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Dietary supplement

Osha Root Rocky Mountain Throat Syrup Ingredients & Drug Interactions

by Herbs, Etc

Osha Root Rocky Mountain Throat Syrup label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Osha Root Rocky Mountain Throat Syrup against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Osha Root Rocky Mountain Throat Syrup is a dietary supplement by Herbs, Etc with 1 active ingredient. Its ingredients are commonly taken for cough and sore throat, respiratory infections and colds, immune support.Based on those ingredients, 715 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Osha Root Rocky Mountain Throat Syrup by Herbs, Etc

Ask about any prescription or over-the-counter medication and we check it for interactions with Osha Root Rocky Mountain Throat Syrup by Herbs, Etc — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Osha Root Rocky Mountain Throat Syrup by Herbs, Etc

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (5 mL) without saying how much of each component you get.
  • “Osha extract” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This is a 5-ingredient formula. The main players are Osha extract — a proprietary blend — plus Bloodroot, White Pine, Wild Cherry, Spikenard, and Balsam Poplar.

The product also contains inactive ingredients: evaporated cane juice, purified water, vegetable glycerin, and USP alcohol. So you're getting a liquid herbal blend with alcohol as part of the base.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Soothing cough syrup for sinus, throat, bronchiole and lung health.
  • We looked for evidence on: Cough, Sore throat, Bronchitis, Respiratory infection.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The data we hold shows effectiveness ratings only for Bloodroot in this formula. Bloodroot is rated Possibly Effective for dental plaque and gingivitis — meaning there's some evidence it may help with those conditions.

For periodontitis (deep gum infection), the evidence is insufficient to rate it either way. We have no effectiveness data on file for the other active ingredients in this product.

The evidence, ingredient by ingredient Osha

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bloodroot comes with serious cautions. It's potentially toxic and can corrode tissue — we do not recommend it for self-treatment.

Short-term oral use in appropriate doses is generally well tolerated, but nausea, vomiting, and central nervous system depression have been reported. High doses can cause low blood pressure, shock, and coma.

Long-term use in toothpaste or mouthwash has been linked to mouth lesions, taste problems, and tooth staining. Topically, it can cause severe pain, burning, skin erosion, and scarring.

Wild Cherry contains cyanide-forming compounds. Small amounts in commercial products are considered safe, but large amounts can cause cyanide poisoning — potentially fatal.

Pregnancy safety is a concern for both Bloodroot (likely unsafe) and Wild Cherry (likely unsafe). Bloodroot is possibly unsafe while breastfeeding; Wild Cherry safety data is not established for breastfeeding.

White Pine, Spikenard, and Balsam Poplar safety information is not on file.

Side effects, ingredient by ingredient Osha

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — American Spikenard, Wild Cherry.
  • The most serious interaction on file is rated Moderate.
  • For scale: 716 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take medications broken down by the enzyme CYP3A4 — including statins, antifungals, and many others — check them against the tool on this page before using this syrup. Wild Cherry can potentially slow how your body clears these drugs, though it hasn't been confirmed to cause a problem in humans yet.

No other documented interactions are on file for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a throat syrup built around ingredients with a long history in herbal medicine, but Bloodroot and Wild Cherry both carry real safety cautions — especially Bloodroot, which we don't recommend for self-treatment due to its toxicity and corrosive potential. If you're pregnant or breastfeeding, talk to your pharmacist or doctor before using it.

Check your medications against the interaction tool before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Osha Root Rocky Mountain Throat Syrup, straight from the product label.

Brand Herbs, Etc
Net contents 8 Fluid Ounce; 236 mL
Market status On market
Date entered into DSLD Apr 11, 2022
DSLD ID 261552
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Osha Root Rocky Mountain Throat Syrup by Herbs, Etc, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.25 mL
Maximum serving Sizes:
5 mL
Servings per container
47
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrate3 Gram(s)1%
Total Sugars3 Gram(s)--
added Sugars3 Gram(s)6%
Proprietary Extract Blend5 mL--
Osha extract0 NP--
Bloodroot0 NP--
White Pine0 NP--
Wild Cherry0 NP--
Spikenard0 NP--
Balsam Poplar0 NP--

Other ingredients: Evaporated cane juice, purified Water, Vegetable Glycerine, USP Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Value Size

Formulation

Herbal Medicine

Professional Strength Soothing Cough Syrup for Adults and Children Promotes Sinus, Throat, Bronchiole and Lung Health

Vegan Friendly

No artificial sweeteners, preservatives, corn syrup, colors, or flavors added.

Organic

Gluten Free

All herbs used in this syrup are sourced from the USA. Made in the USA.

Rocky Mountain Throat Syrup is a proven herbal formulation. Osha root, the leading ingredient, has provided generations of Southwestern people with respiratory support, including stopping the urge to cough, thinning mucus and opening up the sinuses.

Formulated by Daniel Gagnon, Medical Herbalist

Seals/Symbols

Proudly made in USA

FDA Statement of Identity

Fast-Acting Herbal Supplement

Brand IP Statement(s)

Suggested Use: Adults and Children 12 years of age and older: Take 1 teaspoon every three hours. Children 5-12 years of age: Take 1/2 teaspoon every three hours. Children 2-5 years of age: Take 1/4 teaspoon every three hours. Children younger than 2 years of age: Consult a healthcare provider before using.

Precautions

Caution: Do not use during pregnancy.

California Residents Only: This product contains a substance known to the State of California to cause birth defects or other reproductive harm.

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any diseases.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Osha Root Rocky Mountain Throat Syrup by Herbs, Etc label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Osha Root Rocky Mountain Throat Syrup label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Osha Root Rocky Mountain Throat Syrup by Herbs, Etc

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.25 mL Dosage formLiquid Servings per container47 Amounts shown are per serving.

Proprietary Extract Blend

5 mL per serving

Other (inactive) ingredients: Evaporated cane juice, Purified Water, Vegetable Glycerine, USP Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Osha Root Rocky Mountain Throat Syrup by Herbs, Etc Drug Interactions

Want to check YOUR meds against Osha Root Rocky Mountain Throat Syrup?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
715Drugs
643 Moderate 72 Minor

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Osha Root Rocky Mountain Throat Syrup interact with 715 drugs. Click any drug to see the details.

0 of the 1 ingredient in Osha Root Rocky Mountain Throat Syrup interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Osha Root Rocky Mountain Throat Syrup with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Osha Root Rocky Mountain Throat Syrup, from the product label.

Herbs, Etc

Name
Herbs, Etc.
Street Address
1340 Rufina Circle
City
Santa Fe
State
NM
ZipCode
87507
Web Address
www.herbsetc.com
Pharmacist Counseling Corner

Osha Root Rocky Mountain Throat Syrup by Herbs, Etc: Common Questions

Does Osha Root Rocky Mountain Throat Syrup by Herbs, Etc interact with any medications?
Yes. Based on its ingredients, Osha Root Rocky Mountain Throat Syrup has a known interaction with 715 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Osha Root Rocky Mountain Throat Syrup contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to use if I'm pregnant or breastfeeding?
No. Bloodroot is likely unsafe in pregnancy and possibly unsafe while breastfeeding. Wild Cherry is also likely unsafe in pregnancy, and its safety while breastfeeding hasn't been established. Talk to your doctor or pharmacist about what's safe for you right now.
What is Bloodroot doing in a throat syrup if it's that risky?
Bloodroot is rated Possibly Effective for dental plaque and gingivitis — it has some evidence behind it. But the data we hold shows it's also potentially toxic and corrosive, which is why we flag it. The formula is meant for short-term use; long-term daily use is where the serious mouth problems show up.
Can Wild Cherry actually poison me if I take this syrup?
The cyanide-forming compounds in Wild Cherry are a concern mainly at high doses — a case of poisoning involved consuming about 300 grams of fresh wild cherries. This syrup uses small amounts in a commercial formula, which is generally considered safe, but the plant should not be used in large amounts.
Does this actually work for a sore throat?
The effectiveness data we hold covers Bloodroot for dental plaque and gingivitis, not sore throat. We have no effectiveness ratings on file for the other ingredients in this blend, so I can't tell you from our data whether it will help your throat specifically.
What about the Osha root — what's it for?
Osha extract is the lead ingredient, but it's listed as a proprietary blend. We don't have separate effectiveness or safety data on file for it — only for the other named ingredients in the formula.
I take a statin for cholesterol — should I be worried?
Wild Cherry may slow how your body breaks down statins like lovastatin. It's a Moderate-severity interaction theoretically, though it hasn't been reported in actual people yet. Check your exact medication name in the search tool on this page to be sure, then talk to your pharmacist before you start the syrup.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Osha Root Rocky Mountain Throat Syrup is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Osha Root Rocky Mountain Throat Syrup label
Go deeper

The Full Monographs Behind Osha Root Rocky Mountain Throat Syrup’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Osha

Osha is a root from a wild mountain plant native to the western United States and Mexico, traditionally used by Native American and Hispanic communities for coughs, colds, and sore throats....

Read the full Osha monograph →
Sources

Sources & How We Checked

Osha Root Rocky Mountain Throat Syrup's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Osha 2 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Osha monograph →

Bloodroot 17 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Tenenbaum, H., Dahan, M., and Soell, M. Effectiveness of a sanguinarine regimen after scaling and root planing. J Periodontol. 1999;70(3):307-311. PubMed
  6. Eversole, L. R., Eversole, G. M., and Kopcik, J. Sanguinaria-associated oral leukoplakia: comparison with other benign and dysplastic leukoplakic lesions. Oral Surg.Oral Med.Oral Pathol.Oral Radiol.Endod. 2000;89(4):455-464. PubMed
  7. Allen, C. L., Loudon, J., and Mascarenhas, A. K. Sanguinaria-related leukoplakia: epidemiologic and clinicopathologic features of a recently described entity. Gen.Dent. 2001;49(6):608-614.
  8. Kopczyk, R. A., Abrams, H., Brown, A. T., Matheny, J. L., and Kaplan, A. L. Clinical and microbiological effects of a sanguinaria-containing mouthrinse and dentifrice with and without fluoride during 6 months of use. J.Periodontol. 1991;62(10):617-622. PubMed
  9. Harper, D. S., Mueller, L. J., Fine, J. B., Gordon, J., and Laster, L. L. Clinical efficacy of a dentifrice and oral rinse containing sanguinaria extract and zinc chloride during 6 months of use. J.Periodontol. 1990;61(6):352-358. PubMed
  10. Kuftinec, M. M., Mueller-Joseph, L. J., and Kopczyk, R. A. Sanguinaria toothpaste and oral rinse regimen clinical efficacy in short- and long-term trials. J.Can.Dent.Assoc. 1990;56(7 Suppl):31-33.
  11. Frankos, V. H., Brusick, D. J., Johnson, E. M., Maibach, H. I., Munro, I., Squire, R. A., and Weil, C. S. Safety of Sanguinaria extract as used in commercial toothpaste and oral rinse products. J.Can.Dent.Assoc. 1990;56(7 Suppl):41-47.
  12. Cullinan, M. P., Powell, R. N., Faddy, M. J., and Seymour, G. J. Efficacy of a dentifrice and oral rinse containing sanguinaria extract in conjunction with initial periodontal therapy. Aust.Dent.J. 1997;42(1):47-51. PubMed
  13. Affleck, A. G. and Varma, S. A case of do-it-yourself Mohs' surgery using bloodroot obtained from the internet. Br.J Dermatol 2007;157(5):1078-1079. PubMed
  14. Cienki JJ, Zaret L. An Internet misadventure: bloodroot salve toxicity. J Altern Complement Med. 2010;16(10):1125-7. PubMed
  15. Hou JL, Brewer JD. Black salve and bloodroot extract in dermatologic conditions. Cutis. 2015;95(6):309-11.
  16. Schilling LM, Saedi N. Bloodroot paste: what dermatologists and patients need to know. Dermatol Surg 2016;42(10):1223-4. PubMed
  17. Schlichte MJ, Downing CP, Ramirez-Fort M, Gordon R, Tyring S. Bloodroot associated eschar. Dermatol Online J 2014;20(7). DOI

See these in context on the Bloodroot monograph →

Wild Cherry 4 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  4. Pentore, R., Venneri, A., and Nichelli, P. Accidental choke-cherry poisoning: early symptoms and neurological sequelae of an unusual case of cyanide intoxication. Ital.J Neurol.Sci. 1996;17(3):233-235. PubMed

See these in context on the Wild Cherry monograph →

American Spikenard 1 reference
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

See these in context on the American Spikenard monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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