Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Omega 3, 6 & 9 Ingredients & Drug Interactions

by Omojo

Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Major
The interaction bottom line Most serious interaction: Major

Omega 3, 6 & 9 is a dietary supplement by Omojo with 2 active ingredients. Its ingredients are commonly taken for eye and vision health, skin health and acne, immune support.Based on those ingredients, 387 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin A. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Omega 3, 6 & 9 by Omojo

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This softgel contains two active ingredients. Vitamin A is a fat-soluble vitamin your body stores in fat tissue and uses for vision, immune function, and skin health.

Shark liver oil is derived from shark liver and contains compounds like squalene, though evidence for its health benefits is not yet well established. The softgels also contain gelatin and glycerin as inactive ingredients to hold the formula together and improve absorption.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: heart, cholesterol, immune and skin health.
  • We looked for evidence on: Acne, Aging skin, Atopic dermatitis (eczema), Atopic disease, Common cold, Influenza — and 4 related terms.
  • The strongest evidence on file: Vitamin A is rated "Possibly Effective" for Aging skin (Natural Medicines).
  • Also on file: Vitamin A is rated "Possibly Ineffective" for Atopic disease, Melanoma.
  • Also on file: Shark Liver Oil is rated "Insufficient Reliable Evidence To Rate" for Cancer, Common cold, Influenza, Wound healing.

Vitamin A is effective for treating vitamin A deficiency and shows possibly effective evidence for oral leukoplakia, aging skin, measles, ulcerative colitis, and bronchopulmonary dysplasia. Shark liver oil, however, has insufficient evidence to rate it for any of the conditions studied—cancer, common cold, influenza, chemotherapy-related effects, and radiation-induced nausea have not been reliably established.

The evidence, ingredient by ingredient Vitamin A Shark Liver Oil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin A is generally well tolerated at recommended doses, but here's the catch: it's fat-soluble, so it builds up in your body over time and can become toxic in high doses. Very high doses can cause liver damage, headaches, blurred vision, skin problems, and in rare cases, serious neurological effects.

Shark liver oil is generally tolerated short-term, but human safety data is limited and product quality varies; a case of severe liver inflammation has been reported, and high doses may raise cholesterol and increase the risk of a rare type of pneumonia from aspiration. For pregnancy and lactation: vitamin A safety data are mixed—normal dietary amounts and recommended supplement doses are appropriate, but high-dose vitamin A (especially as retinol) is possibly unsafe in pregnancy because it may cause birth defects.

There isn't enough safety data for shark liver oil in pregnancy or while breastfeeding, so those are best avoided during those times. Talk with your OB or pharmacist if you're pregnant or nursing.

Side effects, ingredient by ingredient Vitamin A Shark Liver Oil

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Vitamin A.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 388 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check if you use retinoid acne or anti-aging medications (tretinoin, isotretinoin)—that's a Major concern. Also flag blood thinners like warfarin, tetracycline antibiotics, and any medications that can affect your liver.

These Moderate interactions mean your dose and timing matter.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is reasonable for someone looking to supplement vitamin A at moderate doses, but not if you take retinoid medications, blood thinners, or tetracycline antibiotics without checking first. The shark liver oil component has unproven benefits and limited safety data.

If you're pregnant, nursing, or have liver disease, ask your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Omega 3, 6 & 9, straight from the product label.

Brand Omojo
Barcode (UPC) 852073003507
Net contents 90 Softgel(s); 500 mg
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 22104
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Omega 3, 6 & 9 by Omojo, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
90
UPC/BARCODE
852073003507
IngredientAmount% DV
Vitamin A900 IU18%
Shark Liver Oil500 mg--

Other ingredients: Gelatin, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

omega 3, 6 & 9 shark oils softgels Omega GLA, CLA and antioxidants DMAE support heart and cholesterol health. This powerful combination of nutrients provides a broad spectrum of overall health benefits including immune and skin health.

ESSENTIAL IN SUPPORTING HEART HEALTH, BLOOD VESSELS, BRAIN, SKIN AND EYES

Shark Oil FORMULA support heart health + body's natural anti-inflammatory response

30 DAY SUPPLY 100% traceable, all natural ingredients

CELLULAR HEALTH INSIDE

Please recycle this package

Not a significant source of Vitamin C, Calcium or Iron

Suggested/Recommended/Usage/Directions

Suggested use: Take one softgel three times daily before a meal, or as directed by a health care professional.

Precautions

- Keep out of reach of children

- Discontinue use if you feel any discomfort

- Tamper evident; purchase only if seal is intact

If you are pregnant or nursing, or have a heart or circulatory condition, or have had recent surgery, consult a health care professional before using this product.

Storage

- Store in a cool, dry place

General

SKU: 101

FDA Statement of Identity

ALL NATURAL DIETARY SUPPLEMENT

Seals/Symbols

OMOJO(TM)

{US Flag}

HACCP

GMP

MARINE SUSTAINABLE

Formulation

Contains No Additives or Fillers.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, diagnose, cure or prevent any disease.

See for yourself

Omega 3, 6 & 9 by Omojo label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Omega 3, 6 & 9 by Omojo

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin A

Interacts with
387 drugs
900 IU per serving

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplemen...

Vitamin A monograph & interactions

Shark Liver Oil

No known
interactions
500 mg per serving

Shark liver oil is taken from the livers of deep-sea sharks and is rich in compounds called alkylglycerols and squalene. People use it for immune supp...

Shark Liver Oil monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Omega 3, 6 & 9 by Omojo Drug Interactions

Want to check YOUR meds against Omega 3, 6 & 9?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
387Drugs
9 Major 378 Moderate

Ingredients driving the most interactions

Vitamin A 387

Each ingredient & the kinds of drugs it affects

For each ingredient in Omega 3, 6 & 9 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin A4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Omega 3, 6 & 9, from the product label.

Omojo

See all Omojo products
Name
OMOJO HEALTH USA
Street Address
333 North Hill Blvd
City
Burlington
State
WA
ZipCode
98233
Web Address
WWW.OMOJOHEALTHUSA.COM
Pharmacist Counseling Corner

Omega 3, 6 & 9 by Omojo: Common Questions

Does Omega 3, 6 & 9 by Omojo interact with any medications?
Yes. Based on its ingredients, Omega 3, 6 & 9 has a known interaction with 387 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Omega 3, 6 & 9 contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is vitamin A in this product safe for pregnancy?
Normal dietary and recommended supplement amounts of vitamin A are appropriate during pregnancy, but high-dose vitamin A (especially as retinol) is possibly unsafe because it may cause birth defects. This product's dose matters—check the label and talk with your OB or pharmacist to make sure it's right for you.
What does shark liver oil actually do?
We don't have established evidence that shark liver oil works for the conditions it's been studied for—cancer, colds, flu, and others all have insufficient reliable evidence. It's generally tolerated short-term, but we don't have a lot of human safety data, and product quality varies between brands.
Can I take this if I'm on warfarin?
Vitamin A at high doses may increase your bleeding risk with warfarin, though the data are theoretical. This is a Moderate interaction, so don't skip it—check the exact dose in this product and run it by your pharmacist or doctor before starting.
What are the side effects of vitamin A?
At recommended doses below the safe upper limit, vitamin A is generally well tolerated. At high doses, it can cause fatigue, dry and itchy skin, hair loss, headaches, and blurred vision. In very high doses, it can damage the liver and cause serious neurological problems—which is why it's important not to exceed recommended amounts, especially over time.
Does this product have any fillers?
Yes—the softgels contain gelatin and glycerin as inactive ingredients to hold the formula and help your body absorb it.
Is it safe to take this if I'm on tetracycline antibiotics?
High doses of vitamin A combined with tetracycline antibiotics (like doxycycline) can theoretically increase the risk of raised pressure inside your skull—a Moderate interaction. Check the vitamin A dose in this product and confirm with your pharmacist that it's safe alongside your antibiotic.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Omega 3, 6 & 9 is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Omega 3, 6 & 9 label
Sources

Sources & How We Checked

Omega 3, 6 & 9's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 37 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin A 31 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Griffiths JK. The vitamin A paradox. J Pediatr 2000;137:604-7.. PubMed
  3. Hardman JG, Limbird LL, Molinoff PB, eds. Goodman and Gillman's The Pharmacological Basis of Therapeutics, 9th ed. New York, NY: McGraw-Hill, 1996.
  4. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  5. FDA Talk Paper. Vitamin A and birth defects (T95-56). Food and Drug Administration, U.S. Department of Health and Human Services, Rockville, MD. October 6, 1995.
  6. Russell RM. The vitamin A spectrum: from deficiency to toxicity. Am J Clin Nutr 2000;71:878-84. PubMed
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Feskanich D, Singh V, Willett WC, Colditz GA. Vitamin A intake and hip fractures among postmenopausal women. JAMA 2002;287:47-54. PubMed
  9. Melhus H, Michaelsson K, Kindmark A, et al. Excessive dietary intake of vitamin A is associated with reduced bone mineral density and increased risk for hip fracture. Ann Intern Med 1998;129:770-8. PubMed
  10. Michaelsson K, Lithell H, Vessby B, Melhus H. Serum retinol levels and the risk of fracture. N Engl J Med 2003;348:287-94.. PubMed
  11. Botterweck AA, van den Brandt PA, Goldbohm RA. Vitamins, carotenoids, dietary fiber, and the risk of gastric carcinoma: results from a prospective study after 6.3 years of follow-up. Cancer 2000;88:737-48.. DOI
  12. Meyskens FL Jr, Graham V, Chvapil M, et al. A phase I trial of beta-all-trans-retinoic acid delivered via a collagen sponge and a cervical cap for mild or moderate intraepithelial cervical neoplasia. J Natl Cancer Inst 1983;71:921-5..
  13. Hathcock JN, Hattan DG, Jenkins MY, et al. Evaluation of vitamin A toxicity. Am J Clin Nutr 1990;52:183-202.. PubMed
  14. Walters BN, Gubbay SS. Tetracycline and benign intracranial hypertension: report of five cases. Br Med J 1981;282:19-20.. PubMed
  15. Pearson MG, Littlewood SM, Bowden AN. Tetracycline and benign intracranial hypertension (letter). Br Med J 1981;282:568-9.. PubMed
  16. Azais-Braesco V, Pascal G. Vitamin A in pregnancy: requirements and safety limits. Am J Clin Nutr 2000;71:1325S-33S. PubMed
  17. Smedts HP, de Vries JH, Rakhshandehroo M, et al. High maternal vitamin E intake by diet or supplements is associated with congenital heart defects in the offspring. BJOG 2009;116:416-23. PubMed
  18. Grotto, I., Mimouni, M., Gdalevich, M., and Mimouni, D. Vitamin A supplementation and childhood morbidity from diarrhea and respiratory infections: a meta-analysis. J Pediatr 2003;142(3):297-304. PubMed
  19. Mahalanabis, D., Lahiri, M., Paul, D., Gupta, S., Gupta, A., Wahed, M. A., and Khaled, M. A. Randomized, double-blind, placebo-controlled clinical trial of the efficacy of treatment with zinc or vitamin A in infants and young children with severe acute l
  20. Long, K. Z., Montoya, Y., Hertzmark, E., Santos, J. I., and Rosado, J. L. A double-blind, randomized, clinical trial of the effect of vitamin A and zinc supplementation on diarrheal disease and respiratory tract infections in children in Mexico City, Mex
  21. Fritz, H., Kennedy, D., Fergusson, D., Fernandes, R., Doucette, S., Cooley, K., Seely, A., Sagar, S., Wong, R., and Seely, D. Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis. PLoS.One. 2011;6(6):e21107. PubMed
  22. Mayo-Wilson, E., Imdad, A., Herzer, K., Yakoob, M. Y., and Bhutta, Z. A. Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis. BMJ 2011;343:d5094. PubMed
  23. Mazumder S, Taneja S, Bhatia K, Yoshida S, Kaur J, Dube B, Toteja GS, Bahl R, Fontaine O, Martines J, Bhandari N; Neovita India Study Group. Efficacy of early neonatal supplementation with vitamin A to reduce mortality in infancy in Haryana, India (Neovit
  24. Baineni R, Gulati R, Delhi CK. Vitamin A toxicity presenting as bone pain. Arch Dis Child. 2017;102(6):556-8. PubMed
  25. Darlow BA, Graham PJ, Rojas-Reyes MX. Vitamin A supplementation to prevent mortality and short- and long-term morbidity in very low birth weight infants. Cochrane Database Syst Rev. 2016;(8):CD000501. PubMed
  26. Haider BA, Sharma R, Bhutta ZA. Neonatal vitamin A supplementation for the prevention of mortality and morbidity in term neonates in low and middle income countries. Cochrane Database Syst Rev. 2017;2:CD006980. PubMed
  27. Mohammad YM, Raslan IR, Al-Hussain FA. Idiopathic Intracranial Hypertension Induced by Topical Application of Vitamin A. J Neuroophthalmol. 2016;36(4):412-3. PubMed
  28. Masnadi Shirazi K, Nikniaz Z, Masnadi Shirazi A, Rohani M. Vitamin A supplementation decreases disease activity index in patients with ulcerative colitis: A randomized controlled clinical trial. Complement Ther Med. 2018 Dec;41:215-219. PubMed
  29. Ding Y, Hu P, Yang Y, et al. Impact of maternal daily oral low-dose vitamin A supplementation on the mother-infant pair: a randomised placebo-controlled trial in China. Nutrients 2021;13(7):2370. PubMed
  30. Knapik JJ, Hoedebecke SS. Vitamin A and bone fractures: systematic review and meta-analysis. J Spec Oper Med 2021;21(2):100-7. PubMed
  31. Imdad A, Mayo-Wilson E, Haykal MR, et al. Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age. Cochrane Database Syst Rev 2022;3(3):CD008524. PubMed

See these in context on the Vitamin A monograph →

Shark Liver Oil 6 references
  1. Lee JY, Lee KS, Kim TS, et al. Squalene-induced extrinsic lipoid pneumonia: serial radiologic findings in nine patients. J Comput Assist Tomogr 1999;23:730-5. PubMed
  2. Lee JS, Im JG, Song KS, et al. Exogenous lipoid pneumonia: high-resolution CT findings. Eur Radiol 1999;9:287-91. PubMed
  3. Asnis DS, Saltzman HP, Melchert A. Shark oil pneumonia. An overlooked entity. Chest 1993;103:976-7.
  4. Deniau AL, Mosset P, Pédrono F, Mitre R, Le Bot D, Legrand AB. Multiple beneficial health effects of natural alkylglycerols from shark liver oil. Mar Drugs. 2010 Jul 19;8(7):2175-84. PubMed
  5. Kilincalp S, Deveci M, Basar O, Ekiz F, Coban S, Yuksel O. Shark liver oil: hidden dangers. Ann Hepatol. 2012 Sep-Oct;11(5):728-30. DOI
  6. Hamadate N, Matsumoto Y, Seto K, Yamamoto T, Yamaguchi H, Nakagawa T, Yamamoto E, Fukagawa M, Yazawa K. Vascular effects and safety of supplementation with shark liver oil in middle-aged and elderly males. Exp Ther Med. 2015 Aug;10(2):641-646. Epub 2015 J PubMed

See these in context on the Shark Liver Oil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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