Organic Shiitake Mushroom 7.5 g Unflavored Ingredients & Drug Interactions
by Nutricost
What is this page for?
First and foremost: checking Organic Shiitake Mushroom 7.5 g Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Organic Shiitake Mushroom 7.5 g Unflavored is a dietary supplement by Nutricost with 1 active ingredient. Its ingredients are commonly taken for immune support, general wellness and nutrition, cholesterol and heart health.Based on those ingredients, 312 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Shiitake Mushroom. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Organic Shiitake Mushroom 7.5 g Unflavored by Nutricost
Ask about any prescription or over-the-counter medication and we check it for interactions with Organic Shiitake Mushroom 7.5 g Unflavored by Nutricost — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Organic Shiitake Mushroom 7.5 g Unflavored by Nutricost
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This is a single-ingredient product: organic shiitake mushroom powder at 7.5 grams per serving. Shiitake is a culinary mushroom with a long history in Asian cooking and traditional medicine.
The powder form is a concentrated supplement, which is different from eating shiitake as food — your body absorbs more of the active compounds this way.
Does it work?
Couldn't assess
The evidence for shiitake mushroom supplements is sparse. For dental plaque, it's rated possibly ineffective.
For cancer prevention or treatment, chemotherapy-related anemia, and atherosclerosis, there isn't enough reliable evidence in our data to rate it one way or another. If you're considering this for a specific health goal, check with your doctor or pharmacist about what the current evidence actually supports for your situation.
How safe is it?
Well-documented data
Shiitake eaten as cooked food is generally well tolerated. Concentrated supplements, though, carry more caution because safety data at supplement doses is limited.
Side effects from the supplement can include abdominal discomfort, bloating, diarrhea, nausea, and vomiting. Raw shiitake is a particular concern — it can cause shiitake dermatitis, a distinctive skin eruption with whiplash-like marks sometimes accompanied by fever or chills.
People who handle shiitake mushrooms extensively, such as growers, may develop allergic reactions (contact dermatitis, asthma, rhinitis, or in rare cases, a lung sensitivity reaction called hypersensitivity pneumonitis with breathing difficulty and chest pain). Large pieces swallowed without proper chewing can, rarely, cause intestinal blockage.
Meds to double-check
Moderate interaction found
Before you take this product, check with your pharmacist about any immunosuppressants (transplant or autoimmune medications) or drugs metabolized by the CYP2D6 enzyme — a group that includes certain antidepressants and cardiac drugs. Shiitake may reduce how well these work.
Use the interaction tool on this page to search your exact medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Shiitake mushroom supplement may be worth trying if you're interested in general immune support, but the evidence for specific health conditions is thin. If you take immunosuppressants or certain psychiatric or heart medications metabolized by CYP2D6, you'll want to run this past your own doctor or pharmacist before starting.
Stick with cooked forms to avoid raw-mushroom skin reactions, and watch for digestive upset.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Organic Shiitake Mushroom 7.5 g Unflavored, straight from the product label.
| Brand | Nutricost |
|---|---|
| Barcode (UPC) | 810014670195 |
| Net contents | 100 Gram(s); 0.22 Pound(s) |
| Market status | On market |
| Date entered into DSLD | Jun 24, 2020 |
| DSLD ID | 223536 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Organic Shiitake Mushroom 7.5 g Unflavored by Nutricost, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| organic Shiitake Mushroom | 7.5 Gram(s) | -- |
Other ingredients: None
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Recommended Use: As a dietary supplement, mix 1 scoop with 6-10 ounces of water, or as directed by your physician.
Precautions
Warning: This product is only intended to be consumed by healthy individuals 18 years of age of older.
Consult your physician prior to use if you are pregnant or nursing. Consult your physician prior to use if you are taking any medications or have any medical condition.
Do not exceed recommended use. Improper use will not improve results. Discontinue use and seek professional assistance immediately if you experience unwanted side effects. Discontinue use 2 weeks prior to surgery. Do not use if safety seal is broken or missing.
Keep out of reach of children.
Storage
Store in a cool, dry place.
General Statements
Contents are sold by weight not volume. Some settling may occur.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
CCOF Certified Organic USDA Organic
Non GMO Gluten free product
Formula
Organic Shiitake Mushroom 7.5 g per serving Unflavored
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Nutricost Quality guaranteed Made in the USA
CCOF Certified Organic USDA Organic
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Organic Shiitake Mushroom 7.5 g Unflavored by Nutricost label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Organic Shiitake Mushroom 7.5 g Unflavored by Nutricost
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size7.5 Gram(s) Dosage formPowder Servings per container13 Amounts shown are per serving.
Organic Shiitake Mushroom
Interacts with312 drugs
Shiitake is a popular edible mushroom that is nutritious and safe to eat as food for most people. Some of its extracts (like lentinan and AHCC) have b...
Organic Shiitake Mushroom monograph & interactionsOther (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
Organic Shiitake Mushroom 7.5 g Unflavored by Nutricost Drug Interactions
HelloPharmacist Interaction Report
Nutricost Organic Shiitake Mushroom Powder does interact with medications through its shiitake mushroom content.
The most serious concern is with immunosuppressants (drugs that tame down the immune system after organ transplants or for autoimmune conditions). Shiitake may reduce how well these medications work by stimulating immune function, which could potentially compromise transplant outcomes or disease control.
Read the full breakdown — every affected drug type, severity by severity
Shiitake also affects how your body processes certain psychiatric and cardiac medications broken down by the CYP2D6 enzyme (a liver pathway). The mushroom extract in supplements may speed up how quickly your body clears these drugs, potentially lowering their effectiveness — though this effect has only been seen in lab studies, not yet confirmed in people.
Altogether, these interactions span 312 individual medications. Use the interaction checker below to search your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Organic Shiitake Mushroom 7.5 g Unflavored?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Organic Shiitake Mushroom 7.5 g Unflavored interact with 312 drugs. Click any drug to see the details.
1 of the 1 ingredient in Organic Shiitake Mushroom 7.5 g Unflavored interact with drugs. Each result below shows which ingredient is responsible. organic Shiitake Mushroom
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomImmunosuppressants Moderate
Interaction Summary
Theoretically, taking shiitake mushroom might decrease the effects of immunosuppressive therapy.
Read the full Organic Shiitake Mushroom + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomImmunosuppressants Moderate
Interaction Summary
Theoretically, taking shiitake mushroom might decrease the effects of immunosuppressive therapy.
Read the full Organic Shiitake Mushroom + Abrocitinib interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, DextromethorphanTylenol Cough Ex Strength
How Acetaminophen, Dextromethorphan interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Dextromethorphan interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylephrineConar-A
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylephrine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Hydrocodone interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Oxycodone interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Organic Shiitake Mushroom 7.5 g Unflavored — through 1 ingredient. Tap an ingredient for the detail:
Organic Shiitake MushroomCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
Read the full Organic Shiitake Mushroom + Acetaminophen, Propoxyphene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Organic Shiitake Mushroom 7.5 g Unflavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Shiitake Mushroom
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, shiitake mushroom might decrease levels of drugs metabolized by CYP2D6.
In vitro studies suggest that the shiitake mushroom extract AHCC might induce the CYP2D6 enzyme. This effect has not been reported in humans.
Immunosuppressants
Theoretically, taking shiitake mushroom might decrease the effects of immunosuppressive therapy.
In vitro evidence suggests that shiitake mushroom extracts stimulate immune function.
Brand information
Manufacturer and brand details for Organic Shiitake Mushroom 7.5 g Unflavored, from the product label.
Nutricost
See all Nutricost products- Name
- Nutricost
- Street Address
- 351 E 1750 N
- City
- Vineyard
- State
- UT
- ZipCode
- 84059
- Phone Number
- (866) 438-3694
- Web Address
- www.nutricost.com
Organic Shiitake Mushroom 7.5 g Unflavored by Nutricost: Common Questions
Does Organic Shiitake Mushroom 7.5 g Unflavored by Nutricost interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What's the difference between this powder and eating shiitake mushrooms at dinner?
What side effects should I watch for?
Does this actually help with cancer or chemotherapy side effects?
Can I take this with my transplant medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Organic Shiitake Mushroom 7.5 g Unflavored is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Organic Shiitake Mushroom 7.5 g Unflavored’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Organic Shiitake Mushroom 7.5 g Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 67 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Shiitake Mushroom 67 references
- Hitosugi M, Kitamura O, Takatsu A, Yoshino Y. Autopsy case of duodenal obstruction from impacted mushroom. J Gastroenterol 1998;33:562-5. PubMed
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