Organic Astragalus Extract Ingredients & Drug Interactions
by Dr. Mercola
What is this page for?
First and foremost: checking Organic Astragalus Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Organic Astragalus Extract is a dietary supplement by Dr. Mercola with 1 active ingredient. Its ingredients are commonly taken for immune support, colds and flu, upper respiratory infections.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astragalus Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Organic Astragalus Extract by Dr. Mercola
Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Astragalus Extract by Dr. Mercola — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Organic Astragalus Extract by Dr. Mercola
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- “Astragalus Root Extract” is listed as a grouped ingredient — the label gives one combined amount (300 mg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Organic Astragalus Extract, straight from the product label.
| Brand | Dr. Mercola |
|---|---|
| Barcode (UPC) | 810487033497 |
| Net contents | 60 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2025 |
| DSLD ID | 327133 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Organic |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Organic Astragalus Extract by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Polysaccharides | 150 mg | -- |
| Astragalus Root Extract | 300 mg | -- |
Other ingredients: Agave Fiber, Rice Husk, Gum Acacia, Rice Bran Extract, Guar Gum, Sunflower Oil, Tapioca Maltodextrin, Agave Syrup, Sunflower Lecithin, Palm Oil
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: Adults, as a dietary supplement, take one (1) tablet twice daily with a meal.
Precautions
Keep out of reach of children.
Do not use if safety seal is broken.
If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.
Seals/Symbols
USDA Organic
FDA Statement of Identity
Dietary Supplement
Formulation
Certified Organic by: Quality Assurance International
General Statements
Providing quality products since 2001.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Organic Astragalus Extract by Dr. Mercola label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Organic Astragalus Extract by Dr. Mercola
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Astragalus Root Extract
Interacts with208 drugs
Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...
Astragalus Root Extract monograph & interactions- › Polysaccharides
Other (inactive) ingredients: Agave Fiber, Rice Husk, Gum Acacia, Rice Bran Extract, Guar Gum, Sunflower Oil, Tapioca Maltodextrin, Agave Syrup, Sunflower Lecithin, Palm Oil. These complete the product’s ingredient list but are not active constituents.
Organic Astragalus Extract by Dr. Mercola Drug Interactions
Organic Astragalus Extract contains a single active ingredient, and it has known interactions with 208 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Organic Astragalus Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Organic Astragalus Extract interact with 208 drugs. Click any drug to see the details.
1 of the 1 ingredient in Organic Astragalus Extract interact with drugs. Each result below shows which ingredient is responsible. Astragalus Root Extract
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Acetohexamide interactionAdalimumabHumira
How Adalimumab interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Alemtuzumab interactionAlogliptinNesina
How Alogliptin interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Alogliptin, Pioglitazone interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Anifrolumab-fnia interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus Root Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Antithymocyte Globulin interactionAtezolizumabTecentriq
How Atezolizumab interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Atezolizumab interactionAzamuneImmunoprin
How Azamune interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Azamune interactionAzathioprineAzamune, Imuran
How Azathioprine interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Azathioprine interactionBasiliximabSimulect
How Basiliximab interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Basiliximab interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Beclomethasone Dipropionate interactionBetamethasoneCelestone, Diprolene AF, Diprosone
How Betamethasone interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Betamethasone interactionBetamethasone DipropionateSernivo
How Betamethasone Dipropionate interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Betamethasone Dipropionate interactionBetamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
How Betamethasone Dipropionate, Calcipotriene interacts with Organic Astragalus Extract — through 1 ingredient. Tap an ingredient for the detail:
Astragalus Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus Root Extract + Betamethasone Dipropionate, Calcipotriene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Organic Astragalus Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Astragalus Root Extract
Antidiabetes Drugs
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.
Cyclophosphamide
Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.
Immunosuppressants
Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.
Lithium
Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.
Brand information
Manufacturer and brand details for Organic Astragalus Extract, from the product label.
Dr. Mercola
See all Dr. Mercola products- Name
- NHP
- Street Address
- 125 SW 3rd Place
- City
- Cape Coral
- State
- FL
- ZipCode
- 33991
- Phone Number
- (877) 985-2696
Organic Astragalus Extract by Dr. Mercola: Common Questions
Does Organic Astragalus Extract by Dr. Mercola interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Organic Astragalus Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Organic Astragalus Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Organic Astragalus Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 13 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Astragalus 13 references
- Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
- Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
- Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
- Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
- Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
- Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
- Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
- Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
- Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
- Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
- Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
- Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
- Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC