Organic Fennel Powder Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Organic Fennel Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Organic Fennel Powder is a dietary supplement by Banyan Botanicals with 1 active ingredient. Its ingredients are commonly taken for digestive upset and bloating, infant colic, menstrual cramps.Based on those ingredients, 740 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fennel seed powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Organic Fennel Powder by Banyan Botanicals
Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Fennel Powder by Banyan Botanicals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Organic Fennel Powder by Banyan Botanicals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: fennel seed powder. Fennel has a long history in culinary and herbal use and contains compounds with mild estrogenic properties — meaning they weakly mimic the hormone estrogen in the body.
There are no other inactive ingredients listed.
Does it work?
Moderate evidence
Fennel is possibly effective for dysmenorrhea (painful menstrual periods). For other uses — bronchitis, anxiety, nocturnal enuresis (bedwetting), and cholera — the evidence we hold is insufficient to rate it.
How safe is it?
Well-documented data
Fennel powder is generally well tolerated when used as food. Most side effects are mild: gastrointestinal discomfort, photosensitivity, and allergic reactions in sensitive individuals.
Rarely, seizures have been reported. Because this is a concentrated supplement (not just culinary fennel), you should be aware that the safety data during pregnancy and breastfeeding is limited.
The product facts advise against medicinal or concentrated amounts of fennel in pregnancy due to possible hormone-like effects and limited safety data. During breastfeeding, food amounts are likely fine, but medicinal doses haven't been well studied — talk with your pharmacist or doctor if you're nursing and want to use fennel powder.
Meds to double-check
Moderate interaction found
Before taking this fennel powder, double-check with your doctor or pharmacist if you take blood thinners (anticoagulants or antiplatelet drugs), contraceptive medications, hormone replacement therapy, the antibiotic ciprofloxacin (Cipro), tamoxifen (Nolvadex), or any drugs metabolized by the liver enzyme CYP3A4 — all carry moderate interaction risk with fennel.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Fennel powder may be worth considering if you're looking into natural support for period pain, though the evidence is preliminary. If you take blood thinners, hormonal contraceptives, hormone replacement therapy, ciprofloxacin, or tamoxifen, you'll want to check with your doctor or pharmacist first — fennel can interfere with these.
Pregnant or nursing? Discuss this with your healthcare provider before adding it to your routine.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Organic Fennel Powder, straight from the product label.
| Brand | Banyan Botanicals |
|---|---|
| Net contents | 0 Not Present |
| Market status | On market |
| Date entered into DSLD | Apr 25, 2019 |
| DSLD ID | 199537 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | No Claim |
| Intended target group(s) | Adult (18 - 50 Years), Organic |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Organic Fennel Powder by Banyan Botanicals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Fennel seed powder | 0.5 Teaspoon(s) | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Ayurvedic herbs
Formula
(Foeniculum vulgare)
Suggested/Recommended/Usage/Directions
Suggested use: 1/4 to 1/2 teaspoon with warm water, once or twice daily, or as directed by your health practitioner.
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
2011 Banyan Botanicals
Formulation
Certified Organic by New Mexico Department of Agriculture
Seals/Symbols
USDA Organic
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Organic Fennel Powder by Banyan Botanicals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Organic Fennel Powder by Banyan Botanicals
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.5 Teaspoon(s) Dosage formPowder Amounts shown are per serving.
Fennel seed powder
Interacts with740 drugs
Fennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramps. Some sm...
Fennel seed powder monograph & interactionsOrganic Fennel Powder by Banyan Botanicals Drug Interactions
HelloPharmacist Interaction Report
Banyan Botanicals' Organic Fennel Powder can interact with a number of medications through its fennel seed content.
The most serious documented concern involves blood thinners (anticoagulant and antiplatelet drugs) — fennel may increase bleeding risk. Animal research suggests fennel has antiplatelet effects, though human data is limited.
Read the full breakdown — every affected drug type, severity by severity
Fennel also has moderate interactions with contraceptive drugs, hormone replacement therapy (estrogens), and the antibiotic ciprofloxacin (Cipro). The contraceptive and estrogen issue stems from fennel's estrogenic compounds, which may compete for estrogen receptors and potentially reduce effectiveness.
Ciprofloxacin levels may drop by roughly half when taken with fennel, likely because fennel contains minerals like calcium, iron, and magnesium that bind the drug. Tamoxifen (Nolvadex), a breast cancer medication, may also lose effectiveness if fennel's estrogenic activity interferes with its antiestrogenic effect.
Additionally, fennel theoretically may increase levels of drugs metabolized by the CYP3A4 liver pathway, though this hasn't been confirmed in humans.
Altogether, these interactions span 741 individual medications. Before adding fennel powder to your routine, check your exact medications with the search tool on this page and confirm with your doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Organic Fennel Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Organic Fennel Powder interact with 740 drugs. Click any drug to see the details.
1 of the 1 ingredient in Organic Fennel Powder interact with drugs. Each result below shows which ingredient is responsible. Fennel seed powder
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel Seed Powder + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel Seed Powder + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel Seed Powder + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel Seed Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel Seed Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Organic Fennel Powder — through 1 ingredient. Tap an ingredient for the detail:
Fennel Seed PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel Seed Powder + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Organic Fennel Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Fennel seed powder
Anticoagulant/Antiplatelet Drugs
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Animal research suggests that fennel oil has antithrombotic and antiplatelet effects.
Ciprofloxacin (Cipro)
Theoretically, fennel might decrease the levels and clinical effects of ciprofloxacin.
Animal research shows that fennel reduces ciprofloxacin bioavailability by nearly 50%, possibly due to the metal cations such as calcium, iron, and magnesium contained in fennel. This study also found that fennel increased tissue distribution and slowed elimination of ciprofloxacin.
Contraceptive Drugs
Theoretically, taking large amounts of fennel might decrease the effects of contraceptive drugs due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
In vitro research suggests that fennel inhibits CYP3A4 enzyme activity. This effect has not been reported in humans.
Estrogens
Theoretically, taking large amounts of fennel might interfere with hormone replacement therapy due to competition for estrogen receptors.
Some constituents of fennel have estrogenic activity.
Tamoxifen (Nolvadex)
Theoretically, taking large amounts of fennel might decrease the antiestrogenic effect of tamoxifen.
Some constituents of fennel have estrogenic activity, which may interfere with the antiestrogenic activity of tamoxifen.
Brand information
Manufacturer and brand details for Organic Fennel Powder, from the product label.
Banyan Botanicals
See all Banyan Botanicals products- Name
- Banyan Botanicals
- City
- Albuquerque
- State
- NM
- ZipCode
- 87113
- Phone Number
- 1-800-953-6424
- Web Address
- www.banyanbotanicals.com
Organic Fennel Powder by Banyan Botanicals: Common Questions
Does Organic Fennel Powder by Banyan Botanicals interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on birth control?
Is fennel powder safe during pregnancy?
What does fennel actually do?
Can I take this if I'm on a blood thinner?
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Can I take this while breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Organic Fennel Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Organic Fennel Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Organic Fennel Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 17 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fennel 17 references
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
- Gral N, Beani JC, Bonnot D, et al. [Plasma levels of psoralens after celery ingestion]. Ann Dermatol Venereol 1993;120:599-603.
- Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
- Rosti L, Nardini A, Bettinelli ME, Rosti D. Toxic effects of a herbal tea mixture in two newborns. Acta Paediatrica 1994;83:683. PubMed
- Cuzzolin L, Zaffani S, and Benoni G. Safety implications regarding use of phytomedicines. Eur.J Clin Pharmacol. 2006;62:37-42. PubMed
- Tognolini, M., Ballabeni, V., Bertoni, S., Bruni, R., Impicciatore, M., and Barocelli, E. Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis. Pharmacol.Res 2007;56(3):254-260. PubMed
- Subehan, Usia, T., Iwata, H., Kadota, S., and Tezuka, Y. Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants. J Ethnopharmacol. 5-24-2006;105(3):449-455. PubMed
- Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
- Subehan, Zaidi, S. F., Kadota, S., and Tezuka, Y. Inhibition on human liver cytochrome P450 3A4 by constituents of fennel (Foeniculum vulgare): identification and characterization of a mechanism-based inactivator. J Agric.Food Chem. 12-12-2007;55(25):101 PubMed
- LEVY, S. B. Bronchial asthma due to ingestion of fennel and fennel seed. Ann.Allergy 1948;6(4):415.
- Ottolenghi, A., De Chiara, A., Arrigoni, S., Terracciano, L., and De Amici, M. [Diagnosis of food allergy caused by fruit and vegetables in children with atopic dermatitis]. Pediatr Med Chir 1995;17(6):525-530.
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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