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Dietary supplement

Organic Guduchi Powder Ingredients & Drug Interactions

by Banyan Botanicals

Organic Guduchi Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Guduchi Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Guduchi Powder is a dietary supplement by Banyan Botanicals with 1 active ingredient. Its ingredients are commonly taken for immune support, fever, blood sugar support.Based on those ingredients, 612 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Guduchi stem powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Guduchi Powder by Banyan Botanicals

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Guduchi Powder by Banyan Botanicals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Guduchi Powder by Banyan Botanicals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 27, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: guduchi stem powder (Tinospora cordifolia). In traditional medicine, guduchi has been used to support overall wellness and resilience.

There are no added inactive ingredients in this formula.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Tinospora Cordifolia's overall clinical evidence instead.

Moderate

Some clinical evidence supports Tinospora Cordifolia for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Diabetes — rated "Possibly Effective" (Natural Medicines).

The evidence we hold shows that guduchi is possibly effective for type 2 diabetes — clinical research found it can lower fasting blood sugar and a marker of long-term blood sugar control. For hay fever, asthma, athletic performance, cancer, and hepatitis, the evidence available to us is insufficient to rate whether it works.

If you're considering it for a condition beyond diabetes, talk with your doctor about what the current science actually supports.

The evidence, ingredient by ingredient Tinospora Cordifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

When taken by mouth, guduchi powder is generally well tolerated. The most common side effects reported were headache and nasal pain, affecting a small number of people in trials.

However, liver injury — including autoimmune hepatitis, acute hepatitis, and in rare cases liver failure — has been reported after use. In two case series, 49 patients developed serious liver problems after consuming guduchi alone or in combination products for a median of 42 to 90 days; two required transplants and four died.

Because of this risk, use it only under guidance and monitor for warning signs like yellowing of skin or eyes, dark urine, or unusual fatigue. During pregnancy, safety has not been established, so it is best avoided.

The same applies to breastfeeding — there isn't enough reliable safety information, so avoid use while nursing. If you're pregnant or breastfeeding and considering guduchi, talk with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Tinospora Cordifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tinospora Cordifolia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 612 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take any drugs broken down by your liver, including those processed through CYP2D6, CYP2C19, CYP1A2, or CYP2C9 pathways. You should also double-check if you take diabetes medications (insulin or oral drugs) or immunosuppressants for organ transplant or autoimmune disease.

Use the medication search tool on this page to see if your specific medications are affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Guduchi powder may be worth considering if you have type 2 diabetes and want an option studied for blood sugar control, but its interactions with liver metabolism, diabetes drugs, and immune-suppressing medications are significant. The rare but serious risk of liver injury also means you should use it only under guidance and watch for warning signs.

Before starting, check your medications against the tool on this page and discuss it with your doctor or pharmacist — especially if you take any prescription drugs, have liver disease, or are pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Guduchi Powder, straight from the product label.

Brand Banyan Botanicals
Net contents 0 Not Present
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 199609
Product type Botanical
Supplement form Powder
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Guduchi Powder by Banyan Botanicals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 Teaspoon(s)
Maximum serving Sizes:
0.5 Teaspoon(s)
IngredientAmount% DV
Guduchi stem powder0.5 Teaspoon(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Ayurvedic herbs

Formula

(Tinospora cordifolia)

Suggested/Recommended/Usage/Directions

Suggested use: 1/4 to 1/2 teaspoon with warm water, once or twice daily, or as directed by your health practitioner.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

2011 Banyan Botanicals

Formulation

Certified Organic by New Mexico Department of Agriculture

Seals/Symbols

USDA Organic

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Guduchi Powder by Banyan Botanicals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Guduchi Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Guduchi Powder by Banyan Botanicals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 Teaspoon(s) Dosage formPowder Amounts shown are per serving.

Guduchi stem powder

Interacts with
612 drugs
0.5 Teaspoon(s) per serving

Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Ea...

Guduchi stem powder monograph & interactions
Interaction report

Organic Guduchi Powder by Banyan Botanicals Drug Interactions

Want to check YOUR meds against Organic Guduchi Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
612Drugs
612 Moderate

Ingredients driving the most interactions

Guduchi stem powder 612

Individual Drug Interactions

The ingredients in Organic Guduchi Powder interact with 612 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Guduchi Powder interact with drugs. Each result below shows which ingredient is responsible. Guduchi stem powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Guduchi Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Guduchi stem powder6 drug types · 612 drugs

Antidiabetes Drugs

Theoretically, Tinospora cordifolia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research in adults with type 2 diabetes shows that Tinospora cordifolia can reduce fasting blood glucose and glycated hemoglobin. Additionally, animal research shows that Tinospora cordifolia has hypoglycemic effects.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that Tinospora cordifolia extract inhibits CYP1A2 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C19 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C9. Animal research shows that Tinospora cordifolia extract 400 mg/kg twice daily for 14 days reduces the clearance and increases plasma levels of glyburide, a CYP2C9 substrate. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2D6 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.
In vitro and animal research shows that Tinospora cordifolia has immunostimulant effects.

Likelihood Possible Evidence D
Guduchi stem powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Guduchi Powder, from the product label.

Banyan Botanicals

See all Banyan Botanicals products
Name
Banyan Botanicals
City
Albuquerque
State
NM
ZipCode
87113
Phone Number
1-800-953-6424
Web Address
www.banyanbotanicals.com
Pharmacist Counseling Corner

Organic Guduchi Powder by Banyan Botanicals: Common Questions

Does Organic Guduchi Powder by Banyan Botanicals interact with any medications?
Yes. Based on its ingredients, Organic Guduchi Powder has a known interaction with 612 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Guduchi Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take guduchi if I have type 2 diabetes?
Guduchi has been studied in people with type 2 diabetes and shown it can lower blood sugar. However, if you already take diabetes medications, combining them could increase your risk of low blood sugar (hypoglycemia). Talk with your doctor before adding guduchi — your medication doses may need adjusting, and you may need to monitor your blood sugar more closely.
What are the side effects of guduchi powder?
When taken by mouth, guduchi is generally well tolerated. The most common side effects reported in trials were headache and nasal pain. The serious concern is liver injury, which is rare but has been reported — including autoimmune hepatitis and, in a few cases, acute liver failure. Watch for yellowing of skin or eyes, dark urine, or unusual fatigue, and talk with your doctor right away if these occur.
Is it safe to take guduchi while pregnant or breastfeeding?
Safety has not been established in pregnancy, so it is best avoided during pregnancy. There isn't enough reliable safety information to use it while breastfeeding either, so avoid it then as well. If you're pregnant or breastfeeding, talk with your doctor or pharmacist before considering guduchi.
What is guduchi used for?
In traditional medicine, guduchi has been used to support overall wellness and resilience. The evidence we hold shows it's possibly effective for type 2 diabetes. For other uses like hay fever, asthma, athletic performance, cancer, and hepatitis, the evidence available to us is insufficient to say whether it works.
Does guduchi interact with blood thinners or other medications?
Guduchi may slow how your liver breaks down many medications, including drugs processed through CYP2D6, CYP2C19, CYP1A2, and CYP2C9 pathways — potentially raising their levels in your blood. It may also interfere with diabetes drugs and immunosuppressants. Use the medication checker on this page to see if your specific drugs are affected, and talk with your doctor or pharmacist before starting.
Why should I be concerned about liver injury?
Liver injury, including autoimmune hepatitis and acute liver failure, has been reported in patients taking guduchi. In two case series, 49 patients developed serious liver problems after using guduchi for a median of 42 to 90 days — some required transplants. While rare, this risk means you should use guduchi only under guidance and watch closely for warning signs like yellowing of skin, dark urine, or unusual fatigue.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Guduchi Powder label
Go deeper

The Full Monographs Behind Organic Guduchi Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tinospora Cordifolia

Interacts with 612 drugs

Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Early laboratory and small human studies s...

Read the full Tinospora Cordifolia monograph →
Sources

Sources & How We Checked

Organic Guduchi Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 16 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tinospora Cordifolia 16 references
  1. Stanely Mainzen Prince P, Menon VP. Hypoglycaemic and hypolipidaemic action of alcohol extract of Tinospora cordifolia roots in chemical induced diabetes in rats. Phytother Res 2003;17:410-3.
  2. Grover JK, Vats V, Rathi SS. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol 2000;73:461-70. PubMed
  3. Manjrekar PN, Jolly CI, Narayanan S. Comparative studies of the immunomodulatory activity of Tinospora cordifolia and Tinospora sinensis. Fitoterapia 2000;71:254-7. PubMed
  4. Prince PS, Menon VP. Antioxidant activity of Tinospora cordifolia roots in experimental diabetes. J Ethnopharmacol 1999;65:277-81. PubMed
  5. Stanely Mainzen Prince P, Menon VP, Gunasekaran G. Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats. J Ethnopharmacol 1999;64:53-7. PubMed
  6. Badar VA, Thawani VR, Wakode PT, et al. Efficacy of Tinospora cordifolia in allergic rhinitis. J Ethnopharmacol 2005;96:445-9. PubMed
  7. Kapil A, Sharma S. Immunopotentiating compounds from Tinospora cordifolia. J Ethnopharmacol 1997;58:89-95. PubMed
  8. Nair PK, Rodriguez S, Ramachandran R, et al. Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia. Int Immunopharmacol 2004;4:1645-59. PubMed
  9. Castillo AL, Osi MO, Ramos JD, De Francia JL, Dujunco MU, Quilala PF. Efficacy and safety of Tinospora cordifolia lotion in Sarcoptes scabiei var hominis-infected pediatric patients: A single blind, randomized controlled trial. J Pharmacol Pharmacother. 2 PubMed
  10. Sahu R, Ahmed T, Sangana R, Punde R, Subudhi BB. Effect of Tinospora cordifolia aqua-alcoholic extract on pharmacokinetic of glibenclamide in rat: an herb-drug interaction study. J Pharm Biomed Anal. 2018;151:310-6. doi: 10.1016/j.jpba.2018.01.010. PubMed
  11. Patial V, Katoch S, Chhimwal J, Singh PP, Suresh PS, Padwad Y. Tinospora cordifolia activates PPAR? pathway and mitigates glomerular and tubular cell injury in diabetic kidney disease. Phytomedicine 2021;91:153663. PubMed
  12. Kulkarni AV, Hanchanale P, Prakash V, et al. Tinospora Cordifolia (Giloy)-Induced Liver Injury During the COVID-19 Pandemic-Multicenter Nationwide Study From India. Hepatol Commun 2022;6(6):1289-1300. PubMed
  13. Nagral A, Adhyaru K, Rudra OS, Gharat A, Bhandare S. Herbal Immune Booster-Induced Liver Injury in the COVID-19 Pandemic - A Case Series. J Clin Exp Hepatol. 2021;11(6):732-738. PubMed
  14. Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. PubMed
  15. Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed
  16. May K, Jeitler M, Murthy V, Stapelfeldt E, Kessler CS. A Case Report of Acute Hepatitis Involving the Medicinal Herb Tinospora cordifolia Along with Other Variables. J Integr Complement Med 2023;29(5):327-333.

See these in context on the Tinospora Cordifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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