Organic Sitopaladi Powder Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Organic Sitopaladi Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Organic Sitopaladi Powder is a dietary supplement by Banyan Botanicals with 5 active ingredients. Its ingredients are commonly taken for digestive upset, respiratory and cough complaints, boosting absorption of other supplements.Based on those ingredients, 1,073 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pippali, Cinnamon, Banslochan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Organic Sitopaladi Powder by Banyan Botanicals
Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Sitopaladi Powder by Banyan Botanicals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Organic Sitopaladi Powder by Banyan Botanicals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Organic Sitopaladi Powder contains 5 active ingredients: pippali (Indian long pepper), cinnamon, cardamom, bamboo, and cane sugar. These are traditional Ayurvedic ingredients combined to support respiratory and digestive wellness, though effectiveness evidence for most conditions is not well established.
The powder also contains tapioca starch as an inactive ingredient (a binder).
Does it work?
Couldn't assess
The evidence we hold for the ingredients in this blend doesn't clearly support their use for any specific condition yet. Pippali, cinnamon, and bamboo all show insufficient reliable evidence to rate for conditions like bronchitis, asthma, diabetes, and liver disease.
Cardamom similarly lacks established evidence for fatty liver disease, respiratory infections, diabetes, indigestion, and high cholesterol. This doesn't mean the product won't help — it means clinical trials backing these claims haven't been completed or aren't strong enough to draw firm conclusions.
How safe is it?
Well-documented data
Pippali and cinnamon are generally well tolerated in food amounts, but concentrated supplement doses lack strong safety data. Pippali is traditionally discouraged at medicinal doses during pregnancy and breastfeeding due to limited study.
Cinnamon in food amounts is likely safe in pregnancy, but high-dose supplements are best avoided; the spice contains coumarin, which in very large amounts over time might stress the liver — though typical supplement doses in clinical trials haven't shown this effect. Cardamom in food amounts is generally well tolerated; one trial reported mild skin inflammation in one participant.
Bamboo supplements are poorly studied for safety; raw shoots can contain cyanide compounds (eliminated by cooking), and concentrated forms are not recommended in pregnancy or while breastfeeding without your doctor's clearance. One case of contact dermatitis from bamboo shoots has been reported.
Meds to double-check
Moderate interaction found
Check before taking this product if you're on blood thinners or antiplatelet drugs (moderate risk of increased bleeding from pippali), diabetes medications (pippali and cinnamon may lower blood sugar), heart rate or blood pressure drugs processed by your liver (pippali and cinnamon may raise their levels), immunosuppressants like cyclosporine, theophylline for breathing, pentobarbital or other sedatives, or medications that are sensitive to liver stress. No interactions are documented for cardamom or bamboo in our data.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a traditional Ayurvedic blend, but effectiveness evidence for most of its claimed uses isn't established yet. If you take diabetes medications, blood thinners, heart drugs, or anything processed by your liver, talk with your pharmacist or doctor before starting — pippali and cinnamon can shift how these work.
Avoid medicinal doses during pregnancy or breastfeeding unless your healthcare provider advises it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Organic Sitopaladi Powder, straight from the product label.
| Brand | Banyan Botanicals |
|---|---|
| Net contents | 0 Not Present |
| Market status | On market |
| Date entered into DSLD | Feb 25, 2019 |
| DSLD ID | 199878 |
| Product type | Botanical With Nutrients |
| Supplement form | Powder |
| Dietary claims / uses | No Claim |
| Intended target group(s) | Adult (18 - 50 Years), Organic |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Organic Sitopaladi Powder by Banyan Botanicals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Cane Sugar | 0 NP | -- |
| Proprietary Blend | 0.5 Teaspoon(s) | -- |
| Pippali | 0 NP | -- |
| Cinnamon | 0 NP | -- |
| Cardamom | 0 NP | -- |
| Banslochan | 0 NP | -- |
Other ingredients: Tapioca Starch
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Ayurvedic herbs
Suggested/Recommended/Usage/Directions
Suggested use: 1/4 to 1/2 teaspoon with warm water, once or twice daily, or as directed by your health practitioner.
FDA Statement of Identity
Dietary Supplement
Brand IP Statement(s)
2011 Banyan Botanicals
Formulation
Certified Organic by New Mexico Department of Agriculture
Seals/Symbols
USDA Organic
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Organic Sitopaladi Powder by Banyan Botanicals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Organic Sitopaladi Powder by Banyan Botanicals
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.5 Teaspoon(s) Dosage formPowder Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › Cane Sugar
- › Pippali
- › Cinnamon
- › Cardamom
- › Banslochan
Other (inactive) ingredients: Tapioca Starch. These complete the product’s ingredient list but are not active constituents.
Organic Sitopaladi Powder by Banyan Botanicals Drug Interactions
HelloPharmacist Interaction Report
Organic Sitopaladi Powder by Banyan Botanicals does interact with medications, primarily through its pippali (Indian long pepper) and cinnamon content.
The most serious documented concern is a moderate-severity risk of increased bleeding when pippali is combined with blood thinners or antiplatelet drugs — pippali can slow platelet clumping, which adds to the effect of these medications.
Read the full breakdown — every affected drug type, severity by severity
Pippali also moderately interacts with diabetes medications, heart drugs processed by your liver (CYP3A4 substrates), blood pressure medications like propranolol, theophylline (a breathing medicine), cyclosporine (an immunosuppressant), pentobarbital (a sedative), and medications moved by a cellular pump called P-glycoprotein. Cinnamon similarly carries moderate concerns with diabetes drugs and medications that stress the liver (hepatotoxic drugs).
Neither ingredient's interactions are necessarily deal-breakers, but they do mean blood sugar, drug levels, and liver function may need closer watching.
Cardamom and bamboo have no interactions documented in our data, though we could not check cane sugar. Altogether, these interactions span 1,074 individual medications.
Run your exact prescriptions through the interaction checker on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Organic Sitopaladi Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Organic Sitopaladi Powder interact with 1,073 drugs. Click any drug to see the details.
3 of the 5 ingredients in Organic Sitopaladi Powder interact with drugs. Each result below shows which ingredient is responsible. Pippali Cinnamon Banslochan
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Ado-trastuzumab Emtansine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
PippaliAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Pippali + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Abiraterone interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abiraterone Acetate interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
PippaliAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Pippali + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
PippaliAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Pippali + Acarbose interactionCinnamonAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Read the full Cinnamon + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
PippaliAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Pippali + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
PippaliAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Pippali + Acetaminophen, Aspirin interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Aspirin, Caffeine interactionPippaliAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Pippali + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Caffeine interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Butalbital, Caffeine, Codeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Organic Sitopaladi Powder — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Codeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Dihydrocodeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Isometheptene interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Pyrilamine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Organic Sitopaladi Powder — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Organic Sitopaladi Powder with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Pippali
Anticoagulant/Antiplatelet Drugs
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that Indian long pepper extract inhibits platelet aggregation.
Antidiabetes Drugs
Theoretically, Indian long pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that piperine, a constituent of Indian long pepper, can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Cyclosporine (Neoral, Sandimmune)
Theoretically, Indian long pepper might increase the effects and adverse effects of cyclosporine.
In vitro research shows that piperine, a constituent of Indian long pepper, increases the bioavailability of cyclosporine.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
In vitro research shows that piperine, a constituent of Indian long pepper, inhibits CYP3A4.
Nevirapine (Viramune)
Theoretically, Indian long pepper might increase blood levels of nevirapine.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases the plasma concentration and systemic exposure of nevirapine. However, no adverse effects were associated with the elevated plasma levels of nevirapine.
P-Glycoprotein Substrates
Theoretically, Indian long pepper might increase levels of P-glycoprotein substrates.
In vitro research shows that piperine, a constituent of Indian long pepper, can inhibit P-glycoprotein.
Pentobarbital (Nembutal)
Theoretically, Indian long pepper might increase the sedative effects of pentobarbital.
Animal research shows that piperine, a constituent of Indian long pepper, can increase pentobarbitone-induced sleeping time.
Phenytoin (Dilantin)
Theoretically, Indian long pepper might increase blood levels of phenytoin.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases phenytoin serum levels and slows its elimination.
Propranolol (Inderal)
Theoretically, Indian long pepper might increase blood levels of propranolol.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, accelerates absorption and increases serum concentrations of propranolol.
Rifampin (Rifadin)
Theoretically, Indian long pepper might increase blood levels of rifampin.
Piperine, a constituent of Indian long pepper, seems to increase absorption and serum levels of rifampin.
Theophylline
Indian long pepper might increase blood levels of theophylline.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases serum concentrations and slows elimination of theophylline.
Amoxicillin (Amoxil, Trimox)
Theoretically, Indian long pepper might increase the effects and adverse effects of amoxicillin.
Evidence from animal research shows that piperine, a constituent of Indian long pepper, increases the plasma levels of amoxicillin when taken concomitantly.
Carbamazepine (Tegretol)
Theoretically, Indian long pepper might increase blood levels of carbamazepine.
A small pharmacokinetic study in patients taking carbamazepine 300 mg or 500 mg twice daily shows that a single 20 mg dose of purified piperine, which is a constituent of Indian long pepper, increases carbamazepine levels. Piperine may increase absorption by increasing blood flow to the GI tract, increasing the surface area of the small intestine, or by cytochrome P450 3A4 (CYP3A4) inhibition in the gut wall. Absorption was significantly increased by 7-10 mcg/mL/hour. The time to eliminate carbamazepine was also increased by 4-8 hours. Although carbamazepine levels were increased, this did not appear to increase side effects.
Cefotaxime (Claforan)
Theoretically, Indian long pepper might increase the effects and adverse effects of cefotaxime.
Animal research shows that piperine, a constituent of Indian long pepper, increases the plasma levels of cefotaxime when taken concomitantly.
Cinnamon
Antidiabetes Drugs
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.
Hepatotoxic Drugs
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.
Banslochan
Antithyroid Drugs
Theoretically, long-term bamboo use might increase the effects and adverse effects of antithyroid drugs, possibly leading to hypothyroidism.
Animal research suggests that long-term consumption of bamboo shoot can decrease thyroid peroxidase activity, as well as levels of thyroxine (T4) and triiodothyronine (T3). This effect has not yet been reported in humans.
Brand information
Manufacturer and brand details for Organic Sitopaladi Powder, from the product label.
Banyan Botanicals
See all Banyan Botanicals products- Name
- Banyan Botanicals
- City
- Albuquerque
- State
- NM
- ZipCode
- 87113
- Phone Number
- 1-800-953-6424
- Web Address
- www.banyanbotanicals.com
Organic Sitopaladi Powder by Banyan Botanicals: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Organic Sitopaladi Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Indian Long Pepper
Interacts with 896 drugsIndian long pepper (pippali) is a spice long used in Ayurvedic medicine and is best known for its piperine content, which may increase how well the body absorbs certain other substances. Mod...
Read the full Indian Long Pepper monograph → Herb & supplement monographCassia Cinnamon
Interacts with 442 drugsCassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...
Read the full Cassia Cinnamon monograph → Herb & supplement monographCardamom
Cardamom is a popular cooking spice that has long been used in traditional medicine for digestion and fresh breath. As a food, it is generally safe for most people, but high-dose supplements...
Read the full Cardamom monograph → Herb & supplement monographBamboo
Interacts with 5 drugsBamboo is a giant grass whose shoots are eaten as food and whose leaves and silica-rich extracts are sold as supplements, often for hair, skin, nail, and bone support. Solid human evidence f...
Read the full Bamboo monograph →Sources & How We Checked
Organic Sitopaladi Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 38 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Indian Long Pepper 12 references
- Bano G, Amla V, Raina RK, et al. The effect of piperine on pharmacokinetics of phenytoin in healthy volunteers. Planta Med 1987;53:568-9. PubMed
- Bano G, et al. Effect of piperine on bioavailability and pharmacokinetics of propranolol and theophylline in healthy volunteers. Eur J Clin Pharmacol 1991;41;615-7. PubMed
- Bhardwaj RK, Glaeser H, Becquemont L, et al. Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4. J Pharmacol Exp Ther 2002;302:645-50. PubMed
- Pattanaik S, Hota D, Prabhakar S, et al. Pharmacokinetic interaction of a single dose of piperine with steady-state carbamazepine in epilepsy patients. Phytother Res 2009;23:1281-6.
- Kasibhatta, R. and Naidu, M. U. Influence of piperine on the pharmacokinetics of nevirapine under fasting conditions: a randomised, crossover, placebo-controlled study. Drugs R.D. 2007;8(6):383-391. PubMed
- Mujumdar, A. M., Dhuley, J. N., Deshmukh, V. K., Raman, P. H., Thorat, S. L., and Naik, S. R. Effect of piperine on pentobarbitone induced hypnosis in rats. Indian J Exp.Biol. 1990;28(5):486-487.
- Panda, S. and Kar, A. Piperine lowers the serum concentrations of thyroid hormones, glucose and hepatic 5'D activity in adult male mice. Horm.Metab Res. 2003;35(9):523-526. PubMed
- Hiwale, A. R., Dhuley, J. N., and Naik, S. R. Effect of co-administration of piperine on pharmacokinetics of beta-lactam antibiotics in rats. Indian J Exp.Biol. 2002;40(3):277-281.
- Han, Y., Chin Tan, T. M., and Lim, L. Y. In vitro and in vivo evaluation of the effects of piperine on P-gp function and expression. Toxicol.Appl.Pharmacol. 8-1-2008;230(3):283-289. PubMed
- Sharma, P., Varma, M. V., Chawla, H. P., and Panchagnula, R. In situ and in vivo efficacy of peroral absorption enhancers in rats and correlation to in vitro mechanistic studies. Farmaco 2005;60(11-12):874-883. PubMed
- Zutshi, R. K., Singh, R., Zutshi, U., Johri, R. K., and Atal, C. K. Influence of piperine on rifampicin blood levels in patients of pulmonary tuberculosis. J Assoc.Physicians India 1985;33(3):223-224.
- Yadav V, Krishnan A, Vohora D. A systematic review on Piper longum L.: Bridging traditional knowledge and pharmacological evidence for future translational research. J Ethnopharmacol. 2020;247:112255. PubMed
Cassia Cinnamon 20 references
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
- De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
- Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
- Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
- Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
- Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
- Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
- Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
- Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
- Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
- Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
- Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
- Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
- Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
- Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
- Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
- Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
- Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
- Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed
Cardamom 2 references
- Mobacken, H. and Fregert, S. Allergic contact dermatitis from cardamom. Contact Dermatitis 1975;1(3):175-176. PubMed
- Aghasi M, Koohdani F, Qorbani M, et al. Beneficial effects of green cardamom on serum SIRT1, glycemic indices and triglyceride levels in patients with type 2 diabetes mellitus: a randomized double-blind placebo controlled clinical trial. J Sci Food Agri PubMed
Bamboo 4 references
- Chandra AK, Ghosh D, Mukhopadhyay S, et al. Effect of bamboo shoot, Bambusa arundinacea (Retz.) Willd. on thyroid status under conditions of varying iodine intake in rats. Indian J Exp Biol 2004;42(8):781-786.
- Kitajima T. Contact allergy caused by bamboo shoots. Contact Dermatitis 1986;15(2):100-102. PubMed
- Sang-A-Gad P, Guharat S, Wananukul W. A mass cyanide poisoning from pickling bamboo shoots. Clin Toxicol (Phila). 2011 Nov;49(9):834-9. PubMed
- Satya S, Bal LM, Singhal P, Naik SN. Bamboo shoot processing: food quality and safety aspect (a review). Trends in Food Sci. Technol. 2010;21(4):181-9. DOI
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC