypersensitivity reactions to iodine itself have been reported, with symptoms like swelling, rash, fever, and in severe cases, anaphylaxis. If you've had reactions to iodine-containing medications or foods in the past, mention that to your doctor or pharmacist before taking this.
What side effects might I notice?
At normal doses, the most common mild effects are nausea, headache, metallic taste, or abdominal upset. High amounts or long-term use can cause thyroid problems, goiter, or acnelike skin lesions — which is why sticking to the recommended dose matters.
Does this product actually work for iodine deficiency?
Yes — iodine is likely effective for treating iodine deficiency. It's also likely effective for protecting your thyroid after radiation exposure. For mouth sores and gum disease, the evidence is weaker but possibly effective.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

No. 22 A Sea Vegetation label
Go deeper

The Full Monographs Behind No. 22 A Sea Vegetation’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Iodine

Interacts with 7 drugs

Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements help when you are truly deficient, but...

Read the full Iodine monograph →
Sources

Sources & How We Checked

No. 22 A Sea Vegetation's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Iodine 26 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
  3. Ghent WR, Eskin BA, Low DA, Hill LP. Iodine replacement in fibrocystic disease of the breast. Can J Surg 1993;36:453-60.
  4. Potassium iodide for nuclear exposure. Pharmacist's Letter/Prescriber's Letter 2001;17(12):171214.
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cabezas C, Bustamante B, Holgado W, Begue RE. Treatment of cutaneous sporotrichosis with one daily dose of potassium iodide. Pediatr Infect Dis J 1996;15:352-4. PubMed
  7. Sterling JB, Heymann WR. Potassium iodide in dermatology: a 19th century drug for the 21st century-uses, pharmacology, adverse effects, and contraindications. J Am Acad Dermatol 2000;43:691-7. PubMed
  8. Yarrington CD, Pearce EN. Dietary iodine in pregnancy and postpartum. Clin Obstet Gynecol 2011;54:459-70. PubMed
  9. Goel, S., Mandhani, A., Srivastava, A., Kapoor, R., Gogoi, S., Kumar, A., and Bhandari, M. Is povidone iodine an alternative to silver nitrate for renal pelvic instillation sclerotherapy in chyluria? BJU.Int 2004;94(7):1082-1085. PubMed
  10. Teng, W., Shan, Z., Teng, X., Guan, H., Li, Y., Teng, D., Jin, Y., Yu, X., Fan, C., Chong, W., Yang, F., Dai, H., Yu, Y., Li, J., Chen, Y., Zhao, D., Shi, X., Hu, F., Mao, J., Gu, X., Yang, R., Tong, Y., Wang, W., Gao, T., and Li, C. Effect of iodine int
  11. Crawford, B. A., Cowell, C. T., Emder, P. J., Learoyd, D. L., Chua, E. L., Sinn, J., and Jack, M. M. Iodine toxicity from soy milk and seaweed ingestion is associated with serious thyroid dysfunction. Med J Aust. 10-4-2010;193(7):413-415. PubMed
  12. Ohkuma, M. Molluscum contagiosum treated with iodine solution and salicylic acid plaster. Int J Dermatol. 1990;29(6):443-445. PubMed
  13. Connelly KJ, Boston BA, Pearce EN, Sesser D, Snyder D, Braverman LE, Pino S, LaFranchi SH. Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion. J Pediatr. 2012 Oct;161(4):760-2. PubMed
  14. Kasahara T, Narumi S, Okasora K, Takaya R, Tamai H, Hasegawa T. Delayed onset congenital hypothyroidism in a patient with DUOX2 mutations and maternal iodine excess. Am J Med Genet A. 2013 Jan;161A(1):214-7.
  15. Murcia M, Rebagliato M, Iñiguez C, Lopez-Espinosa MJ, Estarlich M, Plaza B, Barona-Vilar C, Espada M, Vioque J, Ballester F. Effect of iodine supplementation during pregnancy on infant neurodevelopment at 1 year of age. Am J Epidemiol. 2011 Apr 1;173(7):8 PubMed
  16. Sang Z, Wang PP, Yao Z, Shen J, Halfyard B, Tan L, Zhao N, Wu Y, Gao S, Tan J, Liu J, Chen Z, Zhang W. Exploration of the safe upper level of iodine intake in euthyroid Chinese adults: a randomized double-blind trial. Am J Clin Nutr. 2012 Feb;95(2):367-73 PubMed
  17. Speeckaert MM, Speeckaert R, Wierckx K, Delanghe JR, Kaufman JM. Value and pitfalls in iodine fortification and supplementation in the 21st century. Br J Nutr. 2011 Oct;106(7):964-73. PubMed
  18. Yun SE, Kang Y, Bae EJ, Hwang K, Jang HN, Cho HS, Chang SH, Park DJ. Iodine-induced thyrotoxic hypokalemic paralysis after ingestion of Salicornia herbace. Ren Fail. 2014 Apr;36(3):461-3.
  19. Iodine Hypersensitivity. Pharmacist's Letter/Prescriber's Letter 2011; 27(5):270504.
  20. Hammel JA, Selby JC. Pustular eruption in a patient with cancer treated with complementary and alternative medicine. JAMA Dermatology 2017 October; E1. doi: 10.1001/jamadermatol.2017.3749. [Epub ahead of print] PubMed
  21. Gil GS, Smith BW, Guerra JR, Williams WT. Acute Delirium in a Hypothyroid Patient Precipitated by Iodine Supplements Use. Am J Ther. 2018;25(6):e717-e718. PubMed
  22. Hamby T, Kunnel N, Dallas JS, Wilson DP. Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism. J Pediatr Endocrinol Metab. 2018;31(9):1061-1064. PubMed
  23. Censi S, Watutantrige-Fernando S, Groccia G, et al. The Effects of Iodine Supplementation in Pregnancy on Iodine Status, Thyroglobulin Levels and Thyroid Function Parameters: Results from a Randomized Controlled Clinical Trial in a Mild-to-Moderate Iodine
  24. Rovner MS, Wolf BJ, Rubin M, et al. Instillation of 5% Povidone-Iodine Ophthalmic Drops Decreases the Respiratory Rate in Children Undergoing Strabismus Surgery: A Randomized Controlled Trial. J Pediatr Ophthalmol Strabismus. 2019;56(6):378-382. PubMed
  25. Guenezan J, Garcia M, Strasters D, et al. Povidone Iodine Mouthwash, Gargle, and Nasal Spray to Reduce Nasopharyngeal Viral Load in Patients With COVID-19: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2021;147(4):400-401. PubMed
  26. Li F, Wan S, Zhang L, et al. A Meta-Analysis of the Effect of Iodine Excess on the Intellectual Development of Children in Areas with High Iodine Levels in their Drinking Water. Biol Trace Elem Res 2022;200(4):1580-1590. PubMed

See these in context on the Iodine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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