Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Non-GMO Pre-Workout West Coast Citrus Ingredients & Drug Interactions

by Propello Life

Non-GMO Pre-Workout West Coast Citrus label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Non-GMO Pre-Workout West Coast Citrus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Non-GMO Pre-Workout West Coast Citrus is a dietary supplement by Propello Life with 5 active ingredients. Its ingredients are commonly taken for improving high-intensity exercise performance, building muscle strength and size, sports and athletic training.Based on those ingredients, 756 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are natural Caffeine, L-Citrulline Malate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Non-GMO Pre-Workout West Coast Citrus by Propello Life

Ask about any prescription or over-the-counter medication and we check it for interactions with Non-GMO Pre-Workout West Coast Citrus by Propello Life — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Non-GMO Pre-Workout West Coast Citrus by Propello Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This pre-workout has 5 active ingredients. Creatine monohydrate helps your muscles produce energy during exercise.

Beta-alanine works similarly, supporting athletic output. Betaine anhydrous aids muscle function and strength.

L-citrulline malate converts to a compound that boosts blood flow to working muscles. Natural caffeine is a stimulant that sharpens mental focus and can enhance athletic performance.

The product also contains inactive ingredients like natural citrus flavor, malic acid, tapioca maltodextrin, stevia leaf extract, and silicon dioxide — these are fillers and binders that make up the powder.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Athletic performance and high-intensity exercise.
  • We looked for evidence on: Athletic performance, Physical performance, Exercise-induced muscle breakdown, Exercise-induced muscle soreness, Muscle strength, Endurance — and 2 related terms.
  • The strongest evidence on file: Caffeine is rated "Likely Effective" for Athletic performance (Natural Medicines).
  • Also on file: Creatine is rated "Possibly Effective" for Athletic performance, Muscle strength.
  • Also on file: Beta-alanine is rated "Possibly Effective" for Athletic performance, Physical performance.

Creatine monohydrate is possibly effective for building muscle strength, improving athletic performance, and countering age-related muscle loss (sarcopenia). Beta-alanine is possibly effective for athletic and physical performance.

Caffeine is likely effective for mental alertness and athletic performance. L-citrulline malate is possibly effective for athletic performance.

Betaine anhydrous shows good evidence for a rare genetic disorder (homocystinuria) and possibly helps lower a compound called homocysteine, but evidence for most other uses — including general athletic benefit — isn't established in our data. Several of these ingredients have been studied for other conditions, but the evidence isn't strong enough to call them effective for those purposes.

The evidence, ingredient by ingredient Creatine Beta-alanine Betaine Anhydrous L-citrulline Caffeine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Overall, these five ingredients are generally well tolerated in healthy adults. The most common side effects are mild: creatine may cause water retention, muscle cramps, or diarrhea; beta-alanine commonly causes a harmless tingling or flushing sensation that lasts about an hour and subsides with continued use; L-citrulline may cause stomach discomfort or heartburn; and caffeine can cause jitteriness, anxiety, insomnia, and headache in sensitive people.

Betaine may cause body odor, nausea, or diarrhea. Serious side effects are rare but have been reported — creatine carries rare reports of kidney problems and muscle breakdown, and caffeine very rarely may cause stroke.

Pregnancy and breastfeeding: Safety data during pregnancy is insufficient or advises against use for creatine, beta-alanine, and L-citrulline — talk with your doctor before using if you're pregnant or planning to become pregnant. Betaine has not been studied enough in pregnancy; breastfeeding safety is also unclear — discuss with your pharmacist or doctor.

Caffeine passes into breast milk in small amounts; moderate intake is usually considered acceptable, but high amounts may affect your baby.

Side effects, ingredient by ingredient Creatine Beta-alanine Betaine Anhydrous L-citrulline Caffeine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 2 of the 5 matched ingredients can interact with medications — Caffeine, L-citrulline.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 756 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check if you use ephedrine with your medications — this is the most serious concern. Also check whether you take any blood pressure-lowering drugs (antihypertensives), erectile dysfunction medications (phosphodiesterase-5 inhibitors), sleep aids (barbiturates like pentobarbital or phenobarbital), the heart medication dipyridamole, the antiseizure drug carbamazepine, the antipsychotic clozapine, the heartburn medication cimetidine, or quinolone antibiotics.

Caffeine in this product can interact with all of these.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This pre-workout is designed for people looking to boost athletic performance and muscle strength during training. If you take any blood pressure medications, heart drugs, sleep aids, antibiotics, antipsychotics, or anything with ephedrine, you need to check your specific medications before starting — the caffeine and L-citrulline can interact with them.

Talk to your pharmacist before you buy, especially if you're pregnant, breastfeeding, have kidney issues, or take any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Non-GMO Pre-Workout West Coast Citrus, straight from the product label.

Brand Propello Life
Barcode (UPC) 859619006312
Net contents 450 Gram(s)
Market status On market
Date entered into DSLD Jan 25, 2017
DSLD ID 69559
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Non-GMO Pre-Workout West Coast Citrus by Propello Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
15 Gram(s)
Maximum serving Sizes:
15 Gram(s)
Servings per container
30
UPC/BARCODE
859619006312
IngredientAmount% DV
Calories36 Calorie(s)--
Creatine Monohydrate5 Gram(s)--
Beta-Alanine1.6 Gram(s)--
Betaine Anhydrous2.5 Gram(s)--
L-Citrulline Malate3 Gram(s)--
natural Caffeine100 mg--

Other ingredients: natural Citrus flavor, Malic Acid, Tapioca Maltodextrin, Stevia leaf extract, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

No artificial colors or sweeteners

Non-GMO

General Statements

Made in Canada

Live for it

We hand selected each ingredient to give us more focus, energy, power, endurance, and better blood flow, resulting in a better workout and lean muscle growth. As fathers, this product is sometimes the only thing that gets us through our full days!

Live for it. Duke & Todd

Liveforit

Precautions

Recycle or reuse this canister.

Allergen Warning: Made in a facility that also produces milk, egg, soy, tree nuts, peanuts, fish/crustaceans/shellfish oils and wheat products.

Warning: If you are pregnant, breastfeeding, under the age of 18 or taking medication, consult your physician before using this product.

Warning: If you are pregnant, breastfeeding, under the age of 18 or taking medication, consult your physician before using this product.

Seals/Symbols

GMP Certified Good manufacturing practices

Formula

5 grams of creatine monohydrate 3 grams of citruline malate 2:1 1.6 grams of beta alanine 100 mg of natural caffeine 2.5 grams of betaine

FDA Statement of Identity

Dietary Supplement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Suggested/Recommended/Usage/Directions

Our favorite use for Pre-Workout is mixed with water as a pre-workout boost or as a morning pick-me-up.

Recommended Use: For a delicious drink, mix one scoop of Pre-Workout with 8-10 ounces of cold water. Shake well and continue to shake while consuming, as the creatine may settle at the bottom.

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Non-GMO Pre-Workout West Coast Citrus by Propello Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Non-GMO Pre-Workout West Coast Citrus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Non-GMO Pre-Workout West Coast Citrus by Propello Life

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size15 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Creatine Monohydrate

No known
interactions
5 Gram(s) per serving

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...

Creatine Monohydrate monograph & interactions

Beta-Alanine

No known
interactions
1.6 Gram(s) per serving

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-int...

Beta-Alanine monograph & interactions

Betaine Anhydrous

No known
interactions
2.5 Gram(s) per serving

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and a...

Betaine Anhydrous monograph & interactions

L-Citrulline Malate

Interacts with
178 drugs
3 Gram(s) per serving

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...

L-Citrulline Malate monograph & interactions

Natural Caffeine

Interacts with
655 drugs
100 mg per serving Form: Robusta Coffee

Caffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredn...

Natural Caffeine monograph & interactions

Other (inactive) ingredients: Natural Citrus flavor, Malic Acid, Tapioca Maltodextrin, Stevia leaf extract, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Non-GMO Pre-Workout West Coast Citrus by Propello Life Drug Interactions

Want to check YOUR meds against Non-GMO Pre-Workout West Coast Citrus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
756Drugs
8 Major 586 Moderate 162 Minor

Ingredients driving the most interactions

natural Caffeine 655
L-Citrulline Malate 178

Individual Drug Interactions

The ingredients in Non-GMO Pre-Workout West Coast Citrus interact with 756 drugs. Click any drug to see the details.

2 of the 5 ingredients in Non-GMO Pre-Workout West Coast Citrus interact with drugs. Each result below shows which ingredient is responsible. natural Caffeine L-Citrulline Malate

Each ingredient & the kinds of drugs it affects

For each ingredient in Non-GMO Pre-Workout West Coast Citrus with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

natural Caffeine41 drug types · 655 drugs

Ephedrine

Theoretically, concomitant use might increase the risk for stimulant adverse effects.
Use of ephedrine with caffeine can increase the risk of stimulatory adverse effects. There is evidence that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction, stroke, seizures, and death.

Likelihood Probable Evidence D
Adenosine (Adenocard)

Theoretically, caffeine might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Some evidence shows that caffeine is a competitive inhibitor of adenosine and can reduce the vasodilatory effects of adenosine in humans. However, other research shows that caffeine does not seem to affect supplemental adenosine because high interstitial levels of adenosine overcome the antagonistic effects of caffeine. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. However, methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Possible Evidence B
Anticoagulant/Antiplatelet Drugs

Theoretically, caffeine may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Caffeine is reported to have antiplatelet activity. Theoretically, it might increase the risk of bleeding when used concomitantly with these agents; however, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Beta-Adrenergic Agonists

Theoretically, large amounts of caffeine might increase the cardiac inotropic effects of beta-agonists.

Likelihood Probable Evidence D
Carbamazepine (Tegretol)

Theoretically, caffeine might reduce the effects of carbamazepine and increase the risk for convulsions.
Animal research suggests that taking caffeine can lower the anticonvulsant effects of carbamazepine and can induce seizures when taken in doses above 400 mg/kg. Human research has shown that taking caffeine 300 mg in three divided doses along with carbamazepine 200 mg reduces the bioavailability of carbamazepine by 32% and prolongs the plasma half-life of carbamazepine 2-fold in healthy individuals.

Likelihood Possible Evidence D
Cimetidine (Tagamet)

Theoretically, cimetidine might increase the levels and adverse effects of caffeine.
Cimetidine decreases the rate of caffeine clearance by 31% to 42%.

Likelihood Likely Evidence B
Clozapine (Clozaril)

Caffeine might increase the levels and adverse effects of clozapine and acutely exacerbate psychotic symptoms.
Caffeine might increase the effects and toxicity of clozapine. Caffeine doses of 400-1000 mg per day inhibit clozapine metabolism. Clozapine is metabolized by cytochrome P450 1A2 (CYP1A2). Although researchers speculate that caffeine might inhibit CYP1A2, there is no reliable evidence that caffeine affects CYP1A2. There is also speculation that genetic factors might make some patients more sensitive to an interaction between clozapine and caffeine. In one case report, severe, life-threatening clozapine toxicity and multiorgan system failure occurred in a patient with schizophrenia stabilized on clozapine who consumed caffeine 600 mg daily.

Likelihood Possible Evidence B
Dipyridamole (Persantine)

Theoretically, caffeine might decrease the vasodilatory effects of dipyridamole and interfere with its use prior to stress testing.
Caffeine inhibits dipyridamole-induced vasodilation. It is recommended that methylxanthines and methylxanthine-containing products be stopped 24 hours prior to pharmacological stress tests. Methylxanthines appear more likely to interfere with dipyridamole (Persantine) than adenosine-induced stress testing.

Likelihood Probable Evidence B
Disulfiram (Antabuse)

Theoretically, disulfiram use might increase the levels and adverse effects of caffeine.
Disulfiram decreases the rate of caffeine clearance.

Likelihood Probable Evidence B
Diuretic Drugs

Theoretically, using caffeine with diuretic drugs might increase the risk of hypokalemia.
Caffeine, especially in excessive amounts, can reduce potassium levels due to stimulation of the sodium-potassium pump. Diuretics can also cause lower potassium levels.

Likelihood Possible Evidence D
Estrogens

Theoretically, estrogens might increase the levels and adverse effects of caffeine.
Estrogen inhibits caffeine metabolism.

Likelihood Probable Evidence B
Ethosuximide (Zarontin)

Theoretically, caffeine might reduce the effects of ethosuximide and increase the risk for convulsions.
Animal research suggests that caffeine 92.4 mg/kg can decrease the anticonvulsant activity of ethosuximide. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Felbamate (Felbatol)

Theoretically, caffeine might reduce the effects of felbamate and increase the risk for convulsions.
Animal research suggests that a high dose of caffeine 161.7 mg/kg can decreases the anticonvulsant activity of felbamate. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Flutamide (Eulexin)

Theoretically, caffeine might increase the levels and adverse effects of flutamide.
In vitro evidence suggests that caffeine can inhibit the metabolism of flutamide. However, this effect has not been reported in humans.

Likelihood Probable Evidence D
Fluvoxamine (Luvox)

Theoretically, fluvoxamine might increase the levels and adverse effects of caffeine.
Fluvoxamine reduces caffeine metabolism.

Likelihood Probable Evidence D
Lithium

Abrupt caffeine withdrawal might increase the levels and adverse effects of lithium.
Caffeine has diuretic activity. When abruptly discontinued, caffeine may alter the clearance of lithium. There are two case reports of lithium tremor that worsened upon abrupt coffee withdrawal and 6 case reports of elevated serum lithium levels after reducing or eliminating caffeine intake. In one case, a male with schizoaffective disorder stabilized on lithium had an elevated lithium level after reducing his caffeine intake by 87%. At a later date, he increased his caffeine intake by 6-fold, resulting in a subtherapeutic lithium level and a recurrence of psychiatric symptoms.

Likelihood Probable Evidence D
Monoamine Oxidase Inhibitors (Maois)

Theoretically, concomitant use might increase the risk of a hypertensive crisis.
Caffeine has been shown to inhibit monoamine oxidase (MAO) A and B in laboratory studies. Concomitant intake of large amounts of caffeine with MAOIs might precipitate a hypertensive crisis. In a case report, a patient that consumed 10-12 cups of caffeinated coffee and took the MAOI tranylcypromine presented with severe hypertension. Hypertension was resolved after the patient switched to drinking decaffeinated coffee.

Likelihood Possible Evidence D
Nicotine

Theoretically, concomitant use might increase the risk of hypertension.
Concomitant use of caffeine and nicotine has been shown to have additive cardiovascular effects, including increased heart rate and blood pressure. Blood pressure was increased by 10.8/12.4 mmHg when the agents were used concomitantly.

Likelihood Probable Evidence B
Pentobarbital (Nembutal)

Theoretically, caffeine might decrease the effects of pentobarbital.
Caffeine might negate the hypnotic effects of pentobarbital.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

Theoretically, caffeine might reduce the effects of phenobarbital and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenobarbital. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Phenylpropanolamine

Theoretically, phenylpropanolamine might increase the risk of hypertension, as well as the levels and adverse effects of caffeine.
Concomitant use of phenylpropanolamine and caffeine might cause an additive increase in blood pressure. Phenylpropanolamine also seems to increase caffeine serum levels.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Theoretically, caffeine might reduce the effects of phenytoin and increase the risk for convulsions.
Animal research suggests that caffeine can decrease the anticonvulsant activity of phenytoin. The effect does not seem to be related to the seizure threshold-lowering effects of caffeine. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Pioglitazone (Actos)

Theoretically, caffeine might increase the levels and clinical effects of pioglitazone.
Animal research suggests that caffeine can modestly increase the maximum concentration, area under the curve, and half-life of pioglitazone, and also reduce its clearance. This increased the antidiabetic effects of pioglitazone. However, the exact mechanism of this interaction is unclear.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, quinolone antibiotics might increase the levels and adverse effects of caffeine.
Quinolones (also called fluoroquinolones) can decrease caffeine clearance by inhibiting cytochrome P450 1A2 (CYP1A2) enzyme.

Likelihood Probable Evidence B
Riluzole (Rilutek)

Theoretically, concomitant use might increase the levels and adverse effects of both caffeine and riluzole.
Caffeine and riluzole are both metabolized by cytochrome P450 1A2 (CYP1A2), and concomitant use might reduce the metabolism of one or both agents.

Likelihood Possible Evidence D
natural Caffeine full monograph & all 41 interactions

L-Citrulline Malate2 drug types · 178 drugs

Antihypertensive Drugs

Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.

Likelihood Possible Evidence B
Phosphodiesterase-5 Inhibitors

Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.

Likelihood Possible Evidence D
L-Citrulline Malate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Non-GMO Pre-Workout West Coast Citrus, from the product label.

Propello Life

See all Propello Life products
Name
Propello Life
Street Address
PO Box 404
City
Dublin
State
OH
ZipCode
43017
Web Address
[email protected]
Pharmacist Counseling Corner

Non-GMO Pre-Workout West Coast Citrus by Propello Life: Common Questions

Does Non-GMO Pre-Workout West Coast Citrus by Propello Life interact with any medications?
Yes. Based on its ingredients, Non-GMO Pre-Workout West Coast Citrus has a known interaction with 756 medications, including 8 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Non-GMO Pre-Workout West Coast Citrus contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is creatine monohydrate and what does it do?
Creatine helps your muscle cells make energy during heavy exercise. It's possibly effective for building strength, improving athletic performance, and slowing age-related muscle loss. The evidence is strongest for athletic training in healthy adults.
I keep hearing about the tingling from beta-alanine — is that dangerous?
No, it's harmless. That tingling and flushing sensation starts on your scalp within 20 minutes and lasts about an hour. It's dose-dependent — lower doses cause less tingling — and goes away with regular use. It's just how your body reacts to the ingredient.
Can I take this while I'm pregnant?
The safety data is not established enough for most of these ingredients during pregnancy. Creatine, beta-alanine, and L-citrulline all advise against use. Betaine and caffeine haven't been studied thoroughly either. Talk with your doctor or pharmacist before using any of them if you're pregnant or planning to become pregnant.
How much caffeine is in this?
The product facts don't specify the exact amount of natural caffeine per serving. You'll want to check the nutrition label on the package or contact the manufacturer to know your total caffeine intake, especially if you're also drinking coffee, tea, or energy drinks.
Is this safe if I have kidney problems?
Creatine carries a caution for people with kidney issues — check with your healthcare provider before using this product if you have any kidney concerns or reduced kidney function. The other ingredients don't specifically call out kidney concerns, but it's best to get personalized advice from your doctor or pharmacist.
Do any of these ingredients actually work for athletic performance?
Creatine and caffeine have the strongest evidence — both are likely or possibly effective for athletic performance. Beta-alanine and L-citrulline are possibly effective as well. Betaine's evidence for athletic benefit isn't established in our data. Real results depend on your training, diet, and how your body responds.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Non-GMO Pre-Workout West Coast Citrus is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Non-GMO Pre-Workout West Coast Citrus label
Go deeper

The Full Monographs Behind Non-GMO Pre-Workout West Coast Citrus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Creatine

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...

Read the full Creatine monograph → Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph → Herb & supplement monograph

Betaine Anhydrous

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and as a prescription medicine for a rare gen...

Read the full Betaine Anhydrous monograph → Herb & supplement monograph

L-citrulline

Interacts with 178 drugs

L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...

Read the full L-citrulline monograph → Herb & supplement monograph

Caffeine

Interacts with 655 drugs

Caffeine is a natural stimulant found in coffee, tea, and many other plants and products. In moderate amounts it can boost alertness and reduce tiredness for most healthy adults, but too muc...

Read the full Caffeine monograph →
Sources

Sources & How We Checked

Non-GMO Pre-Workout West Coast Citrus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 354 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Creatine 86 references
  1. Koshy KM, Griswold E, Schneeberger EE. Interstitial nephritis in a patient taking creatine. N Engl J Med 1999;340:814-5. PubMed
  2. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
  3. Greenhaff P. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;352:233-4. PubMed
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