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Dietary supplement

Organic Lion's Mane Powder Ingredients & Drug Interactions

by Micro Ingredients

Organic Lion's Mane Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Organic Lion's Mane Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Organic Lion's Mane Powder is a dietary supplement by Micro Ingredients with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, nerve health, mood and anxiety.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lion's Mane Entire Fruiting Body, Mycelium Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Organic Lion's Mane Powder by Micro Ingredients

Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Lion's Mane Powder by Micro Ingredients — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Organic Lion's Mane Powder by Micro Ingredients

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains a single active ingredient: lion's mane mushroom extract (both fruiting body and mycelium). There are no other inactive ingredients listed.

Lion's mane is a fungal extract that's been used traditionally and is generally well tolerated when taken by mouth.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lion's Mane Mushroom's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: memory and cognitive support.
  • We looked for evidence on: Memory, Cognitive function, Cognitive impairment, Alzheimer disease, Dementia, Parkinson disease — and 3 related terms.
  • The closest evidence on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease (Natural Medicines).
  • Also on file: Lion's Mane Mushroom is rated "Insufficient Reliable Evidence To Rate" for Cognitive function, Cognitive impairment, Dementia, Memory, and more.

The evidence for lion's mane isn't established in our data. We hold insufficient reliable evidence to rate it for Alzheimer disease, anxiety, athletic performance, cancer, general cognitive function, or cognitive impairment.

That doesn't mean it doesn't work—it means the studies we have aren't robust enough yet to make a confident claim either way.

The evidence, ingredient by ingredient Lion's Mane Mushroom

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, lion's mane is generally well tolerated as a food, though long-term supplement safety hasn't been well studied. The most common side effects in reports are gastrointestinal discomfort, nausea, and skin rash.

However, there isn't enough safety data to recommend it during pregnancy or while breastfeeding—talk to your doctor or pharmacist for personalized guidance if either applies to you.

Side effects, ingredient by ingredient Lion's Mane Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lion's Mane Mushroom.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before using this product, double-check your medications if you take blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel, and others)—lion's mane may increase bleeding risk. Also flag it with your pharmacist if you're on diabetes medications or drugs that suppress your immune system, as the mushroom may interfere with how they work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

Lion's mane may interest you if you're exploring mushroom supplements for cognitive support, but the evidence isn't strong yet. Be especially cautious if you take blood thinners, diabetes medications, or immune suppressants—those need a careful check first.

Run your exact medications through the tool on this page, and ask your pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Organic Lion's Mane Powder, straight from the product label.

Brand Micro Ingredients
Barcode (UPC) X003RVA6TZ
Net contents 1 Pound(s); 454 Gram(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 325595
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Organic Lion's Mane Powder by Micro Ingredients, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.5 Gram(s)
Maximum serving Sizes:
1.5 Gram(s)
Servings per container
302
UPC/BARCODE
X003RVA6TZ
IngredientAmount% DV
Lion's Mane Entire Fruiting Body, Mycelium Extract1.5 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Natural polysaccharides

Why Micro Ingredients Lion's Mane Powder? Savor the superfood power of our sustainably grown, organic Lion's Mane mushroom powder. Meticulously extracted from both the fruit body and mycelium to create a more complete experience, this allows for each serving to retain 30% polysaccharides, along with a rich profile of enzymes, antioxidants, and fibers for maximum health benefits. It is derived from a freeze-drying method that does not require heat to help capture the full true essence of this magnificent mushroom and all of its benefits.

Formulation

GMO free Filler free

USDA Organic

No GMO

Stay healthy Quality assured

Free of: Soy, dairy, gluten & tree nuts.

Certified Organic by Organic Certifiers

Seals/Symbols

USDA Organic

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use As a dietary supplement, take 1 scoop daily. For best results, please consult your physician. One scoop powder offers the same potency as 6 regular capsules Compared to regular lion's mane capsules Regular lion's mane capsules are defined as lion's mane in powder-filled capsules.

Precautions

Keep out of the reach of children.

If pregnant / lactating or taking any medications, please consult your physician prior to use.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Need help? Feel free to contact us at [email protected] Scan me Be kind to our planet and recycle, thank you Follow us on Instagram Facebook Youtube Twitter Snapchat Learn more about us at microingredients.com New

Love nature

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Organic Lion's Mane Powder by Micro Ingredients label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Organic Lion's Mane Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Organic Lion's Mane Powder by Micro Ingredients

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.5 Gram(s) Dosage formPowder Servings per container302 Amounts shown are per serving.

Lion's Mane Entire Fruiting Body, Mycelium Extract

Interacts with
327 drugs
1.5 Gram(s) per serving Form: Hericium erinaceus Fruiting Body Extract, Hericium erinaceus Mycelium Extract

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and...

Lion's Mane Entire Fruiting Body, Mycelium Extract monograph & interactions
Interaction report

Organic Lion's Mane Powder by Micro Ingredients Drug Interactions

Want to check YOUR meds against Organic Lion's Mane Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Lion's Mane Entire Fruiting Body, Mycelium Extract 327

Individual Drug Interactions

The ingredients in Organic Lion's Mane Powder interact with 327 drugs. Click any drug to see the details.

1 of the 1 ingredient in Organic Lion's Mane Powder interact with drugs. Each result below shows which ingredient is responsible. Lion's Mane Entire Fruiting Body, Mycelium Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Organic Lion's Mane Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lion's Mane Entire Fruiting Body, Mycelium Extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, lion's mane mushroom may increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
In vitro research suggests that lion's mane mushroom extracts can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lion's mane mushroom may have additive effects when used with antidiabetes drugs.
Animal research suggests that an aqueous extract of lion's mane mushroom can reduce serum glucose and increase serum insulin.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, concurrent use of lion's mane mushroom might interfere with immunosuppressive therapy.
In animal and in vitro research, lion's mane mushroom polysaccharides stimulate the immune system.

Likelihood Possible Evidence D
Lion's Mane Entire Fruiting Body, Mycelium Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Organic Lion's Mane Powder, from the product label.

Micro Ingredients

See all Micro Ingredients products
Name
Micro Ingredients
Street Address
4951 Holt Blvd, Suite A
City
Montclair
State
CA
ZipCode
91763
Phone Number
1-844-836-8200
Web Address
www.microingredients.com
Pharmacist Counseling Corner

Organic Lion's Mane Powder by Micro Ingredients: Common Questions

Does Organic Lion's Mane Powder by Micro Ingredients interact with any medications?
Yes. Based on its ingredients, Organic Lion's Mane Powder has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Organic Lion's Mane Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take lion's mane if I'm pregnant or breastfeeding?
There isn't enough safety data to know either way. The facts we have advise against it in both cases. Talk with your doctor or pharmacist about whether it's right for you—they know your full picture.
What side effects does lion's mane mushroom cause?
The most common ones reported are gastrointestinal discomfort, nausea, and skin rash. It's generally well tolerated overall, but long-term safety as a supplement hasn't been studied thoroughly.
Does lion's mane actually improve brain function or memory?
The evidence isn't established yet. We hold insufficient reliable evidence to rate it for cognitive function, cognitive impairment, Alzheimer disease, anxiety, or other brain-related uses. That means the studies so far aren't strong enough to say yes or no.
Is this powder just lion's mane, or does it have other ingredients?
Just lion's mane—the entire fruiting body and mycelium extract. There are no other inactive fillers or binders listed.
Will lion's mane interfere with my diabetes medication?
It might. Animal research suggests lion's mane can lower blood sugar levels on its own, so using it with diabetes drugs could add up to a bigger effect. Check with your pharmacist about your specific medication before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Organic Lion's Mane Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Organic Lion's Mane Powder label
Go deeper

The Full Monographs Behind Organic Lion's Mane Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lion's Mane Mushroom

Interacts with 327 drugs

Lion's mane is an edible mushroom that is popular as a 'nootropic' for memory, focus, and nerve health, but solid human evidence is still limited and early. It is generally well tolerated as...

Read the full Lion's Mane Mushroom monograph →
Sources

Sources & How We Checked

Organic Lion's Mane Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lion's Mane Mushroom 6 references
  1. Product information for <em>Niaspan</em>. Abbott Laboratories. North Chicago, IL 60064. April 2015.
  2. Liang B, Guo Z, Xie F, Zhao A. Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complement Altern Med. 2013;13:253. PubMed
  3. Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial. Phytother Res. 2009;23(3):367-72.
  4. Mori K, Kikuchi H, Obara Y, et al. Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine. 2010;17(14):1082-5. PubMed
  5. Li IC, Chang HH, Lin CH, et al. Prevention of early Alzheimer's disease by erinacine A-enriched Hericium erinaceus mycelia pilot double-blind placebo-controlled study. Front Aging Neurosci 2020 Jun 3;12:155. doi: 10.3389/fnagi.2020.00155. PubMed
  6. Tian B, Liu R, Xu T, et al. Modulating effects of Hericium erinaceus polysaccharides on the immune response by regulating gut microbiota in cyclophosphamide-treated mice. J Sci Food Agric 2023;103(6):3050-3064.

See these in context on the Lion's Mane Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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