Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Osha Root Rocky Mountain Throat Syrup Ingredients & Drug Interactions

by Herbs Etc.

Osha Root Rocky Mountain Throat Syrup label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Osha Root Rocky Mountain Throat Syrup against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Osha Root Rocky Mountain Throat Syrup is a dietary supplement by Herbs Etc. with 6 active ingredients. Its ingredients are commonly taken for cough and sore throat, respiratory infections and colds, immune support.Based on those ingredients, 717 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wild Cherry bark extract, Spikenard root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Osha Root Rocky Mountain Throat Syrup by Herbs Etc.

Ask about any prescription or over-the-counter medication and we check it for interactions with Osha Root Rocky Mountain Throat Syrup by Herbs Etc. — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Osha Root Rocky Mountain Throat Syrup by Herbs Etc.

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 6, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 6 active ingredients.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (5 mL) without saying how much of each component you get.

This 6-ingredient liquid contains a proprietary extract blend whose components are listed separately. The active ingredients are osha root extract, white pine bark extract, wild cherry bark extract, spikenard root extract, balsam poplar bud extract, and bloodroot root extract.

The inactive ingredients — sugar, purified water, glycerine, and alcohol — are excipients that give the syrup its form and preserve it.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: soothing cough syrup for respiratory health.
  • We looked for evidence on: Asthma, Bronchitis, Common cold, Cough, sore throat, chest congestion — and 1 related terms.
  • The closest evidence on file: American Spikenard is rated "Insufficient Reliable Evidence To Rate" for Asthma (Natural Medicines).
  • Also on file: American Spikenard is rated "Insufficient Reliable Evidence To Rate" for Common cold.
  • Also on file: Wild Cherry is rated "Insufficient Reliable Evidence To Rate" for Bronchitis, Common cold, Cough.

The evidence for most uses isn't established in our data. Osha root is rated insufficient evidence for dyspepsia and HIV/AIDS.

Wild cherry bark is similarly unproven for bronchitis, common cold, cough, diabetes, and cancer. Spikenard root lacks reliable evidence for asthma and common cold.

Bloodroot is possibly effective for dental plaque and gingivitis, but insufficient evidence supports its use for IBS or periodontitis. Overall, this product's effectiveness for throat symptoms specifically is not rated in the data we hold.

The evidence, ingredient by ingredient Osha Wild Cherry American Spikenard Bloodroot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Several safety flags warrant attention. Wild cherry bark contains cyanide-forming compounds — small amounts in commercial products are considered safe, but large doses can cause serious poisoning.

Bloodroot is potentially toxic and corrosive; the data advises against self-treatment with it. Osha root has limited safety data, and wild osha can be confused with poisonous look-alike plants, so caution is needed.

For pregnancy: osha root, wild cherry bark, and bloodroot are all rated likely unsafe; spikenard root is possibly unsafe. For breastfeeding: osha root, wild cherry bark, spikenard root, and bloodroot all lack adequate safety data and should be avoided.

Bloodroot carries the additional concern of potential toxicity while nursing.

Side effects, ingredient by ingredient Osha Wild Cherry American Spikenard Bloodroot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 4 matched ingredients can interact with medications — American Spikenard, Wild Cherry.
  • The most serious interaction on file is rated Moderate.
  • For scale: 718 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take a diuretic (water pill), spikenard root may enhance its effects and raise your risk of dehydration and electrolyte problems. Wild cherry bark can inhibit the enzyme that metabolizes drugs like lovastatin and certain antifungals, potentially raising their levels — check with your pharmacist whether any of your medications are affected by CYP3A4 inhibition.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This syrup combines several traditionally used throat herbs, but the evidence for its effectiveness is not established in our data, and pregnancy and breastfeeding safety are concerns for most ingredients. If you take diuretics, any medications broken down by the enzyme CYP3A4 (like certain statins or antifungals), or are pregnant or nursing, talk with your doctor or pharmacist before using it.

Because this product contains ingredients with limited modern safety data and potential toxicity at higher doses, discuss it with your healthcare provider to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Osha Root Rocky Mountain Throat Syrup, straight from the product label.

Brand Herbs Etc.
Net contents 8 Fluid Ounce(s); 236 mL
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 320875
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Osha Root Rocky Mountain Throat Syrup by Herbs Etc., sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 mL, 2.5 mL, 1.25 mL
Maximum serving Sizes:
5 mL, 2.5 mL, 1.25 mL
Servings per container
47
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates3 Gram(s)1%
Added Sugars3 Gram(s)6%
Total Sugars3 Gram(s)--
Proprietary Extract Blend5 mL--
Osha root extract0 NP--
White Pine bark extract0 NP--
Wild Cherry bark extract0 NP--
Spikenard root extract0 NP--
Balsam Poplar Bud Extract0 NP--
Bloodroot Root Extract0 NP--

Other ingredients: Sugar, Water, Purified, Glycerine, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Herbal medicine Soothing cough syrup for adults and children Deliciously powerful formula comforts the throat Promotes sinus, throat, bronchiole and lung health

Gluten free

Vegan

Sinuses Throat Bronchioles Lungs Powerful respiratory support Rocky Mountain Throat Syrup is a powerful cough syrup that soothes and comforts throat tissues. This formula promotes sinus, throat, bronchiole and lung health.

No artificial sweeteners, corn syrup, colors or flavors added. No preservatives. Gluten free

Vegan

Manufactured in Santa Fe, NM.

Seals/Symbols

Vegan

FDA Statement of Identity

Herbal Supplement

Formula

Osha root, an important ingredient in this herbal medicine, has been used by generations of Southwestern Native Americans and Hispanics to support their respiratory health. We believe Osha root is the must-have herb, which is why we include it in our throat syrup. Our commitment to Osha root goes beyond our belief in its medicinal qualities. Herbs, Etc. works with plant preservationists to ensure the sustainability of this important botanical. Learn more about this ongoing project by visiting Herbs, Etc.'s Rocky Mountain Throat Syrup pages at herbsetc.com.

Soothing cough syrup for adults and children

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

Brand IP Statement(s)

Herbal Medicines Made Right We do all of this to bring you herbal medicines made right. Daniel Gagnon Medical Herbalist and President of Herbs, Etc.

General Statements

We apply our company philosophy to Rocky Mountain Throat Syrup, as we do to all of our herbal medicines. That philosophy is to do what's right, which extends to identifying and choosing the right herbs, using the right machines and processes and making the right liquid extracts. We focus solely on providing you with the right active constituent-rich formulations that support your health needs. Each herbal medicine is released only after it goes through rigorous quality control to ensure safety and satisfaction.

Facebook.com/herbsetc

Value size

Suggested/Recommended/Usage/Directions

Suggested use: Adults and children 12 years of age and older: Take 1 teaspoon every 3 hours. Children 5-12 years of age: Take 1/2 teaspoon every 3 hours. Children 2-5 years of age: Take 1/4 teaspoon every 3 hours.

Precautions

Children younger than 2 years of age: Consult a healthcare provider before using.

Caution: Do not use during pregnancy.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Osha Root Rocky Mountain Throat Syrup by Herbs Etc. label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Osha Root Rocky Mountain Throat Syrup label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Osha Root Rocky Mountain Throat Syrup by Herbs Etc.

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size5 mL Dosage formLiquid Servings per container47 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Extract Blend

5 mL per serving

Other (inactive) ingredients: Sugar, Water, Purified, Glycerine, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Osha Root Rocky Mountain Throat Syrup by Herbs Etc. Drug Interactions

Want to check YOUR meds against Osha Root Rocky Mountain Throat Syrup?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
717Drugs
645 Moderate 72 Minor

Ingredients driving the most interactions

Wild Cherry bark extract 645
Spikenard root extract 75

Individual Drug Interactions

The ingredients in Osha Root Rocky Mountain Throat Syrup interact with 717 drugs. Click any drug to see the details.

2 of the 6 ingredients in Osha Root Rocky Mountain Throat Syrup interact with drugs. Each result below shows which ingredient is responsible. Wild Cherry bark extract Spikenard root extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Osha Root Rocky Mountain Throat Syrup with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Wild Cherry bark extract1 drug type · 645 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro research suggests that wild cherry can inhibit cytochrome P450 3A4 (CYP3A4) enzymes. Theoretically, wild cherry might increase levels of drugs metabolized by CYP3A4. However, so far, this interaction has not been reported in humans.
Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and others.

Likelihood Possible Evidence D
Wild Cherry bark extract full monograph & interactions

Spikenard root extract1 drug type · 75 drugs

Diuretic Drugs

American spikenard is purported to have diaphoretic properties. Diaphoretic substances can increase sweating and fluid loss from the body, which may enhance the effects of diuretics. This interaction could potentially lead to excessive fluid loss and electrolyte imbalance, especially in individuals taking diuretic medications. Healthcare providers need to monitor patients closely for signs of dehydration or electrolyte disturbances if they are using both Aralia racemosa and diuretic drugs concurrently.

Likelihood Possible Evidence D
Spikenard root extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Osha Root Rocky Mountain Throat Syrup, from the product label.

Herbs Etc.

Name
Herbs, Etc., Inc.
Street Address
1340 Rufina Circle
City
Santa Fe
State
NM
ZipCode
87507
Web Address
www.herbsetc.com
Pharmacist Counseling Corner

Osha Root Rocky Mountain Throat Syrup by Herbs Etc.: Common Questions

Does Osha Root Rocky Mountain Throat Syrup by Herbs Etc. interact with any medications?
Yes. Based on its ingredients, Osha Root Rocky Mountain Throat Syrup has a known interaction with 717 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Osha Root Rocky Mountain Throat Syrup contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant?
No — several ingredients in this syrup, including osha root, wild cherry bark, and bloodroot, are rated likely unsafe in pregnancy. Spikenard root is possibly unsafe. Talk with your doctor or pharmacist before using it if you're pregnant or planning to become pregnant.
What about while breastfeeding?
The safety data advise against it. Osha root, wild cherry bark, spikenard root, and bloodroot all lack sufficient safety information for nursing, and bloodroot carries additional concerns about potential toxicity. Speak with your doctor or pharmacist for guidance.
Does this actually work for sore throats or coughs?
The evidence for cough and common cold relief isn't established in our data. Wild cherry bark and spikenard root are both unproven for cough and cold symptoms. While these are traditional throat remedies, we don't have reliable evidence they work.
What's bloodroot, and why is it in here if it's potentially toxic?
Bloodroot is a plant root traditionally used in small amounts in throat products. The data show it's possibly effective for dental plaque and gingivitis, but it's also potentially toxic and corrosive — the product facts advise against self-treatment with it, so use caution and stick to recommended doses.
Why does the data say I need to watch out for 718 medications?
Wild cherry bark can slow the liver's breakdown of many drugs through one enzyme pathway. That single ingredient theoretically affects hundreds of medications metabolized that way — though the interaction hasn't been confirmed to cause harm in humans yet. Use the medication checker to see if any of yours are on that list.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Osha Root Rocky Mountain Throat Syrup is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Osha Root Rocky Mountain Throat Syrup label
Go deeper

The Full Monographs Behind Osha Root Rocky Mountain Throat Syrup’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Osha

Osha is a root from a wild mountain plant native to the western United States and Mexico, traditionally used by Native American and Hispanic communities for coughs, colds, and sore throats....

Read the full Osha monograph → Herb & supplement monograph

Wild Cherry

Interacts with 645 drugs

Wild cherry bark is a traditional cough remedy found in many old-fashioned cough syrups and lozenges, but there is little modern scientific evidence proving it works. The bark, leaves, and s...

Read the full Wild Cherry monograph → Herb & supplement monograph

American Spikenard

Interacts with 75 drugs

American spikenard is a traditional North American herb used mainly as an expectorant and to ease coughs and colds, but there is no reliable human research to confirm it works. If you choose...

Read the full American Spikenard monograph → Herb & supplement monograph

Bloodroot

Bloodroot is a North American plant whose red root sap contains potent alkaloids that are corrosive to skin and tissue. It has a long folk history, but there is no good evidence it safely tr...

Read the full Bloodroot monograph →
Sources

Sources & How We Checked

Osha Root Rocky Mountain Throat Syrup's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Osha 2 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Osha monograph →

Wild Cherry 4 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  4. Pentore, R., Venneri, A., and Nichelli, P. Accidental choke-cherry poisoning: early symptoms and neurological sequelae of an unusual case of cyanide intoxication. Ital.J Neurol.Sci. 1996;17(3):233-235. PubMed

See these in context on the Wild Cherry monograph →

American Spikenard 1 reference
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

See these in context on the American Spikenard monograph →

Bloodroot 14 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Eversole, L. R., Eversole, G. M., and Kopcik, J. Sanguinaria-associated oral leukoplakia: comparison with other benign and dysplastic leukoplakic lesions. Oral Surg.Oral Med.Oral Pathol.Oral Radiol.Endod. 2000;89(4):455-464. PubMed
  6. Allen, C. L., Loudon, J., and Mascarenhas, A. K. Sanguinaria-related leukoplakia: epidemiologic and clinicopathologic features of a recently described entity. Gen.Dent. 2001;49(6):608-614.
  7. Kuftinec, M. M., Mueller-Joseph, L. J., and Kopczyk, R. A. Sanguinaria toothpaste and oral rinse regimen clinical efficacy in short- and long-term trials. J.Can.Dent.Assoc. 1990;56(7 Suppl):31-33.
  8. Frankos, V. H., Brusick, D. J., Johnson, E. M., Maibach, H. I., Munro, I., Squire, R. A., and Weil, C. S. Safety of Sanguinaria extract as used in commercial toothpaste and oral rinse products. J.Can.Dent.Assoc. 1990;56(7 Suppl):41-47.
  9. Cullinan, M. P., Powell, R. N., Faddy, M. J., and Seymour, G. J. Efficacy of a dentifrice and oral rinse containing sanguinaria extract in conjunction with initial periodontal therapy. Aust.Dent.J. 1997;42(1):47-51. PubMed
  10. Affleck, A. G. and Varma, S. A case of do-it-yourself Mohs' surgery using bloodroot obtained from the internet. Br.J Dermatol 2007;157(5):1078-1079. PubMed
  11. Cienki JJ, Zaret L. An Internet misadventure: bloodroot salve toxicity. J Altern Complement Med. 2010;16(10):1125-7. PubMed
  12. Hou JL, Brewer JD. Black salve and bloodroot extract in dermatologic conditions. Cutis. 2015;95(6):309-11.
  13. Schilling LM, Saedi N. Bloodroot paste: what dermatologists and patients need to know. Dermatol Surg 2016;42(10):1223-4. PubMed
  14. Schlichte MJ, Downing CP, Ramirez-Fort M, Gordon R, Tyring S. Bloodroot associated eschar. Dermatol Online J 2014;20(7). DOI

See these in context on the Bloodroot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team