Omega 3 Krill Oil Ingredients & Drug Interactions
by Crystal Star
What is this page for?
First and foremost: checking Omega 3 Krill Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Omega 3 Krill Oil is a dietary supplement by Crystal Star with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 848 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin, SuperbaBoost Krill Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Omega 3 Krill Oil by Crystal Star
Ask about any prescription or over-the-counter medication and we check it for interactions with Omega 3 Krill Oil by Crystal Star — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Omega 3 Krill Oil by Crystal Star
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Crystal Star Omega 3 Krill Oil is a softgel containing 7 active ingredients centered on Antarctic krill extract. The main components are eicosapentaenoic acid and docosahexaenoic acid — two omega-3 fatty acids — along with phospholipids, polyunsaturated fat, and total omega-3 fatty acids from the krill itself.
It also includes astaxanthin, a natural red pigment from krill with antioxidant properties, and choline, a nutrient important for cell and brain function. The softgel capsule also contains gelatin, sorbitol, glycerin, and purified water as inactive ingredients.
Does it work?
Not established
The evidence supporting astaxanthin for age-related cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome is insufficient to rate it reliably. Choline is rated possibly ineffective for athletic performance, and evidence for its use in bronchitis, cognitive decline, liver fat buildup with IV nutrition, hay fever, and Alzheimer disease is also insufficient.
We hold no effectiveness data for the omega-3 fatty acids in this product.
How safe is it?
Well-documented data
Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects from astaxanthin are abdominal pain, diarrhea, and red-colored stools; at higher doses, severe stomach pain has been reported.
Choline is well tolerated at food amounts, but high-dose supplements can cause fishy body odor, and doses above 9 grams daily have caused diarrhea, nausea, salivation, and vomiting. Because there isn't enough safety data for astaxanthin during pregnancy and breastfeeding, it's best to avoid it at those times.
Choline is likely safe in pregnancy and is important then, but use only doses advised by your doctor; breastfeeding needs are higher, so use supplements only under professional guidance.
Meds to double-check
Moderate interaction found
If you take any medication metabolized by CYP3A4 or CYP2B6 enzymes — ask your pharmacist if you're unsure — or if you use atropine, check with your doctor or pharmacist before adding this product. We couldn't fully check the krill oil fatty acids themselves, so there may be additional interactions we haven't documented.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This krill oil supplement may appeal to you if you're looking for omega-3s and antioxidant support, but be careful if you take medications processed by your liver — astaxanthin may theoretically affect how those drugs work — or if you use atropine. The evidence for astaxanthin's effectiveness for most claimed uses isn't established.
Talk with your doctor or pharmacist before starting, especially if you're pregnant, breastfeeding, or taking prescription medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Omega 3 Krill Oil, straight from the product label.
| Brand | Crystal Star |
|---|---|
| Barcode (UPC) | 747889000041 |
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2021 |
| DSLD ID | 243916 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Girls: (All), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Omega 3 Krill Oil by Crystal Star, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 Calorie(s) | -- |
| Eicosapentaenoic Acid | 300 mg | -- |
| Docosahexaenoic Acid | 140 mg | -- |
| Phospholipids | 1120 mg | -- |
| Cholesterol | 40 mg | 13% |
| Total Fat | 2 Gram(s) | 2% |
| Polyunsaturated Fat | 0.5 Gram(s) | -- |
| Astaxanthin | 170 mcg | -- |
| Total Omega-3 Fatty Acids | 540 mg | -- |
| Saturated Fat | 0.5 Gram(s) | 2% |
| Choline | 140 mg | 9% |
| SuperbaBoost Krill Oil | 2000 mg | -- |
Other ingredients: Gelatin, Sorbitol, Glycerin, purified Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Crystal Star ESTD 1978
Formula
More concentrated EPA, DHA & Phospholipids 1000 mg SUPERBABoost
Omega 3 phospholipids choline & astaxanthin
Formulation
Sustainably fished
Non-GMO product
3rd party tested
Promotes heart, brain, eye & liver health Pure antarctic krill no fishy aftertaste
Does not contain gluten.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use Take 2 softgels daily.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Brand IP Statement(s)
Copyright 2020 Healthy Healing Enterprises LLC.
SUPERBABoost is a registered trademark of Aker BioMarine Antarctic AS.
Precautions
Contains: Shellfish (krill)
Warning: Do not use if tamper proof seal is damaged or missing.
Do not use if pregnant or nursing. Consult a health care professional prior to use if you have any pre-existing medial conditions or are taking any prescription medications.
Keep out of reach of children.
Seals/Symbols
U.S. F.D.A. REG. FACILITY
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Omega 3 Krill Oil by Crystal Star label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Omega 3 Krill Oil by Crystal Star
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Phospholipids
Astaxanthin
Interacts with671 drugs
Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...
Astaxanthin monograph & interactionsSuperbaBoost Krill Oil
Interacts with208 drugs
Krill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglyce...
SuperbaBoost Krill Oil monograph & interactions- › Eicosapentaenoic Acid
- › Docosahexaenoic Acid
- › Total Omega-3 Fatty Acids
- › Choline
Other (inactive) ingredients: Gelatin, Sorbitol, Glycerin, Purified Water. These complete the product’s ingredient list but are not active constituents.
Omega 3 Krill Oil by Crystal Star Drug Interactions
HelloPharmacist Interaction Report
Crystal Star Omega 3 Krill Oil contains several ingredients we haven't fully checked for interactions — eicosapentaenoic acid, docosahexaenoic acid, phospholipids, polyunsaturated fat, and total omega-3 fatty acids — so we can't rule out effects with certain medications.
The two ingredients we did check are astaxanthin and choline. Astaxanthin may theoretically slow how your body clears drugs metabolized by your liver's CYP3A4 and CYP2B6 enzymes, which could raise levels of those medications; this effect hasn't been seen in humans yet, but it's a Moderate-level concern.
Choline carries a Minor interaction with atropine, a medication sometimes used for eye exams or certain stomach conditions — choline might reduce atropine's effects in the brain.
Read the full breakdown — every affected drug type, severity by severity
Although we've identified potential interactions with astaxanthin's liver-enzyme effects and choline's interaction with atropine, we cannot fully assess this product's safety with your specific medications because we lack data on the krill oil fatty acids themselves. Altogether, these interactions span 682 individual medications.
Before you start this supplement, run your current medications through the interaction checker on this page. If you take anything metabolized by CYP3A4 or CYP2B6 enzymes — a category that includes many common drugs — or if you use atropine, talk it over with your doctor or pharmacist first.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Omega 3 Krill Oil?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Omega 3 Krill Oil interact with 848 drugs. Click any drug to see the details.
2 of the 3 ingredients in Omega 3 Krill Oil interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin SuperbaBoost Krill Oil
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
Superbaboost Krill OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Superbaboost Krill Oil + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
Superbaboost Krill OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Superbaboost Krill Oil + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
Superbaboost Krill OilAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking krill oil with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Superbaboost Krill Oil + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
Superbaboost Krill OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Superbaboost Krill Oil + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
Superbaboost Krill OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Superbaboost Krill Oil + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Omega 3 Krill Oil — through 2 ingredients. Tap an ingredient for the detail:
Superbaboost Krill OilAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Superbaboost Krill Oil + Acetaminophen, Aspirin, Caffeine interactionAstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Omega 3 Krill Oil — through 1 ingredient. Tap an ingredient for the detail:
AstaxanthinCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
Read the full Astaxanthin + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Omega 3 Krill Oil with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Astaxanthin
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.
SuperbaBoost Krill Oil
Anticoagulant/Antiplatelet Drugs
Theoretically, krill oil may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Taking high doses of omega-3 fatty acids from fish oil can modestly decrease platelet aggregation. Since krill oil also contains these fatty acids, taking high doses of krill oil might also inhibit platelet aggregation. Theoretically, taking high doses of krill oil with antiplatelet or anticoagulant drugs might increase the risk of bleeding. However, the omega-3 content of krill oil is much lower than that of fish oil.
Antidiabetes Drugs
Theoretically, taking krill oil with antidiabetes drugs might increase the risk of hypoglycemia.
Some research in animals and humans shows that krill oil might lower blood glucose levels. However, a small study shows that taking krill oil does not reduce blood glucose levels in patients with type 2 diabetes, most of whom were taking antidiabetes drugs.
Brand information
Manufacturer and brand details for Omega 3 Krill Oil, from the product label.
Crystal Star
See all Crystal Star products- Name
- Healthy Healing Enterprises, LLC
- City
- Minneapolis
- State
- MN
- Phone Number
- 800-736-6015
- Web Address
- WWW.CRYSTALSTAR.COM
Omega 3 Krill Oil by Crystal Star: Common Questions
Does Omega 3 Krill Oil by Crystal Star interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What are the most common side effects from astaxanthin?
Does choline in this product have side effects?
What is astaxanthin supposed to do?
What is choline for in this product?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Omega 3 Krill Oil is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Omega 3 Krill Oil’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Astaxanthin
Interacts with 671 drugsAstaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...
Read the full Astaxanthin monograph → Herb & supplement monographKrill Oil
Interacts with 208 drugsKrill oil is a source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may help absorption. It is most studied for lowering triglycerides and supporting heart health, but t...
Read the full Krill Oil monograph → Herb & supplement monographCholine
Interacts with 16 drugsCholine is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...
Read the full Choline monograph →Sources & How We Checked
Omega 3 Krill Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Astaxanthin 3 references
- Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
- Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
- Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed
Choline 14 references
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
- Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
- Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
- Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
- Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
- Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
- Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
- Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
- Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
- Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
- Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
- Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
- Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.
Krill Oil 13 references
- Leaf A. On the reanalysis of the GISSI-Prevenzione. Circulation 2002;105:1874-5. PubMed
- Connor WE. n-3 Fatty acids from fish and fish oil: panacea or nostrum? Am J Clin Nutr 2001;74;415-6. PubMed
- Calder PC. N-3 polyunsaturated fatty acids, inflammation and immunity: pouring oil on troubled waters or another fishy tale? Nutr Res 2001;21:309-41. DOI
- Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Altern Med Rev 2004;9:420-8.
- Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Altern Med Rev 2003;8:171-9.
- Harris WS, Miller M, Tighe AP, et al. Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives. Atherosclerosis 2008;197:12-24. PubMed
- Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic steatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. J Agric Food Chem 10-14-2009;57:9339-45. PubMed
- Maki, K. C., Reeves, M. S., Farmer, M., Griinari, M., Berge, K., Vik, H., Hubacher, R., and Rains, T. M. Krill oil supplementation increases plasma concentrations of eicosapentaenoic and docosahexaenoic acids in overweight and obese men and women. Nutr.R PubMed
- Albert BB, Derraik JG, Brennan CM, et al. Supplementation with a blend of krill and salmon oil is associated with increased metabolic risk in overweight men. Am J Clin Nutr 2015;102(1):49-57.
- Berge K, Musa-Veloso K, Harwood M, Hoem N, Burri L. Krill oil supplementation lowers serum triglycerides without increasing low-density lipoprotein cholesterol in adults with borderline high or high triglyceride levels. Nutr Res 2014;34(2):126-33. PubMed
- Lobraico JM, DiLello LC, Butler AD, Cordisco ME, Petrini JR, Ahmadi R. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Res Care. 2015 PubMed
- van der Wurff ISM, von Schacky C, Bergeland T, Zeegers MP, Kirschner PA, de Groot RHM. Krill oil supplementation's effect on school grades in typically developing adolescents. Prostaglandins Leukot Essent Fatty Acids 2023;191:102553. PubMed
- van der Wurff ISM, von Schacky C, Bergeland T, et al. Effect of 1 year krill oil supplementation on cognitive achievement of Dutch adolescents: A double-blind randomized controlled trial. Nutrients. 2019;11(6):1230. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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